2XIW
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![BU of 2xiw by Molmil](/molmil-images/mine/2xiw) | Crystal structure of the Sac7d-derived IgG1-binder C3-C24S | 分子名称: | CHLORIDE ION, DNA-BINDING PROTEIN 7D, SULFATE ION | 著者 | Bellinzoni, M, Colinet, S, Behar, G, Alzari, P.M, Pecorari, F. | 登録日 | 2010-07-01 | 公開日 | 2011-07-13 | 最終更新日 | 2013-04-10 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Tolerance of the Archaeal Sac7D Scaffold Protein to Alternative Library Designs: Characterization of Anti-Immunoglobulin G Affitins. Protein Eng.Des.Sel., 26, 2013
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2WAM
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![BU of 2wam by Molmil](/molmil-images/mine/2wam) | Crystal structure of Mycobacterium tuberculosis unknown function protein Rv2714 | 分子名称: | CONSERVED HYPOTHETICAL ALANINE AND LEUCINE RICH PROTEIN, GLYCEROL | 著者 | Bellinzoni, M, Grana, M, Buschiazzo, A, Miras, I, Haouz, A, Alzari, P.M. | 登録日 | 2009-02-09 | 公開日 | 2009-10-06 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structure of Mycobacterium Tuberculosis Rv2714, a Representative of a Duplicated Gene Family in Actinobacteria. Acta Crystallogr.,Sect.F, 65, 2009
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2X2B
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![BU of 2x2b by Molmil](/molmil-images/mine/2x2b) | Crystal structure of malonyl-ACP (acyl carrier protein) from Bacillus subtilis | 分子名称: | 3-{[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl]sulfanyl}-3-oxopropanoic acid, ACYL CARRIER PROTEIN, PLATINUM (II) ION | 著者 | Bellinzoni, M, Martinez, M.A, DeMendoza, D, Alzari, P.M. | 登録日 | 2010-01-12 | 公開日 | 2010-03-16 | 最終更新日 | 2011-10-12 | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | 主引用文献 | A Novel Role of Malonyl-Acp in Lipid Homeostasis. Biochemistry, 49, 2010
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2WZV
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![BU of 2wzv by Molmil](/molmil-images/mine/2wzv) | Crystal structure of the FMN-dependent nitroreductase NfnB from Mycobacterium smegmatis | 分子名称: | FLAVIN MONONUCLEOTIDE, GLYCEROL, NFNB PROTEIN, ... | 著者 | Bellinzoni, M, Manina, G, Riccardi, G, Alzari, P.M. | 登録日 | 2009-12-03 | 公開日 | 2010-07-14 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Biological and Structural Characterization of the Mycobacterium Smegmatis Nitroreductase Nfnb, and its Role in Benzothiazinone Resistance Mol.Microbiol., 77, 2010
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2WZW
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![BU of 2wzw by Molmil](/molmil-images/mine/2wzw) | Crystal structure of the FMN-dependent nitroreductase NfnB from Mycobacterium smegmatis in complex with NADPH | 分子名称: | FLAVIN MONONUCLEOTIDE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NFNB PROTEIN, ... | 著者 | Bellinzoni, M, Manina, G, Riccardi, G, Alzari, P.M. | 登録日 | 2009-12-03 | 公開日 | 2010-07-14 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Biological and Structural Characterization of the Mycobacterium Smegmatis Nitroreductase Nfnb, and its Role in Benzothiazinone Resistance Mol.Microbiol., 77, 2010
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4TUY
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![BU of 4tuy by Molmil](/molmil-images/mine/4tuy) | Tubulin-Rhizoxin complex | 分子名称: | (1R,2R,3E,5R,7R,8S,10S,13E,16R)-8-hydroxy-10-[(2S,3R,4E,6E,8E)-3-methoxy-4,8-dimethyl-9-(2-methyl-1,3-oxazol-4-yl)nona-4,6,8-trien-2-yl]-2,7-dimethyl-6,11,19-trioxatricyclo[14.3.1.0~5,7~]icosa-3,13-diene-12,18-dione, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | 著者 | Prota, A.E, Bargsten, K, Diaz, J.F, Marsh, M, Cuevas, C, Liniger, M, Neuhaus, C, Andreu, J.M, Altmann, K.H, Steinmetz, M.O. | 登録日 | 2014-06-25 | 公開日 | 2014-08-27 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | A new tubulin-binding site and pharmacophore for microtubule-destabilizing anticancer drugs. Proc.Natl.Acad.Sci.USA, 111, 2014
