6KQU
Crystal structure of phospholipase A2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Group IIE secretory phospholipase A2 | polymer | 123 | 13929.1 | 1 | UniProt (Q9NZK7) Pfam (PF00068) | Homo sapiens (Human) | sPLA2-IIE,Phosphatidylcholine 2-acylhydrolase 2E |
| 2 | B, C (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 3 | D, E, F, G, H... (A) | CHLORIDE ION | non-polymer | 35.5 | 6 | Chemie (CL) | |||
| 4 | J (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 5 | K (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 6 | L (A) | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 282.3 | 1 | Chemie (B3P) | |||
| 7 | M (A) | water | water | 18.0 | 150 | Chemie (HOH) |
Sequence modifications
A: 1 - 123 (UniProt: Q9NZK7)
| PDB | External Database | Details |
|---|---|---|
| Gly 21 | Asn 40 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 13929.1 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 742.3 | |
| All* | Total formula weight | 14671.4 |
