7K9P
 
 | | Room temperature structure of NSP15 Endoribonuclease from SARS CoV-2 solved using SFX. | | 分子名称: | CITRIC ACID, Uridylate-specific endoribonuclease | | 著者 | Botha, S, Jernigan, R, Chen, J, Coleman, M.A, Frank, M, Grant, T.D, Hansen, D.T, Ketawala, G, Logeswaran, D, Martin-Garcia, J, Nagaratnam, N, Raj, A.L.L.X, Shelby, M, Yang, J.-H, Yung, M.C, Fromme, P. | | 登録日 | 2020-09-29 | | 公開日 | 2020-10-21 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Room-temperature structural studies of SARS-CoV-2 protein NendoU with an X-ray free-electron laser.
Structure, 2022
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3V9M
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2C1E
 | | Crystal structures of caspase-3 in complex with aza-peptide Michael acceptor inhibitors. | | 分子名称: | AZA-PEPTIDE INHIBITOR (5S, 8R, 11S)-8-(2-CARBOXYETHYL)-5-(CARBOXYMETHYL)-14-(4-ETHOXY-4-OXOBUTANOYL)-11-(1-METHYLETHYL)-3,6,9,12-TETRAOXO-1-PHENYL-2-OXA-4,7,10,13,14-PENTAAZAHEXADECAN -16-OIC ACID, ... | | 著者 | Grutter, M.G. | | 登録日 | 2005-09-14 | | 公開日 | 2006-09-20 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | | 主引用文献 | Design, Synthesis, and Evaluation of Aza-Peptide Michael Acceptors as Selective and Potent Inhibitors of Caspases-2, -3, -6, -7, -8, -9, and - 10.
J.Med.Chem., 49, 2006
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3O8A
 | | Crystal structure of Plasmodium falciparum dihydroorotate dehydrogenase bound with novel Inhibitor Genz667348 | | 分子名称: | Dihydroorotate dehydrogenase homolog, mitochondrial, FLAVIN MONONUCLEOTIDE, ... | | 著者 | Deng, X, Booker, M.L, Phillips, M.A. | | 登録日 | 2010-08-02 | | 公開日 | 2010-08-18 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Novel inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase with anti-malarial activity in the mouse model.
J.Biol.Chem., 285, 2010
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6KTH
 | | Crystal structure of Juvenile hormone diol kinase JHDK-L2 from silkworm, Bombyx mori | | 分子名称: | CALCIUM ION, GLYCEROL, Juvenile hormone diol kinase | | 著者 | Zhang, Y.S, Xu, H.Y, Wang, Z, Zhang, L, Zhao, P, Guo, P.C. | | 登録日 | 2019-08-28 | | 公開日 | 2020-09-02 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.22 Å) | | 主引用文献 | Structural characterization and functional analysis of juvenile hormone diol kinase from the silkworm, Bombyx mori.
Int.J.Biol.Macromol., 167, 2021
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2R0L
 | | Short Form HGFA with Inhibitory Fab75 | | 分子名称: | Hepatocyte growth factor activator, antibody heavy chain, Fab portion only, ... | | 著者 | Eigenbrot, C, Shia, S. | | 登録日 | 2007-08-20 | | 公開日 | 2007-12-25 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural insight into distinct mechanisms of protease inhibition by antibodies.
Proc.Natl.Acad.Sci.Usa, 104, 2007
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8F9E
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8F9S
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8F95
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8F9T
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8F9W
 | | Crystal structure of Ky15.8 Fab in complex with circumsporozoite protein NPDP peptide | | 分子名称: | 1,2-ETHANEDIOL, Circumsporozoite protein NPDP peptide, Ky15.8 Antibody, ... | | 著者 | Thai, E, Prieto, K, Julien, J.P. | | 登録日 | 2022-11-24 | | 公開日 | 2023-11-01 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Molecular determinants of cross-reactivity and potency by VH3-33 antibodies against the Plasmodium falciparum circumsporozoite protein.
Cell Rep, 42, 2023
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8FA6
 | | Crystal structure of Ky15.10 Fab in complex with circumsporozoite protein DND peptide | | 分子名称: | 1,2-ETHANEDIOL, Circumsporozoite protein DND peptide, Ky15.10 Antibody, ... | | 著者 | Thai, E, Prieto, K, Julien, J.P. | | 登録日 | 2022-11-25 | | 公開日 | 2023-11-01 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Molecular determinants of cross-reactivity and potency by VH3-33 antibodies against the Plasmodium falciparum circumsporozoite protein.
