8J4T
 
 | | GajA-GajB complex | | 分子名称: | Endonuclease GajA, Gabija protein GajB | | 著者 | Wei, T, Ma, J, Huo, Y. | | 登録日 | 2023-04-20 | | 公開日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structural and biochemical insights into the mechanism of the Gabija bacterial immunity system.
Nat Commun, 15, 2024
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8HXB
 | | Cryo-EM structure of MPXV M2 hexamer in complex with human B7.2 | | 分子名称: | NFkB inhibitor, T-lymphocyte activation antigen CD86 | | 著者 | Wang, Y, Yang, S, Zhao, H, Deng, Z. | | 登録日 | 2023-01-04 | | 公開日 | 2023-08-30 | | 最終更新日 | 2023-12-13 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Structural and functional insights into the modulation of T cell costimulation by monkeypox virus protein M2.
Nat Commun, 14, 2023
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8HXC
 | | Cryo-EM structure of MPXV M2 heptamer in complex with human B7.2 | | 分子名称: | NFkB inhibitor, T-lymphocyte activation antigen CD86 | | 著者 | Wang, Y, Yang, S, Zhao, H, Deng, Z. | | 登録日 | 2023-01-04 | | 公開日 | 2023-08-30 | | 最終更新日 | 2023-12-13 | | 実験手法 | ELECTRON MICROSCOPY (3.12 Å) | | 主引用文献 | Structural and functional insights into the modulation of T cell costimulation by monkeypox virus protein M2.
Nat Commun, 14, 2023
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8HXA
 | | Cryo-EM structure of MPXV M2 in complex with human B7.1 | | 分子名称: | NFkB inhibitor, T-lymphocyte activation antigen CD80 | | 著者 | Wang, Y, Yang, S, Zhao, H, Deng, Z. | | 登録日 | 2023-01-04 | | 公開日 | 2023-08-30 | | 最終更新日 | 2023-12-13 | | 実験手法 | ELECTRON MICROSCOPY (3.04 Å) | | 主引用文献 | Structural and functional insights into the modulation of T cell costimulation by monkeypox virus protein M2.
Nat Commun, 14, 2023
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6JW1
 | | Universal RVD R* accommodates 5mC via water-mediated interactions | | 分子名称: | DNA (5'-D(*AP*GP*AP*GP*AP*CP*GP*CP*GP*AP*AP*GP*GP*GP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*CP*CP*CP*TP*TP*(5CM)P*GP*CP*GP*TP*CP*TP*CP*T)-3'), TAL effector | | 著者 | Liu, L, Yi, C. | | 登録日 | 2019-04-18 | | 公開日 | 2020-04-22 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | | 主引用文献 | Structural Insights into the Specific Recognition of 5-methylcytosine and 5-hydroxymethylcytosine by TAL Effectors.
J.Mol.Biol., 432, 2020
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7W6L
 | | The crystal structure of MLL3-RBBP5-ASH2L in complex with H3K4me0 peptide | | 分子名称: | Histone H3.3C, Histone-lysine N-methyltransferase 2C, Retinoblastoma-binding protein 5, ... | | 著者 | Zhao, L, Li, Y, Chen, Y. | | 登録日 | 2021-12-01 | | 公開日 | 2022-09-07 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | | 主引用文献 | Structural basis for product specificities of MLL family methyltransferases.
Mol.Cell, 82, 2022
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6JW2
 | | Universal RVD R* accommodates 5hmC via water-mediated interactions | | 分子名称: | DNA (5'-D(*AP*GP*AP*GP*AP*CP*GP*CP*GP*AP*AP*GP*GP*GP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*CP*CP*CP*TP*TP*(5HC)P*GP*CP*GP*TP*CP*TP*CP*T)-3'), TAL effector | | 著者 | Liu, L, Yi, C. | | 登録日 | 2019-04-18 | | 公開日 | 2020-04-22 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.03 Å) | | 主引用文献 | Structural Insights into the Specific Recognition of 5-methylcytosine and 5-hydroxymethylcytosine by TAL Effectors.
J.Mol.Biol., 432, 2020
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6JVZ
 | | RVD HA specifically contacts 5mC through van der Waals interactions | | 分子名称: | DNA (5'-D(*AP*GP*AP*GP*AP*CP*GP*CP*GP*AP*AP*GP*GP*GP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*CP*CP*CP*TP*TP*(5CM)P*GP*CP*GP*TP*CP*TP*CP*T)-3'), TAL effector | | 著者 | Liu, L, Yi, C. | | 登録日 | 2019-04-18 | | 公開日 | 2020-04-22 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | | 主引用文献 | Structural Insights into the Specific Recognition of 5-methylcytosine and 5-hydroxymethylcytosine by TAL Effectors.
J.Mol.Biol., 432, 2020
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6IYV
 | | Crystal sturucture of L,D-transpeptidase LdtMt2 from Mycobacterium tuberculosis in complex with ertapenem adduct | | 分子名称: | (2S,3R,4S)-4-({(3S,5S)-5-[(3-carboxyphenyl)carbamoyl]pyrrolidin-3-yl}sulfanyl)-2-[(1S,2R)-1-formyl-2-hydroxypropyl]-3-methyl-3,4-dihydro-2H-pyrrole-5-carboxylic acid, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Zhao, F, Li, D.F, Wang, D.C. | | 登録日 | 2018-12-17 | | 公開日 | 2019-02-27 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | The 1-beta-methyl group confers a lower affinity of l,d-transpeptidase LdtMt2for ertapenem than for imipenem.
