3DOY
| Crystal structure of (3R)-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ) from Helicobacter pylori in complex with compound 3i | 分子名称: | (3R)-hydroxymyristoyl-acyl carrier protein dehydratase, 4-chloro-N'-[(1E)-(3,5-dibromo-2,4-dihydroxyphenyl)methylidene]benzohydrazide, BENZAMIDINE, ... | 著者 | Zhang, L, He, L, Liu, X, Liu, H, Shen, X, Jiang, H. | 登録日 | 2008-07-07 | 公開日 | 2009-05-05 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Discovering potent inhibitors against the beta-hydroxyacyl-acyl carrier protein dehydratase (FabZ) of Helicobacter pylori: structure-based design, synthesis, bioassay, and crystal structure determination. J.Med.Chem., 52, 2009
|
|
3ED0
| Crystal structure of (3R)-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ) from Helicobacter pylori in complex with emodin | 分子名称: | (3R)-hydroxymyristoyl-acyl carrier protein dehydratase, 3-METHYL-1,6,8-TRIHYDROXYANTHRAQUINONE, BENZAMIDINE, ... | 著者 | Zhang, L, Zhang, H, Liu, W, Guo, Y, Shen, X, Jiang, H. | 登録日 | 2008-09-02 | 公開日 | 2009-07-21 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Emodin targets the beta-hydroxyacyl-acyl carrier protein dehydratase from Helicobacter pylori: enzymatic inhibition assay with crystal structural and thermodynamic characterization BMC MICROBIOL., 9, 2009
|
|
5B0K
| Structure of MoeN5-Sso7d fusion protein in complex with beta-decyl maltoside | 分子名称: | DECYL-BETA-D-MALTOPYRANOSIDE, MoeN5,DNA-binding protein 7d | 著者 | Ko, T.-P, Zhang, L, Chen, C.-C, Guo, R.-T. | 登録日 | 2015-10-30 | 公開日 | 2016-03-23 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Moenomycin Biosynthesis: Structure and Mechanism of Action of the Prenyltransferase MoeN5. Angew.Chem.Int.Ed.Engl., 55, 2016
|
|
3DP3
| Crystal structure of (3R)-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ) from Helicobacter pylori in complex with compound 3q | 分子名称: | (3R)-hydroxymyristoyl-acyl carrier protein dehydratase, 4-tert-butyl-N'-[(1E)-(3,5-dibromo-2,4-dihydroxyphenyl)methylidene]benzohydrazide, BENZAMIDINE, ... | 著者 | Zhang, L, He, L, Liu, X, Liu, H, Shen, X, Jiang, H. | 登録日 | 2008-07-07 | 公開日 | 2009-05-05 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Discovering potent inhibitors against the beta-hydroxyacyl-acyl carrier protein dehydratase (FabZ) of Helicobacter pylori: structure-based design, synthesis, bioassay, and crystal structure determination. J.Med.Chem., 52, 2009
|
|
3DP2
| Crystal structure of (3R)-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ) from Helicobacter pylori in complex with compound 3j | 分子名称: | (3R)-hydroxymyristoyl-acyl carrier protein dehydratase, 4-bromo-N'-[(1E)-(3,5-dibromo-2,4-dihydroxyphenyl)methylidene]benzohydrazide, BENZAMIDINE, ... | 著者 | Zhang, L, He, L, Liu, X, Liu, H, Shen, X, Jiang, H. | 登録日 | 2008-07-07 | 公開日 | 2009-05-05 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Discovering potent inhibitors against the beta-hydroxyacyl-acyl carrier protein dehydratase (FabZ) of Helicobacter pylori: structure-based design, synthesis, bioassay, and crystal structure determination. J.Med.Chem., 52, 2009
|
|
7YDX
