7K8H

Beta-lactamase mixed with Ceftriaxone, 50ms

Summary for 7K8H

• Entry DOI: 10.2210/pdb7k8h/pdb
• Descriptor: Beta-lactamase, PHOSPHATE ION, Ceftriaxone, ... (4 entities in total)
• Functional Keywords: beta-lactamase, antibiotic, hydrolase-antibiotic complex, structural protein
• Biological source: Mycobacterium tuberculosis
• Total number of polymer chains: 4
• Total formula weight: 116201.61

Authors

Pandey, S.,Schmidt, M. (deposition date: 2020-09-27, release date: 2021-09-22, Last modification date: 2023-10-18)

• Primary citation: Pandey, S.,Calvey, G.,Katz, A.M.,Malla, T.N.,Koua, F.H.M.,Martin-Garcia, J.M.,Poudyal, I.,Yang, J.H.,Vakili, M.,Yefanov, O.,Zielinski, K.A.,Bajt, S.,Awel, S.,Doerner, K.,Frank, M.,Gelisio, L.,Jernigan, R.,Kirkwood, H.,Kloos, M.,Koliyadu, J.,Mariani, V.,Miller, M.D.,Mills, G.,Nelson, G.,Olmos, J.L.J.,Sadri, A.,Sato, T.,Tolstikova, A.,Xu, W.,Ourmazd, A.,Spence, J.C.H.,Schwander, P.,Barty, A.,Chapman, H.N.,Fromme, P.,Mancuso, A.P.,Phillips, G.N.J.,Bean, R.,Pollack, L.,Schmidt, M.; Observation of substrate diffusion and ligand binding in enzyme crystals using high-repetition-rate mix-and-inject serial crystallography; Iucrj, 8:878-895, 2021; DOI: 10.1107/S2052252521008125

Experimental method

X-RAY DIFFRACTION (2.60006254355 Å)