4WBQ
| Crystal structure of the exonuclease domain of QIP (QDE-2 interacting protein) solved by native-SAD phasing. | 分子名称: | CALCIUM ION, QDE-2-interacting protein | 著者 | Boland, A, Weinert, T, Weichenrieder, O, Wang, M. | 登録日 | 2014-09-03 | 公開日 | 2014-12-10 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.693 Å) | 主引用文献 | Fast native-SAD phasing for routine macromolecular structure determination. Nat.Methods, 12, 2015
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4W99
| Apo-structure of the Y79F,W322E-double mutant of Etr1p | 分子名称: | Enoyl-[acyl-carrier-protein] reductase [NADPH, B-specific] 1, mitochondrial, ... | 著者 | Quade, N, Voegeli, B, Rosenthal, R, Erb, T.J. | 登録日 | 2014-08-27 | 公開日 | 2015-03-18 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The use of ene adducts to study and engineer enoyl-thioester reductases. Nat.Chem.Biol., 11, 2015
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4WBX
| Conserved hypothetical protein PF1771 from Pyrococcus furiosus solved by sulfur SAD using Swiss Light Source data | 分子名称: | 2-keto acid:ferredoxin oxidoreductase subunit alpha | 著者 | Weinert, T, Waltersperger, S, Olieric, V, Panepucci, E, Chen, L, Rose, J.P, Wang, M, Wang, B.C, Southeast Collaboratory for Structural Genomics (SECSG) | 登録日 | 2014-09-04 | 公開日 | 2014-12-10 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.301 Å) | 主引用文献 | Fast native-SAD phasing for routine macromolecular structure determination. Nat.Methods, 12, 2015
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4WAU
| Crystal structure of CENP-M solved by native-SAD phasing | 分子名称: | Centromere protein M | 著者 | Weinert, T, Basilico, F, Cecatiello, V, Pasqualato, S, Wang, M. | 登録日 | 2014-09-01 | 公開日 | 2014-12-10 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Fast native-SAD phasing for routine macromolecular structure determination. Nat.Methods, 12, 2015
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4WAB
| Crystal structure of mPGES1 solved by native-SAD phasing | 分子名称: | 2-[[2,6-bis(chloranyl)-3-[(2,2-dimethylpropanoylamino)methyl]phenyl]amino]-1-methyl-6-(2-methyl-2-oxidanyl-propoxy)-N-[2,2,2-tris(fluoranyl)ethyl]benzimidazole-5-carboxamide, GLUTATHIONE, Prostaglandin E synthase,Leukotriene C4 synthase | 著者 | Weinert, T, Li, D, Howe, N, Caffrey, M, Wang, M. | 登録日 | 2014-08-29 | 公開日 | 2014-12-10 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.704 Å) | 主引用文献 | Fast native-SAD phasing for routine macromolecular structure determination. Nat.Methods, 12, 2015
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4WAS
| STRUCTURE OF THE ETR1P/NADP/CROTONYL-COA COMPLEX | 分子名称: | CROTONYL COENZYME A, Enoyl-[acyl-carrier-protein] reductase [NADPH, B-specific] 1, ... | 著者 | Quade, N, Voegeli, B, Rosenthal, R, Capitani, G, Erb, T.J. | 登録日 | 2014-08-31 | 公開日 | 2015-03-18 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The use of ene adducts to study and engineer enoyl-thioester reductases. Nat.Chem.Biol., 11, 2015
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3IIF
| Crystal structure of the macro domain of human histone macroH2A1.1 in complex with ADP-ribose (form B) | 分子名称: | ADENOSINE-5-DIPHOSPHORIBOSE, Core histone macro-H2A.1, Isoform 1 | 著者 | Hothorn, M, Bortfeld, M, Ladurner, A.G, Scheffzek, K. | 登録日 | 2009-07-31 | 公開日 | 2009-08-18 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | A macrodomain-containing histone rearranges chromatin upon sensing PARP1 activation. Nat.Struct.Mol.Biol., 16, 2009
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3IID
| Crystal structure of the macro domain of human histone macroH2A1.1 in complex with ADP-ribose (form A) | 分子名称: | ADENOSINE-5-DIPHOSPHORIBOSE, Core histone macro-H2A.1, Isoform 1, ... | 著者 | Hothorn, M, Bortfeld, M, Ladurner, A.G, Scheffzek, K. | 登録日 | 2009-07-31 | 公開日 | 2009-08-18 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | A macrodomain-containing histone rearranges chromatin upon sensing PARP1 activation. Nat.Struct.Mol.Biol., 16, 2009
