1EYY
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![BU of 1eyy by Molmil](/molmil-images/mine/1eyy) | CRYSTAL STRUCTURE OF THE NADP+ DEPENDENT ALDEHYDE DEHYDROGENASE FROM VIBRIO HARVEYI. | 分子名称: | ALDEHYDE DEHYDROGENASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Ahvazi, B, Coulombe, R, Delarge, M, Vedadi, M, Zhang, L, Meighen, E, Vrielink, A. | 登録日 | 2000-05-09 | 公開日 | 2000-05-24 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structure of the NADP+-dependent aldehyde dehydrogenase from Vibrio harveyi: structural implications for cofactor specificity and affinity. Biochem.J., 349, 2000
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3WQK
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![BU of 3wqk by Molmil](/molmil-images/mine/3wqk) | Crystal structure of Rv3378c with PO4 | 分子名称: | Diterpene synthase, PHOSPHATE ION | 著者 | Chan, H.C, Feng, X, Ko, T.P, Huang, C.H, Hu, Y, Zheng, Y, Bogue, S, Nakano, C, Hoshino, T, Zhang, L, Lv, P, Liu, W, Crick, D.C, Liang, P.H, Wang, A.H, Oldfield, E, Guo, R.T. | 登録日 | 2014-01-28 | 公開日 | 2014-02-19 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure and inhibition of tuberculosinol synthase and decaprenyl diphosphate synthase from Mycobacterium tuberculosis. J.Am.Chem.Soc., 136, 2014
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3WQM
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![BU of 3wqm by Molmil](/molmil-images/mine/3wqm) | Crystal structure of Rv3378c with inhibitor BPH-629 | 分子名称: | Diterpene synthase, MAGNESIUM ION, PHOSPHATE ION, ... | 著者 | Chan, H.C, Feng, X, Ko, T.P, Huang, C.H, Hu, Y, Zheng, Y, Bogue, S, Nakano, C, Hoshino, T, Zhang, L, Lv, P, Liu, W, Crick, D.C, Liang, P.H, Wang, A.H, Oldfield, E, Guo, R.T. | 登録日 | 2014-01-28 | 公開日 | 2014-02-26 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure and inhibition of tuberculosinol synthase and decaprenyl diphosphate synthase from Mycobacterium tuberculosis. J.Am.Chem.Soc., 136, 2014
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3WQN
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![BU of 3wqn by Molmil](/molmil-images/mine/3wqn) | Crystal structure of Rv3378c_Y51F with TPP | 分子名称: | (2E)-3-methyl-5-[(1R,2S,8aS)-1,2,5,5-tetramethyl-1,2,3,5,6,7,8,8a-octahydronaphthalen-1-yl]pent-2-en-1-yl trihydrogen diphosphate, Diterpene synthase, PHOSPHATE ION | 著者 | Chan, H.C, Feng, X, Ko, T.P, Huang, C.H, Hu, Y, Zheng, Y, Bogue, S, Nakano, C, Hoshino, T, Zhang, L, Lv, P, Liu, W, Crick, D.C, Liang, P.H, Wang, A.H, Oldfield, E, Guo, R.T. | 登録日 | 2014-01-28 | 公開日 | 2014-02-26 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structure and inhibition of tuberculosinol synthase and decaprenyl diphosphate synthase from Mycobacterium tuberculosis. J.Am.Chem.Soc., 136, 2014
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6E9C
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![BU of 6e9c by Molmil](/molmil-images/mine/6e9c) | Selenomethionine Derivative Structure of A Bacterial Homolog to Human Lysosomal Transporter, Spinster | 分子名称: | Major facilitator family transporter | 著者 | Zhou, F, Yao, D, Rao, B, Zhang, L, Cao, Y. | 登録日 | 2018-07-31 | 公開日 | 2019-08-14 | 最終更新日 | 2020-01-08 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Crystal structure of a bacterial homolog to human lysosomal transporter, spinster Sci Bull (Beijing), 64, 2019
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3WQL
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![BU of 3wql by Molmil](/molmil-images/mine/3wql) | Crystal structure of Rv3378c with Mg2+ and PPi | 分子名称: | Diterpene synthase, MAGNESIUM ION | 著者 | Chan, H.C, Feng, X, Ko, T.P, Huang, C.H, Hu, Y, Zheng, Y, Bogue, S, Nakano, C, Hoshino, T, Zhang, L, Lv, P, Liu, W, Crick, D.C, Liang, P.H, Wang, A.H, Oldfield, E, Guo, R.T. | 登録日 | 2014-01-28 | 公開日 | 2014-02-19 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure and inhibition of tuberculosinol synthase and decaprenyl diphosphate synthase from Mycobacterium tuberculosis. J.Am.Chem.Soc., 136, 2014
