5HLW
| Crystal structure of c-Met mutant Y1230H in complex with compound 14 | 分子名称: | 1-[2-(1-ethylpiperidin-4-yl)ethyl]-3-(6-{[6-(thiophen-2-yl)[1,2,4]triazolo[4,3-b]pyridazin-3-yl]sulfanyl}-1,3-benzothiazol-2-yl)urea, CHLORIDE ION, Hepatocyte growth factor receptor | 著者 | Vallee, F, Pouzieux, S, Marquette, J.P, Houtmann, J. | 登録日 | 2016-01-15 | 公開日 | 2016-11-23 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | 主引用文献 | Discovery and Pharmacokinetic and Pharmacological Properties of the Potent and Selective MET Kinase Inhibitor 1-{6-[6-(4-Fluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazin-3-ylsulfanyl]benzothiazol-2-yl}-3-(2-morpholin-4-ylethyl)urea (SAR125844). J.Med.Chem., 59, 2016
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5KPN
| Structure of human PARP1 catalytic domain bound to a quinazoline-2,4(1H,3H)-dione inhibitor | 分子名称: | 1-[[4-fluoranyl-3-(3-oxidanylidene-4-propyl-piperazin-1-yl)carbonyl-phenyl]methyl]quinazoline-2,4-dione, Poly [ADP-ribose] polymerase 1 | 著者 | Cao, R, Wang, Y.L, Zhou, J, Yao, H.P, Huang, N, Xu, B.L. | 登録日 | 2016-07-05 | 公開日 | 2016-12-21 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure of human PARP1 catalytic domain bound to a quinazoline-2,4(1H,3H)-dione inhibitor To Be Published
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6VRG
| Structure of HIV-1 integrase with native amino-terminal sequence | 分子名称: | Integrase, PHOSPHATE ION, POTASSIUM ION, ... | 著者 | Eilers, G, Gupta, K, Allen, A, Zhou, J, Hwang, Y, Cory, M, Bushman, F.D, Van Duyne, G.D. | 登録日 | 2020-02-07 | 公開日 | 2020-09-09 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Influence of the amino-terminal sequence on the structure and function of HIV integrase. Retrovirology, 17, 2020
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5X5R
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1C15
| SOLUTION STRUCTURE OF APAF-1 CARD | 分子名称: | APOPTOTIC PROTEASE ACTIVATING FACTOR 1 | 著者 | Zhou, P, Chou, J, Olea, R.S, Yuan, J, Wagner, G. | 登録日 | 1999-07-20 | 公開日 | 1999-09-20 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of Apaf-1 CARD and its interaction with caspase-9 CARD: a structural basis for specific adaptor/caspase interaction. Proc.Natl.Acad.Sci.USA, 96, 1999
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5KOC
| Pavine N-methyltransferase in complex with S-adenosylmethionine pH 7 | 分子名称: | Pavine N-methyltransferase, S-ADENOSYLMETHIONINE | 著者 | Torres, M.A, Hoffarth, E, Savtchouk, J, Chen, X, Morris, J, Facchini, P.J, Ng, K.K.S. | 登録日 | 2016-06-30 | 公開日 | 2016-09-07 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.293 Å) | 主引用文献 | Structural and Functional Studies of Pavine N-Methyltransferase from Thalictrum flavum Reveal Novel Insights into Substrate Recognition and Catalytic Mechanism. J.Biol.Chem., 291, 2016
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5KOK
| Pavine N-methyltransferase in complex with Tetrahydropapaverine and S-adenosylhomocysteine pH 7.25 | 分子名称: | (1~{R})-1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline, (1~{S})-1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline, Pavine N-methyltransferase, ... | 著者 | Torres, M.A, Hoffarth, E, Eugenio, L, Savtchouk, J, Chen, X, Morris, J, Facchini, P.J, Ng, K.K.S. | 登録日 | 2016-06-30 | 公開日 | 2016-09-07 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.792 Å) | 主引用文献 | Structural and Functional Studies of Pavine N-Methyltransferase from Thalictrum flavum Reveal Novel Insights into Substrate Recognition and Catalytic Mechanism. J.Biol.Chem., 291, 2016
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5KPC
| Pavine N-methyltransferase H206A mutant in complex with S-adenosylmethionine pH 6 | 分子名称: | Pavine N-methyltransferase, S-ADENOSYLMETHIONINE | 著者 | Torres, M.A, Hoffarth, E, Eugenio, L, Savtchouk, J, Chen, X, Morris, J, Facchini, P.J, Ng, K.K.S. | 登録日 | 2016-07-03 | 公開日 | 2016-09-07 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural and Functional Studies of Pavine N-Methyltransferase from Thalictrum flavum Reveal Novel Insights into Substrate Recognition and Catalytic Mechanism. J.Biol.Chem., 291, 2016
