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2AKM
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BU of 2akm by Molmil
Fluoride Inhibition of Enolase: Crystal Structure of the Inhibitory Complex
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Gamma enolase, MAGNESIUM ION, ...
著者Qin, J, Chai, G, Brewer, J.M, Lovelace, L.L.
登録日2005-08-03
公開日2006-03-21
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Fluoride inhibition of enolase: crystal structure and thermodynamics
Biochemistry, 45, 2006
8EC2
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BU of 8ec2 by Molmil
Mycobacterium phage Adephagia
分子名称: Major capsid protein
著者Podgorski, J.M, White, S.J.
登録日2022-09-01
公開日2023-02-01
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.4 Å)
主引用文献A structural dendrogram of the actinobacteriophage major capsid proteins provides important structural insights into the evolution of capsid stability.
Structure, 31, 2023
8ECJ
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Mycobacterium phage Cain
分子名称: Major capsid protein
著者Podgorski, J.M, White, S.J.
登録日2022-09-02
公開日2023-02-01
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献A structural dendrogram of the actinobacteriophage major capsid proteins provides important structural insights into the evolution of capsid stability.
Structure, 31, 2023
8ECN
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BU of 8ecn by Molmil
Mycobacterium phage Ogopogo
分子名称: Major capsid protein
著者Podgorski, J.M, White, S.J.
登録日2022-09-02
公開日2023-02-01
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献A structural dendrogram of the actinobacteriophage major capsid proteins provides important structural insights into the evolution of capsid stability.
Structure, 31, 2023
8EB4
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BU of 8eb4 by Molmil
Gordonia phage Ziko
分子名称: Major capsid protein
著者Podgorski, J.M, White, S.J.
登録日2022-08-30
公開日2023-02-01
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献A structural dendrogram of the actinobacteriophage major capsid proteins provides important structural insights into the evolution of capsid stability.
Structure, 31, 2023
8ECI
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BU of 8eci by Molmil
Arthrobacter phage Bridgette
分子名称: Decoration protein, Major capsid protein
著者Podgorski, J.M, White, S.J.
登録日2022-09-02
公開日2023-02-01
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献A structural dendrogram of the actinobacteriophage major capsid proteins provides important structural insights into the evolution of capsid stability.
Structure, 31, 2023
8E16
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Mycobacterium phage Che8
分子名称: Major capsid protein, gp6
著者Podgorski, J.M, White, S.J.
登録日2022-08-09
公開日2023-02-01
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献A structural dendrogram of the actinobacteriophage major capsid proteins provides important structural insights into the evolution of capsid stability.
Structure, 31, 2023
8EC8
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BU of 8ec8 by Molmil
Mycobacterium phage Bobi
分子名称: Major capsid protein
著者Podgorski, J.M, White, S.J.
登録日2022-09-01
公開日2023-02-01
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献A structural dendrogram of the actinobacteriophage major capsid proteins provides important structural insights into the evolution of capsid stability.
Structure, 31, 2023
8ECK
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BU of 8eck by Molmil
Gordonia phage Cozz
分子名称: Major capsid protein
著者Podgorski, J.M, White, S.J.
登録日2022-09-02
公開日2023-02-01
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献A structural dendrogram of the actinobacteriophage major capsid proteins provides important structural insights into the evolution of capsid stability.
Structure, 31, 2023
1YEZ
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BU of 1yez by Molmil
Solution structure of the conserved protein from the gene locus MM1357 of Methanosarcina mazei. Northeast Structural Genomics target MaR30.
分子名称: MM1357
著者Rossi, P, Aramini, J.M, Swapna, G.V.T, Huang, Y.P, Xiao, R, Ho, C.K, Ma, L.C, Acton, T.B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
登録日2004-12-29
公開日2005-02-22
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution structure of the conserved protein from the gene locus MM1357 of Methanosarcina mazei. Northeast Structural Genomics target MaR30.
To be Published
1YG6
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BU of 1yg6 by Molmil
ClpP
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ATP-dependent Clp protease proteolytic subunit
著者Bewley, M.C, Graziano, V, Griffin, K, Flanagan, J.M.
登録日2005-01-04
公開日2006-04-04
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The asymmetry in the mature amino-terminus of ClpP facilitates a local symmetry match in ClpAP and ClpXP complexes.
J.Struct.Biol., 153, 2006
1YNV
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BU of 1ynv by Molmil
Asp79 makes a large, unfavorable contribution to the stability of RNase Sa
分子名称: Guanyl-specific ribonuclease Sa, SULFATE ION
著者Trevino, S.R, Gokulan, K, Newsom, S, Thurlkill, R.L, Shaw, K.L, Mitkevich, V.A, Makarov, A.A, Sacchettini, J.C, Scholtz, J.M, Pace, C.N.
