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5XVR
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BU of 5xvr by Molmil
EarP bound with dTDP-rhamnose (co-crystal)
分子名称: 2'-DEOXY-THYMIDINE-BETA-L-RHAMNOSE, EarP, SULFATE ION
著者Sengoku, T, Yokoyama, S, Yanagisawa, T.
登録日2017-06-28
公開日2018-02-28
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Structural basis of protein arginine rhamnosylation by glycosyltransferase EarP
Nat. Chem. Biol., 14, 2018
3WHE
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BU of 3whe by Molmil
A new conserved neutralizing epitope at the globular head of hemagglutinin in H3N2 influenza viruses
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Fujii, Y, Sumida, T, Shirouzu, M, Yokoyama, S.
登録日2013-08-25
公開日2014-04-23
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Conserved neutralizing epitope at globular head of hemagglutinin in H3N2 influenza viruses.
J.Virol., 88, 2014
2QQ3
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BU of 2qq3 by Molmil
Crystal Structure Of Enoyl-CoA Hydrates Subunit I (gk_2039) Other Form From Geobacillus Kaustophilus HTA426
分子名称: 1,2-ETHANEDIOL, Enoyl-CoA hydratase subunit I
著者Jeyakanthan, J, Kanaujia, S.P, Sekar, K, Ebihara, A, Shinkai, A, Kuramitsu, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-07-26
公開日2008-07-29
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal Structure Of Enoyl-CoA Hydrates Subunit I (gk_2039) Other Form From Geobacillus Kaustophilus HTA426
To be Published
6JP2
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BU of 6jp2 by Molmil
Crystal structure of pyrrolysyl-tRNA synthetase from Methanomethylophilus alvus
分子名称: Pyrrolysyl-tRNA synthetase
著者Yanagisawa, T, Kuratani, M, Yokoyama, S.
登録日2019-03-25
公開日2019-05-22
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.272 Å)
主引用文献Fully Productive Cell-Free Genetic Code Expansion by Structure-Based Engineering ofMethanomethylophilus alvusPyrrolysyl-tRNA Synthetase.
Acs Synth Biol, 9, 2020
3WJ9
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BU of 3wj9 by Molmil
Crystal structure of the eukaryotic initiation factor
分子名称: Eukaryotic translation initiation factor 2A
著者Kashiwagi, K, Ito, T, Yokoyama, S.
登録日2013-10-07
公開日2014-03-12
最終更新日2022-08-24
実験手法X-RAY DIFFRACTION (2.506 Å)
主引用文献Crystal structure of the eukaryotic translation initiation factor 2A from Schizosaccharomyces pombe.
J Struct Funct Genomics, 15, 2014
3WU5
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BU of 3wu5 by Molmil
Reduced E.coli Lon Proteolytic domain
分子名称: Lon protease, SULFATE ION
著者Nishii, W, Kukimoto-Niino, M, Terada, T, Shirouzu, M, Muramatsu, T, Yokoyama, S.
登録日2014-04-22
公開日2014-11-12
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献A redox switch shapes the Lon protease exit pore to facultatively regulate proteolysis.
Nat. Chem. Biol., 11, 2015
3WU3
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BU of 3wu3 by Molmil
Reduced-form structure of E.coli Lon Proteolytic domain
分子名称: Lon protease, SULFATE ION
著者Nishii, W, Kukimoto-Niino, M, Terada, T, Shirouzu, M, Muramatsu, T, Yokoyama, S.
登録日2014-04-22
公開日2014-11-12
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献A redox switch shapes the Lon protease exit pore to facultatively regulate proteolysis.
Nat. Chem. Biol., 11, 2015
2RT9
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BU of 2rt9 by Molmil
Solution structure of a regulatory domain of meiosis inhibitor
分子名称: F-box only protein 43, ZINC ION
著者Shoji, S, Muto, Y, Ikeda, M, He, F, Tsuda, K, Ohsawa, N, Akasaka, R, Terada, T, Wakiyama, M, Shirouzu, M, Yokoyama, S.
登録日2013-07-05
公開日2014-07-16
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献The zinc-binding region (ZBR) fragment of Emi2 can inhibit APC/C by targeting its association with the coactivator Cdc20 and UBE2C-mediated ubiquitylation
FEBS Open Bio, 4, 2014
2RMX
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BU of 2rmx by Molmil
Solution structure of the SHP-1 C-terminal SH2 domain complexed with a tyrosine-phosphorylated peptide from NKG2A
分子名称: NKG2-A/NKG2-B type II integral membrane protein, Tyrosine-protein phosphatase non-receptor type 6
著者Kasai, T, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-11-30
公開日2008-12-02
最終更新日2022-03-16
実験手法SOLUTION NMR
主引用文献Structural basis for the recognition of the two NKG2A immunoreceptor tyrosine-based inhibitory motifs (ITIMs) by the C-terminal SH2 domain of protein tyrosine phosphatase SHP-1
To be Published
2ROK
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BU of 2rok by Molmil
Solution structure of the cap-binding domain of PARN complexed with the cap analog
分子名称: 7N-METHYL-8-HYDROGUANOSINE-5'-MONOPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, poly(A)-specific ribonuclease
著者Nagata, T, Suzuki, S, Endo, R, Shirouzu, M, Terada, T, Inoue, M, Kigawa, T, Guntert, P, Hayashizaki, Y, Muto, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2008-03-28
公開日2009-02-10
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献The RRM domain of poly(A)-specific ribonuclease has a noncanonical binding site for mRNA cap analog recognition.
