2WLS
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![BU of 2wls by Molmil](/molmil-images/mine/2wls) | Crystal structure of Mus musculus Acetylcholinesterase in complex with AMTS13 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETYLCHOLINESTERASE, DI(HYDROXYETHYL)ETHER, ... | 著者 | Pang, Y.P, Ekstrom, F, Polsinelli, G.A, Gao, Y, Rana, S, Hua, D.H, Andersson, B, Andersson, P.O, Peng, L, Singh, S.K, Mishra, R.K, Zhu, K.Y, Fallon, A.M, Ragsdale, D.W, Brimijoin, S. | 登録日 | 2009-06-25 | 公開日 | 2009-09-08 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Selective and Irreversible Inhibitors of Mosquito Acetylcholinesterases for Controlling Malaria and Other Mosquito-Borne Diseases. Plos One, 4, 2009
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6TGI
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![BU of 6tgi by Molmil](/molmil-images/mine/6tgi) | Crystal structure of VIM-2 in complex with triazole-based inhibitor OP24 | 分子名称: | 5-(4-chloranyl-1,5-dimethyl-pyrazol-3-yl)-4-ethyl-1,2,4-triazole-3-thiol, FORMIC ACID, Vim-1, ... | 著者 | Maso, L, Spirakis, F, Santucci, M, Simon, C, Docquier, J.D, Cruciani, G, Costi, M.P, Tondi, D, Cendron, L. | 登録日 | 2019-11-15 | 公開日 | 2020-10-14 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Virtual screening identifies broad-spectrum beta-lactamase inhibitors with activity on clinically relevant serine- and metallo-carbapenemases. Sci Rep, 10, 2020
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3KAV
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![BU of 3kav by Molmil](/molmil-images/mine/3kav) | Crystal Structure of THE MUTANT (L80M) PA2107 PROTEIN from Pseudomonas aeruginosa, Northeast Structural Genomics Consortium Target PaR198 | 分子名称: | uncharacterized protein PA2107 | 著者 | Forouhar, F, Neely, H, Seetharaman, J, Sahdev, S, Xiao, R, Ciccosanti, C, Foote, E.L, Zhao, L, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2009-10-19 | 公開日 | 2009-10-27 | 最終更新日 | 2021-10-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Northeast Structural Genomics Consortium Target PaR198 To be Published
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6JSJ
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6JUF
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![BU of 6juf by Molmil](/molmil-images/mine/6juf) | SspB crystal structure | 分子名称: | SspB protein | 著者 | Liqiong, L, Yubing, Z. | 登録日 | 2019-04-13 | 公開日 | 2020-03-25 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.587 Å) | 主引用文献 | SspABCD-SspE is a phosphorothioation-sensing bacterial defence system with broad anti-phage activities. Nat Microbiol, 5, 2020
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6TI7
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![BU of 6ti7 by Molmil](/molmil-images/mine/6ti7) | Mixing Abeta(1-40) and Abeta(1-42) peptides generates unique amyloid fibrils | 分子名称: | Amyloid-beta precursor protein | 著者 | Cerofolini, L, Ravera, E, Bologna, S, Wiglenda, T, Boddrich, A, Purfurst, B, Benilova, A, Korsak, M, Gallo, G, Rizzo, D, Gonnelli, L, Fragai, M, De Strooper, B, Wanker, E.E, Luchinat, C. | 登録日 | 2019-11-21 | 公開日 | 2020-07-22 | 最終更新日 | 2024-06-19 | 実験手法 | SOLID-STATE NMR | 主引用文献 | Mixing A beta (1-40) and A beta (1-42) peptides generates unique amyloid fibrils. Chem.Commun.(Camb.), 56, 2020
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3JWD
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![BU of 3jwd by Molmil](/molmil-images/mine/3jwd) | Structure of HIV-1 gp120 with gp41-Interactive Region: Layered Architecture and Basis of Conformational Mobility | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, FAB 48D HEAVY CHAIN, FAB 48D LIGHT CHAIN, ... | 著者 | Pancera, M, Majeed, S, Ban, Y.A, Chen, L, Huang, C.C, Kong, L, Kwon, Y.D, Stuckey, J, Zhou, T, Robinson, J.E, Schief, W.R, Sodroski, J, Wyatt, R, Kwong, P.D. | 登録日 | 2009-09-18 | 公開日 | 2009-12-29 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | 主引用文献 | Structure of HIV-1 gp120 with gp41-interactive region reveals layered envelope architecture and basis of conformational mobility. Proc.Natl.Acad.Sci.USA, 107, 2010