| Crystal structure of human RIPK1 kinase domain in complex with compound RI-962 | 分子名称: | 1-methyl-5-[2-(2-methylpropanoylamino)-[1,2,4]triazolo[1,5-a]pyridin-7-yl]-N-[(1S)-1-phenylethyl]indole-3-carboxamide, IODIDE ION, Receptor-interacting serine/threonine-protein kinase 1 | 著者 | Zhang, L, Wang, Y, Li, Y, Wu, C, Luo, X, Wang, T, Lei, J, Yang, S. | 登録日 | 2022-07-04 | 公開日 | 2023-04-19 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.642 Å) | 主引用文献 | Generative deep learning enables the discovery of a potent and selective RIPK1 inhibitor. Nat Commun, 13, 2022
|
|
7BVH
| Crystal structure of arabinosyltransferase EmbC2-AcpM2 complex from Mycobacterium smegmatis complexed with di-arabinose | 分子名称: | CALCIUM ION, Integral membrane indolylacetylinositol arabinosyltransferase EmbC, Meromycolate extension acyl carrier protein, ... | 著者 | Zhao, Y, Zhang, L, Wu, L.J, Wang, Q, Li, J, Besra, G.S, Rao, Z.H. | 登録日 | 2020-04-10 | 公開日 | 2020-04-29 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Structures of cell wall arabinosyltransferases with the anti-tuberculosis drug ethambutol. Science, 368, 2020
|
|
5YVF
| Crystal structure of BFA1 | 分子名称: | BFA1 | 著者 | Pu, H, Zhang, L, Duan, Z.K, Peng, L.W, Liu, L. | 登録日 | 2017-11-25 | 公開日 | 2018-08-08 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.804 Å) | 主引用文献 | Nucleus-Encoded Protein BFA1 Promotes Efficient Assembly of the Chloroplast ATP Synthase Coupling Factor 1. Plant Cell, 30, 2018
|
|
5YVD
| |
2BKL
| Structural and Mechanistic Analysis of Two Prolyl Endopeptidases: Role of Inter-Domain Dynamics in Catalysis and Specificity | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, N-[(BENZYLOXY)CARBONYL]-L-ALANYL-L-PROLINE, PROLYL ENDOPEPTIDASE, ... | 著者 | Khosla, C, Shan, L, Mathews, I.I. | 登録日 | 2005-02-16 | 公開日 | 2005-03-09 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structural and Mechanistic Analysis of Two Prolyl Endopeptidases: Role of Interdomain Dynamics in Catalysis and Specificity Proc.Natl.Acad.Sci.USA, 102, 2005
|
|
7WE6
| Structure of Csy-AcrIF24-dsDNA | 分子名称: | AcrIF24, CRISPR type I-F/YPEST-associated protein Csy2, CRISPR-associated protein Csy3, ... | 著者 | Zhang, L, Feng, Y. | 登録日 | 2021-12-22 | 公開日 | 2022-04-20 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Insights into the inhibition of type I-F CRISPR-Cas system by a multifunctional anti-CRISPR protein AcrIF24. Nat Commun, 13, 2022
|
|
7ZNQ
| ABC transporter complex NosDFYL in GDN | 分子名称: | COPPER (II) ION, Copper-binding lipoprotein NosL, MAGNESIUM ION, ... | 著者 | Zhang, L, Mueller, C, Zipfel, S, Chami, M, Einsle, O. | 登録日 | 2022-04-21 | 公開日 | 2022-08-03 | 最終更新日 | 2022-10-26 | 実験手法 | ELECTRON MICROSCOPY (3.04 Å) | 主引用文献 | Molecular interplay of an assembly machinery for nitrous oxide reductase. Nature, 608, 2022
|
|
7ELM
| Structure of Csy-AcrIF24 | 分子名称: | AcrIF24, CRISPR type I-F/YPEST-associated protein Csy2, CRISPR-associated protein Csy3, ... | 著者 | Zhang, L, Feng, Y. | 登録日 | 2021-04-12 | 公開日 | 2022-04-20 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (2.88 Å) | 主引用文献 | Insights into the inhibition of type I-F CRISPR-Cas system by a multifunctional anti-CRISPR protein AcrIF24. Nat Commun, 13, 2022
|
|
7ELN
| Structure of Csy-AcrIF24-dsDNA | 分子名称: | 54-MER DNA, AcrIF24, CRISPR type I-F/YPEST-associated protein Csy2, ... | 著者 | Zhang, L, Feng, Y. | 登録日 | 2021-04-12 | 公開日 | 2022-04-20 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Insights into the inhibition of type I-F CRISPR-Cas system by a multifunctional anti-CRISPR protein AcrIF24. Nat Commun, 13, 2022
|
