1DBM
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2CKB
| STRUCTURE OF THE 2C/KB/DEV8 COMPLEX | 分子名称: | ALPHA, BETA T CELL RECEPTOR, BETA-2 MICROGLOBULIN, ... | 著者 | Garcia, K.C, Degano, M, Wilson, I.A. | 登録日 | 1998-01-14 | 公開日 | 1998-04-29 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural basis of plasticity in T cell receptor recognition of a self peptide-MHC antigen. Science, 279, 1998
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3GAR
| A PH-DEPENDENT STABLIZATION OF AN ACTIVE SITE LOOP OBSERVED FROM LOW AND HIGH PH CRYSTAL STRUCTURES OF MUTANT MONOMERIC GLYCINAMIDE RIBONUCLEOTIDE TRANSFORMYLASE | 分子名称: | GLYCINAMIDE RIBONUCLEOTIDE TRANSFORMYLASE, PHOSPHATE ION | 著者 | Su, Y, Yamashita, M.M, Greasley, S.E, Mullen, C.A, Shim, J.H, Jennings, P.A, Benkovic, S.J, Wilson, I.A. | 登録日 | 1998-05-13 | 公開日 | 1998-08-12 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | A pH-dependent stabilization of an active site loop observed from low and high pH crystal structures of mutant monomeric glycinamide ribonucleotide transformylase at 1.8 to 1.9 A. J.Mol.Biol., 281, 1998
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2FX9
| Crystal structure of hiv-1 neutralizing human fab 4e10 in complex with a thioether-linked peptide encompassing the 4e10 epitope on gp41 | 分子名称: | Fab 4E10, Fragment of HIV glycoprotein gp41 | 著者 | Cardoso, R.M.F, Brunel, F.M, Ferguson, S, Burton, D.R, Dawson, P.E, Wilson, I.A. | 登録日 | 2006-02-03 | 公開日 | 2006-12-19 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural basis of enhanced binding of extended and helically constrained peptide epitopes of the broadly neutralizing HIV-1 antibody 4E10. J.Mol.Biol., 365, 2007
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3P3S
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3P3U
| Human transthyretin (TTR) complexed with 5-(2-ethoxyphenyl)-3-(pyridin-4-yl)-1,2,4-oxadiazole | 分子名称: | 4-[5-(2-ethoxyphenyl)-1,2,4-oxadiazol-3-yl]pyridine, Transthyretin | 著者 | Connelly, S, Wilson, I.A. | 登録日 | 2010-10-05 | 公開日 | 2011-08-24 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Potent kinetic stabilizers that prevent transthyretin-mediated cardiomyocyte proteotoxicity. Sci Transl Med, 3, 2011
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3P3T
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3P3R
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8ELO
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8ELQ
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8ELP
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8EQA
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1C3E
| NEW INSIGHTS INTO INHIBITOR DESIGN FROM THE CRYSTAL STRUCTURE AND NMR STUDIES OF E. COLI GAR TRANSFORMYLATE IN COMPLEX WITH BETA-GAR AND 10-FORMYL-5,8,10-TRIDEAZAFOLIC ACID. | 分子名称: | 2-{4-[2-(2-AMINO-4-HYDROXY-QUINAZOLIN-6-YL)-1-CARBOXY-ETHYL]-BENZOYLAMINO}-PENTANEDIOIC ACID, GLYCINAMIDE RIBONUCLEOTIDE, GLYCINAMIDE RIBONUCLEOTIDE TRANSFORMYLASE | 著者 | Greasley, S.E, Yamashita, M.M, Cai, H, Benkovic, S.J, Boger, D.L, Wilson, I.A. | 登録日 | 1999-07-27 | 公開日 | 1999-12-29 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | New insights into inhibitor design from the crystal structure and NMR studies of Escherichia coli GAR transformylase in complex with beta-GAR and 10-formyl-5,8,10-trideazafolic acid. Biochemistry, 38, 1999
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1C2T