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1XZY
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![BU of 1xzy by Molmil](/molmil-images/mine/1xzy) | Solution structure of the P30-trans form of Alpha Hemoglobin Stabilizing Protein (AHSP) | 分子名称: | Alpha-hemoglobin stabilizing protein | 著者 | Gell, D.A, Feng, L, Zhou, S, Kong, Y, Lee, C, Weiss, M.J, Shi, Y, Mackay, J.P. | 登録日 | 2004-11-12 | 公開日 | 2004-12-21 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Molecular mechanism of AHSP-mediated stabilization of alpha-hemoglobin Cell(Cambridge,Mass.), 119, 2004
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6TS9
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![BU of 6ts9 by Molmil](/molmil-images/mine/6ts9) | Crystal structure of GES-5 carbapenemase | 分子名称: | 1,2-ETHANEDIOL, BROMIDE ION, Beta-lactamase, ... | 著者 | Maso, L, Tondi, D, Klein, R, Montanari, M, Bellio, C, Celenza, G, Brenk, R, Cendron, L. | 登録日 | 2019-12-20 | 公開日 | 2020-03-04 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Targeting the Class A Carbapenemase GES-5 via Virtual Screening. Biomolecules, 10, 2020
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3K9R
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![BU of 3k9r by Molmil](/molmil-images/mine/3k9r) | X-ray structure of the Rhodanese-like domain of the Alr3790 protein from Anabaena sp. Northeast Structural Genomics Consortium Target NsR437c. | 分子名称: | Alr3790 protein | 著者 | Vorobiev, S, Chen, Y, Seetharaman, J, Maglaqui, M, Ciccosanti, C, Mao, L, Xiao, R, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2009-10-16 | 公開日 | 2009-10-27 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | X-ray structure of the Rhodanese-like domain of the Alr3790 protein from Anabaena sp. To be Published
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7LKI
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7JXV
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![BU of 7jxv by Molmil](/molmil-images/mine/7jxv) | ANTH domain of CALM (clathrin-assembly lymphoid myeloid leukemia protein) bound to ubiquitin | 分子名称: | Phosphatidylinositol-binding clathrin assembly protein, Ubiquitin | 著者 | Pashkova, N, Gakhar, L, Schnicker, N.J, Piper, R.C. | 登録日 | 2020-08-28 | 公開日 | 2021-08-04 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | ANTH domains within CALM, HIP1R, and Sla2 recognize ubiquitin internalization signals. Elife, 10, 2021
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5ZK1
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![BU of 5zk1 by Molmil](/molmil-images/mine/5zk1) | Crystal Structure of the CRTC2(SeMet)-CREB-CRE complex | 分子名称: | CREB-regulated transcription coactivator 2, Cyclic AMP-responsive element-binding protein 1, DNA (5'-D(*CP*TP*TP*GP*GP*CP*TP*GP*AP*CP*GP*TP*CP*AP*GP*CP*CP*AP*AP*G)-3'), ... | 著者 | Xiang, S, Zhai, L, Valencia-Swain, J. | 登録日 | 2018-03-22 | 公開日 | 2018-06-20 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | 主引用文献 | Structural Insights into the CRTC2-CREB Complex Assembly on CRE. J. Mol. Biol., 430, 2018
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5ZKO
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![BU of 5zko by Molmil](/molmil-images/mine/5zko) | Crystal structure of the CRTC2-CREB-CRE complex | 分子名称: | CREB-regulated transcription coactivator 2, Cyclic AMP-responsive element-binding protein 1, DNA (5'-D(*CP*TP*TP*GP*GP*CP*TP*GP*AP*CP*GP*TP*CP*AP*GP*CP*CP*AP*AP*G)-3') | 著者 | Xiang, S, Zhai, L, Valecia-Swain, J. | 登録日 | 2018-03-24 | 公開日 | 2018-06-20 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | 主引用文献 | Structural Insights into the CRTC2-CREB Complex Assembly on CRE. J. Mol. Biol., 430, 2018
