6WYV
| E. coli 50S ribosome bound to compounds 47 and VS1 | 分子名称: | (3R,4R,5E,10E,12E,14S,16R,26aR)-16-fluoro-14-hydroxy-12-methyl-3-(propan-2-yl)-4-(prop-2-en-1-yl)-3,4,8,9,14,15,16,17,24,25,26,26a-dodecahydro-1H,7H,22H-21,18-(azeno)pyrrolo[2,1-c][1,8,4,19]dioxadiazacyclotetracosine-1,7,22-trione, 23S ribosomal RNA, 50S ribosomal protein L13, ... | 著者 | Pellegrino, J, Lee, D.J, Fraser, J.S, Seiple, I.B. | 登録日 | 2020-05-13 | 公開日 | 2020-06-17 | 最終更新日 | 2020-10-07 | 実験手法 | ELECTRON MICROSCOPY (2.75 Å) | 主引用文献 | Synthetic group A streptogramin antibiotics that overcome Vat resistance. Nature, 586, 2020
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6X3C
| Crystal structure of streptogramin A acetyltransferase VatA from Staphylococcus aureus in complex with streptogramin analog F1037 (47) | 分子名称: | (3R,4R,5E,10E,12E,14S,16R,26aR)-16-fluoro-14-hydroxy-12-methyl-3-(propan-2-yl)-4-(prop-2-en-1-yl)-3,4,8,9,14,15,16,17,24,25,26,26a-dodecahydro-1H,7H,22H-21,18-(azeno)pyrrolo[2,1-c][1,8,4,19]dioxadiazacyclotetracosine-1,7,22-trione, CHLORIDE ION, MAGNESIUM ION, ... | 著者 | Chaires, H.A, Fraser, J.S. | 登録日 | 2020-05-21 | 公開日 | 2020-11-18 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | 主引用文献 | Synthetic group A streptogramin antibiotics that overcome Vat resistance. Nature, 586, 2020
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6X3J
| Crystal structure of streptogramin A acetyltransferase VatA from Staphylococcus aureus in complex with streptogramin analog F0224 (46) | 分子名称: | (2R)-2-[(3S,4R,5E,10E,12E,14S,16R,26aR)-16-fluoro-14-hydroxy-4,12-dimethyl-1,7,22-trioxo-4,7,8,9,14,15,16,17,24,25,26,26a-dodecahydro-1H,3H,22H-21,18-(azeno)pyrrolo[2,1-c][1,8,4,19]dioxadiazacyclotetracosin-3-yl]propyl isoquinolin-3-ylcarbamate, CHLORIDE ION, MAGNESIUM ION, ... | 著者 | Chaires, H.A, Fraser, J.S. | 登録日 | 2020-05-21 | 公開日 | 2020-11-18 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Synthetic group A streptogramin antibiotics that overcome Vat resistance. Nature, 586, 2020
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6BJX
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6JQH
| Crystal structure of MaDA | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, MaDA | 著者 | Du, X.X, Lei, X.G. | 登録日 | 2019-03-31 | 公開日 | 2020-04-08 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.303 Å) | 主引用文献 | FAD-dependent enzyme-catalysed intermolecular [4+2] cycloaddition in natural product biosynthesis. Nat.Chem., 12, 2020
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4HK6
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4HOW
| The crystal structure of isomaltulose synthase from Erwinia rhapontici NX5 | 分子名称: | CALCIUM ION, GLYCEROL, Sucrose isomerase | 著者 | Xu, Z, Li, S, Xu, H, Zhou, J. | 登録日 | 2012-10-22 | 公開日 | 2013-10-16 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The Structural Basis of Erwinia rhapontici Isomaltulose Synthase Plos One, 8, 2013
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4HPH
| The crystal structure of isomaltulose synthase mutant E295Q from Erwinia rhapontici NX5 in complex with its natural substrate sucrose | 分子名称: | CALCIUM ION, GLYCEROL, Sucrose isomerase, ... | 著者 | Xu, Z, Li, S, Xu, H, Zhou, J. | 登録日 | 2012-10-23 | 公開日 | 2013-10-16 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The Structural Basis of Erwinia rhapontici Isomaltulose Synthase Plos One, 8, 2013
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4HK7
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4HK5
| Crystal structure of Cordyceps militaris IDCase in apo form | 分子名称: | Uracil-5-carboxylate decarboxylase, ZINC ION | 著者 | Xu, S, Zhu, J, Ding, J. | 登録日 | 2012-10-15 | 公開日 | 2013-09-11 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase. Cell Res., 23, 2013
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4HOZ
