5MMO
 
 | E. coli DNA Gyrase B 24 kDa ATPase domain in complex with [3-(3-ethyl-ureido)-5-(pyridin-4-yl)-isoquinolin-8-yl-methyl]-carbamic acid prop-2-ynyl ester | 分子名称: | DNA gyrase subunit B, PHOSPHATE ION, prop-2-ynyl ~{N}-[[3-(ethylcarbamoylamino)-5-pyridin-4-yl-isoquinolin-8-yl]methyl]carbamate | 著者 | Panchaud, P, Bruyere, T, Blumstein, A.-C, Bur, D, Chambovey, A, Ertel, E.A, Gude, M, Hubschwerlen, C, Jacob, L, Kimmerlin, T, Pfeifer, T, Prade, L, Seiler, P, Ritz, D, Rueedi, G. | 登録日 | 2016-12-12 | 公開日 | 2017-04-26 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | 主引用文献 | Discovery and Optimization of Isoquinoline Ethyl Ureas as Antibacterial Agents. J. Med. Chem., 60, 2017
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9FLM
 
 | Crystal structure of the C-terminal domain of VldE from Streptococcus pneumoniae in a catalytically competent conformation | 分子名称: | LysM domain-containing protein, ZINC ION | 著者 | Miguel-Ruano, V, Acebron, I, P.de Jose, U, Straume, D, Havarstein, L.S, Hermoso, J.A. | 登録日 | 2024-06-05 | 公開日 | 2025-01-22 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Characterization of VldE (Spr1875), a Pneumococcal Two-State l,d-Endopeptidase with a Four-Zinc Cluster in the Active Site. Acs Catalysis, 14, 2024
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7CR4
 
 | human KCNQ2-CaM in complex with ztz240 | 分子名称: | Calmodulin-3, N-(6-chloranylpyridin-3-yl)-4-fluoranyl-benzamide, Potassium voltage-gated channel subfamily KQT member 2 | 著者 | Li, X, Lv, D, Wang, J, Ye, S, Guo, J. | 登録日 | 2020-08-12 | 公開日 | 2020-09-16 | 最終更新日 | 2025-07-02 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Molecular basis for ligand activation of the human KCNQ2 channel. Cell Res., 31, 2021
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7CRB
 
 | Cryo-EM structure of plant NLR RPP1 LRR-ID domain in complex with ATR1 | 分子名称: | Avirulence protein ATR1, NAD+ hydrolase (NADase) | 著者 | Ma, S.C, Lapin, D, Liu, L, Sun, Y, Song, W, Zhang, X.X, Logemann, E, Yu, D.L, Wang, J, Jirschitzka, J, Han, Z.F, SchulzeLefert, P, Parker, J.E, Chai, J.J. | 登録日 | 2020-08-13 | 公開日 | 2020-12-16 | 最終更新日 | 2025-07-02 | 実験手法 | ELECTRON MICROSCOPY (3.16 Å) | 主引用文献 | Direct pathogen-induced assembly of an NLR immune receptor complex to form a holoenzyme. Science, 370, 2020
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9FLN
 
 | Crystal structure of the C-terminal domain of VldE H373A from Streptococcus pneumoniae | 分子名称: | LysM domain-containing protein, ZINC ION | 著者 | Miguel-Ruano, V, Acebron, I, P.de Jose, U, Straume, D, Havarstein, L.S, Hermoso, J.A. | 登録日 | 2024-06-05 | 公開日 | 2025-01-22 | 実験手法 | X-RAY DIFFRACTION (1.14 Å) | 主引用文献 | Characterization of VldE (Spr1875), a Pneumococcal Two-State l,d-Endopeptidase with a Four-Zinc Cluster in the Active Site. Acs Catalysis, 14, 2024
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5LOQ
 
 | Structure of coproheme bound HemQ from Listeria monocytogenes | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,3,5,8-TETRAMETHYL-PORPHINE-2,4,6,7-TETRAPROPIONIC ACID FERROUS COMPLEX, Putative heme-dependent peroxidase lmo2113, ... | 著者 | Puehringer, D, Mlynek, G, Hofbauer, S, Djinovic-Carugo, K, Obinger, C. | 登録日 | 2016-08-09 | 公開日 | 2016-10-26 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | 主引用文献 | Hydrogen peroxide-mediated conversion of coproheme to heme b by HemQ-lessons from the first crystal structure and kinetic studies. FEBS J., 283, 2016
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9J1M
 
