4F8E
 
 | | Crystal structure of human PRS1 D52H mutant | | 分子名称: | MAGNESIUM ION, Ribose-phosphate pyrophosphokinase 1, SULFATE ION | | 著者 | Chen, P, Teng, M, Li, X. | | 登録日 | 2012-05-17 | | 公開日 | 2013-05-22 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | | 主引用文献 | A small disturbance, but a serious disease: the possible mechanism of D52H-mutant of human PRS1 that causes gout
Iubmb Life, 65, 2013
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6UM1
 | | Structure of M-6-P/IGFII Receptor at pH 4.5 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cation-independent mannose-6-phosphate receptor, ... | | 著者 | Wang, R, Qi, X, Li, X. | | 登録日 | 2019-10-08 | | 公開日 | 2020-02-26 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (3.46 Å) | | 主引用文献 | Marked structural rearrangement of mannose 6-phosphate/IGF2 receptor at different pH environments
Sci Adv, 6, 2020
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6UM2
 | | Structure of M-6-P/IGFII Receptor and IGFII complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Cation-independent mannose-6-phosphate receptor, Insulin-like growth factor II | | 著者 | Wang, R, Qi, X, Li, X. | | 登録日 | 2019-10-08 | | 公開日 | 2020-02-26 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (4.32 Å) | | 主引用文献 | Marked structural rearrangement of mannose 6-phosphate/IGF2 receptor at different pH environments
Sci Adv, 6, 2020
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4JEK
 | | Structure of dibenzothiophene monooxygenase (DszC) from Rhodococcus erythropolis | | 分子名称: | Dibenzothiophene desulfurization enzyme C | | 著者 | Zhang, L, Duan, X.L, Zhou, D.M, Li, X. | | 登録日 | 2013-02-27 | | 公開日 | 2013-09-18 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystallization and preliminary structural analysis of dibenzothiophene monooxygenase (DszC) from Rhodococcus erythropolis
Acta Crystallogr.,Sect.F, 69, 2013
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1QSR
 | | CRYSTAL STRUCTURE OF TETRAHYMENA GCN5 WITH BOUND ACETYL-COENZYME A | | 分子名称: | ACETYL COENZYME *A, TGCN5 HISTONE ACETYL TRANSFERASE | | 著者 | Rojas, J.R, Trievel, R.C, Zhou, J, Mo, Y, Li, X, Berger, S.L, David Allis, C, Marmorstein, R. | | 登録日 | 1999-06-23 | | 公開日 | 1999-09-08 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure of Tetrahymena GCN5 bound to coenzyme A and a histone H3 peptide.
Nature, 401, 1999
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1QST
 | | CRYSTAL STRUCTURE OF TETRAHYMENA GCN5 | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, TGCN5 HISTONE ACETYL TRANSFERASE | | 著者 | Rojas, J.R, Trievel, R.C, Zhou, J, Mo, Y, Li, X, Berger, S.L, David Allis, C, Marmorstein, R. | | 登録日 | 1999-06-23 | | 公開日 | 1999-09-08 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structure of Tetrahymena GCN5 bound to coenzyme A and a histone H3 peptide.
Nature, 401, 1999
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1QSN
 | | CRYSTAL STRUCTURE OF TETRAHYMENA GCN5 WITH BOUND COENZYME A AND HISTONE H3 PEPTIDE | | 分子名称: | COENZYME A, HISTONE H3, TGCN5 HISTONE ACETYL TRANSFERASE | | 著者 | Rojas, J.R, Trievel, R.C, Zhou, J, Mo, Y, Li, X, Berger, S.L, David Allis, C, Marmorstein, R. | | 登録日 | 1999-06-22 | | 公開日 | 1999-09-08 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure of Tetrahymena GCN5 bound to coenzyme A and a histone H3 peptide.
Nature, 401, 1999
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6J60
 | | hnRNP A1 reversible amyloid core GFGGNDNFG (residues 209-217) | | 分子名称: | 9-mer peptide (GFGGNDNFG) from Heterogeneous nuclear ribonucleoprotein A1 | | 著者 | Luo, F, Zhou, H, Gui, X, Li, D, Li, X, Liu, C. | | 登録日 | 2019-01-12 | | 公開日 | 2019-04-03 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON CRYSTALLOGRAPHY (0.96 Å) | | 主引用文献 | Structural basis for reversible amyloids of hnRNPA1 elucidates their role in stress granule assembly.
Nat Commun, 10, 2019
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8G05
 | | Cryo-EM structure of an orphan GPCR-Gi protein signaling complex | | 分子名称: | 6-(octylamino)pyrimidine-2,4(3H,5H)-dione, CHOLESTEROL, G-protein coupled receptor 84, ... | | 著者 | Zhang, X, Wang, Y.J, Li, X, Liu, G.B, Gong, W.M, Zhang, C. | | 登録日 | 2023-01-31 | | 公開日 | 2023-11-01 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Pro-phagocytic function and structural basis of GPR84 signaling.