| NEW INSIGHTS INTO INHIBITOR DESIGN FROM THE CRYSTAL STRUCTURE AND NMR STUDIES OF E. COLI GAR TRANSFORMYLASE IN COMPLEX WITH BETA-GAR AND 10-FORMYL-5,8,10-TRIDEAZAFOLIC ACID. | 分子名称: | 10-FORMYL-5,8,10-TRIDEAZAFOLIC ACID, GLYCINAMIDE RIBONUCLEOTIDE, GLYCINAMIDE RIBONUCLEOTIDE TRANSFORMYLASE | 著者 | Greasley, S.E, Yamashita, M.M, Cai, H, Benkovic, S.J, Boger, D.L, Wilson, I.A. | 登録日 | 1999-07-26 | 公開日 | 2000-01-05 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | New insights into inhibitor design from the crystal structure and NMR studies of Escherichia coli GAR transformylase in complex with beta-GAR and 10-formyl-5,8,10-trideazafolic acid. Biochemistry, 38, 1999
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8EQC
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8GB6
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8GB7
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8GB8
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8GB5
| Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody 25F9 | 分子名称: | 25F9 Heavy chain, 25F9 Light chain, BICINE, ... | 著者 | Yuan, M, Zhu, X, Wilson, I.A. | 登録日 | 2023-02-24 | 公開日 | 2023-05-24 | 実験手法 | X-RAY DIFFRACTION (3.35 Å) | 主引用文献 | Broadly neutralizing antibodies against sarbecoviruses generated by immunization of macaques with an AS03-adjuvanted COVID-19 vaccine. Sci Transl Med, 15, 2023
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8GBX
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8GBY
| Crystal structure of PC39-50E, an anti-HIV broadly neutralizing antibody | 分子名称: | GLYCEROL, PC39-50E Fab heavy chain, PC39-50E Fab light chain | 著者 | Murrell, S, Omorodion, O, Wilson, I.A. | 登録日 | 2023-02-28 | 公開日 | 2023-06-07 | 最終更新日 | 2023-07-12 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Antigen pressure from two founder viruses induces multiple insertions at a single antibody position to generate broadly neutralizing HIV antibodies. Plos Pathog., 19, 2023
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8GBW
| Crystal structure of PC39-23D, an anti-HIV broadly neutralizing antibody | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, PC39-23D Fab heavy chain, ... | 著者 | Murrell, S, Omorodion, O, Wilson, I.A. | 登録日 | 2023-02-28 | 公開日 | 2023-06-07 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Antigen pressure from two founder viruses induces multiple insertions at a single antibody position to generate broadly neutralizing HIV antibodies. Plos Pathog., 19, 2023
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8GC0
| Crystal structure of PC39-50L, an anti-HIV broadly neutralizing antibody | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, PC39-50L Fab heavy chain, PC39-50L Fab light chain | 著者 | Murrell, S, Omorodion, O, Wilson, I.A. | 登録日 | 2023-02-28 | 公開日 | 2023-06-07 | 最終更新日 | 2023-07-12 | 実験手法 | X-RAY DIFFRACTION (2.43 Å) | 主引用文献 | Antigen pressure from two founder viruses induces multiple insertions at a single antibody position to generate broadly neutralizing HIV antibodies. Plos Pathog., 19, 2023
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8GBV
| Crystal structure of PC39-17A, an anti-HIV broadly neutralizing antibody | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, PC39-17A Fab heavy chain, ... | 著者 | Murrell, S, Omorodion, O, Wilson, I.A. | 登録日 | 2023-02-28 | 公開日 | 2023-06-07 | 最終更新日 | 2023-07-12 | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | 主引用文献 | Antigen pressure from two founder viruses induces multiple insertions at a single antibody position to generate broadly neutralizing HIV antibodies. Plos Pathog., 19, 2023
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8GC1
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