3AJF
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5YTX
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5YTT
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5YTS
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5YTV
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8JFL
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8JFK
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8H3U
| Inhibitor-bound EP, polyA model | 分子名称: | Enteropeptidase catalytic light chain, Enteropeptidase non-catalytic heavy chain | 著者 | Ding, Z.Y, Huang, H.J. | 登録日 | 2022-10-09 | 公開日 | 2022-11-23 | 最終更新日 | 2024-10-09 | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | 主引用文献 | Cryo-EM structures reveal the activation and substrate recognition mechanism of human enteropeptidase. Nat Commun, 13, 2022
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8H3S
| Substrate-bound EP, polyA model | 分子名称: | Enteropeptidase catalytic light chain, Enteropeptidase non-catalytic heavy chain, Serine protease 1 | 著者 | Ding, Z.Y, Huang, H.J. | 登録日 | 2022-10-09 | 公開日 | 2022-11-23 | 実験手法 | ELECTRON MICROSCOPY (4.9 Å) | 主引用文献 | Cryo-EM structures reveal the activation and substrate recognition mechanism of human enteropeptidase. Nat Commun, 13, 2022
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7CI0
| Microbial Hormone-sensitive lipase E53 mutant S162A | 分子名称: | 1,2-ETHANEDIOL, 1,4-DIETHYLENE DIOXIDE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... | 著者 | Yang, X, Li, Z, Xu, X, Li, J. | 登録日 | 2020-07-06 | 公開日 | 2021-07-14 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Mechanism and Structural Insights Into a Novel Esterase, E53, Isolated From Erythrobacter longus . Front Microbiol, 12, 2021
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7CIH
| Microbial Hormone-sensitive lipase E53 mutant S285G | 分子名称: | (4-nitrophenyl) hexanoate, 1,2-ETHANEDIOL, 1,4-DIETHYLENE DIOXIDE, ... | 著者 | Yang, X, Li, Z, Xu, X, Li, J. | 登録日 | 2020-07-07 | 公開日 | 2021-07-14 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.789 Å) | 主引用文献 | Mechanism and Structural Insights Into a Novel Esterase, E53, Isolated From Erythrobacter longus . Front Microbiol, 12, 2021
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7WV9
| Allosteric modulator ZCZ011 binding to CP55940-bound cannabinoid receptor 1 in complex with Gi protein | 分子名称: | 2-[(1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohexyl]-5-(2-methyloctan-2-yl)phenol, 6-methyl-3-[(1S)-2-nitro-1-thiophen-2-yl-ethyl]-2-phenyl-1H-indole, Cannabinoid receptor 1, ... | 著者 | Xu, Z, Shao, Z. | 登録日 | 2022-02-10 | 公開日 | 2022-06-15 | 最終更新日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (3.36 Å) | 主引用文献 | Molecular mechanism of allosteric modulation for the cannabinoid receptor CB1. Nat.Chem.Biol., 18, 2022
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6A0A
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6A0C
| Structure of a triple-helix region of human collagen type III | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, collagen type III peptide | 著者 | Yang, X, Zhu, Y, Ye, S, Zhang, R. | 登録日 | 2018-06-05 | 公開日 | 2018-12-26 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.501 Å) | 主引用文献 | Characterization by high-resolution crystal structure analysis of a triple-helix region of human collagen type III with potent cell adhesion activity. Biochem. Biophys. Res. Commun., 508, 2019
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7W8N
| Microbial Hormone-sensitive lipase E53 wild type | 分子名称: | (4-nitrophenyl) hexanoate, 1,2-ETHANEDIOL, 1,4-DIETHYLENE DIOXIDE, ... | 著者 | Yang, X, Li, Z, Xu, X, Li, J. | 登録日 | 2021-12-08 | 公開日 | 2022-02-23 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Mechanism and Structural Insights Into a Novel Esterase, E53, Isolated From Erythrobacter longus . Front Microbiol, 12, 2021
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7V53
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7WQZ