登録日2005-01-25
公開日2005-07-19
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Asp79 Makes a Large, Unfavorable Contribution to the Stability of RNase Sa.
J.Mol.Biol., 354, 2005
1YOK
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BU of 1yok by Molmil
crystal structure of human LRH-1 bound with TIF-2 peptide and phosphatidylglycerol
分子名称: (2S)-3-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-[(6E)-HEXADEC-6-ENOYLOXY]PROPYL (8E)-OCTADEC-8-ENOATE, Nuclear receptor coactivator 2, Orphan nuclear receptor NR5A2
著者Krylova, I.N, Sablin, E.P, Moore, J, Xu, R.X, Waitt, G.M, MacKay, J.A, Juzumiene, D, Bynum, J.M, Madauss, K, Montana, V, Lebedeva, L, Suzawa, M, Williams, J.D, Williams, S.P, Guy, R.K, Thornton, J.W, Fletterick, R.J, Willson, T.M, Ingraham, H.A.
登録日2005-01-27
公開日2005-07-19
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural analyses reveal phosphatidyl inositols as ligands for the NR5 orphan receptors SF-1 and LRH-1.
Cell(Cambridge,Mass.), 120, 2005
1YSX
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BU of 1ysx by Molmil
Solution structure of domain 3 from human serum albumin complexed to an anti-apoptotic ligand directed against Bcl-xL and Bcl-2
分子名称: 4-({2-[(2,4-DIMETHYLPHENYL)SULFANYL]ETHYL}AMINO)-N-[(4'-FLUORO-1,1'-BIPHENYL-4-YL)CARBONYL]-3-NITROBENZENESULFONAMIDE, Serum albumin
著者Oltersdorf, T, Elmore, S.W, Shoemaker, A.R, Armstrong, R.C, Augeri, D.J, Belli, B.A, Bruncko, M, Deckwerth, T.L, Dinges, J, Hajduk, P.J, Joseph, M.K, Kitada, S, Korsmeyer, S.J, Kunzer, A.R, Letai, A, Li, C, Mitten, M.J, Nettesheim, D.G, Ng, S, Nimmer, P.M, O'Connor, J.M, Oleksijew, A, Petros, A.M, Reed, J.C, Shen, W, Tahir, S.K, Thompson, C.B, Tomaselli, K.J, Wang, B, Wendt, M.D, Zhang, H, Fesik, S.W, Rosenberg, S.H.
登録日2005-02-09
公開日2005-06-07
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献An inhibitor of Bcl-2 family proteins induces regression of solid tumours
Nature, 435, 2005
8E17
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BU of 8e17 by Molmil
BRD4-D1 in complex with BET inhibitor
分子名称: (4P,6M)-6-[1-(2-fluoroethyl)-1H-1,2,3-triazol-4-yl]-4-[5-(methanesulfonyl)-2-methoxyphenyl]-2-methylisoquinolin-1(2H)-one, 1,2-ETHANEDIOL, Bromodomain-containing protein 4
著者Gorman, M.A, Fitzgerald, C.G.D, White, J.M, Parker, M.W.
登録日2022-08-09
公開日2023-03-29
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献Bromodomain and extraterminal protein-targeted probe enables tumour visualisation in vivo using positron emission tomography.
Chem.Commun.(Camb.), 59, 2023
8E3W
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BU of 8e3w by Molmil
BRD4-D1 in complex with BET inhibitor
分子名称: (4P)-4-[2-(cyclopropylmethoxy)-5-(methanesulfonyl)phenyl]-2-methylisoquinolin-1(2H)-one, 1,2-ETHANEDIOL, Bromodomain-containing protein 4
著者Gorman, M.A, Fitzgerald, C.G.D, White, J.M, Parker, M.W.
登録日2022-08-17
公開日2023-03-29
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献Bromodomain and extraterminal protein-targeted probe enables tumour visualisation in vivo using positron emission tomography.
Chem.Commun.(Camb.), 59, 2023
8DYR
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BU of 8dyr by Molmil
BRD4-D1 in complex with BET inhibitor
分子名称: (4P,6P)-4-[2-(cyclopropylmethoxy)-5-(methanesulfonyl)phenyl]-6-[1-(2-fluoroethyl)-1H-1,2,3-triazol-4-yl]-2-methylisoquinolin-1(2H)-one, 1,2-ETHANEDIOL, Bromodomain-containing protein 4
著者Gorman, M.A, Fitzgerald, C.G.D, White, J.M, Parker, M.W.
登録日2022-08-04
公開日2023-03-29
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献Bromodomain and extraterminal protein-targeted probe enables tumour visualisation in vivo using positron emission tomography.