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5KN4
| Pavine N-methyltransferase apoenzyme pH 6.0 | 分子名称: | Pavine N-methyltransferase | 著者 | Torres, M.A, Hoffarth, E, Eugenio, L, Savtchouk, J, Chen, X, Morris, J, Facchini, P.J, Ng, K.K.S. | 登録日 | 2016-06-27 | 公開日 | 2016-09-07 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Structural and Functional Studies of Pavine N-Methyltransferase from Thalictrum flavum Reveal Novel Insights into Substrate Recognition and Catalytic Mechanism. J.Biol.Chem., 291, 2016
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5KPG
| Pavine N-methyltransferase in complex with S-adenosylhomocysteine pH 7 | 分子名称: | Pavine N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE | 著者 | Torres, M.A, Hoffarth, E, Eugenio, L, Savtchouk, J, Chen, X, Morris, J, Facchini, P.J, Ng, K.K.S. | 登録日 | 2016-07-04 | 公開日 | 2016-09-07 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural and Functional Studies of Pavine N-Methyltransferase from Thalictrum flavum Reveal Novel Insights into Substrate Recognition and Catalytic Mechanism. J.Biol.Chem., 291, 2016
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3CM8
| A RNA polymerase subunit structure from virus | 分子名称: | Polymerase acidic protein, peptide from RNA-directed RNA polymerase catalytic subunit | 著者 | He, X, Zhou, J, Zeng, Z, Ma, J, Zhang, R, Rao, Z, Liu, Y. | 登録日 | 2008-03-21 | 公開日 | 2008-07-15 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.899 Å) | 主引用文献 | Crystal structure of the polymerase PAC-PB1N complex from an avian influenza H5N1 virus Nature, 454, 2008
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5H2T
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5HSI
| Crystal structure of tyrosine decarboxylase at 1.73 Angstroms resolution | 分子名称: | MAGNESIUM ION, Putative decarboxylase | 著者 | Ni, Y, Zhou, J, Zhu, H, Zhang, K. | 登録日 | 2016-01-25 | 公開日 | 2016-09-21 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.732 Å) | 主引用文献 | Crystal structure of tyrosine decarboxylase and identification of key residues involved in conformational swing and substrate binding Sci Rep, 6, 2016
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5H5X
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5GCN
| CATALYTIC DOMAIN OF TETRAHYMENA GCN5 HISTONE ACETYLTRANSFERASE IN COMPLEX WITH COENZYME A | 分子名称: | COENZYME A, HISTONE ACETYLTRANSFERASE GCN5 | 著者 | Lin, Y, Fletcher, C.M, Zhou, J, Allis, C.D, Wagner, G. | 登録日 | 1999-03-24 | 公開日 | 1999-07-19 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the catalytic domain of GCN5 histone acetyltransferase bound to coenzyme A Nature, 400, 1999
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5MXH
| Photorhabdus asymbiotica lectin (PHL) in complex with D-galactose | 分子名称: | CHLORIDE ION, MAGNESIUM ION, Photorhabdus asymbiotica lectin PHL, ... | 著者 | Jancarikova, G, Houser, J, Demo, G, Wimmerova, M. | 登録日 | 2017-01-23 | 公開日 | 2017-08-09 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Characterization of novel bangle lectin from Photorhabdus asymbiotica with dual sugar-binding specificity and its effect on host immunity. PLoS Pathog., 13, 2017
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5MXG
| Photorhabdus asymbiotica lectin (PHL) in complex with blood group H trisaccharide | 分子名称: | Photorhabdus asymbiotica lectin PHL, SODIUM ION, alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Jancarikova, G, Houser, J, Demo, G, Wimmerova, M. | 登録日 | 2017-01-23 | 公開日 | 2017-08-09 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Characterization of novel bangle lectin from Photorhabdus asymbiotica with dual sugar-binding specificity and its effect on host immunity. PLoS Pathog., 13, 2017
