1CZU
| REFINED STRUCTURES OF OXIDIZED FLAVODOXIN FROM ANACYSTIS NIDULANS | 分子名称: | FLAVIN MONONUCLEOTIDE, FLAVODOXIN | 著者 | Drennan, C.L, Pattridge, K.A, Weber, C.H, Metzger, A.L, Hoover, D.M, Ludwig, M.L. | 登録日 | 1999-09-07 | 公開日 | 1999-12-29 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Refined structures of oxidized flavodoxin from Anacystis nidulans. J.Mol.Biol., 294, 1999
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1D8G
| ULTRAHIGH RESOLUTION CRYSTAL STRUCTURE OF B-DNA DECAMER D(CCAGTACTGG) | 分子名称: | 5'-D(*CP*CP*AP*GP*TP*AP*CP*TP*GP*GP*)-3', CALCIUM ION | 著者 | Kielkopf, C.L, Ding, S, Kuhn, P, Rees, D.C. | 登録日 | 1999-10-23 | 公開日 | 2000-02-21 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (0.74 Å) | 主引用文献 | Conformational flexibility of B-DNA at 0.74 A resolution: d(CCAGTACTGG)(2). J.Mol.Biol., 296, 2000
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7CAM
| SARS-CoV-2 main protease (Mpro) apo structure (space group P212121) | 分子名称: | 3C-like proteinase | 著者 | Wang, Y.C, Yang, C.S, Hou, M.H, Tsai, C.L, Chou, Y.Z, Chen, Y. | 登録日 | 2020-06-09 | 公開日 | 2021-05-05 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Structural basis of SARS-CoV-2 main protease inhibition by a broad-spectrum anti-coronaviral drug. Am J Cancer Res, 10, 2020
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7CB7
| 1.7A resolution structure of SARS-CoV-2 main protease (Mpro) in complex with broad-spectrum coronavirus protease inhibitor GC376 | 分子名称: | (1R,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, (1S,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, 3C-like proteinase, ... | 著者 | Wang, Y.C, Yang, C.S, Hou, M.H, Tsai, C.L, Chou, Y.Z, Chen, Y, Hung, M.C. | 登録日 | 2020-06-10 | 公開日 | 2021-05-05 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | 主引用文献 | Structural basis of SARS-CoV-2 main protease inhibition by a broad-spectrum anti-coronaviral drug. Am J Cancer Res, 10, 2020
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1DEB
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7BH7
| Room temperature, serial X-ray structure of the ertapenem-derived acylenzyme of CTX-M-15 (10 min soak) collected on fixed target chips at Diamond Light Source I24 | 分子名称: | (2~{S},3~{R},4~{R})-3-[5-[(3-carboxyphenyl)carbamoyl]pyrrolidin-3-yl]sulfanyl-4-methyl-5-[(2~{S},3~{R})-3-oxidanyl-1-oxidanylidene-butan-2-yl]-3,4-dihydro-2~{H}-pyrrole-2-carboxylic acid, Beta-lactamase, CHLORIDE ION, ... | 著者 | Hinchliffe, P, Tooke, C.L, Butryn, A, Spencer, J. | 登録日 | 2021-01-10 | 公開日 | 2021-07-21 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | An on-demand, drop-on-drop method for studying enzyme catalysis by serial crystallography. Nat Commun, 12, 2021
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7BH6
| Room temperature, serial X-ray structure of CTX-M-15 collected on fixed target chips at Diamond Light Source I24 | 分子名称: | Beta-lactamase, CHLORIDE ION, SODIUM ION, ... | 著者 | Hinchliffe, P, Tooke, C.L, Butryn, A, Spencer, J. | 登録日 | 2021-01-10 | 公開日 | 2021-07-21 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | An on-demand, drop-on-drop method for studying enzyme catalysis by serial crystallography. Nat Commun, 12, 2021
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7BH4
| XFEL structure of apo CTX-M-15 after mixing for 0.7 sec with ertapenem using a piezoelectric injector (PolyPico) | 分子名称: | Beta-lactamase, SULFATE ION | 著者 | Hinchliffe, P, Tooke, C.L, Butryn, A, Spencer, J. | 登録日 | 2021-01-10 | 公開日 | 2021-07-21 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | An on-demand, drop-on-drop method for studying enzyme catalysis by serial crystallography. Nat Commun, 12, 2021
