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1YDS
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Structure of CAMP-dependent protein kinase, alpha-catalytic subunit in complex with H8 protein kinase inhibitor [N-(2-methylamino)ethyl]-5-isoquinolinesulfonamide
分子名称: C-AMP-DEPENDENT PROTEIN KINASE, N-[2-(METHYLAMINO)ETHYL]-5-ISOQUINOLINESULFONAMIDE, PROTEIN KINASE INHIBITOR PEPTIDE
著者Engh, R.A, Girod, A, Kinzel, V, Huber, R, Bossemeyer, D.
登録日1996-07-24
公開日1997-04-01
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structures of catalytic subunit of cAMP-dependent protein kinase in complex with isoquinolinesulfonyl protein kinase inhibitors H7, H8, and H89. Structural implications for selectivity.
J.Biol.Chem., 271, 1996
1PPE
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THE REFINED 2.0 ANGSTROMS X-RAY CRYSTAL STRUCTURE OF THE COMPLEX FORMED BETWEEN BOVINE BETA-TRYPSIN AND CMTI-I, A TRYPSIN INHIBITOR FROM SQUASH SEEDS (CUCURBITA MAXIMA): TOPOLOGICAL SIMILARITY OF THE SQUASH SEED INHIBITORS WITH THE CARBOXYPEPTIDASE A INHIBITOR FROM POTATOES
分子名称: TRYPSIN, TRYPSIN INHIBITOR CMTI-I
著者Bode, W, Huber, R.
登録日1991-10-24
公開日1994-01-31
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The refined 2.0 A X-ray crystal structure of the complex formed between bovine beta-trypsin and CMTI-I, a trypsin inhibitor from squash seeds (Cucurbita maxima). Topological similarity of the squash seed inhibitors with the carboxypeptidase A inhibitor from potatoes
FEBS Lett., 242, 1989
1MVN
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PPC decarboxylase mutant C175S complexed with pantothenoylaminoethenethiol
分子名称: 2,4-DIHYDROXY-N-[2-(2-MERCAPTO-VINYLCARBAMOYL)-ETHYL]-3,3-DIMETHYL-BUTYRAMIDE, FLAVIN MONONUCLEOTIDE, PPC decarboxylase AtHAL3a
著者Steinbacher, S, Hernandez-Acosta, P, Bieseler, B, Blaesse, M, Huber, R, Culianez-Macia, F.A, Kupke, T.
登録日2002-09-26
公開日2003-03-04
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Crystal Structure of the Plant PPC Decarboxylase AtHAL3a Complexed with an Ene-thiol Reaction Intermediate
J.Mol.Biol., 327, 2003
1CTS
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CRYSTALLOGRAPHIC REFINEMENT AND ATOMIC MODELS OF TWO DIFFERENT FORMS OF CITRATE SYNTHASE AT 2.7 AND 1.7 ANGSTROMS RESOLUTION
分子名称: CITRATE SYNTHASE, CITRIC ACID
著者Remington, S, Wiegand, G, Huber, R.
登録日1984-01-27
公開日1984-07-20
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystallographic refinement and atomic models of two different forms of citrate synthase at 2.7 and 1.7 A resolution.
J.Mol.Biol., 158, 1982
1N6E
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BU of 1n6e by Molmil
tricorn protease in complex with a tridecapeptide chloromethyl ketone derivative
分子名称: DQTQKAAAELTFF, Tricorn protease
著者Kim, J.-S, Groll, M, Huber, R, Brandstetter, H.
登録日2002-11-10
公開日2002-12-30
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Navigation Inside a Protease: Substrate Selection and Product Exit in the Tricorn Protease from Thermoplasma acidophilum
J.Mol.Biol., 324, 2002
1ILU
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BU of 1ilu by Molmil
X-RAY CRYSTAL STRUCTURE THE TWO SITE-SPECIFIC MUTANTS ILE7SER AND PHE110SER OF AZURIN FROM PSEUDOMONAS AERUGINOSA
分子名称: AZURIN, COPPER (II) ION
著者Hammann, C, Nar, H, Huber, R, Messerschmidt, A.
登録日1995-10-12
公開日1996-03-08
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献X-ray crystal structure of the two site-specific mutants Ile7Ser and Phe110Ser of azurin from Pseudomonas aeruginosa.
J.Mol.Biol., 255, 1996
1N6D
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Tricorn protease in complex with tetrapeptide chloromethyl ketone derivative
分子名称: DECANE, RVRK, Tricorn protease
著者Kim, J.-S, Groll, M, Huber, R, Brandstetter, H.
登録日2002-11-10
公開日2002-12-30
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Navigation Inside a Protease: Substrate Selection and Product Exit in the Tricorn Protease from Thermoplasma acidophilum
J.Mol.Biol., 324, 2002
1ILS
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BU of 1ils by Molmil
X-RAY CRYSTAL STRUCTURE THE TWO SITE-SPECIFIC MUTANTS ILE7SER AND PHE110SER OF AZURIN FROM PSEUDOMONAS AERUGINOSA
分子名称: AZURIN, COPPER (II) ION, NITRATE ION
著者Hammann, C, Nar, H, Huber, R, Messerschmidt, A.