 | KU13-bond Mycobacterium tuberculosis 70S ribosome | 分子名称: | (2~{R},3~{R},4~{R},5~{R},8~{R},10~{R},11~{R},12~{S},13~{S},14~{R})-11-[(2~{S},3~{R},4~{S},6~{R})-4-(dimethylamino)-6-methyl-3-oxidanyl-oxan-2-yl]oxy-2-ethyl-4-[(2~{R},3~{R},4~{R},5~{S},6~{R})-6-(hydroxymethyl)-3,4-bis(oxidanyl)-5-[[4-(4-pyridin-4-yl-1,2,3-triazol-1-yl)phenyl]methoxy]oxan-2-yl]oxy-13-[(2~{R},4~{R},5~{S},6~{S})-4-methoxy-4,6-dimethyl-5-oxidanyl-oxan-2-yl]oxy-3,5,6,8,10,12,14-heptamethyl-3,10-bis(oxidanyl)-1-oxa-6-azacyclopentadecan-15-one, 16S rRNA, 23S rRNA, ... | 著者 | Nishihara, D, Fujino, M, Tanaka, Y, Yokoyama, T. | 登録日 | 2024-08-05 | 公開日 | 2025-03-19 | 実験手法 | ELECTRON MICROSCOPY (2.33 Å) | 主引用文献 | Creation of a macrolide antibiotic against non-tuberculous Mycobacterium using late-stage boron-mediated aglycon delivery. Sci Adv, 11, 2025
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6TUA
 
 | The RYK Pseudokinase Domain | 分子名称: | SULFATE ION, Tyrosine-protein kinase RYK | 著者 | Mathea, S, Chatterjee, D, Preuss, F, Shin, D, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S. | 登録日 | 2020-01-04 | 公開日 | 2020-01-15 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | 主引用文献 | Structural Insights into Pseudokinase Domains of Receptor Tyrosine Kinases. Mol.Cell, 79, 2020
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7UEL
 
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7UEM
 
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7U0L
 
 | Crystal structure of the CCoV-HuPn-2018 RBD (domain B) in complex with canine APN | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Aminopeptidase N, ... | 著者 | Tortorici, M.A, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 登録日 | 2022-02-18 | 公開日 | 2022-08-24 | 最終更新日 | 2024-11-06 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Structure, receptor recognition, and antigenicity of the human coronavirus CCoV-HuPn-2018 spike glycoprotein. Cell, 185, 2022
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7UEN
 
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7US9
 
 | CCoV-HuPn-2018 S in the proximal conformation (local refinement of domain 0) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | 著者 | Tortorici, M.A, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 登録日 | 2022-04-23 | 公開日 | 2022-08-24 | 最終更新日 | 2024-10-30 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structure, receptor recognition, and antigenicity of the human coronavirus CCoV-HuPn-2018 spike glycoprotein. Cell, 185, 2022
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7US6
 
 | Structure of the human coronavirus CCoV-HuPn-2018 spike glycoprotein with domain 0 in the proximal conformation | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | 著者 | Tortorici, M.A, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 登録日 | 2022-04-23 | 公開日 | 2022-08-24 | 最終更新日 | 2024-11-13 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structure, receptor recognition, and antigenicity of the human coronavirus CCoV-HuPn-2018 spike glycoprotein. Cell, 185, 2022
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7USB
 
 | CCoV-HuPn-2018 S in the swung out conformation (local refinement of domain 0) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | 著者 | Tortorici, M.A, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 登録日 | 2022-04-23 | 公開日 | 2022-08-24 | 最終更新日 | 2024-11-13 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structure, receptor recognition, and antigenicity of the human coronavirus CCoV-HuPn-2018 spike glycoprotein. Cell, 185, 2022
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9IN8
 