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3LS8
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![BU of 3ls8 by Molmil](/molmil-images/mine/3ls8) | Crystal structure of human PIK3C3 in complex with 3-[4-(4-Morpholinyl)thieno[3,2-d]pyrimidin-2-yl]-phenol | 分子名称: | 3-(4-morpholin-4-ylthieno[3,2-d]pyrimidin-2-yl)phenol, CHLORIDE ION, GLYCEROL, ... | 著者 | Tresaugues, L, Welin, M, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, I, Karlberg, T, Kotenyova, T, Kraulis, P, Moche, M, Nyman, T, Persson, C, Schuler, H, Schutz, P, Siponen, M.I, Thorsell, A.G, Van den Berg, S, Wahlberg, E, Weigelt, J, Wisniewska, M, Nordlund, P, Structural Genomics Consortium (SGC) | 登録日 | 2010-02-12 | 公開日 | 2010-03-23 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Crystal structure of human PIK3C3 in complex with 3-[4-(4-Morpholinyl)thieno[3,2-d]pyrimidin-2-yl]-phenol To be Published
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3MCF
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![BU of 3mcf by Molmil](/molmil-images/mine/3mcf) | Crystal structure of human diphosphoinositol polyphosphate phosphohydrolase 3-alpha | 分子名称: | CITRATE ANION, Diphosphoinositol polyphosphate phosphohydrolase 3-alpha, GLYCEROL | 著者 | Tresaugues, L, Welin, M, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, I, Karlberg, T, Kol, S, Kotenyova, T, Moche, M, Nyman, T, Persson, C, Schuler, H, Schutz, P, Siponen, M.I, Thorsell, A.G, van der Berg, S, Wahlberg, E, Weigelt, J, Wisniewska, M, Nordlund, P, Structural Genomics Consortium (SGC) | 登録日 | 2010-03-29 | 公開日 | 2010-04-07 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of human diphosphoinositol polyphosphate phosphohydrolase 3-alpha To be Published
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1EVP
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1EFO
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![BU of 1efo by Molmil](/molmil-images/mine/1efo) | CRYSTAL STRUCTURE OF AN ADENINE BULGE IN THE RNA CHAIN OF A DNA/RNA HYBRID, D(CTCCTCTTC)/R(GAAGAGAGAG) | 分子名称: | DNA (5'-D(*CP*TP*CP*CP*TP*CP*TP*TP*C)-3'), RNA (5'-R(*GP*AP*AP*GP*AP*GP*AP*GP*AP*G)-3') | 著者 | Sudarsanakumar, C, Xiong, Y, Sundaralingam, M. | 登録日 | 2000-02-09 | 公開日 | 2000-05-29 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of an adenine bulge in the RNA chain of a DNA.RNA hybrid, d(CTCCTCTTC).r(gaagagagag). J.Mol.Biol., 299, 2000
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9G5L
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9G2A
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![BU of 9g2a by Molmil](/molmil-images/mine/9g2a) | Staphylococcus aureus MazF in complex with nanobody 4 | 分子名称: | 3[N-MORPHOLINO]PROPANE SULFONIC ACID, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Endoribonuclease MazF, ... | 著者 | Prolic-Kalinsek, M, Zorzini, V, Haesaerts, S, Loris, R. | 登録日 | 2024-07-10 | 公開日 | 2024-07-17 | 最終更新日 | 2024-07-24 | 実験手法 | X-RAY DIFFRACTION (2.046594 Å) | 主引用文献 | Staphylococcus aureus MazF in complex with nanobody 4. To Be Published
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9G2G
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![BU of 9g2g by Molmil](/molmil-images/mine/9g2g) | Staphylococcus aureus MazF in complex with nanobody 5 | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Endoribonuclease MazF, Nanobody 5 | 著者 | Prolic-Kalinsek, M, Zorzini, V, Haesaerts, S, Loris, R. | 登録日 | 2024-07-10 | 公開日 | 2024-07-24 | 実験手法 | X-RAY DIFFRACTION (1.80048239 Å) | 主引用文献 | Nanobody-mediated activation and inhibition of Staphylococcus aureus MazF To Be Published
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9G5Z
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4ZZX
