5GUH
 
 | | Crystal structure of silkworm PIWI-clade Argonaute Siwi bound to piRNA | | 分子名称: | MAGNESIUM ION, PIWI, RNA (28-MER) | | 著者 | Matsumoto, N, Nishimasu, H, Ishitani, R, Nureki, O. | | 登録日 | 2016-08-29 | | 公開日 | 2016-10-19 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal Structure of Silkworm PIWI-Clade Argonaute Siwi Bound to piRNA
Cell, 167, 2016
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1GEB
 | | X-RAY CRYSTAL STRUCTURE AND CATALYTIC PROPERTIES OF THR252ILE MUTANT OF CYTOCHROME P450CAM | | 分子名称: | CAMPHOR, CYTOCHROME P450-CAM, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Hishiki, T, Shimada, H, Nagano, S, Park, S.-Y, Ishimura, Y. | | 登録日 | 2000-11-01 | | 公開日 | 2000-11-15 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | | 主引用文献 | X-ray crystal structure and catalytic properties of Thr252Ile mutant of cytochrome P450cam: roles of Thr252 and water in the active center.
J.Biochem., 128, 2000
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3PTR
 | | PHF2 Jumonji domain | | 分子名称: | 1,2-ETHANEDIOL, PHD finger protein 2 | | 著者 | Horton, J.R, Upadhyay, A.K, Hashimoto, H, Zhang, X, Cheng, X. | | 登録日 | 2010-12-03 | | 公開日 | 2011-01-26 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.954 Å) | | 主引用文献 | Structural basis for human PHF2 Jumonji domain interaction with metal ions.
J.Mol.Biol., 406, 2011
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3PUA
 | | PHF2 Jumonji-NOG-Ni(II) | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, N-OXALYLGLYCINE, ... | | 著者 | Horton, J.R, Upadhyay, A.K, Hashimoto, H, Zhang, X, Cheng, X. | | 登録日 | 2010-12-03 | | 公開日 | 2011-01-26 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | | 主引用文献 | Structural basis for human PHF2 Jumonji domain interaction with metal ions.
J.Mol.Biol., 406, 2011
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3PU3
 | | PHF2 Jumonji domain-NOG complex | | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, N-OXALYLGLYCINE, ... | | 著者 | Horton, J.R, Upadhyay, A.K, Hashimoto, H, Zhang, X, Cheng, X. | | 登録日 | 2010-12-03 | | 公開日 | 2011-01-26 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structural basis for human PHF2 Jumonji domain interaction with metal ions.
J.Mol.Biol., 406, 2011
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1IWI
 | | Putidaredoxin-Binding Stablilizes an Active Conformer of Cytochrome P450cam in its Reduced State; Crystal Structure of Cytochrome P450cam | | 分子名称: | CAMPHOR, CYTOCHROME P450-CAM, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Nagano, S, Shimada, H, Tarumi, A, Hishiki, T, Kimata-Ariga, Y, Egawa, T, Park, S.-Y, Adachi, S, Shiro, Y, Ishimura, Y, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2002-05-15 | | 公開日 | 2002-06-05 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Infrared spectroscopic and mutational studies on putidaredoxin-induced conformational changes in ferrous CO-P450cam
Biochemistry, 42, 2003
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8YHR
 | | DHODH in complex with furocoumavirin | | 分子名称: | 4-methyl-8-[(S)-oxidanyl(phenyl)methyl]-9-phenyl-furo[2,3-h]chromen-2-one, ACETATE ION, Dihydroorotate dehydrogenase (quinone), ... | | 著者 | Hara, K, Okumura, H, Nakahara, M, Sato, M, Hashimoto, H, Osada, H, Watanabe, K. | | 登録日 | 2024-02-28 | | 公開日 | 2024-05-22 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural and Functional Analyses of Inhibition of Human Dihydroorotate Dehydrogenase by Antiviral Furocoumavirin.
Biochemistry, 63, 2024
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6KBC
 | | Crystal structure of CghA with Sch210972 | | 分子名称: | (2S)-3-[(2S,4E)-4-[[(1R,2S,4aR,6S,8R,8aS)-2-[(E)-but-2-en-2-yl]-6,8-dimethyl-1,2,4a,5,6,7,8,8a-octahydronaphthalen-1-yl]-oxidanyl-methylidene]-3,5-bis(oxidanylidene)pyrrolidin-2-yl]-2-methyl-2-oxidanyl-propanoic acid, CghA | | 著者 | Hara, K, Hashimoto, H, Maeda, N, Sato, M, Watanabe, K. | | 登録日 | 2019-06-24 | | 公開日 | 2020-06-24 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | Catalytic mechanism and endo-to-exo selectivity reversion of an octalin-forming natural Diels-Alderase
Nat Catal, 2021
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6KJG
 | | Crystal structure of PsoF | | 分子名称: | Dual-functional monooxygenase/methyltransferase psoF | | 著者 | Hara, K, Hashimoto, H, Matsushita, T, Tsunematsu, Y, Watanabe, K. | | 登録日 | 2019-07-22 | | 公開日 | 2019-09-18 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | Functional and Structural Analyses oftrans C-Methyltransferase in Fungal Polyketide Biosynthesis.