Cell Rep, 42, 2023
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8F9V
 | | Crystal structure of Ky15.8 Fab in complex with circumsporozoite protein KQPA peptide | | 分子名称: | 1,2-ETHANEDIOL, Circumsporozoite protein KQPA peptide, Ky15.8 Antibody, ... | | 著者 | Thai, E, Prieto, K, Julien, J.P. | | 登録日 | 2022-11-24 | | 公開日 | 2023-11-01 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Molecular determinants of cross-reactivity and potency by VH3-33 antibodies against the Plasmodium falciparum circumsporozoite protein.
Cell Rep, 42, 2023
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8FA7
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8F9F
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8FA9
 | | Crystal structure of Ky15.5 Fab in complex with circumsporozoite protein NPDP peptide | | 分子名称: | Circumsporozoite protein NPDP peptide, Ky15.5 Antibody, heavy chain, ... | | 著者 | Thai, E, Prieto, K, Julien, J.P. | | 登録日 | 2022-11-25 | | 公開日 | 2023-11-01 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Molecular determinants of cross-reactivity and potency by VH3-33 antibodies against the Plasmodium falciparum circumsporozoite protein.
Cell Rep, 42, 2023
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8F9U
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8FA8
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2R0K
 | | Protease domain of HGFA with inhibitor Fab58 | | 分子名称: | Hepatocyte growth factor activator, antibody heavy chain of Fab58, Fab portion only, ... | | 著者 | Eigenbrot, C, Shia, S. | | 登録日 | 2007-08-20 | | 公開日 | 2007-12-25 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (3.51 Å) | | 主引用文献 | Structural insight into distinct mechanisms of protease inhibition by antibodies.
Proc.Natl.Acad.Sci.Usa, 104, 2007
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7V05
 | | Complex of Plasmodium falciparum circumsporozoite protein with 850 Fab | | 分子名称: | 850 Fab Heavy Chain, 850 Fab Light Chain, Circumsporozoite protein | | 著者 | Kucharska, I, Prieto, K, Rubinstein, J.L, Julien, J.P. | | 登録日 | 2022-05-09 | | 公開日 | 2022-11-23 | | 最終更新日 | 2022-12-14 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | High-density binding to Plasmodium falciparum circumsporozoite protein repeats by inhibitory antibody elicited in mouse with human immunoglobulin repertoire.
Plos Pathog., 18, 2022
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7UYM
 | | 850 Fab in complex with NANPNANPNANP peptide | | 分子名称: | 850 Fab Heavy Chain, 850 Fab Light Chain, Circumsporozoite protein, ... | | 著者 | Kucharska, I, Prieto, K, Julien, J.P. | | 登録日 | 2022-05-06 | | 公開日 | 2022-11-23 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | High-density binding to Plasmodium falciparum circumsporozoite protein repeats by inhibitory antibody elicited in mouse with human immunoglobulin repertoire.
Plos Pathog., 18, 2022
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7UYL
 | | 850 Fab | | 分子名称: | 850 Fab Heavy Chain, 850 Fab Light Chain, GLYCEROL, ... | | 著者 | Kucharska, I, Prieto, K, Julien, J.P. | | 登録日 | 2022-05-06 | | 公開日 | 2022-11-23 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | High-density binding to Plasmodium falciparum circumsporozoite protein repeats by inhibitory antibody elicited in mouse with human immunoglobulin repertoire.
Plos Pathog., 18, 2022
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3BM3
 | | Restriction endonuclease PspGI-substrate DNA complex | | 分子名称: | CITRIC ACID, DNA (5'-D(*CP*AP*TP*CP*CP*AP*GP*GP*TP*AP*C)-3'), DNA (5'-D(*GP*GP*TP*AP*CP*CP*TP*GP*GP*AP*T)-3'), ... | | 著者 | Szczepanowski, R.H, Carpenter, M, Czapinska, H, Tamulaitis, G, Siksnys, V, Bhagwat, A, Bochtler, M. | | 登録日 | 2007-12-12 | | 公開日 | 2008-09-16 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | A direct crystallographic demonstration that Type II restriction endonuclease PspGI flips nucleotides
To be Published
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6UUD
 | | Crystal structure of antibody 5D5 in complex with PfCSP N-terminal peptide | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 5D5 Antibody Fab, ... | | 著者 | Thai, E, Scally, S.W, Julien, J.P. | | 登録日 | 2019-10-30 | | 公開日 | 2020-07-15 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | A high-affinity antibody against the CSP N-terminal domain lacks Plasmodium falciparum inhibitory activity.
J.Exp.Med., 217, 2020
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1MLN
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