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6EYV
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BU of 6eyv by Molmil
Crystal structure of the pyoverdine maturation protein PvdP in complex with the mock substrates L-tyrosine and zinc.
分子名称: PvdP, TYROSINE, ZINC ION
著者Poppe, J, Blankenfeldt, W.
登録日2017-11-13
公開日2018-08-01
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.704 Å)
主引用文献Pseudomonas aeruginosapyoverdine maturation enzyme PvdP has a noncanonical domain architecture and affords insight into a new subclass of tyrosinases.
J. Biol. Chem., 293, 2018
6ET0
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BU of 6et0 by Molmil
Crystal structure of PqsBC (C129A) mutant from Pseudomonas aeruginosa (crystal form 1)
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, ...
著者Witzgall, F, Blankenfeldt, W.
登録日2017-10-25
公開日2018-07-04
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献The Alkylquinolone Repertoire of Pseudomonas aeruginosa is Linked to Structural Flexibility of the FabH-like 2-Heptyl-3-hydroxy-4(1H)-quinolone (PQS) Biosynthesis Enzyme PqsBC.
Chembiochem, 19, 2018
6ESZ
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BU of 6esz by Molmil
Crystal structure of PqsBC from Pseudomonas aeruginosa (crystal form 1)
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, DI(HYDROXYETHYL)ETHER, PqsB, ...
著者Witzgall, F, Blankenfeldt, W.
登録日2017-10-25
公開日2018-07-04
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献The Alkylquinolone Repertoire of Pseudomonas aeruginosa is Linked to Structural Flexibility of the FabH-like 2-Heptyl-3-hydroxy-4(1H)-quinolone (PQS) Biosynthesis Enzyme PqsBC.
Chembiochem, 19, 2018
6EV2
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BU of 6ev2 by Molmil
Crystal structure of antibody against schizophyllan in complex with laminarihexaose
分子名称: Heavy chain, Light chain, beta-D-glucopyranose, ...
著者Sung, K.H, Josewski, J, Duebel, S, Blankenfeldt, W, Rau, U.
登録日2017-11-01
公開日2018-09-26
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.403 Å)
主引用文献Structural insights into antigen recognition of an anti-beta-(1,6)-beta-(1,3)-D-glucan antibody.
Sci Rep, 8, 2018
6ET3
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BU of 6et3 by Molmil
Crystal structure of PqsBC (C129S) mutant from Pseudomonas aeruginosa (crystal form 4)
分子名称: (R,R)-2,3-BUTANEDIOL, PqsB, PqsC, ...
著者Witzgall, F, Blankenfeldt, W.
登録日2017-10-25
公開日2018-07-04
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献The Alkylquinolone Repertoire of Pseudomonas aeruginosa is Linked to Structural Flexibility of the FabH-like 2-Heptyl-3-hydroxy-4(1H)-quinolone (PQS) Biosynthesis Enzyme PqsBC.
Chembiochem, 19, 2018
6FHP
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BU of 6fhp by Molmil
DAIP in complex with a C-terminal fragment of thermolysin
分子名称: Dispase autolysis-inducing protein, Thermolysin
著者Schmelz, S, Fiebig, D, Fuchsbauer, H.L, Blankenfeldt, W, Scrima, A.
登録日2018-01-15
公開日2018-09-12
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.703 Å)
主引用文献Destructive twisting of neutral metalloproteases: the catalysis mechanism of the Dispase autolysis-inducing protein from Streptomyces mobaraensis DSM 40487.
FEBS J., 285, 2018
6FNT
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BU of 6fnt by Molmil
Ergothioneine-biosynthetic methyltransferase EgtD in complex with pyrrolidinohistidine
分子名称: Histidine N-alpha-methyltransferase, Pyrrolidinohistidine
著者Vit, A, Blankenfeldt, W, Seebeck, F.P.
登録日2018-02-05
公開日2018-06-13
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Inhibition and Regulation of the Ergothioneine Biosynthetic Methyltransferase EgtD.
ACS Chem. Biol., 13, 2018
6FRH
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BU of 6frh by Molmil
Crystal structure of Ssp DnaB Mini-Intein variant M86
分子名称: Replicative DNA helicase,Replicative DNA helicase
著者Popp, M.A, Blankenfeldt, W, Gazdag, M.E, Matern, J.J.C, Mootz, H.D.
登録日2018-02-15
公開日2019-01-30
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献A functional interplay between intein and extein sequences in protein splicing compensates for the essential block B histidine.
Chem Sci, 10, 2019
6FNR
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BU of 6fnr by Molmil
Ergothioneine-biosynthetic methyltransferase EgtD in complex with chlorohistidine
分子名称: (2~{S})-2-chloranyl-3-(1~{H}-imidazol-5-yl)propanoic acid, GLYCEROL, Histidine N-alpha-methyltransferase, ...
著者Vit, A, Blankenfeldt, W, Seebeck, F.P.
