3EW8
 
 | | Crystal Structure Analysis of human HDAC8 D101L variant | | 分子名称: | 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide, BETA-MERCAPTOETHANOL, GLYCEROL, ... | | 著者 | Dowling, D.P, Gantt, S.L, Gattis, S.G, Fierke, C.A, Christianson, D.W. | | 登録日 | 2008-10-14 | | 公開日 | 2008-12-30 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural studies of human histone deacetylase 8 and its site-specific variants complexed with substrate and inhibitors.
Biochemistry, 47, 2008
|
|
3F0R
 | | Crystal Structure Analysis of Human HDAC8 complexed with trichostatin A in a new monoclinic crystal form | | 分子名称: | Histone deacetylase 8, POTASSIUM ION, TRICHOSTATIN A, ... | | 著者 | Dowling, D.P, Gantt, S.L, Gattis, S.G, Fierke, C.A, Christianson, D.W. | | 登録日 | 2008-10-25 | | 公開日 | 2008-12-30 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.54 Å) | | 主引用文献 | Structural studies of human histone deacetylase 8 and its site-specific variants complexed with substrate and inhibitors.
Biochemistry, 47, 2008
|
|
4CAA
 | | CLEAVED ANTICHYMOTRYPSIN T345R | | 分子名称: | ANTICHYMOTRYPSIN | | 著者 | Lukacs, C.M, Christianson, D.W. | | 登録日 | 1997-08-14 | | 公開日 | 1998-02-25 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Engineering an anion-binding cavity in antichymotrypsin modulates the "spring-loaded" serpin-protease interaction.
Biochemistry, 37, 1998
|
|
3F80
 | |
3ZNC
 | | MURINE CARBONIC ANHYDRASE IV COMPLEXED WITH BRINZOLAMIDE | | 分子名称: | (+)-4-ETHYLAMINO-3,4-DIHYDRO-2-(METHOXY)PROPYL-2H-THIENO[3,2-E]-1,2-THIAZINE-6-SULFONAMIDE-1,1-DIOXIDE, CARBONIC ANHYDRASE IV, ZINC ION | | 著者 | Stams, T, Chen, Y, Christianson, D.W. | | 登録日 | 1998-02-10 | | 公開日 | 1999-03-23 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structures of murine carbonic anhydrase IV and human carbonic anhydrase II complexed with brinzolamide: molecular basis of isozyme-drug discrimination.
Protein Sci., 7, 1998
|
|
3KBK
 | | Epi-isozizaene synthase complexed with Hg | | 分子名称: | CHLORIDE ION, Epi-isozizaene synthase, MERCURY (II) ION, ... | | 著者 | Aaron, J.A, Lin, X, Cane, D.E, Christianson, D.W. | | 登録日 | 2009-10-20 | | 公開日 | 2010-02-09 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure of Epi-Isozizaene Synthase from Streptomyces coelicolor A3(2), a Platform for New Terpenoid Cyclization Templates
Biochemistry, 49, 2010
|
|
3KB9
 | | Epi-isozizaene synthase: Complex with Mg, inorganic pyrophosphate and benzyl triethyl ammonium cation | | 分子名称: | Epi-isozizaene synthase, GLYCEROL, MAGNESIUM ION, ... | | 著者 | Aaron, J.A, Lin, X, Cane, D.E, Christianson, D.W. | | 登録日 | 2009-10-20 | | 公開日 | 2010-02-09 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.598 Å) | | 主引用文献 | Structure of Epi-Isozizaene Synthase from Streptomyces coelicolor A3(2), a Platform for New Terpenoid Cyclization Templates
Biochemistry, 49, 2010
|
|
5DW7
 | | Crystal structure of the unliganded geosmin synthase N-terminal domain from Streptomyces coelicolor | | 分子名称: | Germacradienol/geosmin synthase | | 著者 | Lombardi, P.M, Harris, G.G, Pemberton, T.A, Matsui, T, Weiss, T.M, Cole, K.E, Koksal, M, Murphy, F.V, Vedula, L.S, Chou, W.K, Cane, D.E, Christianson, D.W. | | 登録日 | 2015-09-22 | | 公開日 | 2015-11-25 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.202 Å) | | 主引用文献 | Structural Studies of Geosmin Synthase, a Bifunctional Sesquiterpene Synthase with alpha alpha Domain Architecture That Catalyzes a Unique Cyclization-Fragmentation Reaction Sequence.
