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2FDB
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Crystal Structure of Fibroblast growth factor (FGF)8b in complex with FGF Receptor (FGFR) 2c
分子名称: Fibroblast growth factor receptor 2, fibroblast growth factor 8 isoform B
著者Mohammadi, M, Olsen, S.K.
登録日2005-12-13
公開日2006-02-07
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Structural basis by which alternative splicing modulates the organizer activity of FGF8 in the brain
Genes Dev., 20, 2006
2HYU
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BU of 2hyu by Molmil
Human Annexin A2 with heparin tetrasaccharide bound
分子名称: 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, Annexin A2, CALCIUM ION
著者Shao, C, Head, J.F, Seaton, B.A.
登録日2006-08-07
公開日2006-09-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Crystallographic Analysis of Calcium-dependent Heparin Binding to Annexin A2.
J.Biol.Chem., 281, 2006
2HYW
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Human Annexin A2 with Calcium bound
分子名称: Annexin A2, CALCIUM ION
著者Shao, C, Head, J.F, Seaton, B.A.
登録日2006-08-07
公開日2006-09-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystallographic Analysis of Calcium-dependent Heparin Binding to Annexin A2.
J.Biol.Chem., 281, 2006
2HYV
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Human Annexin A2 with heparin hexasaccharide bound
分子名称: 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid, Annexin A2, CALCIUM ION
著者Shao, C, Head, J.F, Seaton, B.A.
登録日2006-08-07
公開日2006-09-05
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献Crystallographic analysis of calcium-dependent heparin binding to annexin A2.
J.Biol.Chem., 281, 2006
7WSO
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BU of 7wso by Molmil
Structure of a membrane protein G
分子名称: B-cell antigen receptor complex-associated protein alpha chain, B-cell antigen receptor complex-associated protein beta chain, Immunoglobulin heavy constant gamma 1
著者Ma, X, Zhu, Y, Chen, Y, Huang, Z.
登録日2022-01-30
公開日2022-08-31
実験手法ELECTRON MICROSCOPY (3.03 Å)
主引用文献Cryo-EM structures of two human B cell receptor isotypes.
Science, 377, 2022
5HXG
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STM1697-FlhD complex
分子名称: Flagellar transcriptional regulator FlhD, Uncharacterized protein STM1697
著者Li, B, Yuan, Z, Qin, L, Gu, L.
登録日2016-01-30
公開日2017-02-15
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.998 Å)
主引用文献Crystal structure of STM1697-FlhD complex
To Be Published
5IO1
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BU of 5io1 by Molmil
CRYSTAL STRUCTURE OF RECOMBINANT HUMAN Z ALPHA-1-ANTITRYPSIN
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-1-antitrypsin
著者Zhou, A.
登録日2016-03-08
公開日2016-06-08
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (3.34 Å)
主引用文献Molecular Mechanism of Z alpha 1-Antitrypsin Deficiency
J. Biol. Chem., 291, 2016
2P39
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Crystal structure of human FGF23
分子名称: 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose, Fibroblast growth factor 23
著者Mohammadi, M.
登録日2007-03-08
公開日2007-04-10
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Molecular insights into the klotho-dependent, endocrine mode of action of fibroblast growth factor 19 subfamily members.
Mol.Cell.Biol., 27, 2007
2P23
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Crystal structure of human FGF19
分子名称: Fibroblast growth factor 19
著者Mohammadi, M.
登録日2007-03-06
公開日2007-04-10
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Molecular insights into the klotho-dependent, endocrine mode of action of fibroblast growth factor 19 subfamily members.
Mol.Cell.Biol., 27, 2007
7U23
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BU of 7u23 by Molmil
Single-chain LCDV-1 viral insulin-like peptide bound to IGF-1R ectodomain, leucine-zippered form
分子名称: Insulin-like growth factor 1 receptor, single-chain LCDV-1 viral insulin-like peptide
著者Kirk, N.S, Lawrence, M.C.
登録日2022-02-22
公開日2022-11-16
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Interaction of a viral insulin-like peptide with the IGF-1 receptor produces a natural antagonist.