登録日2018-02-05
公開日2018-06-13
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Inhibition and Regulation of the Ergothioneine Biosynthetic Methyltransferase EgtD.
ACS Chem. Biol., 13, 2018
6GKX
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BU of 6gkx by Molmil
Crystal structure of the R-type bacteriocin tube protein CD1364 from Clostridium difficile in the pre-assembled state
分子名称: Putative phage XkdM-like protein
著者Schwemmlein, N, Pippel, J, Gazdag, E.M, Blankenfeldt, W.
登録日2018-05-22
公開日2018-08-22
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal Structures of R-Type Bacteriocin Sheath and Tube Proteins CD1363 and CD1364 FromClostridium difficilein the Pre-assembled State.
Front Microbiol, 9, 2018
6GKW
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BU of 6gkw by Molmil
Crystal structure of the R-type bacteriocin sheath protein CD1363 from Clostridium difficile in the pre-assembled state
分子名称: Putative phage XkdK-like protein
著者Schwemmlein, N, Pippel, J, Gazdag, E.M, Blankenfeldt, W.
登録日2018-05-22
公開日2018-08-22
最終更新日2018-08-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structures of R-Type Bacteriocin Sheath and Tube Proteins CD1363 and CD1364 FromClostridium difficilein the Pre-assembled State.
Front Microbiol, 9, 2018
6FRG
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BU of 6frg by Molmil
Crystal structure of G-1F mutant of Ssp DnaB Mini-Intein variant M86
分子名称: DI(HYDROXYETHYL)ETHER, PENTAETHYLENE GLYCOL, Replicative DNA helicase, ...
著者Popp, M.A, Blankenfeldt, W, Friedel, K, Mootz, H.D.
登録日2018-02-15
公開日2019-01-30
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.535 Å)
主引用文献A functional interplay between intein and extein sequences in protein splicing compensates for the essential block B histidine.
Chem Sci, 10, 2019
6FNQ
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BU of 6fnq by Molmil
Ergothioneine-biosynthetic methyltransferase EgtD in complex with N,N,N-trimethylhistidine (hercynine)
分子名称: GLYCEROL, Histidine N-alpha-methyltransferase, MAGNESIUM ION, ...
著者Vit, A, Blankenfeldt, W, Seebeck, F.P.
登録日2018-02-05
公開日2018-06-13
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Inhibition and Regulation of the Ergothioneine Biosynthetic Methyltransferase EgtD.
ACS Chem. Biol., 13, 2018
6FRE
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BU of 6fre by Molmil
Crystal structure of G-1F/H73A mutant of Ssp DnaB Mini-Intein variant M86
分子名称: Replicative DNA helicase,Replicative DNA helicase
著者Popp, M.A, Blankenfeldt, W, Friedel, K, Mootz, H.D.
登録日2018-02-15
公開日2019-01-30
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.22 Å)
主引用文献A functional interplay between intein and extein sequences in protein splicing compensates for the essential block B histidine.
Chem Sci, 10, 2019
6FNS
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BU of 6fns by Molmil
Ergothioneine-biosynthetic methyltransferase EgtD in complex with morpholinohistidine
分子名称: GLYCEROL, Histidine N-alpha-methyltransferase, Morpholinohistidine
著者Vit, A, Blankenfeldt, W, Seebeck, F.P.
登録日2018-02-05
公開日2018-06-13
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Inhibition and Regulation of the Ergothioneine Biosynthetic Methyltransferase EgtD.
ACS Chem. Biol., 13, 2018
4ZYO
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BU of 4zyo by Molmil
Crystal Structure of Human Integral Membrane Stearoyl-CoA Desaturase with Substrate
分子名称: Acyl-CoA desaturase, DODECYL-BETA-D-MALTOSIDE, STEAROYL-COENZYME A, ...
著者Wang, H, Klein, M.G, Lane, W, Snell, G, Levin, I, Li, K, Zou, H, Sang, B.-C.
登録日2015-05-21
公開日2015-06-17
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Crystal structure of human stearoyl-coenzyme A desaturase in complex with substrate.
Nat.Struct.Mol.Biol., 22, 2015
4AY7
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BU of 4ay7 by Molmil
methyltransferase from Methanosarcina mazei
分子名称: MAGNESIUM ION, METHYLCOBALAMIN: COENZYME M METHYLTRANSFERASE, ZINC ION
著者Hoeppner, A, Thomas, F, Rueppel, A, Hensel, R, Blankenfeld, W, Bayer, P, Faust, A.
登録日2012-06-18
公開日2012-10-31
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of the Corrinoid:Coenzyme M Methyltransferase Mtaa from Methanosarcina Mazei
Acta Crystallogr.,Sect.D, 68, 2012
5HIO
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BU of 5hio by Molmil
Crystal Structure of PQS Response Protein PqsE in Complex with 2-aminobenzoylacetate
分子名称: 3-(2-aminophenyl)-3-oxopropanoic acid, FE (III) ION, PqsE
著者Witzgall, F, Blankenfeldt, W.
