1YNV

Asp79 makes a large, unfavorable contribution to the stability of RNase Sa

Summary for 1YNV

• Entry DOI: 10.2210/pdb1ynv/pdb
• Descriptor: Guanyl-specific ribonuclease Sa, SULFATE ION (3 entities in total)
• Functional Keywords: conformational stability, electrostatic strain, pka, hydrogen bonds and ion pair., hydrolase
• Biological source: Streptomyces aureofaciens
• Cellular location: Secreted: P05798
• Total number of polymer chains: 1
• Total formula weight: 10679.61

Authors

Trevino, S.R.,Gokulan, K.,Newsom, S.,Thurlkill, R.L.,Shaw, K.L.,Mitkevich, V.A.,Makarov, A.A.,Sacchettini, J.C.,Scholtz, J.M.,Pace, C.N. (deposition date: 2005-01-25, release date: 2005-07-19, Last modification date: 2023-08-23)

• Primary citation: Trevino, S.R.,Gokulan, K.,Newsom, S.,Thurlkill, R.L.,Shaw, K.L.,Mitkevich, V.A.,Makarov, A.A.,Sacchettini, J.C.,Scholtz, J.M.,Pace, C.N.; Asp79 Makes a Large, Unfavorable Contribution to the Stability of RNase Sa.; J.Mol.Biol., 354:967-978, 2005; PubMed: 16288913; DOI: 10.1016/j.jmb.2005.09.091

Experimental method

X-RAY DIFFRACTION (1.2 Å)