7BH4

XFEL structure of apo CTX-M-15 after mixing for 0.7 sec with ertapenem using a piezoelectric injector (PolyPico)

Summary for 7BH4

• Entry DOI: 10.2210/pdb7bh4/pdb
• Descriptor: Beta-lactamase, SULFATE ION (3 entities in total)
• Functional Keywords: serial crystallography, beta-lactamase, antibiotic, ertapenem, xfel, antimicrobial protein
• Biological source: Klebsiella pneumoniae
• Total number of polymer chains: 1
• Total formula weight: 28389.05

Authors

Hinchliffe, P.,Tooke, C.L.,Butryn, A.,Spencer, J. (deposition date: 2021-01-10, release date: 2021-07-21, Last modification date: 2024-01-31)

• Primary citation: Butryn, A.,Simon, P.S.,Aller, P.,Hinchliffe, P.,Massad, R.N.,Leen, G.,Tooke, C.L.,Bogacz, I.,Kim, I.S.,Bhowmick, A.,Brewster, A.S.,Devenish, N.E.,Brem, J.,Kamps, J.J.A.G.,Lang, P.A.,Rabe, P.,Axford, D.,Beale, J.H.,Davy, B.,Ebrahim, A.,Orlans, J.,Storm, S.L.S.,Zhou, T.,Owada, S.,Tanaka, R.,Tono, K.,Evans, G.,Owen, R.L.,Houle, F.A.,Sauter, N.K.,Schofield, C.J.,Spencer, J.,Yachandra, V.K.,Yano, J.,Kern, J.F.,Orville, A.M.; An on-demand, drop-on-drop method for studying enzyme catalysis by serial crystallography.; Nat Commun, 12:4461-4461, 2021; PubMed: 34294694; DOI: 10.1038/s41467-021-24757-7

Experimental method

X-RAY DIFFRACTION (1.55 Å)