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5Z6P
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![BU of 5z6p by Molmil](/molmil-images/mine/5z6p) | The crystal structure of an agarase, AgWH50C | 分子名称: | B-agarase | 著者 | Mao, X, Zhou, J, Zhang, P, Zhang, L, Zhang, J, Li, Y. | 登録日 | 2018-01-24 | 公開日 | 2019-01-02 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.061 Å) | 主引用文献 | Structure-based design of agarase AgWH50C from Agarivorans gilvus WH0801 to enhance thermostability. Appl. Microbiol. Biotechnol., 103, 2019
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4WNA
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![BU of 4wna by Molmil](/molmil-images/mine/4wna) | Structure of the Nitrogenase MoFe Protein from Azotobacter vinelandii Pressurized with Xenon | 分子名称: | 3-HYDROXY-3-CARBOXY-ADIPIC ACID, FE (III) ION, FE(8)-S(7) CLUSTER, ... | 著者 | Morrison, C.N, Hoy, J.A, Zhang, L, Einsle, O, Rees, D.C. | 登録日 | 2014-10-11 | 公開日 | 2015-03-18 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Substrate Pathways in the Nitrogenase MoFe Protein by Experimental Identification of Small Molecule Binding Sites. Biochemistry, 54, 2015
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2HAP
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![BU of 2hap by Molmil](/molmil-images/mine/2hap) | STRUCTURE OF A HAP1-18/DNA COMPLEX REVEALS THAT PROTEIN/DNA INTERACTIONS CAN HAVE DIRECT ALLOSTERIC EFFECTS ON TRANSCRIPTIONAL ACTIVATION | 分子名称: | DNA (5'-D(*AP*CP*GP*CP*TP*AP*TP*TP*AP*TP*CP*GP*CP*TP*AP*TP*TP*AP*GP*T)-3'), DNA (5'-D(*AP*CP*TP*AP*AP*TP*AP*GP*CP*GP*AP*TP*AP*AP*TP*AP*GP*CP*GP*T)-3'), PROTEIN (HEME ACTIVATOR PROTEIN), ... | 著者 | King, D.A, Zhang, L, Guarente, L, Marmorstein, R. | 登録日 | 1998-09-17 | 公開日 | 1999-11-10 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure of HAP1-18-DNA implicates direct allosteric effect of protein-DNA interactions on transcriptional activation. Nat.Struct.Biol., 6, 1999
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7XSR
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![BU of 7xsr by Molmil](/molmil-images/mine/7xsr) | Structure of Craspase-target RNA | 分子名称: | CHAT domain protein, RAMP superfamily protein, RNA (34-MER), ... | 著者 | Feng, Y, Zhang, L. | 登録日 | 2022-05-15 | 公開日 | 2022-11-09 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (2.97 Å) | 主引用文献 | Target RNA activates the protease activity of Craspase to confer antiviral defense. Mol.Cell, 82, 2022
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7XSQ
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![BU of 7xsq by Molmil](/molmil-images/mine/7xsq) | Structure of the Craspase | 分子名称: | CHAT domain protein, RAMP superfamily protein, RNA (34-MER), ... | 著者 | Feng, Y, Zhang, L. | 登録日 | 2022-05-15 | 公開日 | 2022-11-09 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (2.88 Å) | 主引用文献 | Target RNA activates the protease activity of Craspase to confer antiviral defense. Mol.Cell, 82, 2022
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7XT4
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![BU of 7xt4 by Molmil](/molmil-images/mine/7xt4) | Structure of Craspase-NTR | 分子名称: | CHAT domain protein, RAMP superfamily protein, RNA (34-MER), ... | 著者 | Feng, Y, Zhang, L. | 登録日 | 2022-05-16 | 公開日 | 2022-11-09 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.08 Å) | 主引用文献 | Target RNA activates the protease activity of Craspase to confer antiviral defense. Mol.Cell, 82, 2022
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7XSO
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![BU of 7xso by Molmil](/molmil-images/mine/7xso) | |
4KYK