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5LCB
| In situ atomic-resolution structure of the baseplate antenna complex in Chlorobaculum tepidum obtained combining solid-state NMR spectroscopy, cryo electron microscopy and polarization spectroscopy | 分子名称: | BACTERIOCHLOROPHYLL A, Bacteriochlorophyll c-binding protein | 著者 | Nielsen, J.T, Kulminskaya, N.V, Bjerring, M, Linnanto, J.M, Ratsep, M, Pedersen, M, Lambrev, P.H, Dorogi, M, Garab, G, Thomsen, K, Jegerschold, C, Frigaard, N.U, Lindahl, M, Nielsen, N.C. | 登録日 | 2016-06-20 | 公開日 | 2016-07-27 | 最終更新日 | 2023-09-13 | 実験手法 | ELECTRON MICROSCOPY (26.5 Å), SOLID-STATE NMR | 主引用文献 | In situ high-resolution structure of the baseplate antenna complex in Chlorobaculum tepidum. Nat Commun, 7, 2016
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3CNR
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5HNQ
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7B52
| VAR2CSA full ectodomain | 分子名称: | Erythrocyte membrane protein 1 | 著者 | Wang, K.T, Gourdon, P.E, Dagil, R, Salanti, A. | 登録日 | 2020-12-03 | 公開日 | 2021-04-21 | 最終更新日 | 2022-05-25 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Cryo-EM reveals the architecture of placental malaria VAR2CSA and provides molecular insight into chondroitin sulfate binding. Nat Commun, 12, 2021
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7B62
| Crystal structure of SARS-CoV-2 spike protein N-terminal domain in complex with biliverdin | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, BILIVERDINE IX ALPHA, DI(HYDROXYETHYL)ETHER, ... | 著者 | Pye, V.E, Rosa, A, Roustan, C, Cherepanov, P. | 登録日 | 2020-12-07 | 公開日 | 2021-04-28 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | SARS-CoV-2 can recruit a heme metabolite to evade antibody immunity. Sci Adv, 7, 2021
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7B54
| VAR2CSA full ectodomain in present of plCS, DBL1-DBL4 | 分子名称: | VAR2CSA in presence of plCS, DBl1-DBL4,Erythrocyte membrane protein 1 | 著者 | Wang, K.T, Dagil, R, Gourdon, P.E, Salanti, A. | 登録日 | 2020-12-03 | 公開日 | 2021-06-02 | 最終更新日 | 2022-05-25 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Cryo-EM reveals the architecture of placental malaria VAR2CSA and provides molecular insight into chondroitin sulfate binding. Nat Commun, 12, 2021
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5HN2
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5HNJ
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8R8E
| DYRK1a in Complex with 2-Cyclopentyl-7-iodo-1H-indole-3-carbonitrile | 分子名称: | 1,2-ETHANEDIOL, 2-cyclopentyl-7-iodanyl-1~{H}-indole-3-carbonitrile, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | 著者 | Stahlecker, J, Dammann, M, Stehle, T, Boeckler, F.M. | 登録日 | 2023-11-29 | 公開日 | 2024-09-25 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | 主引用文献 | Halogen Bonding on Water─A Drop in the Ocean? J Chem Theory Comput, 2024
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4EJX
| Structure of ceruloplasmin-myeloperoxidase complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, COPPER (II) ION, Ceruloplasmin, ... | 著者 | Samygina, V.R, Sokolov, A.V, Bourenkov, G, Vasilyev, V.B, Bartunik, H. | 登録日 | 2012-04-07 | 公開日 | 2013-04-10 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (4.69 Å) | 主引用文献 | Ceruloplasmin: macromolecular assemblies with iron-containing acute phase proteins. Plos One, 8, 2013
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4EZM
| Crystal structure of the human IgE-Fc(epsilon)3-4 bound to its B cell receptor derCD23 | 分子名称: | Ig epsilon chain C region, Low affinity immunoglobulin epsilon Fc receptor, alpha-D-mannopyranose, ... | 著者 | Dhaliwal, B, Yuan, D, Sutton, B.J. | 登録日 | 2012-05-03 | 公開日 | 2012-07-18 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Crystal structure of IgE bound to its B-cell receptor CD23 reveals a mechanism of reciprocal allosteric inhibition with high affinity receptor Fc{varepsilon}RI. Proc.Natl.Acad.Sci.USA, 109, 2012