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![BU of 4zzx by Molmil](/molmil-images/mine/4zzx) | Structure of PARP2 catalytic domain bound to an isoindolinone inhibitor | 分子名称: | 2-(3-methoxypropyl)-3-oxo-2,3-dihydro-1H-isoindole-4-carboxamide, POLY [ADP-RIBOSE] POLYMERASE 2 | 著者 | Casale, E, Fasolini, M, Papeo, G, Posteri, H, Borghi, D, Busel, A.A, Caprera, F, Ciomei, M, Cirla, A, Corti, E, DAnello, M, Fasolini, M, Felder, E.R, Forte, B, Galvani, A, Isacchi, A, Khvat, A, Krasavin, M.Y, Lupi, R, Orsini, P, Perego, R, Pesenti, E, Pezzetta, D, Rainoldi, S, RiccardiSirtori, F, Scolaro, A, Sola, F, Zuccotto, F, Donati, D, Montagnoli, A. | 登録日 | 2015-04-15 | 公開日 | 2015-08-12 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Discovery of 2-[1-(4,4-Difluorocyclohexyl)Piperidin-4-Yl]-6-Fluoro-3-Oxo-2,3-Dihydro-1H-Isoindole-4-Carboxamide (Nms-P118): A Potent, Orally Available and Highly Selective Parp- 1 Inhibitor for Cancer Therapy. J.Med.Chem., 58, 2015
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2Y64
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![BU of 2y64 by Molmil](/molmil-images/mine/2y64) | Xylopentaose binding mutated (X-2 L110F) CBM4-2 Carbohydrate Binding Module from a Thermostable Rhodothermus marinus Xylanase | 分子名称: | CALCIUM ION, XYLANASE, beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose | 著者 | von Schantz, L, Hakansson, M, Logan, D.T, Walse, B, Osterlin, J, Nordberg-Karlsson, E, Ohlin, M. | 登録日 | 2011-01-19 | 公開日 | 2012-03-07 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Structural basis for carbohydrate-binding specificity--a comparative assessment of two engineered carbohydrate-binding modules. Glycobiology, 22, 2012
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9EV5
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![BU of 9ev5 by Molmil](/molmil-images/mine/9ev5) | Corynebacterium glutamicum CS176 pyruvate:quinone oxidoreductase (PQO) in complex with FAD and thiamine diphosphate-magnesium ion | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, MAGNESIUM ION, THIAMINE DIPHOSPHATE, ... | 著者 | Da Silva Lameira, C, Muenssinger, S, Yang, L, Eikmanns, B.J, Bellinzoni, M. | 登録日 | 2024-03-28 | 公開日 | 2024-08-07 | 実験手法 | X-RAY DIFFRACTION (1.863 Å) | 主引用文献 | Corynebacterium glutamicum pyruvate:quinone oxidoreductase: an enigmatic metabolic enzyme with unusual structural features. Febs J., 2024
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9EV4
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![BU of 9ev4 by Molmil](/molmil-images/mine/9ev4) | Pyruvate:quinone oxidoreductase (PQO) from Corynebacterium glutamicum CS176 | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (Cytochrome), ... | 著者 | Da Silva Lameira, C, Muenssinger, S, Yang, L, Eikmanns, B.J, Bellinzoni, M. | 登録日 | 2024-03-28 | 公開日 | 2024-08-07 | 実験手法 | X-RAY DIFFRACTION (1.474 Å) | 主引用文献 | Corynebacterium glutamicum pyruvate:quinone oxidoreductase: an enigmatic metabolic enzyme with unusual structural features. Febs J., 2024
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9EV3
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![BU of 9ev3 by Molmil](/molmil-images/mine/9ev3) | Corynebacterium glutamicum pyruvate:quinone oxidoreductase (PQO) purified from bacteria grown in acetate minimal medium | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, MAGNESIUM ION, THIAMINE DIPHOSPHATE, ... | 著者 | Da Silva Lameira, C, Muenssinger, S, Yang, L, Eikmanns, B.J, Bellinzoni, M. | 登録日 | 2024-03-28 | 公開日 | 2024-08-07 | 実験手法 | X-RAY DIFFRACTION (1.219 Å) | 主引用文献 | Corynebacterium glutamicum pyruvate:quinone oxidoreductase: an enigmatic metabolic enzyme with unusual structural features. Febs J., 2024
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9EV6
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![BU of 9ev6 by Molmil](/molmil-images/mine/9ev6) | Corynebacterium glutamicum pyruvate:quinone oxidoreductase (PQO), C-terminal truncated construct | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, MAGNESIUM ION, THIAMINE DIPHOSPHATE, ... | 著者 | Da Silva Lameira, C, Muenssinger, S, Yang, L, Eikmanns, B.J, Bellinzoni, M. | 登録日 | 2024-03-28 | 公開日 | 2024-08-07 | 実験手法 | X-RAY DIFFRACTION (1.891 Å) | 主引用文献 | Corynebacterium glutamicum pyruvate:quinone oxidoreductase: an enigmatic metabolic enzyme with unusual structural features. Febs J., 2024
