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6WNA
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BU of 6wna by Molmil
Next generation monomeric IgG4 Fc
分子名称: Beta-2-microglobulin, IgG receptor FcRn large subunit p51, Immunoglobulin heavy constant gamma 4, ...
著者Oganesyan, V.Y, Shan, L, van Dyk, N, Dall'Acqua, W.F.
登録日2020-04-22
公開日2021-09-15
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献In vivo pharmacokinetic enhancement of monomeric Fc and monovalent bispecific designs through structural guidance.
Commun Biol, 4, 2021
6WOL
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BU of 6wol by Molmil
Next generation monomeric IgG4 Fc bound to neonatal Fc receptor
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, IgG receptor FcRn large subunit p51, ...
著者Oganesyan, V.Y, Shan, L, van Dyk, N, Dall'Acqua, W.F.
登録日2020-04-24
公開日2021-09-15
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献In vivo pharmacokinetic enhancement of monomeric Fc and monovalent bispecific designs through structural guidance.
Commun Biol, 4, 2021
8FD2
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BU of 8fd2 by Molmil
Cryo-EM structure of Cascade complex in type I-B CAST system
分子名称: A Type I-B CRISPR-associated protein Cas5, RNA, Type I-B CRISPR-associated protein Cas11, ...
著者Chang, L, Wang, S.
登録日2022-12-01
公開日2023-08-09
最終更新日2024-01-31
実験手法ELECTRON MICROSCOPY (3.65 Å)
主引用文献Molecular mechanism for Tn7-like transposon recruitment by a type I-B CRISPR effector.
Cell, 186, 2023
7BIO
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BU of 7bio by Molmil
Crystal structure of monooxygenase RslO4 from Streptomyces bottropensis
分子名称: ACETATE ION, ETHANOL, Monooxygenase/putative anthronoxygenase, ...
著者Zhang, L, Zuo, C, Alali, A, Bechthold, A, Einsle, O.
登録日2021-01-12
公開日2021-01-20
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.795 Å)
主引用文献Biosynthesis of the Tricyclic Aromatic Type II Polyketide Rishirilide: New Potential Third Ring Oxygenation after Three Cyclization Steps.
Mol Biotechnol., 63, 2021
5YVF
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BU of 5yvf by Molmil
Crystal structure of BFA1
分子名称: BFA1
著者Pu, H, Zhang, L, Duan, Z.K, Peng, L.W, Liu, L.
登録日2017-11-25
公開日2018-08-08
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.804 Å)
主引用文献Nucleus-Encoded Protein BFA1 Promotes Efficient Assembly of the Chloroplast ATP Synthase Coupling Factor 1.
Plant Cell, 30, 2018
6CJK
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BU of 6cjk by Molmil
Anti HIV Fab 10A
分子名称: ACETATE ION, GLYCEROL, Immunoglobulin Fab heavy chain, ...
著者Hangartner, L, Ward, A.B, Wilson, I.A, Oyen, D.
登録日2018-02-26
公開日2018-08-15
最終更新日2019-12-18
実験手法X-RAY DIFFRACTION (1.795 Å)
主引用文献Electron-Microscopy-Based Epitope Mapping Defines Specificities of Polyclonal Antibodies Elicited during HIV-1 BG505 Envelope Trimer Immunization.
Immunity, 49, 2018
7BIP
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BU of 7bip by Molmil
Crystal structure of monooxygenase RslO1 from Streptomyces bottropensis
分子名称: 1,2-ETHANEDIOL, 3,6,9,12,15,18,21,24,27-NONAOXANONACOSANE-1,29-DIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
著者Zhang, L, Zuo, C, Bechthold, A, Einsle, O.
登録日2021-01-12
公開日2021-01-20
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Biosynthesis of the Tricyclic Aromatic Type II Polyketide Rishirilide: New Potential Third Ring Oxygenation after Three Cyclization Steps.
Mol Biotechnol., 63, 2021
5YVD
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BU of 5yvd by Molmil
Structural and biochemical characterization of endoribonuclease Nsp15 encoded by Middle East Respiratory Syndrome Coronavirus
分子名称: GLYCEROL, Nsp15
著者Yan, L, Zhang, L.
登録日2017-11-24
公開日2018-08-22
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural and Biochemical Characterization of Endoribonuclease Nsp15 Encoded by Middle East Respiratory Syndrome Coronavirus.
J. Virol., 92, 2018
3DP1
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BU of 3dp1 by Molmil
Crystal structure of (3R)-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ) from Helicobacter pylori in complex with compound 3n
分子名称: (3R)-hydroxymyristoyl-acyl carrier protein dehydratase, BENZAMIDINE, CHLORIDE ION, ...
著者Zhang, L, He, L, Liu, X, Liu, H, Shen, X, Jiang, H.
登録日2008-07-07
公開日2009-05-05
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Discovering potent inhibitors against the beta-hydroxyacyl-acyl carrier protein dehydratase (FabZ) of Helicobacter pylori: structure-based design, synthesis, bioassay, and crystal structure determination.
