2LCT
 
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4AP5
 | | Crystal structure of human POFUT2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 2, ... | | 著者 | Chen, C, Keusch, J.J, Klein, D, Hess, D, Hofsteenge, J, Gut, H. | | 登録日 | 2012-03-30 | | 公開日 | 2012-08-08 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (3.003 Å) | | 主引用文献 | Structure of Human Pofut2: Insights Into Thrombospondin Type 1 Repeat Fold and O-Fucosylation.
Embo J., 31, 2012
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4AP6
 | | Crystal structure of human POFUT2 E54A mutant in complex with GDP- fucose | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 2, ... | | 著者 | Chen, C, Keusch, J.J, Klein, D, Hess, D, Hofsteenge, J, Gut, H. | | 登録日 | 2012-03-30 | | 公開日 | 2012-08-08 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (3.401 Å) | | 主引用文献 | Structure of Human Pofut2: Insights Into Thrombospondin Type 1 Repeat Fold and O-Fucosylation.
Embo J., 31, 2012
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4EFH
 | | Acanthamoeba Actin complex with Spir domain D | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin-1, CALCIUM ION, ... | | 著者 | Chen, C, Phillips, M, Sawaya, M.R, Quinlan, M.E. | | 登録日 | 2012-03-29 | | 公開日 | 2012-04-11 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | | 主引用文献 | Multiple Forms of Spire-Actin Complexes and their Functional Consequences.
J.Biol.Chem., 287, 2012
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3UE5
 | | ECP-cleaved Actin in complex with Spir domain D | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ... | | 著者 | Chen, C, Phillips, M, Sawaya, M.R, Ralston, C.Y, Quinlan, M.E. | | 登録日 | 2011-10-28 | | 公開日 | 2012-02-15 | | 最終更新日 | 2012-04-11 | | 実験手法 | X-RAY DIFFRACTION (2.76 Å) | | 主引用文献 | Multiple Forms of Spire-Actin Complexes and their Functional Consequences.
J.Biol.Chem., 287, 2012
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4JDK
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4JCN
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4JDH
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4JDI
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4JDJ
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3FDR
 | | Crystal structure of TDRD2 | | 分子名称: | Tudor and KH domain-containing protein | | 著者 | Amaya, M.F, Adams, M.A, Guo, Y, Li, Y, Kozieradzki, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Bountra, C, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC) | | 登録日 | 2008-11-26 | | 公開日 | 2009-01-06 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Mouse Piwi interactome identifies binding mechanism of Tdrkh Tudor domain to arginine methylated Miwi
Proc.Natl.Acad.Sci.USA, 106, 2009
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7WNJ
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7W5J
 | | The structure of trichobrasilenol synthase TaTC6 in complex with FPP-2 | | 分子名称: | FARNESYL, FARNESYL DIPHOSPHATE, GLYCEROL, ... | | 著者 | Chen, C, Wang, T, Yang, Y, Zhang, L, Ko, T, Huang, J, Guo, R. | | 登録日 | 2021-11-30 | | 公開日 | 2022-06-01 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Structural insights into the cyclization of unusual brasilane-type sesquiterpenes.
Int.J.Biol.Macromol., 209, 2022
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7W5H
 | | The structure of trichobrasilenol synthase TaTC6 in complex with FsPP | | 分子名称: | GLYCEROL, MAGNESIUM ION, MALONATE ION, ... | | 著者 | Chen, C, Wang, T, Yang, Y, Zhang, L, Ko, T, Huang, J, Guo, R. | | 登録日 | 2021-11-30 | | 公開日 | 2022-08-31 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Structural insights into the cyclization of unusual brasilane-type sesquiterpenes.
Int.J.Biol.Macromol., 209, 2022
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7W5G
 | | The apo structure of trichobrasilenol synthase TaTC6 with the space group of orthorhombic | | 分子名称: | GLYCEROL, SULFATE ION, Terpene cyclase 6 | | 著者 | Chen, C, Wang, T, Yang, Y, Zhang, L, Ko, T, Huang, J, Guo, R. | | 登録日 | 2021-11-30 | | 公開日 | 2022-06-01 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural insights into the cyclization of unusual brasilane-type sesquiterpenes.
Int.J.Biol.Macromol., 209, 2022
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7W5F
 | | The apo structure of trichobrasilenol synthase TaTC6 with the space group of monoclinic | | 分子名称: | MAGNESIUM ION, Terpene cyclase 6 | | 著者 | Chen, C, Wang, T, Yang, Y, Zhang, L, Ko, T, Huang, J, Guo, R. | | 登録日 | 2021-11-30 | | 公開日 | 2022-06-01 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.53 Å) | | 主引用文献 | Structural insights into the cyclization of unusual brasilane-type sesquiterpenes.
Int.J.Biol.Macromol., 209, 2022
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7W5I
 | | The structure of trichobrasilenol synthase TaTC6 in complex with FPP-1 | | 分子名称: | FARNESYL DIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... | | 著者 | Chen, C, Wang, T, Yang, Y, Zhang, L, Ko, T, Huang, J, Guo, R. | | 登録日 | 2021-11-30 | | 公開日 | 2022-06-01 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | | 主引用文献 | Structural insights into the cyclization of unusual brasilane-type sesquiterpenes.