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2Y6G
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![BU of 2y6g by Molmil](/molmil-images/mine/2y6g) | Cellopentaose binding mutated (X-2 L110F) CBM4-2 Carbohydrate Binding Module from a Thermostable Rhodothermus marinus Xylanase | 分子名称: | CALCIUM ION, XYLANASE, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose | 著者 | von Schantz, L, Hakansson, M, Logan, D.T, Walse, B, Osterlin, J, Nordberg-Karlsson, E, Ohlin, M. | 登録日 | 2011-01-21 | 公開日 | 2012-03-07 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Structural basis for carbohydrate-binding specificity--a comparative assessment of two engineered carbohydrate-binding modules. Glycobiology, 22, 2012
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2Y6L
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![BU of 2y6l by Molmil](/molmil-images/mine/2y6l) | Xylopentaose binding X-2 engineered mutated CBM4-2 Carbohydrate Binding Module from a Thermostable Rhodothermus marinus Xylanase | 分子名称: | CALCIUM ION, XYLANASE, beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose | 著者 | von Schantz, L, Hakansson, M, Logan, D.T, Walse, B, Osterlin, J, Nordberg-Karlsson, E, Ohlin, M. | 登録日 | 2011-01-24 | 公開日 | 2012-03-07 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.28 Å) | 主引用文献 | Structural basis for carbohydrate-binding specificity--a comparative assessment of two engineered carbohydrate-binding modules. Glycobiology, 22, 2012
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1RSV
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![BU of 1rsv by Molmil](/molmil-images/mine/1rsv) | azide complex of the diferrous E238A mutant R2 subunit of ribonucleotide reductase | 分子名称: | AZIDE ION, FE (III) ION, MERCURY (II) ION, ... | 著者 | Assarsson, M, Andersson, M.E, Hogbom, M, Persson, B.O, Sahlin, M, Barra, A.L, Sjoberg, B.M, Nordlund, P, Graslund, A. | 登録日 | 2003-12-10 | 公開日 | 2003-12-23 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Restoring proper radical generation by azide binding to the iron site of the E238A mutant R2 protein of ribonucleotide reductase from Escherichia coli. J.Biol.Chem., 276, 2001
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4ZZN
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![BU of 4zzn by Molmil](/molmil-images/mine/4zzn) | Human ERK2 in complex with an inhibitor | 分子名称: | 2-[[5-chloranyl-2-(oxan-4-ylamino)pyridin-4-yl]amino]-N-methyl-benzamide, MITOGEN-ACTIVATED PROTEIN KINASE 1, SULFATE ION | 著者 | Ward, R.A, Colclough, N, Challinor, M, Debreczeni, J.E, Eckersley, K, Fairley, G, Feron, L, Flemington, V, Graham, M.A, Greenwood, R, Hopcroft, P, Howard, T.D, James, M, Jones, C.D, Jones, C.R, Renshaw, J, Roberts, K, Snow, L, Tonge, M, Yeung, K. | 登録日 | 2015-04-10 | 公開日 | 2015-05-27 | 最終更新日 | 2015-08-26 | 実験手法 | X-RAY DIFFRACTION (1.33 Å) | 主引用文献 | Structure-Guided Design of Highly Selective and Potent Covalent Inhibitors of Erk1/2. J.Med.Chem., 58, 2015
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2M50
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![BU of 2m50 by Molmil](/molmil-images/mine/2m50) | Analysis of the structural and molecular basis of voltage-sensitive sodium channel inhibition by the spider toxin, Huwentoxin-IV (-TRTX-Hh2a). | 分子名称: | Mu-theraphotoxin-Hh2a | 著者 | Gibbs, A, Minassian, N, Flinspach, M, Wickenden, A. | 登録日 | 2013-02-12 | 公開日 | 2013-06-19 | 最終更新日 | 2023-11-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Analysis of the Structural and Molecular Basis of Voltage-sensitive Sodium Channel Inhibition by the Spider Toxin Huwentoxin-IV ( mu-TRTX-Hh2a). J.Biol.Chem., 288, 2013
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