Nat Commun, 14, 2023
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3T88
 | | Crystal structure of Escherichia coli MenB in complex with substrate analogue, OSB-NCoA | | 分子名称: | 1,4-Dihydroxy-2-naphthoyl-CoA synthase, CHLORIDE ION, GLYCEROL, ... | | 著者 | Li, H.-J, Li, X, Liu, N, Zhang, H, Truglio, J, Mishra, S, Kisker, C, Garcia-Diaz, M, Tonge, P. | | 登録日 | 2011-08-01 | | 公開日 | 2011-08-24 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.998 Å) | | 主引用文献 | Mechanism of the Intramolecular Claisen Condensation Reaction Catalyzed by MenB, a Crotonase Superfamily Member.
Biochemistry, 50, 2011
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3T8A
 | | Crystal structure of Mycobacterium tuberculosis MenB in complex with substrate analogue, OSB-NCoA | | 分子名称: | 1,4-Dihydroxy-2-naphthoyl-CoA synthase, o-succinylbenzoyl-N-coenzyme A | | 著者 | Li, H.-J, Li, X, Liu, N, Zhang, H, Truglio, J, Mishra, S, Kisker, C, Garcia-Diaz, M, Tonge, P. | | 登録日 | 2011-08-01 | | 公開日 | 2011-08-24 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.245 Å) | | 主引用文献 | Mechanism of the Intramolecular Claisen Condensation Reaction Catalyzed by MenB, a Crotonase Superfamily Member.
Biochemistry, 50, 2011
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1QXK
 | | Monoacid-Based, Cell Permeable, Selective Inhibitors of Protein Tyrosine Phosphatase 1B | | 分子名称: | 2-{4-[2-ACETYLAMINO-3-(4-CARBOXYMETHOXY-3-HYDROXY-PHENYL)-PROPIONYLAMINO]-BUTOXY}-6-HYDROXY-BENZOIC ACID METHYL ESTER, Protein-tyrosine phosphatase, non-receptor type 1 | | 著者 | Xin, Z, Liu, G, Abad-Zapatero, C, Pei, Z, Szczepankiewick, B.G, Li, X, Zhang, T, Hutchins, C.W, Hajduk, P.J, Ballaron, S.J, Stashko, M.A, Lubben, T.H, Trevillyan, J.M, Jirousek, M.R. | | 登録日 | 2003-09-08 | | 公開日 | 2003-10-28 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Identification of a Monoacid-Based, Cell Permeable, Selective
Inhibitor of Protein Tyrosine Phosphatase 1B
BIOORG.MED.CHEM.LETT., 13, 2003
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3T8B
 | | Crystal structure of Mycobacterium tuberculosis MenB with altered hexameric assembly | | 分子名称: | 1,4-Dihydroxy-2-naphthoyl-CoA synthase, GLYCEROL | | 著者 | Li, H.-J, Li, X, Liu, N, Zhang, H, Truglio, J, Mishra, S, Kisker, C, Garcia-Diaz, M, Tonge, P. | | 登録日 | 2011-08-01 | | 公開日 | 2011-08-24 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.649 Å) | | 主引用文献 | Mechanism of the Intramolecular Claisen Condensation Reaction Catalyzed by MenB, a Crotonase Superfamily Member.
Biochemistry, 50, 2011
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6UOX
 | | Structure of itraconazole-bound NPC1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(3-bromo-4-{4-[4-({(2R,4S)-2-(2,4-dichlorophenyl)-2-[(1H-1,2,4-triazol-1-yl)methyl]-1,3-dioxolan-4-yl}methoxy)phenyl]piperazin-1-yl}phenyl)-2-[(2S)-butan-2-yl]-2,4-dihydro-3H-1,2,4-triazol-3-one, ... | | 著者 | Long, T, Li, X. | | 登録日 | 2019-10-15 | | 公開日 | 2020-01-15 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (4.13 Å) | | 主引用文献 | Structural basis for itraconazole-mediated NPC1 inhibition.
Nat Commun, 11, 2020
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4Q77
 | | Crystal structure of Rot, a global regulator of virulence genes in Staphylococcus aureus | | 分子名称: | GLYCEROL, HTH-type transcriptional regulator rot | | 著者 | Zhu, Y, Fan, X, Li, X, Teng, M. | | 登録日 | 2014-04-24 | | 公開日 | 2014-09-17 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | | 主引用文献 | Structure of Rot, a global regulator of virulence genes in Staphylococcus aureus.