Biochem. Biophys. Res. Commun., 510, 2019
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6K62
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6KQU
 | | Crystal structure of phospholipase A2 | | 分子名称: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Hou, S, Xu, T, Liu, J. | | 登録日 | 2019-08-18 | | 公開日 | 2020-08-19 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Residue Asn21 acts as a switch for calcium binding to modulate the enzymatic activity of human phospholipase A2 group IIE.
Biochimie, 176, 2020
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8H3Z
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7VWZ
 | | Cryo-EM structure of Rob-dependent transcription activation complex in a unique conformation | | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | 著者 | Lin, W, Feng, Y, Shi, J. | | 登録日 | 2021-11-12 | | 公開日 | 2022-06-08 | | 最終更新日 | 2024-06-26 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Structural basis of transcription activation by Rob, a pleiotropic AraC/XylS family regulator.
Nucleic Acids Res., 50, 2022
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7VWY
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7VEH
 | | Type I-F Anti-CRISPR protein AcrIF13 | | 分子名称: | AcrIF13 | | 著者 | Gao, T, Feng, Y. | | 登録日 | 2021-09-08 | | 公開日 | 2022-07-06 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Mechanistic insights into the inhibition of the CRISPR-Cas surveillance complex by anti-CRISPR protein AcrIF13.
J.Biol.Chem., 298, 2022
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7VLN
 | | NSD2-PWWP1 domain bound with an imidazol-5-yl benzonitrile compound | | 分子名称: | 4-[5-[4-(aminomethyl)-2,6-dimethoxy-phenyl]-3-methyl-imidazol-4-yl]benzenecarbonitrile, Histone-lysine N-methyltransferase NSD2 | | 著者 | Cao, D.Y, Li, Y.L, Li, J, Xiong, B. | | 登録日 | 2021-10-05 | | 公開日 | 2022-07-06 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.09 Å) | | 主引用文献 | Structure-Based Discovery of a Series of NSD2-PWWP1 Inhibitors.
J.Med.Chem., 65, 2022
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7E8O
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7E8K
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7E8J
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7DZE
 | | Fabp ground state captured by XFELs | | 分子名称: | Fatty acid-binding protein, liver, PALMITIC ACID | | 著者 | Li, H, Yu, L.-J, Liu, X, Shen, J.-R, Wang, J. | | 登録日 | 2021-01-25 | | 公開日 | 2022-07-27 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Excited-state intermediates in a designer protein encoding a phototrigger caught by an X-ray free-electron laser.
Nat.Chem., 14, 2022
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7DZH
 | | intermediate of FABP with a delay time of 100 ns | | 分子名称: | Fatty acid-binding protein, liver, PALMITIC ACID | | 著者 | Li, H, Yu, L.-J, Liu, X, Shen, J.-R, Wang, J. | | 登録日 | 2021-01-25 | | 公開日 | 2022-07-27 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Excited-state intermediates in a designer protein encoding a phototrigger caught by an X-ray free-electron laser.
Nat.Chem., 14, 2022
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7DZF
 | | Intermediate of FABP with a delay time of 10 ns | | 分子名称: | Fatty acid-binding protein, liver, PALMITIC ACID | | 著者 | Li, H, Yu, L.-J, Liu, X, Shen, J.-R, Wang, J. | | 登録日 | 2021-01-25 | | 公開日 | 2022-07-27 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Excited-state intermediates in a designer protein encoding a phototrigger caught by an X-ray free-electron laser.
Nat.Chem., 14, 2022
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7DZG
 | | Intermediate of FABP with a delay time of 30 ns | | 分子名称: | Fatty acid-binding protein, liver, PALMITIC ACID | | 著者 | Li, H, Yu, L.-J, Liu, X, Shen, J.-R, Wang, J. | | 登録日 | 2021-01-25 | | 公開日 | 2022-07-27 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Excited-state intermediates in a designer protein encoding a phototrigger caught by an X-ray free-electron laser.
Nat.Chem., 14, 2022
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7DZI
 | | intermediate of FABP with a delay time of 300 ns | | 分子名称: | Fatty acid-binding protein, liver, PALMITIC ACID | | 著者 | Li, H, Yu, L.-J, Liu, X, Shen, J.-R, Wang, J. | | 登録日 | 2021-01-25 | | 公開日 | 2022-07-27 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Excited-state intermediates in a designer protein encoding a phototrigger caught by an X-ray free-electron laser.
Nat.Chem., 14, 2022
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7DZJ
 | | Fabp protein before hv | | 分子名称: | Fatty acid-binding protein, liver, PALMITIC ACID | | 著者 | Li, H, Yu, L.-J, Liu, X, Shen, J.-R, Wang, J. | | 登録日 | 2021-01-25 | | 公開日 | 2022-07-27 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | | 主引用文献 | Excited-state intermediates in a designer protein encoding a phototrigger caught by an X-ray free-electron laser.
Nat.Chem., 14, 2022
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