6BJR
 
 | | Crystal structure of prothrombin mutant S101C/A470C | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, Prothrombin, ... | | 著者 | Chinnaraj, M, Chen, Z, Pelc, L, Grese, Z, Bystranowska, D, Di Cera, E, Pozzi, N. | | 登録日 | 2017-11-06 | | 公開日 | 2018-06-27 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (6 Å) | | 主引用文献 | Structure of prothrombin in the closed form reveals new details on the mechanism of activation.
Sci Rep, 8, 2018
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6C2W
 | | Crystal structure of human prothrombin mutant S101C/A470C | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, Prothrombin, ... | | 著者 | Chinnaraj, M, Chen, Z, Pelc, L, Grese, Z, Bystranowska, D, Di Cera, E, Pozzi, N. | | 登録日 | 2018-01-09 | | 公開日 | 2018-02-28 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (4.12 Å) | | 主引用文献 | Structure of prothrombin in the closed form reveals new details on the mechanism of activation.
Sci Rep, 8, 2018
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2AYP
 | | Crystal Structure of CHK1 with an Indol Inhibitor | | 分子名称: | (3Z)-6-(4-HYDROXY-3-METHOXYPHENYL)-3-(1H-PYRROL-2-YLMETHYLENE)-1,3-DIHYDRO-2H-INDOL-2-ONE, Serine/threonine-protein kinase Chk1 | | 著者 | Lin, N.-H, Xia, P, Kovar, P, Chen, Z, Zhang, H, Rosenberg, S.H, Sham, H.L. | | 登録日 | 2005-09-07 | | 公開日 | 2006-09-12 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Synthesis and biological evaluation of 3-ethylidene-1,3-dihydro-indol-2-ones as novel checkpoint 1 inhibitors
Bioorg.Med.Chem.Lett., 16, 2006
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1T3Y
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1T3X
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8HB2
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8HAZ
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8HBB
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4RKJ
 | | Crystal structure of thrombin mutant S195T (free form) | | 分子名称: | GLYCEROL, POTASSIUM ION, Thrombin heavy chain, ... | | 著者 | Pelc, A.L, Chen, Z, Gohara, D.W, Vogt, A.D, Pozzi, N, Di Cera, E. | | 登録日 | 2014-10-13 | | 公開日 | 2015-03-11 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Why ser and not thr brokers catalysis in the trypsin fold.
Biochemistry, 54, 2015
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4RKO
 | | Crystal structure of thrombin mutant S195T bound with PPACK | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, ... | | 著者 | Pelc, A.L, Chen, Z, Gohara, D.W, Vogt, A.D, Pozzi, N, Di Cera, E. | | 登録日 | 2014-10-13 | | 公開日 | 2015-03-11 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | | 主引用文献 | Why ser and not thr brokers catalysis in the trypsin fold.
Biochemistry, 54, 2015
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5D0N
 | | Crystal structure of maize PDRP bound with AMP | | 分子名称: | ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, Pyruvate, ... | | 著者 | Jiang, L, Chen, Z. | | 登録日 | 2015-08-03 | | 公開日 | 2016-02-24 | | 最終更新日 | 2016-03-09 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural Basis of Reversible Phosphorylation by Maize Pyruvate Orthophosphate Dikinase Regulatory Protein
Plant Physiol., 170, 2016
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8XQ3
 | | Structure of Nipah virus Bangladesh string G protein ectodomain tetramer bound to single-domain antibody n425 at 5.87 Angstroms overall resolution | | 分子名称: | Nipah virus Bangladesh string G protein, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Sun, L, Chen, Z, Sun, Y, Mao, Q. | | 登録日 | 2024-01-04 | | 公開日 | 2024-09-18 | | 実験手法 | ELECTRON MICROSCOPY (5.87 Å) | | 主引用文献 | Fully human single-domain antibody targeting a highly conserved cryptic epitope on the Nipah virus G protein.
Nat Commun, 15, 2024
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8XPS
 | | Structure of Nipah virus Bangladesh string G protein ectodomain monomer bound to single-domain antibody n425 at 3.22 Angstroms overall resolution | | 分子名称: | Nipah virus Bangladesh string G protein, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Sun, L, Chen, Z, Sun, Y, Mao, Q. | | 登録日 | 2024-01-04 | | 公開日 | 2024-09-18 | | 実験手法 | ELECTRON MICROSCOPY (3.22 Å) | | 主引用文献 | Fully human single-domain antibody targeting a highly conserved cryptic epitope on the Nipah virus G protein.
Nat Commun, 15, 2024
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8XPY
 | | Structure of Nipah virus Malaysia string G protein ectodomain monomer bound to single-domain antibody n425 at 3.63 Angstroms overall resolution | | 分子名称: | Glycoprotein G, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Sun, L, Chen, Z, Sun, Y, Mao, Q. | | 登録日 | 2024-01-04 | | 公開日 | 2024-09-18 | | 実験手法 | ELECTRON MICROSCOPY (3.63 Å) | | 主引用文献 | Fully human single-domain antibody targeting a highly conserved cryptic epitope on the Nipah virus G protein.