Acta Crystallogr.,Sect.D, 70, 2014
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3T89
 | | Crystal structure of Escherichia coli MenB, the 1,4-dihydroxy-2-naphthoyl-CoA synthase in vitamin K2 biosynthesis | | 分子名称: | 1,4-Dihydroxy-2-naphthoyl-CoA synthase, GLYCEROL, MALONATE ION | | 著者 | Li, H.-J, Li, X, Liu, N, Zhang, H, Truglio, J, Mishra, S, Kisker, C, Garcia-Diaz, M, Tonge, P. | | 登録日 | 2011-08-01 | | 公開日 | 2011-08-24 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.949 Å) | | 主引用文献 | Mechanism of the Intramolecular Claisen Condensation Reaction Catalyzed by MenB, a Crotonase Superfamily Member.
Biochemistry, 50, 2011
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4NXL
 | | Dibenzothiophene monooxygenase (DszC) from Rhodococcus erythropolis | | 分子名称: | DszC | | 著者 | Zhang, L, Duan, X, Li, X, Rao, Z. | | 登録日 | 2013-12-09 | | 公開日 | 2014-07-23 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural insights into the stabilization of active, tetrameric DszC by its C-terminus.
Proteins, 82, 2014
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5ZZ3
 | | Crystal structure of intracellular B30.2 domain of BTN3A3 | | 分子名称: | Butyrophilin, subfamily 3, member A3 isoform b variant | | 著者 | Yang, Y.Y, Li, X, Liu, W.D, Chen, C.C, Guo, R.T, Zhang, Y.H. | | 登録日 | 2018-05-30 | | 公開日 | 2019-04-03 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | A Structural Change in Butyrophilin upon Phosphoantigen Binding Underlies Phosphoantigen-Mediated V gamma 9V delta 2 T Cell Activation.
Immunity, 50, 2019
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1WDG
 | | crystal structure of MHV spike protein fusion core | | 分子名称: | E2 glycoprotein | | 著者 | Xu, Y, Liu, Y, Lou, Z, Qin, L, Li, X, Bai, Z, Tien, P, Gao, G.F, Rao, Z. | | 登録日 | 2004-05-14 | | 公開日 | 2004-06-15 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | | 主引用文献 | Structural Basis for Coronavirus-mediated Membrane Fusion: CRYSTAL STRUCTURE OF MOUSE HEPATITIS VIRUS SPIKE PROTEIN FUSION CORE
J.Biol.Chem., 279, 2004
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1WDF
 | | crystal structure of MHV spike protein fusion core | | 分子名称: | E2 glycoprotein | | 著者 | Xu, Y, Liu, Y, Lou, Z, Qin, L, Li, X, Bai, Z, Tien, P, Gao, G.F, Rao, Z. | | 登録日 | 2004-05-14 | | 公開日 | 2004-06-15 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural Basis for Coronavirus-mediated Membrane Fusion: CRYSTAL STRUCTURE OF MOUSE HEPATITIS VIRUS SPIKE PROTEIN FUSION CORE
J.Biol.Chem., 279, 2004
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4M0U
 | | crystal structure of human PRS1 Q133P mutant | | 分子名称: | Ribose-phosphate pyrophosphokinase 1, SULFATE ION | | 著者 | Chen, P, Teng, M, Li, X. | | 登録日 | 2013-08-02 | | 公開日 | 2015-02-04 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.74 Å) | | 主引用文献 | Crystal and EM Structures of Human Phosphoribosyl Pyrophosphate Synthase I (PRS1) Provide Novel Insights into the Disease-Associated Mutations
Plos One, 10, 2015
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8T05
 | | Structure of Ciona Myomaker bound to Fab1A1 | | 分子名称: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 1A1 Fab heavy chain, 1A1 Fab light chain, ... | | 著者 | Long, T, Li, X. | | 登録日 | 2023-05-31 | | 公開日 | 2023-09-27 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (3.22 Å) | | 主引用文献 | Cryo-EM structures of Myomaker reveal a molecular basis for myoblast fusion.
Nat.Struct.Mol.Biol., 30, 2023
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8T03
 | | Structure of mouse Myomaker bound to Fab18G7 in detergent | | 分子名称: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 18G7 Fab heavy chain, 18G7 Fab light chain, ... | | 著者 | Long, T, Li, X. | | 登録日 | 2023-05-31 | | 公開日 | 2023-09-27 | | 最終更新日 | 2023-11-22 | | 実験手法 | ELECTRON MICROSCOPY (2.72 Å) | | 主引用文献 | Cryo-EM structures of Myomaker reveal a molecular basis for myoblast fusion.
Nat.Struct.Mol.Biol., 30, 2023
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8T07
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8T04
 | | Structure of mouse Myomaker bound to Fab18G7 in nanodiscs | | 分子名称: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 18G7 Fab heavy chain, 18G7 Fab light chain, ... | | 著者 | Long, T, Li, X. | | 登録日 | 2023-05-31 | | 公開日 | 2023-09-27 | | 最終更新日 | 2023-11-22 | | 実験手法 | ELECTRON MICROSCOPY (2.98 Å) | | 主引用文献 | Cryo-EM structures of Myomaker reveal a molecular basis for myoblast fusion.
Nat.Struct.Mol.Biol., 30, 2023
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