| The crystal structure of isomaltulose synthase mutant D241A from Erwinia rhapontici NX5 in complex with D-glucose | 分子名称: | CALCIUM ION, GLYCEROL, Sucrose isomerase, ... | 著者 | Xu, Z, Li, S, Xu, H, Zhou, J. | 登録日 | 2012-10-23 | 公開日 | 2013-10-16 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The Structural Basis of Erwinia rhapontici Isomaltulose Synthase Plos One, 8, 2013
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4HJW
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4HXX
| Pyridinylpyrimidines selectively inhibit human methionine aminopeptidase-1 | 分子名称: | (1R)-N~2~-[5-chloro-2-(5-chloropyridin-2-yl)-6-methylpyrimidin-4-yl]-1-phenyl-N~1~-(4-phenylbutyl)ethane-1,2-diamine, COBALT (II) ION, Methionine aminopeptidase 1, ... | 著者 | Gabelli, S.B, Zhang, F, Liu, J, Amzel, L.M. | 登録日 | 2012-11-12 | 公開日 | 2013-04-03 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Pyridinylpyrimidines selectively inhibit human methionine aminopeptidase-1. Bioorg.Med.Chem., 21, 2013
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6D8M
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6D8O
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6D8L
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6D8N
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7FAE
| S protein of SARS-CoV-2 in complex bound with P36-5D2(state2) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, P36-5D2 heavy chain, ... | 著者 | Zhang, L, Wang, X, Shan, S, Zhang, S. | 登録日 | 2021-07-06 | 公開日 | 2021-12-22 | 最終更新日 | 2022-02-16 | 実験手法 | ELECTRON MICROSCOPY (3.65 Å) | 主引用文献 | A Potent and Protective Human Neutralizing Antibody Against SARS-CoV-2 Variants. Front Immunol, 12, 2021
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7FAF
| S protein of SARS-CoV-2 in complex bound with P36-5D2 (state1) | 分子名称: | P36-5D2 heavy chain, P36-5D2 light chain, Spike glycoprotein | 著者 | Zhang, L, Wang, X, Zhang, S, Shan, S. | 登録日 | 2021-07-06 | 公開日 | 2021-12-22 | 最終更新日 | 2022-02-16 | 実験手法 | ELECTRON MICROSCOPY (3.69 Å) | 主引用文献 | A Potent and Protective Human Neutralizing Antibody Against SARS-CoV-2 Variants. Front Immunol, 12, 2021
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7XRE
| Crystal structure of DgpA | 分子名称: | DgpA, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | 著者 | Ma, W, He, P. | 登録日 | 2022-05-10 | 公開日 | 2023-02-15 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.76 Å) | 主引用文献 | Structural mechanism of a dual-functional enzyme DgpA/B/C as both a C -glycoside cleaving enzyme and an O - to C -glycoside isomerase. Acta Pharm Sin B, 13, 2023
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7XRF
| Crystal structaure of DgpB/C complex | 分子名称: | AP_endonuc_2 domain-containing protein, DgpB, MANGANESE (II) ION | 著者 | Ma, M, He, P. | 登録日 | 2022-05-10 | 公開日 | 2023-02-15 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.137 Å) | 主引用文献 | Structural mechanism of a dual-functional enzyme DgpA/B/C as both a C -glycoside cleaving enzyme and an O - to C -glycoside isomerase. Acta Pharm Sin B, 13, 2023
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7XR9
| Crystal structure of DgpA with glucose | 分子名称: | DgpA, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, beta-D-glucopyranose | 著者 | Ma, W, He, P. | 登録日 | 2022-05-09 | 公開日 | 2023-04-05 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.42 Å) | 主引用文献 | Structural mechanism of a dual-functional enzyme DgpA/B/C as both a C -glycoside cleaving enzyme and an O - to C -glycoside isomerase. Acta Pharm Sin B, 13, 2023
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3GXL
| ALK-5 kinase complex with GW857175 | 分子名称: | N-1H-indazol-5-yl-2-(6-methylpyridin-2-yl)quinazolin-4-amine, TGF-beta receptor type-1 | 著者 | Smith, W, Janson, C. | 登録日 | 2009-04-02 | 公開日 | 2009-04-21 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Design of novel quinazoline derivatives and related analogues as potent and selective ALK5 inhibitors Bioorg.Med.Chem.Lett., 19, 2009
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8GT9
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8GU7
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