Int.J.Biol.Macromol., 209, 2022
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3JZI
 | | Crystal structure of biotin carboxylase from E. Coli in complex with benzimidazole series | | 分子名称: | 7-amino-2-[(2-chlorobenzyl)amino]-1-{[(1S,2S)-2-hydroxycycloheptyl]methyl}-1H-benzimidazole-5-carboxamide, Biotin carboxylase | | 著者 | Cheng, C, Shipps, G.W, Yang, Z, Sun, B, Kawahata, N, Soucy, K, Soriano, A, Orth, P, Xiao, L, Mann, P, Black, T. | | 登録日 | 2009-09-23 | | 公開日 | 2009-11-03 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | | 主引用文献 | Discovery and optimization of antibacterial AccC inhibitors.
Bioorg.Med.Chem.Lett., 19, 2009
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6NSL
 | | CRYSTAL STRUCTURE OF TYROSINE KINASE 2 JH2 (PSEUDO KINASE DOMAIN) COMPLEXED WITH Compound-6c AKA 6-((1-(4-CYANOPHENY L)-2-OXO-1,2-DIHYDRO-3-PYRIDINYL)AMINO)-N-CYCLOPROPYL-8-(M ETHYLAMINO)IMIDAZO[1,2-B]PYRIDAZINE-3-CARBOXAMIDE | | 分子名称: | 6-{[1-(4-cyanophenyl)-2-oxo-1,2-dihydropyridin-3-yl]amino}-N-cyclopropyl-8-(methylamino)imidazo[1,2-b]pyridazine-3-carboxamide, Non-receptor tyrosine-protein kinase TYK2, SULFATE ION | | 著者 | Muckelbauer, J.M, Khan, J.A. | | 登録日 | 2019-01-25 | | 公開日 | 2020-01-29 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Identification of Imidazo[1,2-b]pyridazine Derivatives as Potent, Selective, and Orally Active Tyk2 JH2 Inhibitors.
Acs Med.Chem.Lett., 10, 2019
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4ME2
 | | Crystal Structure of THA8 protein from Brachypodium distachyon | | 分子名称: | Uncharacterized protein | | 著者 | Ke, J, Chen, R.Z, Ban, T, Brunzelle, J.S, Gu, X, Melcher, K, Xu, H.E. | | 登録日 | 2013-08-24 | | 公開日 | 2013-10-30 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural basis for RNA recognition by a dimeric PPR-protein complex.
Nat.Struct.Mol.Biol., 20, 2013
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3F1Z
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4WK8
 | | FOXP3 forms a domain-swapped dimer to bridge DNA | | 分子名称: | DNA (5'-D(*AP*AP*CP*TP*AP*TP*GP*AP*AP*AP*CP*AP*AP*AP*TP*TP*TP*TP*CP*CP*T)-3'), DNA (5'-D(*TP*TP*AP*GP*GP*AP*AP*AP*AP*TP*TP*TP*GP*TP*TP*TP*CP*AP*TP*AP*G)-3'), Forkhead box protein P3 | | 著者 | Chen, Y, Chen, L. | | 登録日 | 2014-10-01 | | 公開日 | 2015-01-21 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (3.4006 Å) | | 主引用文献 | DNA binding by FOXP3 domain-swapped dimer suggests mechanisms of long-range chromosomal interactions.
Nucleic Acids Res., 43, 2015
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6CDP
 | | Vaccine-elicited HIV-1 neutralizing antibody vFP20.01 in complex with HIV-1 fusion peptide residue 512-519 | | 分子名称: | HIV-1 fusion peptide 512-519, SULFATE ION, vFP20.01 Fab heavy chain, ... | | 著者 | Xu, K, Liu, K, Kwong, P.D. | | 登録日 | 2018-02-08 | | 公開日 | 2018-05-16 | | 最終更新日 | 2018-06-20 | | 実験手法 | X-RAY DIFFRACTION (2.456 Å) | | 主引用文献 | Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1.
Nat. Med., 24, 2018
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7PQY
 | | Crystal structure of the receptor binding domain of SARS-CoV-2 Spike glycoprotein in complex with FI-3A Fab | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, FI-3A Fab heavy chain, FI-3A Fab light chain, ... | | 著者 | Zhou, D, Ren, J, Stuart, D. | | 登録日 | 2021-09-20 | | 公開日 | 2022-02-02 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structures and therapeutic potential of anti-RBD human monoclonal antibodies against SARS-CoV-2.
Theranostics, 12, 2022
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7PQZ
 | | Crystal structure of the receptor binding domain of SARS-CoV-2 Spike glycoprotein in complex with FI-3A and FD-11A Fabs | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FD-11A Fab heavy chain, FD-11A Fab light chain, ... | | 著者 | Zhou, D, Ren, J, Stuart, D.I. | | 登録日 | 2021-09-20 | | 公開日 | 2022-02-02 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structures and therapeutic potential of anti-RBD human monoclonal antibodies against SARS-CoV-2.
Theranostics, 12, 2022
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