5EYI

Structure of PRRSV apo-NSP11 at 2.16A

Summary for 5EYI

• Entry DOI: 10.2210/pdb5eyi/pdb
• Descriptor: Non-structural protein 11, SULFATE ION, CHLORIDE ION, ... (5 entities in total)
• Functional Keywords: non-structural protein 11, nsp11, beta interferon antagonist, endoribonuclease, hydrolase
• Biological source: PRRSV 16244B (Porcine reproductive and respiratory syndrome virus 16244B)
• Cellular location: Nsp1: Host nucleus . Nsp1-alpha papain-like cysteine proteinase: Host nucleus . Nsp1-beta papain-like cysteine proteinase: Host cytoplasm . Nsp2 cysteine proteinase: Host membrane ; Multi-pass membrane protein . Non-structural protein 3: Host membrane ; Multi-pass membrane protein . Non-structural protein 5-6-7: Host membrane ; Multi-pass membrane protein . 3C-like serine proteinase: Host cytoplasm . RNA-directed RNA polymerase: Host cytoplasm, host perinuclear region . Helicase: Host cytoplasm, host perinuclear region : Q9YN02
• Total number of polymer chains: 2
• Total formula weight: 50177.07

Authors

Zhang, M.F.,Chen, Z. (deposition date: 2015-11-25, release date: 2016-10-12, Last modification date: 2024-03-20)

• Primary citation: Zhang, M.,Li, X.,Deng, Z.,Chen, Z.,Liu, Y.,Gao, Y.,Wu, W.,Chen, Z.; Structural Biology of the Arterivirus nsp11 Endoribonucleases.; J. Virol., 91:-, 2017; PubMed: 27795409; DOI: 10.1128/JVI.01309-16

Experimental method

X-RAY DIFFRACTION (2.16 Å)