Nat Commun, 13, 2022
3UG9
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BU of 3ug9 by Molmil
Crystal Structure of the Closed State of Channelrhodopsin
分子名称: Archaeal-type opsin 1, Archaeal-type opsin 2, OLEIC ACID, ...
著者Kato, H.E, Ishitani, R, Nureki, O.
登録日2011-11-02
公開日2012-01-25
最終更新日2017-08-09
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the channelrhodopsin light-gated cation channel
Nature, 482, 2012
6RPJ
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A Non-blocking anti-CTLA-4 Nanobody complexed with CTLA-4
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, A non-blocking CTLA-4 nanobody, Cytotoxic T-lymphocyte protein 4, ...
著者Gao, H, Zhou, A, Zhang, F.
登録日2019-05-14
公開日2020-07-08
最終更新日2020-11-11
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献A Non-blocking anti-CTLA-4 Nanobody complexed with CTLA-4
To Be Published
7FJD
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Cryo-EM structure of a membrane protein(WT)
分子名称: CHOLESTEROL, T cell receptor alpha variable 12-3,Possible J 11 gene segment,T cell receptor alpha chain constant, T cell receptor beta variable 6-5,M1-specific T cell receptor beta chain,T cell receptor beta constant 2, ...
著者Chen, Y, Zhu, Y, Gao, W, Zhang, A, Guo, C, Huang, Z.
登録日2021-08-03
公開日2022-07-27
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Cholesterol inhibits TCR signaling by directly restricting TCR-CD3 core tunnel motility.
Mol.Cell, 82, 2022
7FJE
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Cryo-EM structure of a membrane protein(LL)
分子名称: CHOLESTEROL, T cell receptor alpha variable 12-3,Possible J 11 gene segment,T cell receptor alpha chain constant, T cell receptor beta variable 6-5,M1-specific T cell receptor beta chain,T cell receptor beta constant 2, ...
著者Chen, Y, Zhu, Y, Gao, W, Zhang, A, Guo, C, Huang, Z.
登録日2021-08-03
公開日2022-07-27
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Cholesterol inhibits TCR signaling by directly restricting TCR-CD3 core tunnel motility.
Mol.Cell, 82, 2022
7FJF
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Cryo-EM structure of a membrane protein(CS)
分子名称: CHOLEST-5-EN-3-YL HYDROGEN SULFATE, T cell receptor alpha variable 12-3,Possible J 11 gene segment,T cell receptor alpha chain constant, T cell receptor beta variable 6-5,M1-specific T cell receptor beta chain,T cell receptor beta constant 2, ...
著者Chen, Y, Zhu, Y, Gao, W, Zhang, A, Guo, C, Huang, Z.
登録日2021-08-03
公開日2022-07-27
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Cholesterol inhibits TCR signaling by directly restricting TCR-CD3 core tunnel motility.
Mol.Cell, 82, 2022
7CYB
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Saimiri boliviensis boliviensis galectin-13 with glycerol
分子名称: GLYCEROL, Galectin
著者Su, J.
登録日2020-09-03
公開日2021-06-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Actin binding to galectin-13/placental protein-13 occurs independently of the galectin canonical ligand-binding site.
Glycobiology, 31, 2021
7CYA
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Saimiri boliviensis boliviensis galectin-13 with lactose
分子名称: Galectin, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose
著者Su, J.
登録日2020-09-03
公開日2021-06-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献Actin binding to galectin-13/placental protein-13 occurs independently of the galectin canonical ligand-binding site.
Glycobiology, 31, 2021
7E24
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Crystal structure of SDR family NAD(P)-dependent oxidoreductase from Exiguobacterium
分子名称: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Oxidoreductase
著者Chen, L, Tang, J, Yuan, S.
登録日2021-02-04
公開日2021-09-29
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.7203 Å)
主引用文献Structure-guided evolution of a ketoreductase forefficient and stereoselective bioreduction of bulkyalpha-aminobeta-keto esters
Catalysis Science And Technology, 2021
7E28
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Crystal structure of SDR family NAD(P)-dependent oxidoreductase from Exiguobacterium
分子名称: Oxidoreductase
著者Chen, L, Tang, J, Yuan, S.