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3JYH
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![BU of 3jyh by Molmil](/molmil-images/mine/3jyh) | Human dipeptidyl peptidase DPP7 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Dipeptidyl-peptidase 2, ... | 著者 | Dobrovetsky, E, Dong, A, Seitova, A, Crombett, L, Paganon, S, Cossar, D, Edwards, A.M, Arrowsmith, C.H, Bountra, C, Weigelt, J, Hassel, A, Shewchuk, L, Bochkarev, A, Structural Genomics Consortium (SGC) | 登録日 | 2009-09-21 | 公開日 | 2009-10-13 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | 主引用文献 | Human dipeptidyl peptidase DPP7 To be Published
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3JBL
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![BU of 3jbl by Molmil](/molmil-images/mine/3jbl) | Cryo-EM Structure of the Activated NAIP2/NLRC4 Inflammasome Reveals Nucleated Polymerization | 分子名称: | NLR family CARD domain-containing protein 4 | 著者 | Zhang, L, Chen, S, Ruan, J, Wu, J, Tong, A.B, Yin, Q, Li, Y, David, L, Lu, A, Wang, W.L, Marks, C, Ouyang, Q, Zhang, X, Mao, Y, Wu, H. | 登録日 | 2015-09-05 | 公開日 | 2015-10-21 | 最終更新日 | 2018-07-18 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Cryo-EM structure of the activated NAIP2-NLRC4 inflammasome reveals nucleated polymerization. Science, 350, 2015
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6SJX
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![BU of 6sjx by Molmil](/molmil-images/mine/6sjx) | Precursor structure of the self-processing module of iron-regulated FrpC of N. Meningitidis with calcium ions | 分子名称: | CALCIUM ION, Iron-regulated protein FrpC | 著者 | Kuban, V, Macek, P, Hritz, J, Nechvatalova, K, Nedbalcova, K, Faldyna, M, Zidek, L, Bumba, L. | 登録日 | 2019-08-14 | 公開日 | 2020-02-26 | 最終更新日 | 2024-06-19 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural Basis of Ca 2+ -Dependent Self-Processing Activity of Repeat-in-Toxin Proteins. Mbio, 11, 2020
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3JVN
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![BU of 3jvn by Molmil](/molmil-images/mine/3jvn) | Crystal Structure of the acetyltransferase VF_1542 from Vibrio fischeri, Northeast Structural Genomics Consortium Target VfR136 | 分子名称: | Acetyltransferase, SULFATE ION | 著者 | Forouhar, F, Neely, H, Seetharaman, J, Mao, M, Xiao, R, Ciccosanti, C, Zhao, L, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2009-09-17 | 公開日 | 2009-09-29 | 最終更新日 | 2019-08-07 | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | 主引用文献 | Northeast Structural Genomics Consortium Target VfR136 To be Published
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3JVC
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![BU of 3jvc by Molmil](/molmil-images/mine/3jvc) | Crystal Structure of the Lipoprotein_17 domain from Q9PRA0_UREPA protein of Ureaplasma parvum. Northeast Structural Genomics Consortium Target UuR17a. | 分子名称: | Conserved hypothetical membrane lipoprotein | 著者 | Vorobiev, S, Neely, H, Lee, D, Ciccosanti, C, Mao, L, Xiao, R, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2009-09-16 | 公開日 | 2009-09-29 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | 主引用文献 | Crystal Structure of the Lipoprotein_17 domain from Q9PRA0_UREPA protein of Ureaplasma parvum. To be Published
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3K2Y