 | True-atomic resolution crystal structure of the open state of the viral channelrhodopsin OLPVR1 | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-2,3-dihydroxypropyl (9Z)-hexadec-9-enoate, EICOSANE, ... | 著者 | Bukhdruker, S, Zabelskii, D, Astashkin, R, Bourenkov, G, Gordeliy, V. | 登録日 | 2024-07-05 | 公開日 | 2025-03-12 | 最終更新日 | 2025-04-23 | 実験手法 | X-RAY DIFFRACTION (1.34 Å) | 主引用文献 | Ion-conducting and gating molecular mechanisms of channelrhodopsin revealed by true-atomic-resolution structures of open and closed states. Nat.Struct.Mol.Biol., 2025
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1UPU
 
 | STRUCTURE OF THE URACIL PHOSPHORIBOSYLTRANSFERASE, MUTANT C128V, BOUND TO PRODUCT URIDINE-1-MONOPHOSPHATE (UMP) | 分子名称: | PHOSPHATE ION, URACIL PHOSPHORIBOSYLTRANSFERASE, URIDINE-5'-MONOPHOSPHATE | 著者 | Schumacher, M.A, Carter, D, Scott, D, Roos, D, Ullman, B, Brennan, R.G. | 登録日 | 1998-04-16 | 公開日 | 1999-05-11 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structures of Toxoplasma gondii uracil phosphoribosyltransferase reveal the atomic basis of pyrimidine discrimination and prodrug binding. EMBO J., 17, 1998
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9IN9
 
 | Structure of the viral channelrhodopsin OLPVR1 at low pH obtained by soaking | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-2,3-dihydroxypropyl (9Z)-hexadec-9-enoate, EICOSANE, ... | 著者 | Bukhdruker, S, Zabelskii, D, Astashkin, R, Gordeliy, V. | 登録日 | 2024-07-05 | 公開日 | 2025-03-12 | 最終更新日 | 2025-04-23 | 実験手法 | X-RAY DIFFRACTION (1.41 Å) | 主引用文献 | Ion-conducting and gating molecular mechanisms of channelrhodopsin revealed by true-atomic-resolution structures of open and closed states. Nat.Struct.Mol.Biol., 2025
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9IN7
 
 | True-atomic resolution crystal structure of the closed state of the viral channelrhodopsin OLPVR1 | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-2,3-dihydroxypropyl (9Z)-hexadec-9-enoate, EICOSANE, ... | 著者 | Bukhdruker, S, Zabelskii, D, Astashkin, R, Gordeliy, V. | 登録日 | 2024-07-05 | 公開日 | 2025-03-12 | 最終更新日 | 2025-04-23 | 実験手法 | X-RAY DIFFRACTION (1.13 Å) | 主引用文献 | Ion-conducting and gating molecular mechanisms of channelrhodopsin revealed by true-atomic-resolution structures of open and closed states. Nat.Struct.Mol.Biol., 2025
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7USF
 
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7LXW
 
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7USA
 
 | Structure of the human coronavirus CCoV-HuPn-2018 spike glycoprotein with domain 0 in the swung out conformation | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | 著者 | Tortorici, M.A, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 登録日 | 2022-04-23 | 公開日 | 2022-08-24 | 最終更新日 | 2024-11-20 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Structure, receptor recognition, and antigenicity of the human coronavirus CCoV-HuPn-2018 spike glycoprotein. Cell, 185, 2022
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7LY0
 
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9C6O
 
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6FJS
 
 | Proteinase~K SIRAS phased structure of room-temperature, serially collected synchrotron data | 分子名称: | CALCIUM ION, Proteinase K | 著者 | Botha, S, Baitan, D, Jungnickel, K.E.J, Oberthuer, D, Schmidt, C, Stern, S, Wiedorn, M.O, Perbandt, M, Chapman, H.N, Betzel, C. | 登録日 | 2018-01-23 | 公開日 | 2018-10-10 | 最終更新日 | 2024-11-06 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | De novoprotein structure determination by heavy-atom soaking in lipidic cubic phase and SIRAS phasing using serial synchrotron crystallography. IUCrJ, 5, 2018
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