8IFJ

Crystal structure of pyrrolysyl-tRNA synthetase from methanogenic archaeon ISO4-G1

Summary for 8IFJ

Entry DOI	10.2210/pdb8ifj/pdb
Descriptor	Pyrrolysyl-tRNA synthetase PylS (2 entities in total)
Functional Keywords	non-canonical amino acids, genetic code expansion, trna, translation
Biological source	methanogenic archaeon mixed culture ISO4-G1
Total number of polymer chains	10
Total formula weight	312564.69
Authors	Yanagisawa, T.,Tanabe, H.,Yokoyama, S. (deposition date: 2023-02-18, release date: 2023-03-15, Last modification date: 2023-04-26)
Primary citation	Yanagisawa, T.,Seki, E.,Tanabe, H.,Fujii, Y.,Sakamoto, K.,Yokoyama, S. Crystal Structure of Pyrrolysyl-tRNA Synthetase from a Methanogenic Archaeon ISO4-G1 and Its Structure-Based Engineering for Highly-Productive Cell-Free Genetic Code Expansion with Non-Canonical Amino Acids. Int J Mol Sci, 24:-, 2023 Cited by PubMed: 37047230 DOI: 10.3390/ijms24076256 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.78 Å)

Structure validation