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3MJ9
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BU of 3mj9 by Molmil
Crystal structure of JAML in complex with the stimulatory antibody HL4E10
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Junctional adhesion molecule-like, STIMULATORY HAMSTER ANTIBODY HL4E10 FAB HEAVY CHAIN, ...
著者Verdino, P, Wilson, I.A.
登録日2010-04-12
公開日2011-02-23
最終更新日2024-11-27
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Molecular insights into gamma delta T cell costimulation by an anti-JAML antibody.
Structure, 19, 2011
3FO0
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BU of 3fo0 by Molmil
Crystal structure of hapten complex of catalytic elimination antibody 13G5 (wild-type)
分子名称: 5-[(2-AMINO-1H-BENZIMIDAZOL-6-YL)AMINO]-5-OXOPENTANOIC ACID, Catalytic antibody Fab 13G5 IgG2b heavy chain chimera, Catalytic antibody Fab 13G5 kappa light chain chimera, ...
著者Debler, E.W, Wilson, I.A.
登録日2008-12-27
公開日2009-11-10
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献An aspartate and a water molecule mediate efficient acid-base catalysis in a tailored antibody pocket.
Proc.Natl.Acad.Sci.USA, 106, 2009
3LZG
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BU of 3lzg by Molmil
Crystal structure of a 2009 H1N1 influenza virus hemagglutinin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
著者Xu, R, Wilson, I.A.
登録日2010-03-01
公開日2010-04-14
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis of preexisting immunity to the 2009 H1N1 pandemic influenza virus.
Science, 328, 2010
3FN0
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BU of 3fn0 by Molmil
Crystal structure of HIV-1 neutralizing human Fab Z13e1 in complex with a 12-residue peptide containing the Z13e1 epitope on gp41
分子名称: Envelope polyprotein gp160, Fab Z13e1
著者Pejchal, R, Wilson, I.A, Zwick, M.B.
登録日2008-12-22
公開日2009-06-23
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A conformational switch in human immunodeficiency virus gp41 revealed by the structures of overlapping epitopes recognized by neutralizing antibodies.
J.Virol., 83, 2009
3FO9
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BU of 3fo9 by Molmil
Crystal structure of aldolase antibody 33F12 Fab' in complex with hapten 1,3-diketone
分子名称: 5-{[4-(5-methyl-3-oxohex-4-en-1-yl)phenyl]amino}-5-oxopentanoic acid, Immunoglobulin IGG2A - heavy chain, Immunoglobulin IGG2A - light chain
著者Zhu, X, Wilson, I.A.
登録日2008-12-29
公開日2009-12-22
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Direct observation of an enamine intermediate in amine catalysis
J.Am.Chem.Soc., 131, 2009
3MUG
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BU of 3mug by Molmil
Crystal structure of human Fab PG16, a broadly reactive and potent HIV-1 neutralizing antibody
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody PG16 Heavy Chain, ...
著者Pejchal, R, Walker, L.M, Burton, D.R, Wilson, I.A.
登録日2010-05-03
公開日2010-06-16
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Structure and function of broadly reactive antibody PG16 reveal an H3 subdomain that mediates potent neutralization of HIV-1.
Proc.Natl.Acad.Sci.USA, 107, 2010
3MTX
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BU of 3mtx by Molmil
Crystal structure of chicken MD-1
分子名称: (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, GLYCEROL, Protein MD-1, ...
著者Yoon, S.I, Hong, M, Han, G.W, Wilson, I.A.
登録日2010-05-01
公開日2010-06-09
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of soluble MD-1 and its interaction with lipid IVa.
Proc.Natl.Acad.Sci.USA, 107, 2010
3MUH
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BU of 3muh by Molmil
Crystal structure of PG9 light chain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody PG9 light chain
著者Pejchal, R, Walker, L.M, Burton, D.R, Wilson, I.A.
登録日2010-05-03
公開日2010-06-16
最終更新日2024-11-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure and function of broadly reactive antibody PG16 reveal an H3 subdomain that mediates potent neutralization of HIV-1.
Proc.Natl.Acad.Sci.USA, 107, 2010
3MU3
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BU of 3mu3 by Molmil
Crystal structure of chicken MD-1 complexed with lipid IVa
分子名称: (R)-((2R,3S,4R,5R,6R)-3-HYDROXY-2-(HYDROXYMETHYL)-5-((R)-3-HYDROXYTETRADECANAMIDO)-6-(PHOSPHONOOXY)TETRAHYDRO-2H-PYRAN-4-YL) 3-HYDROXYTETRADECANOATE, 2-deoxy-3-O-[(3R)-3-hydroxytetradecanoyl]-2-{[(3R)-3-hydroxytetradecanoyl]amino}-4-O-phosphono-beta-D-glucopyranose, GLYCEROL, ...
