6KQU

Crystal structure of phospholipase A2

Summary for 6KQU

• Entry DOI: 10.2210/pdb6kqu/pdb
• Related: 5Y5E
• Descriptor: Group IIE secretory phospholipase A2, GLYCEROL, CHLORIDE ION, ... (7 entities in total)
• Functional Keywords: phospholipase a2, mutation, calcium, hydrolase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 14671.39

Authors

Hou, S.,Xu, T.,Liu, J. (deposition date: 2019-08-18, release date: 2020-08-19, Last modification date: 2023-11-22)

• Primary citation: Hou, S.,Zhang, Y.,Xu, J.,Bai, J.,Liu, J.,Xie, J.,Xu, T.; Residue Asn21 acts as a switch for calcium binding to modulate the enzymatic activity of human phospholipase A2 group IIE.; Biochimie, 176:117-121, 2020; PubMed: 32659444; DOI: 10.1016/j.biochi.2020.07.003

Experimental method

X-RAY DIFFRACTION (2 Å)