Biochemistry, 58, 2019
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6KJI
 | | Crystal structure of PsoF with SAH | | 分子名称: | Dual-functional monooxygenase/methyltransferase psoF, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION | | 著者 | Hara, K, Hashimoto, H, Matsushita, T, Tsunematsu, Y, Watanabe, K. | | 登録日 | 2019-07-22 | | 公開日 | 2019-09-18 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | Functional and Structural Analyses oftrans C-Methyltransferase in Fungal Polyketide Biosynthesis.
Biochemistry, 58, 2019
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6L96
 | | Structure of PPARalpha-LBD/pemafibrate/SRC1 peptide | | 分子名称: | (2~{R})-2-[3-[[1,3-benzoxazol-2-yl-[3-(4-methoxyphenoxy)propyl]amino]methyl]phenoxy]butanoic acid, Peroxisome proliferator-activated receptor alpha, SRC1 coactivator peptide | | 著者 | Kawasaki, M, Kambe, A, Yamamoto, Y, Arulmozhira, S, Ito, S, Nakagawa, Y, Tokiwa, H, Nakano, S, Shimano, H. | | 登録日 | 2019-11-08 | | 公開日 | 2020-01-15 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Elucidation of Molecular Mechanism of a Selective PPAR alpha Modulator, Pemafibrate, through Combinational Approaches of X-ray Crystallography, Thermodynamic Analysis, and First-Principle Calculations.
Int J Mol Sci, 21, 2020
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2E8S
 | | Structural study of Project ID PH0725 from Pyrococcus horikoshii OT3 | | 分子名称: | Probable diphthine synthase, S-ADENOSYL-L-HOMOCYSTEINE, SODIUM ION | | 著者 | Asada, Y, Shimada, H, Taketa, M, Nakamoto, T, Kunishima, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2007-01-23 | | 公開日 | 2007-07-24 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural study of Project ID PH0725 from Pyrococcus horikoshii OT3
To be Published
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2EK4
 | | Structural study of Project ID PH0725 from Pyrococcus horikoshii OT3 (L8M) | | 分子名称: | S-ADENOSYL-L-HOMOCYSTEINE, SODIUM ION, diphthine synthase | | 著者 | Asada, Y, Shimada, H, Taketa, M, Matsuura, Y, Kunishima, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2007-03-22 | | 公開日 | 2007-09-25 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural study of Project ID PH0725 from Pyrococcus horikoshii OT3 (L8M)
To be Published
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2EK3
 | | Structural study of Project ID PH0725 from Pyrococcus horikoshii OT3 (L3M) | | 分子名称: | S-ADENOSYL-L-HOMOCYSTEINE, SODIUM ION, diphthine synthase | | 著者 | Asada, Y, Shimada, H, Taketa, M, Matsuura, Y, Kunishima, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2007-03-22 | | 公開日 | 2007-09-25 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural study of Project ID PH0725 from Pyrococcus horikoshii OT3 (L3M)
To be Published
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2EL3
 | | Structural study of Project ID PH0725 from Pyrococcus horikoshii OT3 (L242M) | | 分子名称: | S-ADENOSYL-L-HOMOCYSTEINE, SODIUM ION, diphthine synthase | | 著者 | Asada, Y, Matsuura, Y, Ono, N, Shimada, H, Kunishima, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2007-03-26 | | 公開日 | 2007-10-02 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural study of Project ID PH0725 from Pyrococcus horikoshii OT3 (L242M)
To be Published
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4QVZ
 | | FMRP N-terminal domain | | 分子名称: | 1,2-ETHANEDIOL, Fragile X mental retardation protein 1 | | 著者 | Myrick, L.K, Hashimoto, H, Cheng, X, Warren, S.T. | | 登録日 | 2014-07-16 | | 公開日 | 2014-12-03 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.195 Å) | | 主引用文献 | Human FMRP contains an integral tandem Agenet (Tudor) and KH motif in the amino terminal domain.