著者Yoon, S.I, Hong, M, Han, G.W, Wilson, I.A.
登録日2010-05-01
公開日2010-06-09
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of soluble MD-1 and its interaction with lipid IVa.
Proc.Natl.Acad.Sci.USA, 107, 2010
3CFJ
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BU of 3cfj by Molmil
Crystal structure of catalytic elimination antibody 34E4, orthorhombic crystal form
分子名称: CATALYTIC ANTIBODY FAB 34E4 HEAVY CHAIN fusion, CATALYTIC ANTIBODY FAB 34E4 LIGHT CHAIN fusion, GLYCEROL, ...
著者Debler, E.W, Wilson, I.A.
登録日2008-03-04
公開日2008-04-15
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Conformational isomerism can limit antibody catalysis.
J.Biol.Chem., 283, 2008
3CFE
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BU of 3cfe by Molmil
Crystal structure of purple-fluorescent antibody EP2-25C10
分子名称: GLYCEROL, PURPLE-FLUORESCENT ANTIBODY EP2-25C10-IGG2B HEAVY CHAIN, PURPLE-FLUORESCENT ANTIBODY EP2-25C10-KAPPA LIGHT CHAIN, ...
著者Debler, E.W, Heine, A, Wilson, I.A.
登録日2008-03-03
公開日2008-03-18
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.99 Å)
主引用文献Deeply inverted electron-hole recombination in a luminescent antibody-stilbene complex.
Science, 319, 2008
3C2A
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BU of 3c2a by Molmil
Antibody Fab fragment 447-52D in complex with UG1033 peptide
分子名称: Envelope glycoprotein, Fab 447-52D heavy chain, Fab 447-52D light chain
著者Dhillon, A.K, Stanfield, R.L, Wilson, I.A.
登録日2008-01-24
公開日2008-07-08
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure determination of an anti-HIV-1 Fab 447-52D-peptide complex from an epitaxially twinned data set
Acta Crystallogr.,Sect.D, 64, 2008
3CFK
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BU of 3cfk by Molmil
Crystal structure of catalytic elimination antibody 34E4, triclinic crystal form
分子名称: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CADMIUM ION, CATALYTIC ANTIBODY FAB 34E4 HEAVY CHAIN,Uncharacterized protein, ...
著者Debler, E.W, Wilson, I.A.
登録日2008-03-04
公開日2008-04-15
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Conformational isomerism can limit antibody catalysis.
J.Biol.Chem., 283, 2008
3CN3
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BU of 3cn3 by Molmil
Human transthyretin (TTR) in complex with 1,3-Dibromo-2-hydroxy-5-phenoxybenzene
分子名称: 2,6-dibromo-4-phenoxyphenol, Transthyretin
著者Connelly, S, Wilson, I.A.
登録日2008-03-24
公開日2008-10-28
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Toward optimization of the linker substructure common to transthyretin amyloidogenesis inhibitors using biochemical and structural studies.
J.Med.Chem., 51, 2008
3CN4
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BU of 3cn4 by Molmil
Human transthyretin (TTR) in complex with N-(3,5-Dibromo-4-hydroxyphenyl)benzamide
分子名称: N-(3,5-dibromo-4-hydroxyphenyl)benzamide, Transthyretin
著者Connelly, S, Wilson, I.A.
登録日2008-03-24
公開日2008-10-28
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Toward optimization of the linker substructure common to transthyretin amyloidogenesis inhibitors using biochemical and structural studies.
J.Med.Chem., 51, 2008
3CUP
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BU of 3cup by Molmil
Crystal structure of the MHC class II molecule I-Ag7 in complex with the peptide GAD221-235
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, H-2 class II histocompatibility antigen, ...
著者Corper, A.L, Yoshida, K, Teyton, L, Wilson, I.A.
登録日2008-04-16
公開日2009-04-21
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (3.09 Å)
主引用文献Crystal structure of the MHC class II molecule I-Ag7 in complex with the peptide GAD221-235
To be Published
3CFD
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BU of 3cfd by Molmil
Purple-fluorescent antibody EP2-25C10 in complex with its stilbene hapten
分子名称: 4-(4-STYRYL-PHENYLCARBAMOYL)-BUTYRIC ACID, GLYCEROL, PURPLE-FLUORESCENT ANTIBODY EP2-25C10-IGG2B HEAVY CHAIN, ...
著者Debler, E.W, Heine, A, Wilson, I.A.