|
7BWR
| Mycobacterium smegmatis arabinosyltransferase complex EmbB2-AcpM2 in substrate DPA bound asymmetric "active state" | 分子名称: | CALCIUM ION, Integral membrane indolylacetylinositol arabinosyltransferase EmbB, Meromycolate extension acyl carrier protein, ... | 著者 | Gao, R.G, Zhang, L, Wang, Q, Rao, Z.H. | 登録日 | 2020-04-15 | 公開日 | 2020-05-27 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Cryo-EM snapshots of mycobacterial arabinosyltransferase complex EmbB2-AcpM2. Protein Cell, 11, 2020
|
|
7BX8
| Mycobacterium smegmatis arabinosyltransferase complex EmbB2-AcpM2 in symmetric "resting state" | 分子名称: | Integral membrane indolylacetylinositol arabinosyltransferase EmbB, Meromycolate extension acyl carrier protein | 著者 | Gao, R.G, Zhang, L, Wang, Q, Rao, Z.H. | 登録日 | 2020-04-17 | 公開日 | 2020-05-27 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Cryo-EM snapshots of mycobacterial arabinosyltransferase complex EmbB2-AcpM2. Protein Cell, 11, 2020
|
|
4O0U
| |
7V2S
| Crystal structure of juvenile hormone acid methyltransferase JHAMT isoform3 from silkworm | 分子名称: | Methyltranfer_dom domain-containing protein | 著者 | Guo, P.C, Zhang, Y.S, Zhang, l, Xu, H.Y. | 登録日 | 2021-08-09 | 公開日 | 2022-08-10 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.133 Å) | 主引用文献 | Structural characterization and functional analysis of juvenile hormone acid methyltransferase JHAMT3 from the silkworm, Bombyx mori. Insect Biochem.Mol.Biol., 151, 2022
|
|
7VEO
| Crystal structure of juvenile hormone acid methyltransferase silkworm JHAMT isoform3 complex with S-Adenosyl-L-homocysteine | 分子名称: | Methyltranfer_dom domain-containing protein, S-ADENOSYL-L-HOMOCYSTEINE | 著者 | Guo, P.C, Zhang, Y.S, Zhang, l, Xu, H.Y. | 登録日 | 2021-09-09 | 公開日 | 2022-09-28 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.53 Å) | 主引用文献 | Structural characterization and functional analysis of juvenile hormone acid methyltransferase JHAMT3 from the silkworm, Bombyx mori. Insect Biochem.Mol.Biol., 151, 2022
|
|
7VS3
| The crystal structure of rat calcium-dependent activator protein for secretion (CAPS) C2PH | 分子名称: | Calcium-dependent secretion activator 1, SULFATE ION | 著者 | Zhou, H, Wei, Z.Q, Zhang, L, Ren, Y.J, Ma, C. | 登録日 | 2021-10-25 | 公開日 | 2023-02-15 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.595 Å) | 主引用文献 | The C 2 and PH domains of CAPS constitute an effective PI(4,5)P2-binding unit essential for Ca 2+ -regulated exocytosis. Structure, 31, 2023
|
|
4O0S
| |
4O0W
| |
4BJ0
| Xyloglucan binding module (CBM4-2 X2-L110F) in complex with branched xyloses | 分子名称: | CALCIUM ION, XYLANASE, alpha-D-glucopyranose, ... | 著者 | Schantz, L, Hakansson, M, Logan, D.T, Nordberg-Karlsson, E, Ohlin, M. | 登録日 | 2013-04-15 | 公開日 | 2014-04-23 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1 Å) | 主引用文献 | Carbohydrate Binding Module Recognition of Xyloglucan Defined by Polar Contacts with Branching Xyloses and Ch-Pi Interactions. Proteins, 82, 2014
|
|
6BTJ
| |
7EQG
| Structure of Csy-AcrIF5 | 分子名称: | AcrIF5, CRISPR type I-F/YPEST-associated protein Csy2, CRISPR-associated protein Csy3, ... | 著者 | Zhang, L, Feng, Y. | 登録日 | 2021-05-01 | 公開日 | 2022-03-09 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | AcrIF5 specifically targets DNA-bound CRISPR-Cas surveillance complex for inhibition. Nat.Chem.Biol., 18, 2022
|
|