J.Med.Chem., 52, 2009
3DP0
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BU of 3dp0 by Molmil
Crystal structure of (3R)-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ) from Helicobacter pylori in complex with compound 3m
分子名称: (3R)-hydroxymyristoyl-acyl carrier protein dehydratase, BENZAMIDINE, CHLORIDE ION, ...
著者Zhang, L, He, L, Liu, X, Liu, H, Shen, X, Jiang, H.
登録日2008-07-07
公開日2009-05-05
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Discovering potent inhibitors against the beta-hydroxyacyl-acyl carrier protein dehydratase (FabZ) of Helicobacter pylori: structure-based design, synthesis, bioassay, and crystal structure determination.
J.Med.Chem., 52, 2009
3DP3
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BU of 3dp3 by Molmil
Crystal structure of (3R)-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ) from Helicobacter pylori in complex with compound 3q
分子名称: (3R)-hydroxymyristoyl-acyl carrier protein dehydratase, 4-tert-butyl-N'-[(1E)-(3,5-dibromo-2,4-dihydroxyphenyl)methylidene]benzohydrazide, BENZAMIDINE, ...
著者Zhang, L, He, L, Liu, X, Liu, H, Shen, X, Jiang, H.
登録日2008-07-07
公開日2009-05-05
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Discovering potent inhibitors against the beta-hydroxyacyl-acyl carrier protein dehydratase (FabZ) of Helicobacter pylori: structure-based design, synthesis, bioassay, and crystal structure determination.
J.Med.Chem., 52, 2009
3ED0
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BU of 3ed0 by Molmil
Crystal structure of (3R)-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ) from Helicobacter pylori in complex with emodin
分子名称: (3R)-hydroxymyristoyl-acyl carrier protein dehydratase, 3-METHYL-1,6,8-TRIHYDROXYANTHRAQUINONE, BENZAMIDINE, ...
著者Zhang, L, Zhang, H, Liu, W, Guo, Y, Shen, X, Jiang, H.
登録日2008-09-02
公開日2009-07-21
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Emodin targets the beta-hydroxyacyl-acyl carrier protein dehydratase from Helicobacter pylori: enzymatic inhibition assay with crystal structural and thermodynamic characterization
BMC MICROBIOL., 9, 2009
3DP2
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BU of 3dp2 by Molmil
Crystal structure of (3R)-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ) from Helicobacter pylori in complex with compound 3j
分子名称: (3R)-hydroxymyristoyl-acyl carrier protein dehydratase, 4-bromo-N'-[(1E)-(3,5-dibromo-2,4-dihydroxyphenyl)methylidene]benzohydrazide, BENZAMIDINE, ...
著者Zhang, L, He, L, Liu, X, Liu, H, Shen, X, Jiang, H.
登録日2008-07-07
公開日2009-05-05
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Discovering potent inhibitors against the beta-hydroxyacyl-acyl carrier protein dehydratase (FabZ) of Helicobacter pylori: structure-based design, synthesis, bioassay, and crystal structure determination.
J.Med.Chem., 52, 2009
4BJ0
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BU of 4bj0 by Molmil
Xyloglucan binding module (CBM4-2 X2-L110F) in complex with branched xyloses
分子名称: CALCIUM ION, XYLANASE, alpha-D-glucopyranose, ...
著者Schantz, L, Hakansson, M, Logan, D.T, Nordberg-Karlsson, E, Ohlin, M.
登録日2013-04-15
公開日2014-04-23
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献Carbohydrate Binding Module Recognition of Xyloglucan Defined by Polar Contacts with Branching Xyloses and Ch-Pi Interactions.
Proteins, 82, 2014
3DOZ
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BU of 3doz by Molmil
Crystal structure of (3R)-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ) from Helicobacter pylori in complex with compound 3k
分子名称: (3R)-hydroxymyristoyl-acyl carrier protein dehydratase, 3-bromo-N'-[(1E)-(3,5-dibromo-2,4-dihydroxyphenyl)methylidene]benzohydrazide, BENZAMIDINE, ...
著者Zhang, L, He, L, Liu, X, Liu, H, Shen, X, Jiang, H.
登録日2008-07-07
公開日2009-05-05
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Discovering potent inhibitors against the beta-hydroxyacyl-acyl carrier protein dehydratase (FabZ) of Helicobacter pylori: structure-based design, synthesis, bioassay, and crystal structure determination.
J.Med.Chem., 52, 2009
3DOY
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BU of 3doy by Molmil
Crystal structure of (3R)-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ) from Helicobacter pylori in complex with compound 3i
分子名称: (3R)-hydroxymyristoyl-acyl carrier protein dehydratase, 4-chloro-N'-[(1E)-(3,5-dibromo-2,4-dihydroxyphenyl)methylidene]benzohydrazide, BENZAMIDINE, ...