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5MXE
| Photorhabdus asymbiotica lectin (PHL) in free form | 分子名称: | CHLORIDE ION, Photorhabdus asymbiotica lectin PHL, SODIUM ION | 著者 | Jancarikova, G, Houser, J, Demo, G, Wimmerova, M. | 登録日 | 2017-01-23 | 公開日 | 2017-08-09 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Characterization of novel bangle lectin from Photorhabdus asymbiotica with dual sugar-binding specificity and its effect on host immunity. PLoS Pathog., 13, 2017
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4FTW
| Crystal structure of a carboxyl esterase N110C/L145H at 2.3 angstrom resolution | 分子名称: | 3-CYCLOHEXYLPROPYL 4-O-ALPHA-D-GLUCOPYRANOSYL-BETA-D-GLUCOPYRANOSIDE, CHLORIDE ION, PIPERAZINE-N,N'-BIS(2-ETHANESULFONIC ACID), ... | 著者 | Wu, L, Ma, J, Zhou, J, Yu, H. | 登録日 | 2012-06-28 | 公開日 | 2012-10-03 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Enhanced enantioselectivity of a carboxyl esterase from Rhodobacter sphaeroides by directed evolution. Appl.Microbiol.Biotechnol., 97, 2013
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5MXF
| Photorhabdus asymbiotica lectin (PHL) in complex with alpha-methyl fucoside | 分子名称: | CHLORIDE ION, Photorhabdus asymbiotica lectin PHL, SODIUM ION, ... | 著者 | Jancarikova, G, Houser, J, Demo, G, Wimmerova, M. | 登録日 | 2017-01-23 | 公開日 | 2017-08-09 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Characterization of novel bangle lectin from Photorhabdus asymbiotica with dual sugar-binding specificity and its effect on host immunity. PLoS Pathog., 13, 2017
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4FHZ
| Crystal structure of a carboxyl esterase at 2.0 angstrom resolution | 分子名称: | DI(HYDROXYETHYL)ETHER, Phospholipase/Carboxylesterase, SODIUM ION | 著者 | Wu, L, Ma, J, Zhou, J, Yu, H. | 登録日 | 2012-06-07 | 公開日 | 2012-10-03 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Enhanced enantioselectivity of a carboxyl esterase from Rhodobacter sphaeroides by directed evolution. Appl.Microbiol.Biotechnol., 97, 2013
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4HP5
| The crystal structure of isomaltulose synthase mutant E295A from Erwinia rhapontici NX5 in complex with D-glucose | 分子名称: | CALCIUM ION, GLYCEROL, Sucrose isomerase, ... | 著者 | Xu, Z, Li, S, Xu, H, Zhou, J. | 登録日 | 2012-10-23 | 公開日 | 2013-11-13 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The crystal structure of isomaltulose synthase mutant E295A from Erwinia rhapontici NX5 in complex with D-glucose to be published
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5LRP
| Mopeia Virus Exonuclease domain complexed with Magnesium | 分子名称: | MAGNESIUM ION, Nucleoprotein, ZINC ION | 著者 | Yekwa, E.L, Khourieh, J, Canard, B, Ferron, F. | 登録日 | 2016-08-19 | 公開日 | 2017-07-05 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.941 Å) | 主引用文献 | Activity inhibition and crystal polymorphism induced by active-site metal swapping. Acta Crystallogr D Struct Biol, 73, 2017
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6T96
| Photorhabdus laumondii subsp. laumondii lectin PLL3 | 分子名称: | Lectin PLL3, SODIUM ION | 著者 | Melicher, F, Houser, J, Fujdiarova, E, Faltinek, L, Wimmerova, M. | 登録日 | 2019-10-26 | 公開日 | 2019-12-25 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Lectin PLL3, a Novel Monomeric Member of the Seven-Bladed beta-Propeller Lectin Family. Molecules, 24, 2019
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4LK2
| Crystal structure of RNA splicing effector Prp5 | 分子名称: | NICKEL (II) ION, Pre-mRNA-processing ATP-dependent RNA helicase PRP5 | 著者 | Zhang, Z.-M, Li, J, Yang, F, Xu, Y, Zhou, J. | 登録日 | 2013-07-05 | 公開日 | 2013-12-11 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | 主引用文献 | Crystal structure of Prp5p reveals interdomain interactions that impact spliceosome assembly. Cell Rep, 5, 2013
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