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1XUG
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BU of 1xug by Molmil
TRYPSIN-BABIM-ZN+2, PH 8.2
分子名称: BIS(5-AMIDINO-BENZIMIDAZOLYL)METHANE, CALCIUM ION, TRYPSIN, ...
著者Katz, B.A, Clark, J.M, Finer-Moore, J.S, Jenkins, T.E, Johnson, C.R, Rose, M.J, Luong, C, Moore, W.R, Stroud, R.M.
登録日1997-10-10
公開日1998-12-16
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Design of potent selective zinc-mediated serine protease inhibitors.
Nature, 391, 1998
1Y4C
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Designed Helical Protein fusion MBP
分子名称: Maltose binding protein fused with designed helical protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者LaPorte, S.L, Forsyth, C.M, Cunningham, B.C, Miercke, L.J, Akhavan, D, Stroud, R.M.
登録日2004-11-30
公開日2005-02-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献De novo design of an IL-4 antagonist and its structure at 1.9 A.
Proc.Natl.Acad.Sci.Usa, 102, 2005
1XUJ
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BU of 1xuj by Molmil
TRYPSIN-KETO-BABIM-ZN+2, PH 8.2
分子名称: BIS(5-AMIDINO-BENZIMIDAZOLYL)METHANONE ZINC, CALCIUM ION, SULFATE ION, ...
著者Katz, B.A, Clark, J.M, Finer-Moore, J.S, Jenkins, T.E, Johnson, C.R, Rose, M.J, Luong, C, Moore, W.R, Stroud, R.M.
登録日1997-10-10
公開日1998-11-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Design of potent selective zinc-mediated serine protease inhibitors.
Nature, 391, 1998
1XUK
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BU of 1xuk by Molmil
TRYPSIN-BABIM-SULFATE, PH 5.9
分子名称: BIS(5-AMIDINO-BENZIMIDAZOLYL)METHANE, CALCIUM ION, SULFATE ION, ...
著者Katz, B.A, Clark, J.M, Finer-Moore, J.S, Jenkins, T.E, Johnson, C.R, Rose, M.J, Luong, C, Moore, W.R, Stroud, R.M.
登録日1997-10-10
公開日1998-11-11
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Design of potent selective zinc-mediated serine protease inhibitors.
Nature, 391, 1998
1YTG
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BU of 1ytg by Molmil
SIV PROTEASE CRYSTALLIZED WITH PEPTIDE PRODUCT
分子名称: HIV PROTEASE, PEPTIDE PRODUCT
著者Rose, R.B, Craik, C.S, Douglas, N.L, Stroud, R.M.
登録日1996-08-01
公開日1997-03-12
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Three-dimensional structures of HIV-1 and SIV protease product complexes.
Biochemistry, 35, 1996
1YTJ
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BU of 1ytj by Molmil
SIV PROTEASE CRYSTALLIZED WITH PEPTIDE PRODUCT
分子名称: PEPTIDE PRODUCT, SIV PROTEASE
著者Rose, R.B, Craik, C.S, Douglas, N.L, Stroud, R.M.
登録日1996-08-01
公開日1997-03-12
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Three-dimensional structures of HIV-1 and SIV protease product complexes.
Biochemistry, 35, 1996
1YTH
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BU of 1yth by Molmil
SIV PROTEASE CRYSTALLIZED WITH PEPTIDE PRODUCT
分子名称: HIV PROTEASE, PEPTIDE PRODUCT
著者Rose, R.B, Craik, C.S, Douglas, N.L, Stroud, R.M.
登録日1996-08-01
公開日1997-03-12
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Three-dimensional structures of HIV-1 and SIV protease product complexes.
Biochemistry, 35, 1996
1YTI
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BU of 1yti by Molmil
SIV PROTEASE CRYSTALLIZED WITH PEPTIDE PRODUCT
分子名称: PEPTIDE PRODUCT, SIV PROTEASE
著者Rose, R.B, Craik, C.S, Douglas, N.L, Stroud, R.M.
登録日1996-08-01
公開日1997-03-12
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Three-dimensional structures of HIV-1 and SIV protease product complexes.
Biochemistry, 35, 1996
2A9W
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BU of 2a9w by Molmil
E. coli TS complexed with dUMP and inhibitor GA9
分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 2-BROMOPHENOL, 3,3-BIS(3-BROMO-4-HYDROXYPHENYL)-7-CHLORO-1H,3H-BENZO[DE]ISOCHROMEN-1-ONE, ...
著者Finer-Moore, J.S, Anderson, A.C, O'Neil, R.H, Costi, M.P, Ferrari, S, Krucinski, J, Stroud, R.M.
登録日2005-07-12
公開日2005-10-11
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献The structure of Cryptococcus neoformans thymidylate synthase suggests strategies for using target dynamics for species-specific inhibition.