Nucleic Acids Res., 36, 2008
5YVB
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BU of 5yvb by Molmil
Structure of CaMKK2 in complex with CKI-011
分子名称: (3Z)-5-chloro-3-[(1-methyl-1H-pyrazol-4-yl)methylidene]-1,3-dihydro-2H-indol-2-one, CHLORIDE ION, Calcium/calmodulin-dependent protein kinase kinase 2, ...
著者Niwa, H, Handa, N, Yokoyama, S.
登録日2017-11-24
公開日2018-12-05
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Protein ligand interaction analysis against new CaMKK2 inhibitors by use of X-ray crystallography and the fragment molecular orbital (FMO) method.
J.Mol.Graph.Model., 99, 2020
2RNL
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BU of 2rnl by Molmil
Solution structure of the EGF-like domain from human Amphiregulin
分子名称: Amphiregulin
著者Qin, X, Hayashi, F, Terada, T, Shirouzu, M, Watanabe, S, Kigawa, T, Yabuta, N, Nojima, H, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2008-01-11
公開日2009-01-20
最終更新日2022-03-16
実験手法SOLUTION NMR
主引用文献Solution structure of the EGF-like domain from human Amphiregulin
To be Published
2RSM
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BU of 2rsm by Molmil
Solution structure and siRNA-mediated knockdown analysis of the mitochondrial disease-related protein C12orf65 (ICT2)
分子名称: Probable peptide chain release factor C12orf65 homolog, mitochondrial
著者Enomoto, M, Tochio, N, Tomizawa, T, Koshiba, S, Guntert, P, Kigawa, T, Yokoyama, S, Nameki, N.
登録日2012-03-28
公開日2012-08-08
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution structure and siRNA-mediated knockdown analysis of the mitochondrial disease-related protein C12orf65.
Proteins, 2012
5YV9
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BU of 5yv9 by Molmil
Structure of CaMKK2 in complex with CKI-009
分子名称: 5-chloro-2-methoxy-4[(1Z)-3-(4-methoxyphenyl)-3-oxoprop-1-en-1-yl]aminobenzoic acid, CHLORIDE ION, Calcium/calmodulin-dependent protein kinase kinase 2, ...
著者Niwa, H, Handa, N, Yokoyama, S.
登録日2017-11-24
公開日2018-12-05
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.53 Å)
主引用文献Protein ligand interaction analysis against new CaMKK2 inhibitors by use of X-ray crystallography and the fragment molecular orbital (FMO) method.
J.Mol.Graph.Model., 99, 2020
2ROR
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BU of 2ror by Molmil
Solution structure of the VAV1 SH2 domain complexed with a tyrosine-phosphorylated peptide from SLP76
分子名称: 15-meric peptide from Lymphocyte cytosolic protein 2, Proto-oncogene vav
著者Tanaka, M, Kasai, T, Koshiba, S, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2008-04-08
公開日2009-04-21
最終更新日2022-03-16
実験手法SOLUTION NMR
主引用文献Solution structure of the VAV1 SH2 domain complexed with a tyrosine-phosphorylated peptide from SLP76
To be Published
6KS0
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BU of 6ks0 by Molmil
Crystal structure of the human adiponectin receptor 1
分子名称: Adiponectin receptor protein 1, PHOSPHATE ION, The heavy chain variable domain (Antibody), ...
著者Tanabe, H, Fujii, Y, Nakamura, Y, Hosaka, T, Okada-Iwabu, M, Iwabu, M, Kimura-Someya, T, Shirouzu, M, Yamauchi, T, Kadowaki, T, Yokoyama, S.
登録日2019-08-22
公開日2020-08-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.79 Å)
主引用文献Human adiponectin receptor AdipoR1 assumes closed and open structures.
Commun Biol, 3, 2020
6KS1
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BU of 6ks1 by Molmil
Crystal structure of the human adiponectin receptor 2
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-3-{[(R)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-hydroxypropyl hexadecanoate, ...
著者Tanabe, H, Fujii, Y, Nakamura, Y, Hosaka, T, Okada-Iwabu, M, Iwabu, M, Kimura-Someya, T, Shirouzu, M, Yamauchi, T, Kadowaki, T, Yokoyama, S.
登録日2019-08-22
公開日2020-08-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Human adiponectin receptor AdipoR1 assumes closed and open structures.