Nat Commun, 15, 2024
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5D1F
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1Z71
 | | thrombin and P2 pyridine N-oxide inhibitor complex structure | | 分子名称: | Hirudin IIIB', L17, thrombin | | 著者 | Nantermet, P.G, Burgey, C.S, Robinson, K.A, Pellicore, J.M, Newton, C.L, Deng, J.Z, Lyle, T.A, Selnick, H.G, Lewis, S.D, Lucas, B.J, Krueger, J.A, Miller-Stein, C, White, R.B, Wong, B, McMasters, D.R, Wallace, A.A, Lynch Jr, J.J, Yan, Y, Chen, Z, Kuo, L, Gardell, S.J, Shafer, J.A, Vacca, J.P. | | 登録日 | 2005-03-23 | | 公開日 | 2005-05-17 | | 最終更新日 | 2017-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | P(2) pyridine N-oxide thrombin inhibitors: a novel peptidomimetic scaffold
BIOORG.MED.CHEM.LETT., 15, 2005
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5EYI
 | | Structure of PRRSV apo-NSP11 at 2.16A | | 分子名称: | 2-(2-METHOXYETHOXY)ETHANOL, CHLORIDE ION, Non-structural protein 11, ... | | 著者 | Zhang, M.F, Chen, Z. | | 登録日 | 2015-11-25 | | 公開日 | 2016-10-12 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | | 主引用文献 | Structural Biology of the Arterivirus nsp11 Endoribonucleases.
J. Virol., 91, 2017
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1IEH
 | | SOLUTION STRUCTURE OF A SOLUBLE SINGLE-DOMAIN ANTIBODY WITH HYDROPHOBIC RESIDUES TYPICAL OF A VL/VH INTERFACE | | 分子名称: | BRUC.D4.4 | | 著者 | Vranken, W, Tolkatchev, D, Xu, P, Tanha, J, Chen, Z, Narang, S, Ni, F. | | 登録日 | 2001-04-09 | | 公開日 | 2002-08-07 | | 最終更新日 | 2022-02-23 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of a llama single-domain antibody with hydrophobic residues typical of the VH/VL interface.
Biochemistry, 41, 2002
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3MMW
 | | Crystal structure of endoglucanase Cel5A from the hyperthermophilic Thermotoga maritima | | 分子名称: | CADMIUM ION, Endoglucanase | | 著者 | Pereira, J.H, Chen, Z, McAndrew, R.P, Sapra, R, Chhabra, S.R, Sale, K.L. | | 登録日 | 2010-04-20 | | 公開日 | 2010-07-28 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Biochemical characterization and crystal structure of endoglucanase Cel5A from the hyperthermophilic Thermotoga maritima.
J.Struct.Biol., 172, 2010
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2IAA
 | | Crystal Structure of an Electron Transfer Complex Between Aromatic Amine Dephydrogenase and Azurin from Alcaligenes Faecalis (Form 2) | | 分子名称: | Aromatic Amine Dehydrogenase, Azurin, COPPER (II) ION | | 著者 | Sukumar, N, Chen, Z, Leys, D, Scrutton, N.S, Ferrati, D, Merli, A, Rossi, G.L, Bellamy, H.D, Chistoserdov, A, Davidson, V.L, Mathews, F.S. | | 登録日 | 2006-09-07 | | 公開日 | 2006-11-21 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Crystal Structure of an Electron Transfer Complex between Aromatic Amine Dehydrogenase and Azurin from Alcaligenes faecalis.
Biochemistry, 45, 2006
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3MMU
 | | Crystal structure of endoglucanase Cel5A from the hyperthermophilic Thermotoga maritima | | 分子名称: | CADMIUM ION, Endoglucanase, NICKEL (II) ION | | 著者 | Pereira, J.H, Chen, Z, McAndrew, R.P, Sapra, R, Chhabra, S.R, Sale, K.L, Simmons, B.A, Adams, P.D. | | 登録日 | 2010-04-20 | | 公開日 | 2010-07-28 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.201 Å) | | 主引用文献 | Biochemical characterization and crystal structure of endoglucanase Cel5A from the hyperthermophilic Thermotoga maritima.
J.Struct.Biol., 172, 2010
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4FWJ
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8HM2
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8HM1
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8HM3
 | | Complex of PPIase-BfUbb | | 分子名称: | GLYCEROL, MAGNESIUM ION, Peptidylprolyl isomerase, ... | | 著者 | Xu, J.H, Chen, Z, Gao, X. | | 登録日 | 2022-12-02 | | 公開日 | 2023-11-29 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | | 主引用文献 | Bacteroides fragilis ubiquitin homologue drives intraspecies bacterial competition in the gut microbiome.
Nat Microbiol, 9, 2024
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