登録日1995-10-12
公開日1996-03-08
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献X-ray crystal structure of the two site-specific mutants Ile7Ser and Phe110Ser of azurin from Pseudomonas aeruginosa.
J.Mol.Biol., 255, 1996
1JDX
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BU of 1jdx by Molmil
CRYSTAL STRUCTURE OF HUMAN L-ARGININE:GLYCINE AMIDINOTRANSFERASE IN COMPLEX WITH L-NORVALINE
分子名称: NORVALINE, PROTEIN (L-ARGININE:GLYCINE AMIDINOTRANSFERASE)
著者Fritsche, E, Humm, A, Huber, R.
登録日1998-10-12
公開日1999-02-09
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The ligand-induced structural changes of human L-Arginine:Glycine amidinotransferase. A mutational and crystallographic study.
J.Biol.Chem., 274, 1999
1MVL
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PPC decarboxylase mutant C175S
分子名称: FLAVIN MONONUCLEOTIDE, PPC decarboxylase AtHAL3a
著者Steinbacher, S, Hernandez-Acosta, P, Bieseler, B, Blaesse, M, Huber, R, Culianez-Macia, F.A, Kupke, T.
登録日2002-09-26
公開日2003-03-04
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of the Plant PPC Decarboxylase AtHAL3a Complexed with an Ene-thiol Reaction Intermediate
J.Mol.Biol., 327, 2003
1DX5
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BU of 1dx5 by Molmil
Crystal structure of the thrombin-thrombomodulin complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, FORMIC ACID, ...
著者Fuentes-Prior, P, Iwanaga, Y, Huber, R, Pagila, R, Rumennik, G, Seto, M, Morser, J, Light, D.R, Bode, W.
登録日1999-12-20
公開日2000-04-10
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural Basis for the Anticoagulant Activity of the Thrombin-Thrombomodulin Complex
Nature, 404, 2000
1CL1
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CYSTATHIONINE BETA-LYASE (CBL) FROM ESCHERICHIA COLI
分子名称: BICARBONATE ION, CYSTATHIONINE BETA-LYASE
著者Clausen, T, Huber, R, Messerschmidt, A.
登録日1997-09-02
公開日1998-09-09
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Crystal structure of the pyridoxal-5'-phosphate dependent cystathionine beta-lyase from Escherichia coli at 1.83 A.
J.Mol.Biol., 262, 1996
1CLW
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TAILSPIKE PROTEIN FROM PHAGE P22, V331A MUTANT
分子名称: TAILSPIKE PROTEIN
著者Steinbacher, S, Baxa, U, Weintraub, A, Huber, R, Seckler, R.
登録日1999-05-04
公開日1999-11-05
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Mutations improving the folding of phage P22 tailspike protein affect its receptor binding activity.
J.Mol.Biol., 293, 1999
1DHP
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BU of 1dhp by Molmil
DIHYDRODIPICOLINATE SYNTHASE
分子名称: DIHYDRODIPICOLINATE SYNTHASE, POTASSIUM ION
著者Mirwaldt, C, Korndoerfer, I, Huber, R.
登録日1995-02-09
公開日1997-02-12
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The crystal structure of dihydrodipicolinate synthase from Escherichia coli at 2.5 A resolution.
J.Mol.Biol., 246, 1995
2H6T
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BU of 2h6t by Molmil
Secreted aspartic proteinase (Sap) 3 from Candida albicans complexed with pepstatin A
分子名称: Candidapepsin-3, ZINC ION, pepstatin A
著者Ruge, E, Borelli, C, Maskos, K, Huber, R.
登録日2006-06-01
公開日2007-06-12
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The crystal structure of the secreted aspartic proteinase 3 from Candida albicans and its complex with pepstatin A.
Proteins, 68, 2007
2H6S
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Secreted aspartic proteinase (Sap) 3 from Candida albicans
分子名称: Candidapepsin-3, ZINC ION
著者Ruge, E, Borelli, C, Maskos, K, Huber, R.
登録日2006-06-01
公開日2007-06-12
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The crystal structure of the secreted aspartic proteinase 3 from Candida albicans and its complex with pepstatin A.
Proteins, 68, 2007
1U9L
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BU of 1u9l by Molmil
Structural basis for a NusA- protein N interaction
分子名称: GOLD ION, Lambda N, Transcription elongation protein nusA
著者Bonin, I, Muehlberger, R, Bourenkov, G.P, Huber, R, Bacher, A, Richter, G, Wahl, M.C.