Biochemistry, 54, 2015
|
|
2PS5
 | | N225D Trichodiene Synthase: Complex With Mg and Pyrophosphate | | 分子名称: | 1,2-ETHANEDIOL, MAGNESIUM ION, PYROPHOSPHATE 2-, ... | | 著者 | Vedula, L.S, Cane, D.E, Christianson, D.W. | | 登録日 | 2007-05-04 | | 公開日 | 2007-12-18 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural and mechanistic analysis of trichodiene synthase using site-directed mutagenesis: probing the catalytic function of tyrosine-295 and the asparagine-225/serine-229/glutamate-233-Mg2+B motif.
Arch.Biochem.Biophys., 469, 2008
|
|
2PS4
 | | N225D trichodiene synthase | | 分子名称: | 1,2-ETHANEDIOL, MAGNESIUM ION, Trichodiene synthase | | 著者 | Vedula, L.S, Cane, D.E, Christianson, D.W. | | 登録日 | 2007-05-04 | | 公開日 | 2007-12-18 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.46 Å) | | 主引用文献 | Structural and mechanistic analysis of trichodiene synthase using site-directed mutagenesis: probing the catalytic function of tyrosine-295 and the asparagine-225/serine-229/glutamate-233-Mg2+B motif.
Arch.Biochem.Biophys., 469, 2008
|
|
5EDU
 | |
2PHA
 | |
2PLL
 | | Crystal structure of perdeuterated human arginase I | | 分子名称: | 2(S)-AMINO-6-BORONOHEXANOIC ACID, MANGANESE (II) ION, arginase-1 | | 著者 | Di Costanzo, L, Moulin, M, Haertlein, M, Meilleur, F, Christianson, D.W. | | 登録日 | 2007-04-19 | | 公開日 | 2007-08-14 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Expression, purification, assay, and crystal structure of perdeuterated human arginase I
Arch.Biochem.Biophys., 465, 2007
|
|
5DZ2
 | | Geosmin synthase from Streptomyces coelicolor N-terminal domain complexed with three Mg2+ ions and alendronic acid | | 分子名称: | ALENDRONATE, Germacradienol/geosmin synthase, MAGNESIUM ION | | 著者 | Harris, G.G, Lombardi, P.M, Pemberton, T.A, Matsui, T, Weiss, T.M, Cole, K.E, Koksal, M, Murphy, F.V, Vedula, L.S, Chou, W.K.W, Cane, D.E, Christianson, D.W. | | 登録日 | 2015-09-25 | | 公開日 | 2015-12-09 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.111 Å) | | 主引用文献 | Structural Studies of Geosmin Synthase, a Bifunctional Sesquiterpene Synthase with alpha alpha Domain Architecture That Catalyzes a Unique Cyclization-Fragmentation Reaction Sequence.
Biochemistry, 54, 2015
|
|
5ERN
 | |
2PHO
 | |
5EFB
 | |
5ERM
 | |
3LG5
 | | F198A Epi-isozizaene synthase: Complex with Mg, inorganic pyrophosphate and benzyl triethyl ammonium cation | | 分子名称: | Epi-isozizaene synthase, MAGNESIUM ION, N-benzyl-N,N-diethylethanaminium, ... | | 著者 | Aaron, J.A, Lin, X, Cane, D.E, Christianson, D.W. | | 登録日 | 2010-01-19 | | 公開日 | 2010-02-09 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.641 Å) | | 主引用文献 | Structure of Epi-Isozizaene Synthase from Streptomyces coelicolor A3(2), a Platform for New Terpenoid Cyclization Templates
Biochemistry, 49, 2010
|
|
3LP4
 | |
3MFV
 | |
2Q9Z
 | | Trichodiene synthase: Complex with inorganic pyrophosphate resulting from the reaction with 2-fluorofarnesyl diphosphate | | 分子名称: | 1,2-ETHANEDIOL, MAGNESIUM ION, PYROPHOSPHATE 2-, ... | | 著者 | Vedula, L.S, Zhao, Y, Coates, R.M, Koyama, T, Cane, D.E, Christianson, D.W. | | 登録日 | 2007-06-14 | | 公開日 | 2007-10-30 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Exploring biosynthetic diversity with trichodiene synthase.
Arch.Biochem.Biophys., 466, 2007
|
|
3MJL
 | |
2OA6
 | | Aristolochene synthase from Aspergillus terreus complexed with pyrophosphate | | 分子名称: | Aristolochene synthase, BETA-MERCAPTOETHANOL, GLYCEROL, ... | | 著者 | Shishova, E.Y, Di Costanzo, L, Cane, D.E, Christianson, D.W. | | 登録日 | 2006-12-15 | | 公開日 | 2007-01-30 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | X-ray crystal structure of aristolochene synthase from Aspergillus terreus and evolution of templates for the cyclization of farnesyl diphosphate
Biochemistry, 46, 2007
|
|
5EEK
 | |
