5ZK1

Crystal Structure of the CRTC2(SeMet)-CREB-CRE complex

Summary for 5ZK1

• Entry DOI: 10.2210/pdb5zk1/pdb
• Descriptor: DNA (5'-D(*CP*TP*TP*GP*GP*CP*TP*GP*AP*CP*GP*TP*CP*AP*GP*CP*CP*AP*AP*G)-3'), Cyclic AMP-responsive element-binding protein 1, CREB-regulated transcription coactivator 2, ... (4 entities in total)
• Functional Keywords: transcription factor, co-activator, creb, cre, crtc, transcription-dna complex, transcription/dna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 18301.07

Authors

Xiang, S.,Zhai, L.,Valencia-Swain, J. (deposition date: 2018-03-22, release date: 2018-06-20, Last modification date: 2023-11-22)

• Primary citation: Song, Y.,Zhai, L.,Valencia Swain, J.,Chen, Y.,Wang, P.,Chen, L.,Liu, Y.,Xiang, S.; Structural Insights into the CRTC2-CREB Complex Assembly on CRE.; J. Mol. Biol., 430:1926-1939, 2018; PubMed: 29733854; DOI: 10.1016/j.jmb.2018.04.038

Experimental method

X-RAY DIFFRACTION (3.05 Å)