Hum.Mol.Genet., 24, 2015
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2E8R
 | | Structural study of Project ID PH0725 from Pyrococcus horikoshii OT3 | | 分子名称: | Probable diphthine synthase, S-ADENOSYL-L-HOMOCYSTEINE, SODIUM ION | | 著者 | Asada, Y, Taketa, M, Shimada, H, Matsuura, Y, Kunishima, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2007-01-23 | | 公開日 | 2007-07-24 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural study of Project ID PH0725 from Pyrococcus horikoshii OT3
To be Published
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4QW2
 | | FMRP N-terminal domain (R138Q) | | 分子名称: | 1,2-ETHANEDIOL, Fragile X mental retardation protein 1, LEAD (II) ION | | 著者 | Myrick, L.K, Hashimoto, H, Cheng, X, Warren, S.T. | | 登録日 | 2014-07-16 | | 公開日 | 2014-12-03 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.989 Å) | | 主引用文献 | Human FMRP contains an integral tandem Agenet (Tudor) and KH motif in the amino terminal domain.
Hum.Mol.Genet., 24, 2015
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2E8Q
 | | Structural study of Project ID PH0725 from Pyrococcus horikoshii OT3 (K19M) | | 分子名称: | Probable diphthine synthase, S-ADENOSYL-L-HOMOCYSTEINE | | 著者 | Asada, Y, Shimada, H, Taketa, M, Nakamoto, T, Kunishima, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2007-01-23 | | 公開日 | 2007-07-24 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural study of Project ID PH0725 from Pyrococcus horikoshii OT3 (K19M)
To be Published
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2EL0
 | | Structural study of Project ID PH0725 from Pyrococcus horikoshii OT3 (L21M) | | 分子名称: | S-ADENOSYL-L-HOMOCYSTEINE, diphthine synthase | | 著者 | Asada, Y, Matsuura, Y, Ono, N, Shimada, H, Kunishima, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2007-03-26 | | 公開日 | 2007-10-02 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural study of Project ID PH0725 from Pyrococcus horikoshii OT3 (L21M)
To be Published
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4P1O
 | | Crystal structure of the Bateman domain of murine magnesium transporter CNNM2 bound to ATP-Mg | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Metal transporter CNNM2 | | 著者 | Corral-Rodriguez, M.A, Stuiver, M, Abascal-Palacios, G, Diercks, T, Oyenarte, I, Ereno-Orbea, J, Encinar, J.A, Spiwok, V, Terashima, H, Accardi, A, Muller, D, Martinez-Cruz, L.A. | | 登録日 | 2014-02-27 | | 公開日 | 2015-04-15 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (3.06 Å) | | 主引用文献 | Structural and ligand binding properties of the Bateman domain of human magnesium transporters CNNM2 and CNNM4
To Be Published
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4P1G
 | | Crystal structure of the Bateman domain of murine magnesium transporter CNNM2 bound to AMP | | 分子名称: | ADENOSINE MONOPHOSPHATE, Metal transporter CNNM2 | | 著者 | Corral-Rodriguez, M.A, Stuiver, M, Abascal-Palacios, G, Diercks, T, Oyenarte, I, Ereno-Orbea, J, Encinar, J.A, Spiwok, V, Terashima, H, Accardi, A, Muller, D, Martinez-Cruz, L.A. | | 登録日 | 2014-02-26 | | 公開日 | 2015-03-04 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.603 Å) | | 主引用文献 | Structural and ligand binding properties of the Bateman domain of human magnesium transporters CNNM2 and CNNM4
To Be Published
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1J1R
 | | Structure of Pokeweed Antiviral Protein from Seeds (PAP-S1) Complexed with Adenine | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENINE, Antiviral Protein S | | 著者 | Watanabe, K, Sato, E, Honjo, E, Motoshima, H, Kurokawa, H, Mikami, B, Monzingo, A.F, Robertus, J.D, Fujii, H, Hidaka, A. | | 登録日 | 2002-12-14 | | 公開日 | 2004-02-03 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal Structure of Pokweed Antiviral Protein from Seeds (PAP-S1) at 1.8 Angstrom Resolution
To be published
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1J1S
 | | Pokeweed Antiviral Protein from Seeds (PAP-S1) Complexed with Formycin | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Antiviral Protein S, FORMYCIN-5'-MONOPHOSPHATE | | 著者 | Watanabe, K, Sato, E, Honjo, E, Motoshima, H, Kurokawa, H, Mikami, B, Monzingo, A.F, Robertus, J.D, Fujii, H, Hidaka, A. | | 登録日 | 2002-12-14 | | 公開日 | 2004-02-03 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal Structure of Pokweed Antiviral Protein from Seeds (PAP-S1) at 1.8 Angstrom Resolution
To be published
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6KR6
 | | Crystal structure of Drosophila Piwi | | 分子名称: | MERCURY (II) ION, Protein piwi, ZINC ION, ... | | 著者 | Yamaguchi, S, Oe, A, Yamashita, K, Hirano, S, Mastumoto, N, Ishitani, R, Nishimasu, H, Nureki, O. | | 登録日 | 2019-08-21 | | 公開日 | 2020-02-19 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Crystal structure of Drosophila Piwi.
Nat Commun, 11, 2020
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