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8Y8A
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BU of 8y8a by Molmil
Structure of HCoV-HKU1C spike in the functionally anchored-3up conformation with 3TMPRSS2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
著者Lu, Y.C, Zhang, X, Wang, H.F, Liu, X.C, Sun, L, Yang, H.T.
登録日2024-02-06
公開日2024-07-17
実験手法ELECTRON MICROSCOPY (3.19 Å)
主引用文献TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry.
Cell, 2024
8Y8B
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BU of 8y8b by Molmil
Local structure of HCoV-HKU1C spike in complex with TMPRSS2 and glycan
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
著者Wang, H.F, Zhang, X, Lu, Y.C, Liu, X.C, Sun, L, Yang, H.T.
登録日2024-02-06
公開日2024-07-17
実験手法ELECTRON MICROSCOPY (3.01 Å)
主引用文献TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry.
Cell, 2024
8Y8F
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BU of 8y8f by Molmil
Structure of HCoV-HKU1C spike in the glycan-activated-closed conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
著者Lu, Y.C, Zhang, X, Wang, H.F, Sun, L, Yang, H.T.
登録日2024-02-06
公開日2024-07-17
実験手法ELECTRON MICROSCOPY (3.07 Å)
主引用文献TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry.
Cell, 2024
8Y8J
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BU of 8y8j by Molmil
Local structure of HCoV-HKU1C spike in complex with glycan
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
著者Lu, Y.C, Zhang, X, Wang, H.F, Sun, L, Yang, H.T.
登録日2024-02-06
公開日2024-07-17
実験手法ELECTRON MICROSCOPY (3.57 Å)
主引用文献TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry.
Cell, 2024
6EYQ
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BU of 6eyq by Molmil
Crystal structure of a mutated OpuBC in complex with choline
分子名称: CHOLINE ION, Choline-binding protein
著者Peherstorfer, S, Teichmann, L, Smits, S.H, Schmitt, L, Bremer, E.
登録日2017-11-13
公開日2018-11-21
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structure of a mutated OpuBC in complex with choline
To Be Published
8Y8D
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BU of 8y8d by Molmil
Structure of HCoV-HKU1C spike in the inactive-1up conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
著者Lu, Y.C, Zhang, X, Wang, H.F, Sun, L, Yang, H.T.
登録日2024-02-06
公開日2024-07-17
実験手法ELECTRON MICROSCOPY (3.41 Å)
主引用文献TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry.
Cell, 2024
8Y8G
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BU of 8y8g by Molmil
Structure of HCoV-HKU1C spike in the glycan-activated-1up conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
著者Lu, Y.C, Zhang, X, Wang, H.F, Sun, L, Yang, H.T.
登録日2024-02-06
公開日2024-07-17
実験手法ELECTRON MICROSCOPY (3.23 Å)
主引用文献TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry.
Cell, 2024
6EYH
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BU of 6eyh by Molmil
Structure of a OpuBC mutant with bound Glycine betaine
分子名称: 3-(dimethyl-lambda~4~-sulfanyl)propanoic acid, Choline binding protein OpuBC
著者Peherstorfer, S, Teichmann, L, Smits, S.H, Schmitt, L, Bremer, E.
登録日2017-11-13
公開日2018-11-21
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structure of a OpuBC mutant with bound DMSP
To Be Published
4L4T
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BU of 4l4t by Molmil
Structure of human MAIT TCR in complex with human MR1-6-FP
分子名称: 2-amino-4-oxo-3,4-dihydropteridine-6-carbaldehyde, Beta-2-microglobulin, MAIT T-cell receptor alpha chain, ...
著者Patel, O, Kjer-Nielsen, L, Le Nours, J, Eckle, S.B.G, Birkinshaw, R.W, Beddoe, T, Corbett, A.J, Liu, L, Miles, J.J, Meehan, B, Reantragoon, R, Sandoval-Romero, M.L, Sullivan, L.C, Brooks, A.G, Chen, Z, Fairlie, D.P, McCluskey, J, Rossjohn, J.
登録日2013-06-09
公開日2013-07-17
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Recognition of vitamin B metabolites by mucosal-associated invariant T cells.
Nat Commun, 4, 2013
8T2I
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BU of 8t2i by Molmil
Negative stain EM assembly of MYC, JAZ, and NINJA complex
分子名称: AFP homolog 2, Maltose/maltodextrin-binding periplasmic protein, Protein TIFY 10A, ...
著者Zhou, X.E, Zhang, Y, Zhou, Y, He, Q, Cao, X, Kariapper, L, Suino-Powell, K, Zhu, Y, Zhang, F, Karsten, M.
登録日2023-06-06
公開日2023-06-28
最終更新日2023-11-22
実験手法ELECTRON MICROSCOPY (10.4 Å)
主引用文献Assembly of JAZ-JAZ and JAZ-NINJA complexes in jasmonate signaling.