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7BH5
| XFEL structure of the ertapenem-derived CTX-M-15 acylenzyme after mixing for 2 sec using a piezoelectric injector (PolyPico) | 分子名称: | (2~{S},3~{R},4~{R})-3-[5-[(3-carboxyphenyl)carbamoyl]pyrrolidin-3-yl]sulfanyl-4-methyl-5-[(2~{S},3~{R})-3-oxidanyl-1-oxidanylidene-butan-2-yl]-3,4-dihydro-2~{H}-pyrrole-2-carboxylic acid, Beta-lactamase, CHLORIDE ION, ... | 著者 | Hinchliffe, P, Tooke, C.L, Butryn, A, Spencer, J. | 登録日 | 2021-01-10 | 公開日 | 2021-07-21 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | An on-demand, drop-on-drop method for studying enzyme catalysis by serial crystallography. Nat Commun, 12, 2021
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7BH3
| XFEL structure of CTX-M-15 resting state | 分子名称: | Beta-lactamase, CHLORIDE ION, SULFATE ION | 著者 | Hinchliffe, P, Tooke, C.L, Butryn, A, Spencer, J. | 登録日 | 2021-01-10 | 公開日 | 2021-07-21 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | An on-demand, drop-on-drop method for studying enzyme catalysis by serial crystallography. Nat Commun, 12, 2021
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5VO8
| X-ray crystal structure of a bacterial reiterative transcription complex of pyrG promoter | 分子名称: | DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*CP*TP*GP*AP*TP*GP*CP*AP*CP*C)-3'), DNA (5'-D(P*GP*GP*TP*GP*CP*AP*TP*CP*AP*GP*AP*GP*CP*CP*CP*AP*AP*AP*A)-3'), DNA-directed RNA polymerase subunit alpha, ... | 著者 | Murakami, K.S, Shin, Y, Turnbough Jr, C.L, Molodtsov, V. | 登録日 | 2017-05-02 | 公開日 | 2017-05-24 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | X-ray crystal structure of a reiterative transcription complex reveals an atypical RNA extension pathway. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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7BBT
| Structure of cytochrome c in complex with a p-benzyl-sulfonato-calix[8]arene-PEG pseudorotaxane | 分子名称: | 4-[[49,50,51,52,53,54,55,56-octahydroxy-11,17,23,29,35,41,47-heptakis[(4-sulfonatophenyl)methyl]-5-nonacyclo[43.3.1.13,7.19,13.115,19.121,25.127,31.133,37.139,43]hexapentaconta-1(49),3,5,7(56),9,11,13(55),15,17,19(54),21,23,25(53),27,29,31(52),33,35,37(51),39,41,43(50),45,47-tetracosaenyl]methyl]benzenesulfonate, Cytochrome c iso-1, HEME C, ... | 著者 | Mockler, N.M, Ramberg, K, Guagnini, F, Raston, C.L, Crowley, P.B. | 登録日 | 2020-12-18 | 公開日 | 2021-10-20 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (3.023 Å) | 主引用文献 | Noncovalent Protein-Pseudorotaxane Assembly Incorporating an Extended Arm Calix[8]arene with alpha-Helical Recognition Properties. Cryst.Growth Des., 21, 2021
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7EKZ
| Structural and functional insights into Hydra Actinoporin-Like Toxin 1 (HALT-1) | 分子名称: | FORMIC ACID, GLYCEROL, HALT-1 | 著者 | Ker, D.S, Sha, X.H, Jonet, M.A, Hwang, J.S, Ng, C.L. | 登録日 | 2021-04-07 | 公開日 | 2022-02-16 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | 主引用文献 | Structural and functional analysis of Hydra Actinoporin-Like Toxin 1 (HALT-1). Sci Rep, 11, 2021
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8GCI
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8GJM