著者Zhang, L, He, L, Liu, X, Liu, H, Shen, X, Jiang, H.
登録日2008-07-07
公開日2009-05-05
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Discovering potent inhibitors against the beta-hydroxyacyl-acyl carrier protein dehydratase (FabZ) of Helicobacter pylori: structure-based design, synthesis, bioassay, and crystal structure determination.
J.Med.Chem., 52, 2009
7ELM
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BU of 7elm by Molmil
Structure of Csy-AcrIF24
分子名称: AcrIF24, CRISPR type I-F/YPEST-associated protein Csy2, CRISPR-associated protein Csy3, ...
著者Zhang, L, Feng, Y.
登録日2021-04-12
公開日2022-04-20
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (2.88 Å)
主引用文献Insights into the inhibition of type I-F CRISPR-Cas system by a multifunctional anti-CRISPR protein AcrIF24.
Nat Commun, 13, 2022
7ELN
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BU of 7eln by Molmil
Structure of Csy-AcrIF24-dsDNA
分子名称: 54-MER DNA, AcrIF24, CRISPR type I-F/YPEST-associated protein Csy2, ...
著者Zhang, L, Feng, Y.
登録日2021-04-12
公開日2022-04-20
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Insights into the inhibition of type I-F CRISPR-Cas system by a multifunctional anti-CRISPR protein AcrIF24.
Nat Commun, 13, 2022
4JEK
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BU of 4jek by Molmil
Structure of dibenzothiophene monooxygenase (DszC) from Rhodococcus erythropolis
分子名称: Dibenzothiophene desulfurization enzyme C
著者Zhang, L, Duan, X.L, Zhou, D.M, Li, X.
登録日2013-02-27
公開日2013-09-18
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystallization and preliminary structural analysis of dibenzothiophene monooxygenase (DszC) from Rhodococcus erythropolis
Acta Crystallogr.,Sect.F, 69, 2013
6JV3
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BU of 6jv3 by Molmil
Crystal structure of 5-hydoxylmethylcytosine containing decamer dsDNA
分子名称: DNA (5'-D(*CP*CP*AP*GP*(5HC)P*GP*CP*TP*GP*G)-3')
著者Zhang, L, Wang, Y.X.
登録日2019-04-15
公開日2019-07-31
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.851 Å)
主引用文献Thymine DNA glycosylase recognizes the geometry alteration of minor grooves induced by 5-formylcytosine and 5-carboxylcytosine.
Chem Sci, 10, 2019
6JV5
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BU of 6jv5 by Molmil
Crystal structure of 5-methylcytosine containing decamer dsDNA
分子名称: DNA (5'-D(*CP*CP*AP*GP*(5CM)P*GP*CP*TP*GP*G)-3')
著者Zhang, L, Wang, Y.X.
登録日2019-04-15
公開日2019-07-31
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.401 Å)
主引用文献Thymine DNA glycosylase recognizes the geometry alteration of minor grooves induced by 5-formylcytosine and 5-carboxylcytosine.
Chem Sci, 10, 2019
4O0U
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BU of 4o0u by Molmil
Crystal structures of human kinase Aurora A
分子名称: ADENOSINE, Aurora kinase A
著者Wang, J, Zhang, L, Ding, J.
登録日2013-12-14
公開日2014-12-17
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Functional Role of Conserved HxD-histidine in the Catalytic Core of Protein Kinases
To be Published
7EQG
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BU of 7eqg by Molmil
Structure of Csy-AcrIF5
分子名称: AcrIF5, CRISPR type I-F/YPEST-associated protein Csy2, CRISPR-associated protein Csy3, ...
著者Zhang, L, Feng, Y.
登録日2021-05-01
公開日2022-03-09
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献AcrIF5 specifically targets DNA-bound CRISPR-Cas surveillance complex for inhibition.
Nat.Chem.Biol., 18, 2022
7WE6
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BU of 7we6 by Molmil
Structure of Csy-AcrIF24-dsDNA
分子名称: AcrIF24, CRISPR type I-F/YPEST-associated protein Csy2, CRISPR-associated protein Csy3, ...
著者Zhang, L, Feng, Y.
登録日2021-12-22
公開日2022-04-20
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Insights into the inhibition of type I-F CRISPR-Cas system by a multifunctional anti-CRISPR protein AcrIF24.
Nat Commun, 13, 2022
7VS3
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BU of 7vs3 by Molmil
The crystal structure of rat calcium-dependent activator protein for secretion (CAPS) C2PH
分子名称: Calcium-dependent secretion activator 1, SULFATE ION
著者Zhou, H, Wei, Z.Q, Zhang, L, Ren, Y.J, Ma, C.
登録日2021-10-25
公開日2023-02-15
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.595 Å)
主引用文献The C 2 and PH domains of CAPS constitute an effective PI(4,5)P2-binding unit essential for Ca 2+ -regulated exocytosis.
Structure, 31, 2023

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