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![BU of 4kyk by Molmil](/molmil-images/mine/4kyk) | Crystal structure of mouse glyoxalase I complexed with indomethacin | 分子名称: | INDOMETHACIN, Lactoylglutathione lyase, ZINC ION | 著者 | Zhai, J, Yuan, M, Zhang, L, Chen, Y, Zhang, H, Chen, S, Zhao, Y. | 登録日 | 2013-05-29 | 公開日 | 2013-08-07 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Zopolrestat as a human glyoxalase I inhibitor and its structural basis. Chemmedchem, 8, 2013
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4KYH
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![BU of 4kyh by Molmil](/molmil-images/mine/4kyh) | Crystal structure of mouse glyoxalase I complexed with zopolrestat | 分子名称: | 3,4-DIHYDRO-4-OXO-3-((5-TRIFLUOROMETHYL-2-BENZOTHIAZOLYL)METHYL)-1-PHTHALAZINE ACETIC ACID, Lactoylglutathione lyase, ZINC ION | 著者 | Zhai, J, Yuan, M, Zhang, L, Chen, Y, Zhang, H, Chen, S, Zhao, Y. | 登録日 | 2013-05-29 | 公開日 | 2013-08-07 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Zopolrestat as a human glyoxalase I inhibitor and its structural basis. Chemmedchem, 8, 2013
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4R29
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![BU of 4r29 by Molmil](/molmil-images/mine/4r29) | Crystal structure of bacterial cysteine methyltransferase effector NleE | 分子名称: | CITRIC ACID, GLYCEROL, S-ADENOSYLMETHIONINE, ... | 著者 | Yao, Q, Chen, J, Hu, L, Zhang, L, Shao, F. | 登録日 | 2014-08-11 | 公開日 | 2014-12-03 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | 主引用文献 | Structure and Specificity of the Bacterial Cysteine Methyltransferase Effector NleE Suggests a Novel Substrate in Human DNA Repair Pathway. Plos Pathog., 10, 2014
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5YY5
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![BU of 5yy5 by Molmil](/molmil-images/mine/5yy5) | Structural definition of a unique neutralization epitope on the receptor-binding domain of MERS-CoV spike glycoprotein | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain, Light chain, ... | 著者 | Zhang, S, Wang, P, Zhou, P, Wang, X, Zhang, L. | 登録日 | 2017-12-08 | 公開日 | 2018-08-01 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural Definition of a Unique Neutralization Epitope on the Receptor-Binding Domain of MERS-CoV Spike Glycoprotein Cell Rep, 24, 2018
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6YNQ
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![BU of 6ynq by Molmil](/molmil-images/mine/6ynq) | Structure of SARS-CoV-2 Main Protease bound to 2-Methyl-1-tetralone. | 分子名称: | (2~{S})-2-methyl-3,4-dihydro-2~{H}-naphthalen-1-one, 3C-like proteinase, CHLORIDE ION, ... | 著者 | Guenther, S, Reinke, P, Oberthuer, D, Yefanov, O, Gelisio, L, Ginn, H, Lieske, J, Domaracky, M, Brehm, W, Rahmani Mashour, A, White, T.A, Knoska, J, Pena Esperanza, G, Koua, F, Tolstikova, A, Groessler, M, Fischer, P, Hennicke, V, Fleckenstein, H, Trost, F, Galchenkova, M, Gevorkov, Y, Li, C, Awel, S, Paulraj, L.X, Ullah, N, Falke, S, Alves Franca, B, Schwinzer, M, Brognaro, H, Werner, N, Perbandt, M, Tidow, H, Seychell, B, Beck, T, Meier, S, Doyle, J.J, Giseler, H, Melo, D, Dunkel, I, Lane, T.J, Peck, A, Saouane, S, Hakanpaeae, J, Meyer, J, Noei, H, Gribbon, P, Ellinger, B, Kuzikov, M, Wolf, M, Zhang, L, Ehrt, C, Pletzer-Zelgert, J, Wollenhaupt, J, Feiler, C, Weiss, M, Schulz, E.C, Mehrabi, P, Norton-Baker, B, Schmidt, C, Lorenzen, K, Schubert, R, Han, H, Chari, A, Fernandez Garcia, Y, Turk, D, Hilgenfeld, R, Rarey, M, Zaliani, A, Chapman, H.N, Pearson, A, Betzel, C, Meents, A. | 登録日 | 2020-04-14 | 公開日 | 2020-04-29 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | X-ray screening identifies active site and allosteric inhibitors of SARS-CoV-2 main protease. Science, 372, 2021
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6YVF