登録日2004-08-10
公開日2004-08-31
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis for the interaction of Escherichia coli NusA with protein N of phage lambda
Proc.Natl.Acad.Sci.Usa, 101, 2004
1CHM
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ENZYMATIC MECHANISM OF CREATINE AMIDINOHYDROLASE AS DEDUCED FROM CRYSTAL STRUCTURES
分子名称: CARBAMOYL SARCOSINE, CREATINE AMIDINOHYDROLASE
著者Hoeffken, H.W, Knof, S.H, Bartlett, P.A, Huber, R, Moellering, H, Schumacher, G.
登録日1993-07-19
公開日1994-04-30
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Enzymatic mechanism of creatine amidinohydrolase as deduced from crystal structures.
J.Mol.Biol., 214, 1990
1CL2
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CYSTATHIONINE BETA-LYASE (CBL) FROM ESCHERICHIA COLI IN COMPLEX WITH AMINOETHOXYVINYLGLYCINE
分子名称: (2E,3E)-4-(2-aminoethoxy)-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)imino]but-3-enoic acid, CYSTATHIONINE BETA-LYASE
著者Clausen, T, Huber, R, Messerschmidt, A.
登録日1997-09-04
公開日1998-09-09
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Slow-binding inhibition of Escherichia coli cystathionine beta-lyase by L-aminoethoxyvinylglycine: a kinetic and X-ray study.
Biochemistry, 36, 1997
1RVV
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SYNTHASE/RIBOFLAVIN SYNTHASE COMPLEX OF BACILLUS SUBTILIS
分子名称: 5-NITRO-6-RIBITYL-AMINO-2,4(1H,3H)-PYRIMIDINEDIONE, PHOSPHATE ION, RIBOFLAVIN SYNTHASE
著者Ritsert, K, Huber, R, Turk, D, Ladenstein, R, Schmidt-Baese, K, Bacher, A.
登録日1995-10-25
公開日1996-12-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Studies on the lumazine synthase/riboflavin synthase complex of Bacillus subtilis: crystal structure analysis of reconstituted, icosahedral beta-subunit capsids with bound substrate analogue inhibitor at 2.4 A resolution.
J.Mol.Biol., 253, 1995
1N6F
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tricorn protease in complex with Z-Phe-diketo-Arg-Glu-Phe
分子名称: 4-[2-(3-BENZYLOXYCARBONYLAMINO-4-CYCLOHEXYL-1-HYDROXY-2-OXO-BUTYLAMINO)-5-GUANIDINO-PENTANOYLAMINO]-4-(1-CARBOXY-2-CYCLOHEXYL-ETHYLCARBAMOYL)-BUTYRIC ACID, tricorn protease
著者Kim, J.-S, Groll, M, Huber, R, Brandstetter, H.
登録日2002-11-10
公開日2002-12-30
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Navigation Inside a Protease: Substrate Selection and Product Exit in the Tricorn Protease from Thermoplasma acidophilum
J.Mol.Biol., 324, 2002
1TSP
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CRYSTAL STRUCTURE OF P22 TAILSPIKE PROTEIN: INTERDIGITATED SUBUNITS IN A THERMOSTABLE TRIMER
分子名称: TAILSPIKE-PROTEIN
著者Steinbacher, S, Seckler, R, Miller, S, Steipe, B, Huber, R, Reinemer, P.
登録日1994-06-16
公開日1995-09-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of P22 tailspike protein: interdigitated subunits in a thermostable trimer.
Science, 265, 1994
1NPS
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CRYSTAL STRUCTURE OF N-TERMINAL DOMAIN OF PROTEIN S
分子名称: CALCIUM ION, DEVELOPMENT-SPECIFIC PROTEIN S
著者Wenk, M, Baumgartner, R, Mayer, E.M, Huber, R, Holak, T.A, Jaenicke, R.
登録日1999-02-01
公開日2000-02-04
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The domains of protein S from Myxococcus xanthus: structure, stability and interactions.
J.Mol.Biol., 286, 1999
2F9N
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Crystal Structure of the Recombinant Human Alpha I Tryptase Mutant K192Q/D216G in Complex with Leupeptin
分子名称: (R,R)-2,3-BUTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Leupeptin, ...
著者Rohr, K.B, Selwood, T, Marquardt, U, Huber, R, Schechter, N.M, Bode, W, Than, M.E.
登録日2005-12-06
公開日2006-01-31
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献X-ray Structures of Free and Leupeptin-complexed Human alpha I-Tryptase Mutants: Indication for an alpha to beta-Tryptase Transition
J.Mol.Biol., 357, 2005
1BLI
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BACILLUS LICHENIFORMIS ALPHA-AMYLASE
分子名称: ALPHA-AMYLASE, CALCIUM ION, SODIUM ION
著者Machius, M, Declerck, N, Huber, R, Wiegand, G.
登録日1998-01-07
公開日1999-03-23
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Activation of Bacillus licheniformis alpha-amylase through a disorder-->order transition of the substrate-binding site mediated by a calcium-sodium-calcium metal triad.
Structure, 6, 1998

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