5ZK1

Crystal Structure of the CRTC2(SeMet)-CREB-CRE complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0003700	molecular_function	DNA-binding transcription factor activity
A	0005634	cellular_component	nucleus
A	0006355	biological_process	regulation of DNA-templated transcription
C	0005634	cellular_component	nucleus
C	0005737	cellular_component	cytoplasm
C	0008140	molecular_function	cAMP response element binding protein binding
C	0032793	biological_process	positive regulation of CREB transcription factor activity
C	0051289	biological_process	protein homotetramerization

Functional Information from PROSITE/UniProt

site_id	PS00036
Number of Residues	15
Details	BZIP_BASIC Basic-leucine zipper (bZIP) domain signature. Rlm.KNReAAREsRRK

Chain	Residue	Details
A	ARG289-LYS303

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	MOD_RES: Asymmetric dimethylarginine; by PRMT6 => ECO:0000269|PubMed:24570487

Chain	Residue	Details
C	ARG51

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site_id	SWS_FT_FI2
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1) => ECO:0000269|PubMed:12552083

Chain	Residue	Details
A	LEU290

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