| 17b10 fab in complex with full-length SARS-CoV-2 Spike G614 trimer | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Kwon, H.J, Zhang, J, Kosikova, M, Tang, W.C, Rodriguez, U.O, Peng, H.Q, Meseda, C.A, Pedro, C.L, Schmeisser, F, Lu, J.M, Zhou, B, Davis, C.T, Wentworth, D.E, Chen, W.H, Shriver, M.C, Pasetti, M.F, Weir, J.P, Chen, B, Xie, H. | 登録日 | 2023-03-16 | 公開日 | 2023-04-05 | 最終更新日 | 2024-10-16 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Distinct in vitro and in vivo neutralization profiles of monoclonal antibodies elicited by the receptor binding domain of the ancestral SARS-CoV-2. J Med Virol, 95, 2023
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8GCB
| Structure of RNF125 in complex with a UbcH5b~Ub conjugate | 分子名称: | E3 ubiquitin-protein ligase RNF125, Ubiquitin-conjugating enzyme E2 D2, ZINC ION | 著者 | Middleton, A.J, Day, C.L, Fokkens, T.J. | 登録日 | 2023-03-01 | 公開日 | 2023-07-19 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | 主引用文献 | Zinc finger 1 of the RING E3 ligase, RNF125, interacts with the E2 to enhance ubiquitylation. Structure, 31, 2023
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8GBQ
| Structure of RNF125 in complex with UbcH5b | 分子名称: | E3 ubiquitin-protein ligase RNF125, GLYCEROL, Ubiquitin-conjugating enzyme E2 D2, ... | 著者 | Middleton, A.J, Day, C.L, Fokkens, T.J. | 登録日 | 2023-02-27 | 公開日 | 2023-07-19 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | 主引用文献 | Zinc finger 1 of the RING E3 ligase, RNF125, interacts with the E2 to enhance ubiquitylation. Structure, 31, 2023
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8GUC
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8GJN
| 17B10 fab in complex with up-RBD of SARS-CoV-2 Spike G614 trimer | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of 17B10 Fab, Light chain of 17B10 Fab, ... | 著者 | Kwon, H.J, Zhang, J, Kosikova, M, Tang, W.C, Rodriguez, U.O, Peng, H.Q, Meseda, C.A, Pedro, C.L, Schmeisser, F, Lu, J.M, Zhou, B, Davis, C.T, Wentworth, D.E, Chen, W.H, Shriver, M.C, Pasetti, M.F, Weir, J.P, Chen, B, Xie, H. | 登録日 | 2023-03-16 | 公開日 | 2023-04-05 | 最終更新日 | 2023-04-19 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Distinct in vitro and in vivo neutralization profiles of monoclonal antibodies elicited by the receptor binding domain of the ancestral SARS-CoV-2. J Med Virol, 95, 2023
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8G57
| Structure of nucleosome-bound Sirtuin 6 deacetylase | 分子名称: | DNA strand 1, DNA strand 2, Histone H2A type 1-B/E, ... | 著者 | Chio, U.S, Rechiche, O, Bryll, A.R, Zhu, J, Feldman, J.L, Peterson, C.L, Tan, S, Armache, J.-P. | 登録日 | 2023-02-11 | 公開日 | 2023-04-26 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.07 Å) | 主引用文献 | Cryo-EM structure of the human Sirtuin 6-nucleosome complex. Sci Adv, 9, 2023
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8GKL
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8GKK
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8GKJ
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2L4V
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4FXX
| Structure of SF1 coiled-coil domain | 分子名称: | IMIDAZOLE, MALONATE ION, Splicing factor 1 | 著者 | Gupta, A, Bauer, W.J, Wang, W, Kielkopf, C.L. | 登録日 | 2012-07-03 | 公開日 | 2013-01-16 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.4801 Å) | 主引用文献 | Structure of Phosphorylated SF1 Bound to U2AF(65) in an Essential Splicing Factor Complex. Structure, 21, 2013
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