登録日2008-03-03
公開日2008-03-18
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Deeply inverted electron-hole recombination in a luminescent antibody-stilbene complex.
Science, 319, 2008
3CN2
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BU of 3cn2 by Molmil
Human transthyretin (TTR) in complex with 3,5-Dibromo-4-hydroxybiphenyl
分子名称: 3,5-dibromobiphenyl-4-ol, Transthyretin
著者Connelly, S, Wilson, I.A.
登録日2008-03-24
公開日2008-10-28
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.52 Å)
主引用文献Toward optimization of the linker substructure common to transthyretin amyloidogenesis inhibitors using biochemical and structural studies.
J.Med.Chem., 51, 2008
3CFC
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BU of 3cfc by Molmil
High-resolution structure of blue fluorescent antibody EP2-19G2
分子名称: BLUE FLUORESCENT ANTIBODY EP2-19G2-IGG2B HEAVY CHAIN, BLUE FLUORESCENT ANTIBODY EP2-19G2-KAPPA LIGHT CHAIN, GLYCEROL
著者Debler, E.W, Wilson, I.A.
登録日2008-03-03
公開日2008-03-18
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Deeply inverted electron-hole recombination in a luminescent antibody-stilbene complex.
Science, 319, 2008
2OQJ
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BU of 2oqj by Molmil
Crystal structure analysis of Fab 2G12 in complex with peptide 2G12.1
分子名称: Fab 2G12 heavy chain, Fab 2G12 light chain, peptide 2G12.1 (ACPPSHVLDMRSGTCLAAEGK)
著者Calarese, D.A, Stanfield, R.L, Menendez, A, Scott, J.K, Wilson, I.A.
登録日2007-01-31
公開日2008-01-15
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A peptide inhibitor of HIV-1 neutralizing antibody 2G12 is not a structural mimic of the natural carbohydrate epitope on gp120.
Faseb J., 22, 2008
6PBW
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BU of 6pbw by Molmil
Crystal structure of Fab667 complex
分子名称: Fab667 heavy chain, Fab667 light chain, GLYCEROL, ...
著者Oyen, D, Wilson, I.A.
登録日2019-06-14
公開日2020-03-04
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.058 Å)
主引用文献Structure and mechanism of monoclonal antibody binding to the junctional epitope of Plasmodium falciparum circumsporozoite protein.
Plos Pathog., 16, 2020
2PRT
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BU of 2prt by Molmil
Structure of the Wilms Tumor Suppressor Protein Zinc Finger Domain Bound to DNA
分子名称: DNA (5'-D(*CP*AP*GP*AP*CP*GP*CP*CP*CP*CP*CP*GP*CP*G)-3'), DNA (5'-D(*CP*GP*CP*GP*GP*GP*GP*GP*CP*GP*TP*CP*TP*G)-3'), Wilms tumor 1, ...
著者Stoll, R, Lee, B.M, Debler, E.W, Laity, J.H, Wilson, I.A, Dyson, H.J, Wright, P.E.
登録日2007-05-04
公開日2008-03-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Structure of the Wilms tumor suppressor protein zinc finger domain bound to DNA
J.Mol.Biol., 372, 2007
6PBV
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BU of 6pbv by Molmil
Crystal structure of Fab668 complex
分子名称: 1,2-ETHANEDIOL, Fab668 heavy chain, Fab668 light chain, ...
著者Oyen, D, Wilson, I.A.
登録日2019-06-14
公開日2020-03-04
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.566 Å)
主引用文献Structure and mechanism of monoclonal antibody binding to the junctional epitope of Plasmodium falciparum circumsporozoite protein.
Plos Pathog., 16, 2020
6PZD
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BU of 6pzd by Molmil
Crystal structure of the neuraminidase stabilization mutant Y169aH from A/Shanghai/2/2013 (H7N9)
分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Zhu, X, Wilson, I.A.
登録日2019-07-31
公開日2019-12-04
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.12 Å)
主引用文献Structural Basis of Protection against H7N9 Influenza Virus by Human Anti-N9 Neuraminidase Antibodies.
Cell Host Microbe, 26, 2019
6Q1Z
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BU of 6q1z by Molmil
Crystal structure of human 1G04 Fab in complex with influenza virus neuraminidase from A/Hunan/02650/2016 (H7N9)
分子名称: 1G04 Fab IgG1 heavy chain, 1G04 Fab kappa light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Zhu, X, Wilson, I.A.
登録日2019-08-06
公開日2019-10-23
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (3.446 Å)
主引用文献Broadly protective human antibodies that target the active site of influenza virus neuraminidase.
Science, 366, 2019

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