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![BU of 6yvf by Molmil](/molmil-images/mine/6yvf) | Structure of SARS-CoV-2 Main Protease bound to AZD6482. | 分子名称: | 2-[[(1R)-1-(7-methyl-2-morpholin-4-yl-4-oxidanylidene-pyrido[1,2-a]pyrimidin-9-yl)ethyl]amino]benzoic acid, 3C-like proteinase, CALCIUM ION, ... | 著者 | Guenther, S, Reinke, P, Oberthuer, D, Yefanov, O, Gelisio, L, Ginn, H, Lieske, J, Domaracky, M, Brehm, W, Rahmani Mashour, A, White, T.A, Knoska, J, Pena Esperanza, G, Koua, F, Tolstikova, A, Groessler, M, Fischer, P, Hennicke, V, Fleckenstein, H, Trost, F, Galchenkova, M, Gevorkov, Y, Li, C, Awel, S, Paulraj, L.X, Ullah, N, Falke, S, Alves Franca, B, Schwinzer, M, Brognaro, H, Werner, N, Perbandt, M, Tidow, H, Seychell, B, Beck, T, Meier, S, Doyle, J.J, Giseler, H, Melo, D, Dunkel, I, Lane, T.J, Peck, A, Saouane, S, Hakanpaeae, J, Meyer, J, Noei, H, Gribbon, P, Ellinger, B, Kuzikov, M, Wolf, M, Zhang, L, Ehrt, C, Pletzer-Zelgert, J, Wollenhaupt, J, Feiler, C, Weiss, M, Schulz, E.C, Mehrabi, P, Norton-Baker, B, Schmidt, C, Lorenzen, K, Schubert, R, Han, H, Chari, A, Fernandez Garcia, Y, Turk, D, Hilgenfeld, R, Rarey, M, Zaliani, A, Chapman, H.N, Pearson, A, Betzel, C, Meents, A. | 登録日 | 2020-04-28 | 公開日 | 2020-05-20 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | X-ray screening identifies active site and allosteric inhibitors of SARS-CoV-2 main protease. Science, 372, 2021
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5XBM
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![BU of 5xbm by Molmil](/molmil-images/mine/5xbm) | Structure of SCARB2-JL2 complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Lysosome membrane protein 2, ... | 著者 | Zhang, X, Yang, P, Wang, N, Zhang, J, Li, J, Guo, H, Yin, X, Rao, Z, Wang, X, Zhang, L. | 登録日 | 2017-03-20 | 公開日 | 2018-06-27 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.501 Å) | 主引用文献 | The binding of a monoclonal antibody to the apical region of SCARB2 blocks EV71 infection. Protein Cell, 8, 2017
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5ZMD
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![BU of 5zmd by Molmil](/molmil-images/mine/5zmd) | Crystal structure of FTO in complex with m6dA modified ssDNA | 分子名称: | Alpha-ketoglutarate-dependent dioxygenase FTO, DNA (5'-D(P*TP*CP*TP*(6MA)P*TP*AP*TP*CP*G)-3'), MANGANESE (II) ION, ... | 著者 | Zhang, X, Wei, L.H, Luo, J, Xiao, Y, Liu, J, Zhang, W, Zhang, L, Jia, G.F. | 登録日 | 2018-04-02 | 公開日 | 2019-04-10 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Structural insights into FTO's catalytic mechanism for the demethylation of multiple RNA substrates. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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5ZAT
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![BU of 5zat by Molmil](/molmil-images/mine/5zat) | |
5ZAS
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![BU of 5zas by Molmil](/molmil-images/mine/5zas) | |
6CSV
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![BU of 6csv by Molmil](/molmil-images/mine/6csv) | The structure of the Cep63-Cep152 heterotetrameric complex | 分子名称: | Centrosomal protein of 63 kDa,Centrosomal protein of 152 kDa | 著者 | Lee, E, Chen, Y, Zhang, L, Kim, T.S, Ahn, J.I, Park, J.E, Lee, K.S. | 登録日 | 2018-03-21 | 公開日 | 2019-03-27 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Molecular architecture of a cylindrical self-assembly at human centrosomes. Nat Commun, 10, 2019
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6CSU
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![BU of 6csu by Molmil](/molmil-images/mine/6csu) | The structure of the Cep63-Cep152 heterotetrameric complex | 分子名称: | Centrosomal protein of 152 kDa, Centrosomal protein of 63 kDa | 著者 | Lee, E, Chen, Y, Zhang, L, Kim, T.S, Ahn, J.I, Park, J.E, Lee, K.S. | 登録日 | 2018-03-21 | 公開日 | 2019-03-27 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Molecular architecture of a cylindrical self-assembly at human centrosomes. Nat Commun, 10, 2019
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