Chem.Commun.(Camb.), 59, 2023
1YUC
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BU of 1yuc by Molmil
Human Nuclear Receptor Liver Receptor Homologue-1, LRH-1, Bound to Phospholipid and a Fragment of Human SHP
分子名称: GLYCEROL, L-ALPHA-PHOSPHATIDYL-BETA-OLEOYL-GAMMA-PALMITOYL-PHOSPHATIDYLETHANOLAMINE, Nuclear receptor 0B2, ...
著者Ortlund, E.A, Yoonkwang, L, Solomon, I.H, Hager, J.M, Safi, R, Choi, Y, Guan, Z, Tripathy, A, Raetz, C.R.H, McDonnell, D.P, Moore, D.D, Redinbo, M.R.
登録日2005-02-13
公開日2005-03-01
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Modulation of human nuclear receptor LRH-1 activity by phospholipids and SHP
Nat.Struct.Mol.Biol., 12, 2005
2B6F
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BU of 2b6f by Molmil
Solution structure of human sulfiredoxin (SRX)
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Sulfiredoxin
著者Gruschus, J.M, Lee, D.-Y, Ferretti, J.A, Rhee, S.G.
登録日2005-10-01
公開日2006-09-19
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Mutagenesis and Modeling of the Peroxiredoxin (Prx) Complex with the NMR Structure of ATP-Bound Human Sulfiredoxin Implicate Aspartate 187 of Prx I as the Catalytic Residue in ATP Hydrolysis
Biochemistry, 45, 2006
2B8Q
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BU of 2b8q by Molmil
X-ray structure of Acanthamoeba ployphaga mimivirus nucleoside diphosphate kinase complexed with TDP
分子名称: MAGNESIUM ION, PHOSPHATE ION, Probable nucleoside diphosphate kinase, ...
著者Jeudy, S, Claverie, J.M, Abergel, C.
登録日2005-10-10
公開日2005-11-15
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Dissecting the unique nucleotide specificity of mimivirus nucleoside diphosphate kinase.
J.Virol., 83, 2009
2B3V
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BU of 2b3v by Molmil
Spermine spermidine acetyltransferase in complex with acetylcoa, K26R mutant
分子名称: ACETYL COENZYME *A, Diamine acetyltransferase 1
著者Bewley, M.C, Graziano, V, Jiang, J.S, Matz, E, Studier, F.W, Pegg, A.P, Coleman, C.S, Flanagan, J.M, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2005-09-21
公開日2006-01-17
最終更新日2021-02-03
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structures of wild-type and mutant human spermidine/spermine N1-acetyltransferase, a potential therapeutic drug target.
Proc.Natl.Acad.Sci.USA, 103, 2006
2B4B
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BU of 2b4b by Molmil
SSAT+COA+BE-3-3-3, K26R mutant
分子名称: COENZYME A, Diamine acetyltransferase 1, N-ETHYL-N-[3-(PROPYLAMINO)PROPYL]PROPANE-1,3-DIAMINE
著者Bewley, M.C, Graziano, V, Jiang, J.S, Matz, E, Studier, F.W, Pegg, A.P, Coleman, C.S, Flanagan, J.M, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2005-09-23
公開日2006-01-17
最終更新日2023-05-24
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structures of wild-type and mutant human spermidine/spermine N1-acetyltransferase, a potential therapeutic drug target
Proc.Natl.Acad.Sci.Usa, 103, 2006
2BBS
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Human deltaF508 NBD1 with three solubilizing mutations
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION
著者Lewis, H.A, Kearins, M.C, Conners, K, Zhao, X, Lu, F, Sauder, J.M, Emtage, S.
登録日2005-10-17
公開日2005-11-01
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structure and dynamics of NBD1 from CFTR characterized using crystallography and hydrogen/deuterium exchange mass spectrometry.
J.Mol.Biol., 396, 2010
8DZZ
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Cryo-EM structure of chi dynein bound to Lis1
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Dynein heavy chain, ...
著者Reimer, J.M, Lahiri, I, Leschziner, A.E.
登録日2022-08-08
公開日2023-08-30
最終更新日2023-09-27
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Lis1 relieves cytoplasmic dynein-1 autoinhibition by acting as a molecular wedge.
Nat.Struct.Mol.Biol., 30, 2023
8E06
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Symmetry expansion of dimeric LRRK1
分子名称: GUANOSINE-5'-DIPHOSPHATE, Leucine-rich repeat serine/threonine-protein kinase 1
著者Reimer, J.M, Lin, Y.X, Leschziner, A.E.
登録日2022-08-08
公開日2023-08-30
最終更新日2023-11-29
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Structure of LRRK1 and mechanisms of autoinhibition and activation.
Nat.Struct.Mol.Biol., 30, 2023

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