2RT9

Solution structure of a regulatory domain of meiosis inhibitor

Summary for 2RT9

• Entry DOI: 10.2210/pdb2rt9/pdb
• NMR Information: BMRB: 11529
• Descriptor: F-box only protein 43, ZINC ION (2 entities in total)
• Functional Keywords: zinc-finger domain, metal binding protein
• Biological source: Mus musculus (mouse)
• Total number of polymer chains: 1
• Total formula weight: 6481.10

Authors

Shoji, S.,Muto, Y.,Ikeda, M.,He, F.,Tsuda, K.,Ohsawa, N.,Akasaka, R.,Terada, T.,Wakiyama, M.,Shirouzu, M.,Yokoyama, S. (deposition date: 2013-07-05, release date: 2014-07-16, Last modification date: 2015-01-21)

• Primary citation: Shoji, S.,Muto, Y.,Ikeda, M.,He, F.,Tsuda, K.,Ohsawa, N.,Akasaka, R.,Terada, T.,Wakiyama, M.,Shirouzu, M.,Yokoyama, S.; The zinc-binding region (ZBR) fragment of Emi2 can inhibit APC/C by targeting its association with the coactivator Cdc20 and UBE2C-mediated ubiquitylation; FEBS Open Bio, 4:689-703, 2014; PubMed: 25161877; DOI: 10.1016/j.fob.2014.06.010

Experimental method

SOLUTION NMR