5FFL
 
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4WYS
 | | Crystal structure of thiolase from Escherichia coli | | 分子名称: | Acetyl-CoA acetyltransferase | | 著者 | Kim, S, Ha, S.C, Ahn, J.W, Kim, E.J, Lim, J.H, Kim, K.J. | | 登録日 | 2014-11-18 | | 公開日 | 2015-10-07 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Redox-switch regulatory mechanism of thiolase from Clostridium acetobutylicum
Nat Commun, 6, 2015
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4WYR
 | | Crystal structure of thiolase mutation (V77Q,N153Y,A286K) from Clostridium acetobutylicum | | 分子名称: | Acetyl-CoA acetyltransferase, DI(HYDROXYETHYL)ETHER, GLYCEROL | | 著者 | Kim, S, Ha, S.C, Ahn, J.W, Kim, E.J, Lim, J.H, Kim, K.J. | | 登録日 | 2014-11-18 | | 公開日 | 2015-10-07 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Redox-switch regulatory mechanism of thiolase from Clostridium acetobutylicum
Nat Commun, 6, 2015
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4XL4
 | | Crystal structure of thiolase from Clostridium acetobutylicum in complex with CoA | | 分子名称: | Acetyl-CoA acetyltransferase, COENZYME A, GLYCEROL | | 著者 | Kim, S, Ha, S.C, Ahn, J.W, Kim, E.J, Lim, J.H, Kim, K.J. | | 登録日 | 2015-01-13 | | 公開日 | 2015-10-07 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Redox-switch regulatory mechanism of thiolase from Clostridium acetobutylicum
Nat Commun, 6, 2015
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6WKN
 | | PL-bound rat TRPV2 in nanodiscs | | 分子名称: | Transient receptor potential cation channel subfamily V member 2, piperlongumine | | 著者 | Pumroy, R.P, Moiseenkova-Bell, V.Y. | | 登録日 | 2020-04-16 | | 公開日 | 2021-04-21 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.46 Å) | | 主引用文献 | Allosteric Antagonist Modulation of TRPV2 by Piperlongumine Impairs Glioblastoma Progression.
Acs Cent.Sci., 7, 2021
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2QV2
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8HTG
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8HTI
 | | Human Consensus Olfactory Receptor OR52c in Complex with Octanoic Acid (OCA) and G Protein | | 分子名称: | Consensus Olfactory Receptor OR52c, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Choi, C.W, Bae, J, Choi, H.-J, Kim, J. | | 登録日 | 2022-12-21 | | 公開日 | 2023-12-20 | | 実験手法 | ELECTRON MICROSCOPY (2.97 Å) | | 主引用文献 | Understanding the molecular mechanisms of odorant binding and activation of the human OR52 family.
Nat Commun, 14, 2023
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7S5B
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7OPB
 | | IL7R in complex with an antagonist | | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, IL7R binder, ... | | 著者 | Markovic, I, Verschueren, K.H.G, Verstraete, K, Savvides, S.N. | | 登録日 | 2021-05-31 | | 公開日 | 2022-05-11 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.144 Å) | | 主引用文献 | Design of protein-binding proteins from the target structure alone.
Nature, 605, 2022
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5FS0
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7YUM
 | | MtaLon-Apo for the spiral oligomers of tetramer | | 分子名称: | Lon protease | | 著者 | Li, S, Hsieh, K, Kuo, C, Lee, S, Ho, M, Wang, C, Zhang, K, Chang, C.I. | | 登録日 | 2022-08-17 | | 公開日 | 2023-10-25 | | 最終更新日 | 2024-04-03 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine.
Nat Commun, 14, 2023
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7YUW
 | | MtaLon-ADP for the spiral oligomers of pentamer | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Lon protease | | 著者 | Li, S, Hsieh, K, Kuo, C, Lee, S, Ho, M, Wang, C, Zhang, K, Chang, C.I. | | 登録日 | 2022-08-18 | | 公開日 | 2023-10-25 | | 最終更新日 | 2024-04-03 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine.
Nat Commun, 14, 2023
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7YUT
 | | MtaLon-Apo for the spiral oligomers of hexamer | | 分子名称: | Lon protease | | 著者 | Li, S, Hsieh, K, Kuo, C, Lee, S, Ho, M, Wang, C, Zhang, K, Chang, C.I. | | 登録日 | 2022-08-17 | | 公開日 | 2023-10-25 | | 最終更新日 | 2024-04-03 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine.