Plant Commun., 4, 2023
5GON
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BU of 5gon by Molmil
Structures of a beta-lactam bridged analogue in complex with tubulin
分子名称: (3R,4R)-4-(4-methoxy-3-oxidanyl-phenyl)-3-methyl-1-(3,4,5-trimethoxyphenyl)azetidin-2-one, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ...
著者Zhou, L, Liu, Y, Cheng, L, Wang, Y.
登録日2016-07-28
公開日2017-03-22
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献Potent Antitumor Activities and Structure Basis of the Chiral beta-Lactam Bridged Analogue of Combretastatin A-4 Binding to Tubulin.
J. Med. Chem., 59, 2016
8STG
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BU of 8stg by Molmil
Discovery and clinical validation of RLY-4008, the first highly selective FGFR2 inhibitor with activity across FGFR2 alterations and resistance mutations
分子名称: Fibroblast growth factor receptor 2, N-{4-[(5P)-4-amino-5-{3-fluoro-4-[(4-methylpyrimidin-2-yl)oxy]phenyl}-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-6-yl]phenyl}-2-methylpropanamide
著者Valverde, R, Foster, L.
登録日2023-05-10
公開日2023-06-07
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.79 Å)
主引用文献RLY-4008, the First Highly Selective FGFR2 Inhibitor with Activity across FGFR2 Alterations and Resistance Mutations.
Cancer Discov, 13, 2023
1TY4
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BU of 1ty4 by Molmil
Crystal structure of a CED-9/EGL-1 complex
分子名称: Apoptosis regulator ced-9, EGg Laying defective EGL-1, programmed cell death activator
著者Yan, N, Gu, L, Kokel, D, Xue, D, Shi, Y.
登録日2004-07-07
公開日2004-09-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural, Biochemical, and Functional Analyses of CED-9 Recognition by the Proapoptotic Proteins EGL-1 and CED-4
Mol.Cell, 15, 2004
7OIH
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BU of 7oih by Molmil
Glycosylation in the crystal structure of neutrophil myeloperoxidase
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Krawczyk, L, Semwal, S, Bouckaert, J.
登録日2021-05-11
公開日2022-08-24
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.603 Å)
主引用文献Native glycosylation and binding of the antidepressant paroxetine in a low-resolution crystal structure of human myeloperoxidase.
Acta Crystallogr D Struct Biol, 78, 2022
1RUV
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BU of 1ruv by Molmil
RIBONUCLEASE A-URIDINE VANADATE COMPLEX: HIGH RESOLUTION RESOLUTION X-RAY STRUCTURE (1.3 A)
分子名称: RIBONUCLEASE A, TERTIARY-BUTYL ALCOHOL, URIDINE-2',3'-VANADATE
著者Ladner, J.E, Wladkowski, B, Svensson, L.A, Sjolin, L, Gilliland, G.L.
登録日1995-07-27
公開日1997-04-01
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献X-ray structure of a ribonuclease A-uridine vanadate complex at 1.3 A resolution.
Acta Crystallogr.,Sect.D, 53, 1997
8GDV
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BU of 8gdv by Molmil
Structure of M66I mutant of disulfide stabilized HIV-1 CA hexamer in complex with CPSF6 peptide and IP6
分子名称: Cleavage and polyadenylation specificity factor subunit 6, Gag polyprotein, INOSITOL HEXAKISPHOSPHATE
著者Briganti, L, Schope, L, Kvaratskhelia, M.
登録日2023-03-06
公開日2024-03-13
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structure of M66I mutant of disulfide stabilized HIV-1 CA hexamer in complex with CPSF6 peptide and IP6
To Be Published
7NS1
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BU of 7ns1 by Molmil
S. aureus pepG1 NMR solution structure
分子名称: Snterotoxin A
著者Nonin-Lecomte, S, fermon, L, Felden, B, Pinel-Marie, M.L.
登録日2021-03-05
公開日2021-07-21
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Bacterial Type I Toxins: Folding and Membrane Interactions.
Toxins, 13, 2021
6FHN
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BU of 6fhn by Molmil
Structural dynamics and catalytic properties of a multi-modular xanthanase (Pt derivative)
分子名称: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, CHLORIDE ION, ...
著者Moroz, O.V, Jensen, P.F, McDonald, S.P, McGregor, N, Blagova, E, Comamala, G, Segura, D.R, Anderson, L, Vasu, S.M, Rao, V.P, Giger, L, Monrad, R.N, Svendsen, A, Nielsen, J.E, Henrissat, B, Davies, G.J, Brumer, H, Rand, K, Wilson, K.S.
登録日2018-01-15
公開日2018-08-29
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Dynamics and Catalytic Properties of a Multimodular Xanthanase
Acs Catalysis, 2018
4L4V
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BU of 4l4v by Molmil
Structure of human MAIT TCR in complex with human MR1-RL-6-Me-7-OH
分子名称: 1-deoxy-1-(7-hydroxy-6-methyl-2,4-dioxo-3,4-dihydropteridin-8(2H)-yl)-D-ribitol, Beta-2-microglobulin, GLYCEROL, ...
