4R82
| Streptomyces globisporus C-1027 NADH:FAD oxidoreductase SgcE6 in complex with NAD and FAD fragments | 分子名称: | ACETATE ION, CALCIUM ION, CHLORIDE ION, ... | 著者 | Tan, K, Bigelow, L, Clancy, S, Babnigg, G, Bingman, C.A, Yennamalli, R, Lohman, J.R, Ma, M, Shen, B, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | 登録日 | 2014-08-29 | 公開日 | 2014-10-01 | 最終更新日 | 2016-11-02 | 実験手法 | X-RAY DIFFRACTION (1.659 Å) | 主引用文献 | Crystal Structures of SgcE6 and SgcC, the Two-Component Monooxygenase That Catalyzes Hydroxylation of a Carrier Protein-Tethered Substrate during the Biosynthesis of the Enediyne Antitumor Antibiotic C-1027 in Streptomyces globisporus. Biochemistry, 55, 2016
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3M9A
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3MKZ
| Structure of SopB(155-272)-18mer complex, P21 form | 分子名称: | CALCIUM ION, DNA (5'-D(*CP*TP*GP*GP*GP*AP*CP*CP*AP*TP*GP*GP*TP*CP*CP*CP*AP*G)-3'), Protein sopB | 著者 | Schumacher, M.A. | 登録日 | 2010-04-15 | 公開日 | 2010-05-05 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.98 Å) | 主引用文献 | Insight into F plasmid DNA segregation revealed by structures of SopB and SopB-DNA complexes. Nucleic Acids Res., 38, 2010
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3M8F
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3M8K
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3O52
| Structure of the E.coli GDP-mannose hydrolase (yffh) in complex with tartrate | 分子名称: | CHLORIDE ION, D(-)-TARTARIC ACID, GDP-mannose pyrophosphatase nudK, ... | 著者 | Amzel, L.M, Gabelli, S.B, Boto, A.N. | 登録日 | 2010-07-27 | 公開日 | 2011-05-11 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural studies of the Nudix GDP-mannose hydrolase from E. coli reveals a new motif for mannose recognition. Proteins, 79, 2011
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2GL7
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3Q4I
| Crystal structure of CDP-Chase in complex with Gd3+ | 分子名称: | GADOLINIUM ION, Phosphohydrolase (MutT/nudix family protein) | 著者 | Duong-Ly, K.C, Gabelli, S.B, Amzel, L.M. | 登録日 | 2010-12-23 | 公開日 | 2011-07-13 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | The Nudix Hydrolase CDP-Chase, a CDP-Choline Pyrophosphatase, Is an Asymmetric Dimer with Two Distinct Enzymatic Activities. J.Bacteriol., 193, 2011
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2O1C
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2O5W
| Structure of the E. coli dihydroneopterin triphosphate pyrophosphohydrolase in complex with Sm+3 and pyrophosphate | 分子名称: | PYROPHOSPHATE, SAMARIUM (III) ION, SODIUM ION, ... | 著者 | Gabelli, S.B, Bianchet, M.A, Amzel, L.M. | 登録日 | 2006-12-06 | 公開日 | 2007-08-28 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structure and function of the E. coli dihydroneopterin triphosphate pyrophosphatase: a Nudix enzyme involved in folate biosynthesis. Structure, 15, 2007
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2O6X
| Crystal Structure of ProCathepsin L1 from Fasciola hepatica | 分子名称: | Secreted cathepsin L 1 | 著者 | Brinen, L.S, Dalton, J.P, Geiger, S, Marion, R, Stack, C.M. | 登録日 | 2006-12-08 | 公開日 | 2007-12-18 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Structural and functional relationships in the virulence-associated cathepsin L proteases of the parasitic liver fluke, Fasciola hepatica. J.Biol.Chem., 283, 2008
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9C0C
| E.coli GroEL apoenzyme | 分子名称: | 60 kDa chaperonin | 著者 | Watson, E.R, Lander, G.C. | 登録日 | 2024-05-25 | 公開日 | 2024-08-07 | 最終更新日 | 2024-08-14 | 実験手法 | ELECTRON MICROSCOPY (3.41 Å) | 主引用文献 | Bis-sulfonamido-2-phenylbenzoxazoles Validate the GroES/EL Chaperone System as a Viable Antibiotic Target. J.Am.Chem.Soc., 146, 2024
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9C0D
| E.Faecium GroEL | 分子名称: | Chaperonin GroEL | 著者 | Watson, E.R, Lander, G.C. | 登録日 | 2024-05-25 | 公開日 | 2024-08-07 | 最終更新日 | 2024-08-14 | 実験手法 | ELECTRON MICROSCOPY (3.97 Å) | 主引用文献 | Bis-sulfonamido-2-phenylbenzoxazoles Validate the GroES/EL Chaperone System as a Viable Antibiotic Target. J.Am.Chem.Soc., 146, 2024
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3Q1P
| Crystal structure of CDP-Chase | 分子名称: | Phosphohydrolase (MutT/nudix family protein), SULFATE ION | 著者 | Duong-Ly, K.C, Gabelli, S.B, Amzel, L.M. | 登録日 | 2010-12-17 | 公開日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The Nudix Hydrolase CDP-Chase, a CDP-Choline Pyrophosphatase, Is an Asymmetric Dimer with Two Distinct Enzymatic Activities. J.Bacteriol., 193, 2011
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9C0B
| E.coli GroEL + PBZ1587 inhibitor | 分子名称: | 60 kDa chaperonin, N-(2-{4-[4-(aminomethyl)benzene-1-sulfonamido]phenyl}-1,3-benzoxazol-5-yl)-5-chlorothiophene-2-sulfonamide | 著者 | Watson, E.R, Lander, G.C. | 登録日 | 2024-05-25 | 公開日 | 2024-08-07 | 最終更新日 | 2024-08-14 | 実験手法 | ELECTRON MICROSCOPY (3.26 Å) | 主引用文献 | Bis-sulfonamido-2-phenylbenzoxazoles Validate the GroES/EL Chaperone System as a Viable Antibiotic Target. J.Am.Chem.Soc., 146, 2024