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4ENZ
| Structure of human ceruloplasmin at 2.6 A resolution | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, COPPER (II) ION, ... | 著者 | Samygina, V.R, Sokolov, A.V, Bourenkov, G, Vasilyev, V.B, Bartunik, H. | 登録日 | 2012-04-13 | 公開日 | 2013-04-17 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Ceruloplasmin: macromolecular assemblies with iron-containing acute phase proteins. Plos One, 8, 2013
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7QAR
| Serial crystallography structure of cofactor-free urate oxidase in complex with the 5-peroxo derivative of 9-methyl uric acid at room temperature | 分子名称: | (5S)-5-(dioxidanyl)-9-methyl-7H-purine-2,6,8-trione, Uricase | 著者 | Bui, S, Catapano, L, Zielinski, K, Yefanov, O, Murshudov, G.N, Oberthuer, D, Steiner, R.A. | 登録日 | 2021-11-17 | 公開日 | 2023-04-26 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Rapid and efficient room-temperature serial synchrotron crystallography using the CFEL TapeDrive. Iucrj, 9, 2022
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7R9C
| Cocrystal of BRD4(D1) with N,N-dimethyl-2-[(3R)-3-(5-{2-[2-methyl-5-(propan-2-yl)phenoxy]pyrimidin-4-yl}-4-[4-(trifluoromethyl)phenyl]-1H-imidazol-1-yl)pyrrolidin-1-yl]ethan-1-amine | 分子名称: | 1,2-ETHANEDIOL, Bromodomain-containing protein 4, CHLORIDE ION, ... | 著者 | Cui, H, Shi, K, Aihara, H, Pomerantz, W.C.K. | 登録日 | 2021-06-29 | 公開日 | 2022-01-19 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | A Structure-based Design Approach for Generating High Affinity BRD4 D1-Selective Chemical Probes. J.Med.Chem., 65, 2022
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7RXS
| Crystal of BRD4(D1) with 2-[(3S)-3-{5-[2-(3,5-dimethylphenoxy)pyrimidin-4-yl]-4-(4-iodophenyl)-1H-imidazol-1-yl}pyrrolidin-1-yl]ethan-1-amine | 分子名称: | 1,2-ETHANEDIOL, 2-[(3S)-3-{5-[2-(3,5-dimethylphenoxy)pyrimidin-4-yl]-4-(4-iodophenyl)-1H-imidazol-1-yl}pyrrolidin-1-yl]ethan-1-amine, Bromodomain-containing protein 4 | 著者 | Cui, H, Johnson, J.A, Shi, K, Aihara, H, Pomerantz, W.C.K. | 登録日 | 2021-08-23 | 公開日 | 2022-01-19 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | 主引用文献 | A Structure-based Design Approach for Generating High Affinity BRD4 D1-Selective Chemical Probes. J.Med.Chem., 65, 2022
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7RXT
| Crystal of BRD4(D1) with 2-[(3R)-3-{5-[2-(3,5-dimethylphenoxy)pyrimidin-4-yl]-4-(4-iodophenyl)-1H-imidazol-1-yl}pyrrolidin-1-yl]ethan-1-amine | 分子名称: | 2-[(3R)-3-{5-[2-(3,5-dimethylphenoxy)pyrimidin-4-yl]-4-(4-iodophenyl)-1H-imidazol-1-yl}pyrrolidin-1-yl]ethan-1-amine, Bromodomain-containing protein 4 | 著者 | Cui, H, Johnson, J.A, Shi, K, Aihara, H, Pomerantz, W.C.K. | 登録日 | 2021-08-23 | 公開日 | 2022-01-19 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | 主引用文献 | A Structure-based Design Approach for Generating High Affinity BRD4 D1-Selective Chemical Probes. J.Med.Chem., 65, 2022
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7RXR
| Crystal Structure of BRD4(D1) with 4-[4-(4-bromophenyl)-1-(piperidin-4-yl)-1H-imidazol-5-yl]-N-(3,5-dimethylphenyl)pyrimidin-2-amine | 分子名称: | 1,2-ETHANEDIOL, 4-[4-(4-bromophenyl)-1-(piperidin-4-yl)-1H-imidazol-5-yl]-N-(3,5-dimethylphenyl)pyrimidin-2-amine, Bromodomain-containing protein 4 | 著者 | Cui, H, Johnson, J.A, Shi, K, Aihara, H, Pomerantz, W.C.K. | 登録日 | 2021-08-23 | 公開日 | 2022-01-19 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.41 Å) | 主引用文献 | A Structure-based Design Approach for Generating High Affinity BRD4 D1-Selective Chemical Probes. J.Med.Chem., 65, 2022
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