著者Patel, O, Kjer-Nielsen, L, Le Nours, J, Eckle, S.B.G, Birkinshaw, R.W, Beddoe, T, Corbett, A.J, Liu, L, Miles, J.J, Meehan, B, Reantragoon, R, Sandoval-Romero, M.L, Sullivan, L.C, Brooks, A.G, Chen, Z, Fairlie, D.P, McCluskey, J, Rossjohn, J.
登録日2013-06-09
公開日2013-07-17
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Recognition of vitamin B metabolites by mucosal-associated invariant T cells.
Nat Commun, 4, 2013
3ZCU
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BU of 3zcu by Molmil
Rabbit muscle glycogen phosphorylase b in complex with N-(pyridyl-2- carbonyl)-N-beta-D-glucopyranosyl urea determined at 2.05 A resolution
分子名称: GLYCOGEN PHOSPHORYLASE, MUSCLE FORM, N-[(pyridin-2-ylcarbonyl)carbamoyl]-beta-D-glucopyranosylamine, ...
著者Chrysina, E.D, Nagy, V, Felfoldi, N, Konya, B, Telepo, K, Praly, J.P, Docsa, T, Gergely, P, Alexacou, K.M, Hayes, J.M, Konstantakaki, M, Kardakaris, R, Leonidas, D.D, Zographos, S.E, Oikonomakos, N.G, Somsak, L.
登録日2012-11-21
公開日2013-12-11
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Synthesis, Kinetic, Computational and Crystallographic Evaluation of N-Acyl-N-Beta-D- Glucopyranosyl)Ureas, Nanomolar Glucose Analogue Inhibitors of Glycogen Phosphorylase, Potential Antidiabetic Agents
To be Published
8K37
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BU of 8k37 by Molmil
Structure of the bacteriophage lambda neck
分子名称: Head-tail connector protein FII, Tail tube protein, Tail tube terminator protein
著者Xiao, H, Tan, L, Cheng, L.P, Liu, H.R.
登録日2023-07-14
公開日2023-11-15
最終更新日2024-01-17
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structure of the siphophage neck-Tail complex suggests that conserved tail tip proteins facilitate receptor binding and tail assembly.
Plos Biol., 21, 2023
8K38
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BU of 8k38 by Molmil
The structure of bacteriophage lambda portal-adaptor
分子名称: Head completion protein, Portal protein B
著者Xiao, H, Tan, L, Cheng, L.P, Liu, H.R.
登録日2023-07-14
公開日2023-11-15
最終更新日2024-01-17
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structure of the siphophage neck-Tail complex suggests that conserved tail tip proteins facilitate receptor binding and tail assembly.
Plos Biol., 21, 2023
8K39
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BU of 8k39 by Molmil
Structure of the bacteriophage lambda portal vertex
分子名称: Major capsid protein, Portal protein B
著者Xiao, H, Tan, L, Cheng, L.P, Liu, H.R.
登録日2023-07-14
公開日2023-11-15
最終更新日2024-01-17
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structure of the siphophage neck-Tail complex suggests that conserved tail tip proteins facilitate receptor binding and tail assembly.
Plos Biol., 21, 2023
8K36
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BU of 8k36 by Molmil
Structure of the bacteriophage lambda tail tube
分子名称: Tail tube protein
著者Xiao, H, Tan, L, Cheng, L.P, Liu, H.R.
登録日2023-07-14
公開日2023-11-15
最終更新日2024-01-17
実験手法ELECTRON MICROSCOPY (3.48 Å)
主引用文献Structure of the siphophage neck-Tail complex suggests that conserved tail tip proteins facilitate receptor binding and tail assembly.
Plos Biol., 21, 2023
6FWZ
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BU of 6fwz by Molmil
Crystal structure of human UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase (DPAGT1) (V264G mutant) in complex with UDP-GlcNAc
分子名称: (2S)-3-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-[(6E)-HEXADEC-6-ENOYLOXY]PROPYL (8E)-OCTADEC-8-ENOATE, MAGNESIUM ION, UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase, ...
著者Pike, A.C.W, Dong, Y.Y, Chu, A, Tessitore, A, Goubin, S, Dong, L, Mukhopadhyay, S, Mahajan, P, Chalk, R, Berridge, G, Wang, D, Kupinska, K, Belaya, K, Beeson, D, Burgess-Brown, N, Edwards, A.M, Arrowsmith, C.H, Bountra, C, Carpenter, E.P, Structural Genomics Consortium (SGC)
登録日2018-03-07
公開日2018-07-25
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structures of DPAGT1 Explain Glycosylation Disease Mechanisms and Advance TB Antibiotic Design.
Cell, 175, 2018

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