Nat Commun, 14, 2023
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7YUV
 | | MtaLon-ADP for the spiral oligomers of tetramer | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Lon protease | | 著者 | Li, S, Hsieh, K, Kuo, C, Lee, S, Ho, M, Wang, C, Zhang, K, Chang, C.I. | | 登録日 | 2022-08-17 | | 公開日 | 2023-10-25 | | 最終更新日 | 2024-04-03 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine.
Nat Commun, 14, 2023
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7YUH
 | | MtaLon-Apo for the spiral oligomers of trimer | | 分子名称: | Lon protease | | 著者 | Li, S, Hsieh, K, Kuo, C, Lee, S, Ho, M, Wang, C, Zhang, K, Chang, C.I. | | 登録日 | 2022-08-17 | | 公開日 | 2023-10-25 | | 最終更新日 | 2024-04-03 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine.
Nat Commun, 14, 2023
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7YUP
 | | MtaLon-Apo for the spiral oligomers of pentamer | | 分子名称: | Lon protease | | 著者 | Li, S, Hsieh, K, Kuo, C, Lee, S, Ho, M, Wang, C, Zhang, K, Chang, C.I. | | 登録日 | 2022-08-17 | | 公開日 | 2023-10-25 | | 最終更新日 | 2024-04-03 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine.
Nat Commun, 14, 2023
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7YUX
 | | MtaLon-ADP for the spiral oligomers of hexamer | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Lon protease | | 著者 | Li, S, Hsieh, K, Kuo, C, Lee, S, Ho, M, Wang, C, Zhang, K, Chang, C.I. | | 登録日 | 2022-08-18 | | 公開日 | 2023-10-25 | | 最終更新日 | 2024-04-03 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine.
Nat Commun, 14, 2023
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7YUU
 | | MtaLon-ADP for the spiral oligomers of trimer | | 分子名称: | Lon protease | | 著者 | Li, S, Hsieh, K, Kuo, C, Lee, S, Ho, M, Wang, C, Zhang, K, Chang, C.I. | | 登録日 | 2022-08-17 | | 公開日 | 2023-10-25 | | 最終更新日 | 2024-04-03 | | 実験手法 | ELECTRON MICROSCOPY (5.8 Å) | | 主引用文献 | A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine.
Nat Commun, 14, 2023
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4W5J
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7C11
 | | Formate--tetrahydrofolate ligase from Methylobacterium extorquens CM4 strain | | 分子名称: | ACETATE ION, CITRATE ANION, Formate-tetrahydrofolate ligase, ... | | 著者 | Kim, K.-J, Kim, S, Seo, H, Lee, S. | | 登録日 | 2020-05-02 | | 公開日 | 2020-10-28 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.815 Å) | | 主引用文献 | Biochemical properties and crystal structure of formate-tetrahydrofolate ligase from Methylobacterium extorquens CM4.
Biochem.Biophys.Res.Commun., 528, 2020
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5HWT
 | | Crystal structure of apo-PAS1 | | 分子名称: | Sensor histidine kinase TodS | | 著者 | Hwang, J, Koh, S. | | 登録日 | 2016-01-29 | | 公開日 | 2016-03-02 | | 最終更新日 | 2017-12-06 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Molecular Insights into Toluene Sensing in the TodS/TodT Signal Transduction System.
J. Biol. Chem., 291, 2016
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5HWW
 | | Crystal structure of PAS1 complexed with 1,2,4-TMB | | 分子名称: | 1,2,4-trimethylbenzene, Sensor histidine kinase TodS | | 著者 | Hwang, J, Koh, S. | | 登録日 | 2016-01-29 | | 公開日 | 2016-03-02 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Molecular Insights into Toluene Sensing in the TodS/TodT Signal Transduction System.
J. Biol. Chem., 291, 2016
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5HWV
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6S41
 | | CRYSTAL STRUCTURE OF PXR IN COMPLEX WITH XPC-7455 | | 分子名称: | 4-[[(1~{S})-1-[2,5-bis(fluoranyl)phenyl]ethyl]amino]-5-chloranyl-2-fluoranyl-~{N}-(1,3-thiazol-4-yl)benzenesulfonamide, Nuclear receptor subfamily 1 group I member 2 | | 著者 | Focken, T, Maskos, K, Griessner, A, Krapp, S. | | 登録日 | 2019-06-26 | | 公開日 | 2019-10-02 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Identification of CNS-Penetrant Aryl Sulfonamides as Isoform-Selective NaV1.6 Inhibitors with Efficacy in Mouse Models of Epilepsy.
J.Med.Chem., 62, 2019
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