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7K8F
| Beta-lactamase mixed with Ceftriaxone, 10ms | 分子名称: | Beta-lactamase, Ceftriaxone, PHOSPHATE ION | 著者 | Pandey, S, Schmidt, M. | 登録日 | 2020-09-26 | 公開日 | 2021-09-22 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.60003138 Å) | 主引用文献 | Observation of substrate diffusion and ligand binding in enzyme crystals using high-repetition-rate mix-and-inject serial crystallography Iucrj, 8, 2021
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7K8H
| Beta-lactamase mixed with Ceftriaxone, 50ms | 分子名称: | Beta-lactamase, Ceftriaxone, PHOSPHATE ION | 著者 | Pandey, S, Schmidt, M. | 登録日 | 2020-09-27 | 公開日 | 2021-09-22 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.60006261 Å) | 主引用文献 | Observation of substrate diffusion and ligand binding in enzyme crystals using high-repetition-rate mix-and-inject serial crystallography Iucrj, 8, 2021
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7K8K
| Beta-lactamase mixed with Sulbactam, 60ms | 分子名称: | Beta-lactamase, PHOSPHATE ION, SULBACTAM, ... | 著者 | Pandey, S, Schmidt, M. | 登録日 | 2020-09-27 | 公開日 | 2021-09-22 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Observation of substrate diffusion and ligand binding in enzyme crystals using high-repetition-rate mix-and-inject serial crystallography Iucrj, 8, 2021
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7K8L
| Beta-lactamase, Unmixed | 分子名称: | Beta-lactamase, PHOSPHATE ION | 著者 | Pandey, S, Schmidt, M. | 登録日 | 2020-09-27 | 公開日 | 2021-09-22 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.8000102 Å) | 主引用文献 | Observation of substrate diffusion and ligand binding in enzyme crystals using high-repetition-rate mix-and-inject serial crystallography Iucrj, 8, 2021
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7K8E
| Beta-lactamase mixed with Ceftriaxone, 5ms | 分子名称: | Beta-lactamase, Ceftriaxone, PHOSPHATE ION | 著者 | Pandey, S, Schmidt, M. | 登録日 | 2020-09-26 | 公開日 | 2021-09-22 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.40005636 Å) | 主引用文献 | Observation of substrate diffusion and ligand binding in enzyme crystals using high-repetition-rate mix-and-inject serial crystallography Iucrj, 8, 2021
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6LXT
| Structure of post fusion core of 2019-nCoV S2 subunit | 分子名称: | Spike protein S2, TETRAETHYLENE GLYCOL, ZINC ION | 著者 | Zhu, Y, Sun, F. | 登録日 | 2020-02-11 | 公開日 | 2020-02-26 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Inhibition of SARS-CoV-2 (previously 2019-nCoV) infection by a highly potent pan-coronavirus fusion inhibitor targeting its spike protein that harbors a high capacity to mediate membrane fusion. Cell Res., 30, 2020
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6M71
| SARS-Cov-2 RNA-dependent RNA polymerase in complex with cofactors | 分子名称: | Non-structural protein 7, Non-structural protein 8, RNA-directed RNA polymerase | 著者 | Gao, Y, Yan, L, Huang, Y, Liu, F, Cao, L, Wang, T, Wang, Q, Lou, Z, Rao, Z. | 登録日 | 2020-03-16 | 公開日 | 2020-04-01 | 最終更新日 | 2021-03-10 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structure of the RNA-dependent RNA polymerase from COVID-19 virus. Science, 368, 2020
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7XNA
| Crystal structure of somatostatin receptor 2 (SSTR2) with peptide antagonist CYN 154806 | 分子名称: | CYN 154806, Somatostatin receptor type 2,Endo-1,4-beta-xylanase | 著者 | Zhao, W, Han, S, Qiu, N, Feng, W, Lu, M, Yang, D, Wang, M.-W, Wu, B, Zhao, Q. | 登録日 | 2022-04-28 | 公開日 | 2022-08-03 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Structural insights into ligand recognition and selectivity of somatostatin receptors. Cell Res., 32, 2022
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7XMR
| CryoEM structure of the somatostatin receptor 2 (SSTR2) in complex with Gi1 and its endogeneous peptide ligand SST-14 | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | 著者 | Wenli, Z, Shuo, H, Na, Q, Wenbo, Z, Mengjie, L, Dehua, Y, Ming-Wei, W, Wu, B, Zhao, Q. | 登録日 | 2022-04-26 | 公開日 | 2022-08-03 | 最終更新日 | 2022-08-17 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural insights into ligand recognition and selectivity of somatostatin receptors. Cell Res., 32, 2022
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7XN9
| Crystal structure of SSTR2 and L-054,522 complex | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Somatostatin receptor type 2,Endo-1,4-beta-xylanase, tert-butyl (2S)-6-azanyl-2-[[(2R,3S)-3-(1H-indol-3-yl)-2-[[4-(2-oxidanylidene-3H-benzimidazol-1-yl)piperidin-1-yl]carbonylamino]butanoyl]amino]hexanoate | 著者 | Zhao, W, Han, S, Qiu, N, Feng, W, Lu, M, Yang, D, Wang, M.-W, Wu, B, Zhao, Q. | 登録日 | 2022-04-28 | 公開日 | 2022-08-03 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural insights into ligand recognition and selectivity of somatostatin receptors. Cell Res., 32, 2022
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