Commun Biol, 3, 2020
6KRZ
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BU of 6krz by Molmil
Crystal structure of the human adiponectin receptor 1 D208A mutant
分子名称: (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Adiponectin receptor protein 1, OLEIC ACID, ...
著者Tanabe, H, Fujii, Y, Okada-Iwabu, M, Iwabu, M, Yamauchi, T, Kadowaki, T, Yokoyama, S.
登録日2019-08-22
公開日2020-08-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Human adiponectin receptor AdipoR1 assumes closed and open structures.
Commun Biol, 3, 2020
6ABK
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BU of 6abk by Molmil
Crystal structure of Methanosarcina mazei PylRS(Y306A/Y384F) complexed with TeocLys
分子名称: (2S)-2-azanyl-6-(trimethylsilylmethoxycarbonylamino)hexanoic acid, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Yanagisawa, T, Kuratani, M, Yokoyama, S.
登録日2018-07-22
公開日2019-04-17
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Structural Basis for Genetic-Code Expansion with Bulky Lysine Derivatives by an Engineered Pyrrolysyl-tRNA Synthetase.
Cell Chem Biol, 26, 2019
6AAO
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BU of 6aao by Molmil
Crystal structure of Methanosarcina mazei PylRS(Y306A/Y384F) complexed with TCO*Lys
分子名称: ADENOSINE-5'-TRIPHOSPHATE, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ...
著者Yanagisawa, T, Kuratani, M, Yokoyama, S.
登録日2018-07-18
公開日2019-04-17
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.403 Å)
主引用文献Structural Basis for Genetic-Code Expansion with Bulky Lysine Derivatives by an Engineered Pyrrolysyl-tRNA Synthetase.
Cell Chem Biol, 26, 2019
6AB0
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BU of 6ab0 by Molmil
Crystal structure of Methanosarcina mazei PylRS(Y306A/Y384F) complexed with pAmPyLys
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, N6-{[(6-aminopyridin-3-yl)methoxy]carbonyl}-L-lysine, ...
著者Yanagisawa, T, Kuratani, M, Yokoyama, S.
登録日2018-07-19
公開日2019-04-17
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.441 Å)
主引用文献Structural Basis for Genetic-Code Expansion with Bulky Lysine Derivatives by an Engineered Pyrrolysyl-tRNA Synthetase.
Cell Chem Biol, 26, 2019
6AAP
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BU of 6aap by Molmil
Crystal structure of Methanosarcina mazei PylRS(Y306A/Y384F) complexed with ZaeSeCys
分子名称: 3-[(2-{[(benzyloxy)carbonyl]amino}ethyl)selanyl]-L-alanine, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Yanagisawa, T, Kuratani, M, Yokoyama, S.
登録日2018-07-18
公開日2019-04-17
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural Basis for Genetic-Code Expansion with Bulky Lysine Derivatives by an Engineered Pyrrolysyl-tRNA Synthetase.
Cell Chem Biol, 26, 2019
8IFJ
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BU of 8ifj by Molmil
Crystal structure of pyrrolysyl-tRNA synthetase from methanogenic archaeon ISO4-G1
分子名称: Pyrrolysyl-tRNA synthetase PylS
著者Yanagisawa, T, Tanabe, H, Yokoyama, S.
登録日2023-02-18
公開日2023-03-15
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.78 Å)
主引用文献Crystal Structure of Pyrrolysyl-tRNA Synthetase from a Methanogenic Archaeon ISO4-G1 and Its Structure-Based Engineering for Highly-Productive Cell-Free Genetic Code Expansion with Non-Canonical Amino Acids.
Int J Mol Sci, 24, 2023
6AAC
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BU of 6aac by Molmil
Crystal structure of Methanosarcina mazei PylRS(Y306A/Y384F) complexed with mAzZLys
分子名称: ADENOSINE-5'-TRIPHOSPHATE, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ...
著者Yanagisawa, T, Kuratani, M, Yokoyama, S.
登録日2018-07-18
公開日2019-04-17
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.479 Å)
主引用文献Structural Basis for Genetic-Code Expansion with Bulky Lysine Derivatives by an Engineered Pyrrolysyl-tRNA Synthetase.
Cell Chem Biol, 26, 2019
6AB1
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BU of 6ab1 by Molmil
Crystal structure of Methanosarcina mazei PylRS(Y306A/Y384F) complexed with oAzZLys
分子名称: (2S)-2-azanyl-6-[(2-azidophenyl)methoxycarbonylamino]hexanoic acid, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Yanagisawa, T, Kuratani, M, Yokoyama, S.
登録日2018-07-19
公開日2019-04-17
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.381 Å)
主引用文献Structural Basis for Genetic-Code Expansion with Bulky Lysine Derivatives by an Engineered Pyrrolysyl-tRNA Synthetase.
Cell Chem Biol, 26, 2019

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