登録日2021-02-05
公開日2021-09-29
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Structure-guided evolution of a ketoreductase forefficient and stereoselective bioreduction of bulkyalpha-aminobeta-keto esters
Catalysis Science And Technology, 2021
7EEI
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Structure of Rift Valley fever virus RNA-dependent RNA polymerase
分子名称: Replicase
著者Wang, X, Hu, C.X.
登録日2021-03-18
公開日2021-11-17
最終更新日2022-03-16
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structure of Rift Valley Fever Virus RNA-Dependent RNA Polymerase.
J.Virol., 96, 2022
8WUT
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SpCas9-MMLV RT-pegRNA-target DNA complex (initiation)
分子名称: CRISPR-associated endonuclease Cas9/Csn1, DNA (5'-D(*TP*GP*AP*TP*GP*GP*CP*AP*GP*AP*GP*TP*AP*CP*TP*AP*G)-3'), DNA (51-MER), ...
著者Shuto, Y, Nakagawa, R, Hoki, M, Omura, S.N, Hirano, H, Itoh, Y, Nureki, O.
登録日2023-10-21
公開日2024-06-05
最終更新日2024-09-11
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural basis for pegRNA-guided reverse transcription by a prime editor.
Nature, 631, 2024
8WUS
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SpCas9-MMLV RT-pegRNA-target DNA complex (termination)
分子名称: CRISPR-associated endonuclease Cas9/Csn1, DNA (40-MER), DNA (5'-D(*TP*GP*AP*TP*GP*GP*CP*AP*GP*AP*GP*TP*AP*CP*TP*AP*G)-3'), ...
著者Shuto, Y, Nakagawa, R, Hoki, M, Omura, S.N, Hirano, H, Itoh, Y, Nureki, O.
登録日2023-10-21
公開日2024-06-05
最終更新日2024-09-11
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural basis for pegRNA-guided reverse transcription by a prime editor.
Nature, 631, 2024
8WUV
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SpCas9-MMLV RT-pegRNA-target DNA complex (elongation 16-nt)
分子名称: CRISPR-associated endonuclease Cas9/Csn1, DNA (5'-D(*TP*GP*AP*TP*GP*GP*CP*AP*GP*AP*GP*TP*AP*CP*TP*AP*G)-3'), DNA (50-MER), ...
著者Shuto, Y, Nakagawa, R, Hoki, M, Omura, S.N, Hirano, H, Itoh, Y, Nureki, O.
登録日2023-10-21
公開日2024-06-05
最終更新日2024-09-11
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural basis for pegRNA-guided reverse transcription by a prime editor.
Nature, 631, 2024
8WUU
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SpCas9-pegRNA-target DNA complex (pre-initiation)
分子名称: CRISPR-associated endonuclease Cas9/Csn1, DNA (34-MER), DNA (5'-D(*TP*GP*AP*TP*GP*GP*CP*AP*GP*AP*GP*TP*AP*CP*TP*AP*G)-3'), ...
著者Shuto, Y, Nakagawa, R, Hoki, M, Omura, S.N, Hirano, H, Itoh, Y, Nureki, O.
登録日2023-10-21
公開日2024-06-05
最終更新日2024-09-11
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural basis for pegRNA-guided reverse transcription by a prime editor.
Nature, 631, 2024
7CN2
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Subparticle refinement of human papillomavirus type 16 pesudovirus in complex with H16.001 Fab
分子名称: Major capsid protein L1, The heavy chain variable region of H16.001 Fab fragment, The light chain variable region of H16.001 Fab fragment
著者He, M.Z, Li, S.W.
登録日2020-07-29
公開日2020-09-02
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.43 Å)
主引用文献Structural characterization of a neutralizing mAb H16.001, a potent candidate for a common potency assay for various HPV16 VLPs.
Npj Vaccines, 5, 2020

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