登録日2016-01-12
公開日2016-04-27
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Dissecting the Multiple Roles of PqsE in Pseudomonas aeruginosa Virulence by Discovery of Small Tool Compounds.
Acs Chem.Biol., 11, 2016
5HIP
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BU of 5hip by Molmil
Crystal Structure of PQS Response Protein PqsE in Complex with 2-(pyridin-3-yl)benzoic acid
分子名称: 2-(pyridin-3-yl)benzoic acid, FE (III) ION, PqsE
著者Witzgall, F, Blankenfeldt, W.
登録日2016-01-12
公開日2016-04-27
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.992 Å)
主引用文献Dissecting the Multiple Roles of PqsE in Pseudomonas aeruginosa Virulence by Discovery of Small Tool Compounds.
Acs Chem.Biol., 11, 2016
5HIQ
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BU of 5hiq by Molmil
Crystal Structure of PQS Response Protein PqsE in Complex with 2-(1H-pyrrol-1-yl)benzoic acid
分子名称: 2-pyrrol-1-ylbenzoic acid, FE (III) ION, PqsE
著者Witzgall, F, Blankenfeldt, W.
登録日2016-01-12
公開日2016-04-27
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Dissecting the Multiple Roles of PqsE in Pseudomonas aeruginosa Virulence by Discovery of Small Tool Compounds.
Acs Chem.Biol., 11, 2016
5HIS
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BU of 5his by Molmil
Crystal Structure of PQS Response Protein PqsE in Complex with 3-methylthiophene-2-carboxylic acid
分子名称: 3-methylthiophene-2-carboxylic acid, FE (III) ION, PqsE
著者Witzgall, F, Blankenfeldt, W.
登録日2016-01-12
公開日2016-04-27
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Dissecting the Multiple Roles of PqsE in Pseudomonas aeruginosa Virulence by Discovery of Small Tool Compounds.
Acs Chem.Biol., 11, 2016
4GTR
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BU of 4gtr by Molmil
FTase in complex with BMS analogue 13
分子名称: 4-({(3R)-7-cyano-4-[(4-methoxyphenyl)sulfonyl]-1-[(1-methyl-1H-imidazol-5-yl)methyl]-2,3,4,5-tetrahydro-1H-1,4-benzodiazepin-3-yl}methyl)phenyl diethylcarbamate, DIMETHYL SULFOXIDE, FARNESYL DIPHOSPHATE, ...
著者Guo, Z, Stigter, E.A, Bon, R.S, Waldmann, H, Blankenfeldt, W, Goody, R.S.
登録日2012-08-29
公開日2012-10-24
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Development of Selective, Potent RabGGTase Inhibitors
J.Med.Chem., 55, 2012
3PZ1
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BU of 3pz1 by Molmil
Crystal structure of RabGGTase(DELTA LRR; DELTA IG) in Complex with BMS3
分子名称: (3R)-3-benzyl-4-[(4-methoxyphenyl)sulfonyl]-1-[(1-methyl-1H-imidazol-5-yl)methyl]-2,3,4,5-tetrahydro-1H-1,4-benzodiazepine-7-carbonitrile, CALCIUM ION, DIMETHYL SULFOXIDE, ...
著者Guo, Z, Bon, R.S, Stigter, E.A, Waldmann, H, Alexandrov, K, Blankenfeldt, W, Goody, R.S.
登録日2010-12-14
公開日2011-05-11
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structure-Guided Development of Selective RabGGTase Inhibitors.
Angew.Chem.Int.Ed.Engl., 50, 2011
4HMS
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BU of 4hms by Molmil
Crystal structure of PhzG from Pseudomonas fluorescens 2-79 in complex with a second FMN in the substrate binding site
分子名称: FLAVIN MONONUCLEOTIDE, Phenazine biosynthesis protein phzG, SULFATE ION
著者Xu, N.N, Ahuja, E.G, Blankenfeldt, W.
登録日2012-10-18
公開日2013-08-07
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.33 Å)
主引用文献Trapped intermediates in crystals of the FMN-dependent oxidase PhzG provide insight into the final steps of phenazine biosynthesis
Acta Crystallogr.,Sect.D, 69, 2013
3QBT
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BU of 3qbt by Molmil
Crystal structure of OCRL1 540-678 in complex with Rab8a:GppNHp
分子名称: Inositol polyphosphate 5-phosphatase OCRL-1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
著者Hou, X, Hagemann, N, Schoebel, S, Blankenfeldt, W, Goody, R.S, Erdmann, K.S, Itzen, A.
登録日2011-01-14
公開日2011-03-23
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A structural basis for Lowe syndrome caused by mutations in the Rab-binding domain of OCRL1.
Embo J., 30, 2011

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