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![BU of 3k2y by Molmil](/molmil-images/mine/3k2y) | Crystal structure of protein lp_0118 from Lactobacillus plantarum,northeast structural genomics consortium target LpR91B | 分子名称: | uncharacterized protein lp_0118 | 著者 | Seetharaman, J, Lew, S, Vorobiev, S.M, Wang, D, Janjua, H, Cunningham, K, Owens, L, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2009-09-30 | 公開日 | 2009-11-17 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal structure of protein lp_0118 from Lactobacillus plantarum,northeast structural genomics consortium target LpR91B To be Published
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7CAI
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![BU of 7cai by Molmil](/molmil-images/mine/7cai) | SARS-CoV-2 S trimer with two RBDs in the open state and complexed with two H014 Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of H014 Fab, ... | 著者 | Zhe, L, Cao, L, Deng, Y, Sun, Y, Wang, N, Xie, L, Wang, Y, Rao, Z, Qin, C, Wang, X. | 登録日 | 2020-06-08 | 公開日 | 2020-09-23 | 最終更新日 | 2020-09-30 | 実験手法 | ELECTRON MICROSCOPY (3.49 Å) | 主引用文献 | Structural basis for neutralization of SARS-CoV-2 and SARS-CoV by a potent therapeutic antibody. Science, 369, 2020
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3G9V
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![BU of 3g9v by Molmil](/molmil-images/mine/3g9v) | Crystal structure of a soluble decoy receptor IL-22BP bound to interleukin-22 | 分子名称: | Interleukin 22 receptor, alpha 2, Interleukin-22 | 著者 | de Moura, P.R, Watanabe, L, Bleicher, L, Colau, D, Renauld, J.-C, Polikarpov, I. | 登録日 | 2009-02-14 | 公開日 | 2009-04-14 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.756 Å) | 主引用文献 | Crystal structure of a soluble decoy receptor IL-22BP bound to interleukin-22 FEBS Lett., 583, 2009
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3K2Q
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![BU of 3k2q by Molmil](/molmil-images/mine/3k2q) | Crystal structure of Pyrophosphate-dependent phosphofructokinase from Marinobacter aquaeolei, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET MqR88 | 分子名称: | Pyrophosphate-dependent phosphofructokinase, SODIUM ION | 著者 | Seetharaman, J, Lew, S, Wang, D, Neely, H, Janjua, K, Cunningham, K, Owens, L, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2009-09-30 | 公開日 | 2009-11-17 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structure of Pyrophosphate-dependent phosphofructokinase from Marinobacter aquaeolei, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET MqR88 To be Published
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3K63
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![BU of 3k63 by Molmil](/molmil-images/mine/3k63) | X-ray structure of the PF04200 domain from Q9PRA0_UREPA protein of Ureaplasma parvum. NESG target UuR17a. | 分子名称: | Conserved hypothetical membrane lipoprotein | 著者 | Vorobiev, S, Neely, H, Seetharaman, J, Lee, D, Ciccosanti, C, Mao, L, Xiao, R, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2009-10-08 | 公開日 | 2009-10-20 | 最終更新日 | 2017-10-25 | 実験手法 | X-RAY DIFFRACTION (2.494 Å) | 主引用文献 | X-ray structure of the PF04200 domain from Q9PRA0_UREPA protein of Ureaplasma parvum. To be Published
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3JZE
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![BU of 3jze by Molmil](/molmil-images/mine/3jze) | 1.8 Angstrom resolution crystal structure of dihydroorotase (pyrC) from Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 | 分子名称: | ACETIC ACID, BETA-MERCAPTOETHANOL, CHLORIDE ION, ... | 著者 | Minasov, G, Halavaty, A, Shuvalova, L, Dubrovska, I, Winsor, J, Papazisi, L, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2009-09-23 | 公開日 | 2009-09-29 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | 1.8 Angstrom Resolution Crystal Structure of Dihydroorotase (pyrC) from Salmonella enterica subsp. enterica serovar Typhimurium str. LT2. TO BE PUBLISHED
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