| Structure of Active-mutEP | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Enteropeptidase catalytic light chain, Enteropeptidase non-catalytic heavy chain | 著者 | Yang, X.L, Ding, Z.Y, Huang, H.J. | 登録日 | 2022-01-26 | 公開日 | 2022-10-26 | 最終更新日 | 2022-11-23 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Cryo-EM structures reveal the activation and substrate recognition mechanism of human enteropeptidase. Nat Commun, 13, 2022
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7WR7
| Structure of Inhibited-EP | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-carbamimidamidobenzoic acid, Enteropeptidase catalytic light chain, ... | 著者 | Yang, X.L, Ding, Z.Y, Huang, H.J. | 登録日 | 2022-01-26 | 公開日 | 2022-10-26 | 最終更新日 | 2022-11-23 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Cryo-EM structures reveal the activation and substrate recognition mechanism of human enteropeptidase. Nat Commun, 13, 2022
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7WDK
| The structure of PldA-PA3488 complex | 分子名称: | Phospholipase D, Tli4_C domain-containing protein | 著者 | Zhao, L, Yang, X.Y, Li, Z.Q. | 登録日 | 2021-12-21 | 公開日 | 2022-10-26 | 最終更新日 | 2022-11-09 | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | 主引用文献 | Structural insights into PA3488-mediated inactivation of Pseudomonas aeruginosa PldA Nat Commun, 13, 2022
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7WQW
| Structure of Active-EP | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Enteropeptidase catalytic light chain, Enteropeptidase non-catalytic heavy chain | 著者 | Yang, X.L, Ding, Z.Y, Huang, H.J. | 登録日 | 2022-01-26 | 公開日 | 2022-10-26 | 最終更新日 | 2024-10-16 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Cryo-EM structures reveal the activation and substrate recognition mechanism of human enteropeptidase. Nat Commun, 13, 2022
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7WQX
| Structure of Inactive-EP | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Enteropeptidase | 著者 | Yang, X.L, Ding, Z.Y, Huang, H.J. | 登録日 | 2022-01-26 | 公開日 | 2022-10-26 | 最終更新日 | 2022-11-23 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Cryo-EM structures reveal the activation and substrate recognition mechanism of human enteropeptidase. Nat Commun, 13, 2022
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7V55
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6CHZ
| Estrogen Receptor Alpha Y537S bound to antagonist H3B-9224. | 分子名称: | 1,2-ETHANEDIOL, 4-[(2-{4-[(1E)-1-(1H-indazol-5-yl)-2-phenylbut-1-en-1-yl]phenoxy}ethyl)amino]-N,N-dimethylbutanamide, Estrogen receptor | 著者 | Larsen, N.A. | 登録日 | 2018-02-23 | 公開日 | 2018-03-21 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | 主引用文献 | Discovery of Selective Estrogen Receptor Covalent Antagonists for the Treatment of ER alphaWTand ER alphaMUTBreast Cancer. Cancer Discov, 8, 2018
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6CHW
| Estrogen Receptor Alpha Y537S covalently bound to antagonist H3B-5942. | 分子名称: | 1,2-ETHANEDIOL, 4-[(2-{4-[(1E)-1-(1H-indazol-5-yl)-2-phenylbut-1-en-1-yl]phenoxy}ethyl)amino]-N,N-dimethylbutanamide, DIMETHYL SULFOXIDE, ... | 著者 | Larsen, N.A. | 登録日 | 2018-02-23 | 公開日 | 2018-03-21 | 最終更新日 | 2020-02-26 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | Discovery of Selective Estrogen Receptor Covalent Antagonists for the Treatment of ER alphaWTand ER alphaMUTBreast Cancer. Cancer Discov, 8, 2018
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8RYZ
| Structures of selenoneine synthase SenA from Variovorax paradoxus | 分子名称: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, GLYCEROL, IMIDAZOLE, ... | 著者 | Ma, Y.Y, Gao, Y, Xu, S.H. | 登録日 | 2024-02-11 | 公開日 | 2024-09-11 | 最終更新日 | 2024-09-18 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | Structures of SenB and SenA enzymes from Variovorax paradoxus provide insights into carbon-selenium bond formation in selenoneine biosynthesis. Heliyon, 10, 2024
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