Acta Crystallogr.,Sect.D, 61, 2005
1SQG
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BU of 1sqg by Molmil
The crystal structure of the E. coli Fmu apoenzyme at 1.65 A resolution
分子名称: SUN protein
著者Foster, P.G, Nunes, C.R, Greene, P, Moustakas, D, Stroud, R.M.
登録日2004-03-18
公開日2004-05-18
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献The First Structure of an RNA m5C Methyltransferase, Fmu, Provides Insight into Catalytic Mechanism and Specific Binding of RNA Substrate
Structure, 11, 2003
1R2J
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BU of 1r2j by Molmil
FkbI for Biosynthesis of Methoxymalonyl Extender Unit of Fk520 Polyketide Immunosuppresant
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, protein FkbI
著者Watanabe, K, Khosla, C, Stroud, R.M, Tsai, S.-C.
登録日2003-09-28
公開日2003-11-25
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structure of an Acyl-ACP Dehydrogenase from the FK520 Polyketide Biosynthetic Pathway: Insights into Extender Unit Biosynthesis
J.Mol.Biol., 334, 2003
1QZF
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BU of 1qzf by Molmil
Crystal structure of DHFR-TS from Cryptosporidium hominis
分子名称: 10-PROPARGYL-5,8-DIDEAZAFOLIC ACID, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, FOLIC ACID, ...
著者O'Neil, R.H, Lilien, R.H, Donald, B.R, Stroud, R.M, Anderson, A.C.
登録日2003-09-16
公開日2003-11-11
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Phylogenetic classification of protozoa based on the structure of the linker domain in the bifunctional enzyme, dihydrofolate reductase-thymidylate synthase
J.Biol.Chem., 278, 2003
1U7C
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BU of 1u7c by Molmil
Crystal Structure of AmtB from E.Coli with Methyl Ammonium.
分子名称: METHYLAMINE, Probable ammonium transporter
著者Khademi, S, O'Connell III, J, Remis, J, Robles-Colmenares, Y, Miercke, L.J.W, Stroud, R.M.
登録日2004-08-03
公開日2004-09-21
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Mechanism of ammonia transport by Amt/MEP/Rh: structure of AmtB at 1.35 A
Science, 305, 2004
1RJ9
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BU of 1rj9 by Molmil
Structure of the heterodimer of the conserved GTPase domains of the Signal Recognition Particle (Ffh) and Its Receptor (FtsY)
分子名称: MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, Signal Recognition Protein, ...
著者Egea, P.F, Shan, S.O, Napetschnig, J, Savage, D.F, Walter, P, Stroud, R.M.
登録日2003-11-18
公開日2004-01-27
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Substrate twinning activates the signal recognition particle and its receptor
Nature, 427, 2004
1U77
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BU of 1u77 by Molmil
Crystal Structure of Ammonia Channel AmtB from E. Coli
分子名称: Probable ammonium transporter
著者Khademi, S, O'Connell III, J, Remis, J, Robles-Colmenares, Y, Miercke, L.J.W, Stroud, R.M.
登録日2004-08-02
公開日2004-09-21
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Mechanism of ammonia transport by Amt/MEP/Rh: structure of AmtB at 1.35 A
Science, 305, 2004
1U7G
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Crystal Structure of Ammonia Channel AmtB from E. Coli
分子名称: AMMONIA, AMMONIUM ION, Probable ammonium transporter, ...
著者Khademi, S, O'Connell III, J, Remis, J, Robles-Colmenares, Y, Miercke, L.J.W, Stroud, R.M.
登録日2004-08-03
公開日2004-09-21
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Mechanism of ammonia transport by Amt/MEP/Rh: structure of AmtB at 1.35 A
Science, 305, 2004
1R3E
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BU of 1r3e by Molmil
Crystal Structure of tRNA Pseudouridine Synthase TruB and Its RNA Complex: RNA-protein Recognition Through a Combination of Rigid Docking and Induced Fit
分子名称: 5'-R(*CP*UP*GP*UP*GP*UP*(FHU)P*CP*GP*AP*UP*CP*CP*AP*CP*AP*G)-3', 5'-R(*CP*UP*GP*UP*GP*UP*UP*CP*GP*AP*UP*CP*CP*AP*CP*AP*G)-3', tRNA pseudouridine synthase B
著者Pan, H, Agarwalla, S, Moustakas, D.T, Finer-Moore, J, Stroud, R.M.
登録日2003-10-01
公開日2003-11-04
最終更新日2018-02-07
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structure of tRNA Pseudouridine Synthase TruB and Its RNA Complex: RNA Recognition Through a Combination of Rigid Docking and Induced Fit
Proc.Natl.Acad.Sci.USA, 100, 2003
1RC2
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BU of 1rc2 by Molmil
2.5 Angstrom Resolution X-ray Structure of Aquaporin Z
分子名称: 2-O-octyl-beta-D-glucopyranose, Aquaporin Z
著者Savage, D.F, Egea, P.F, Robles, Y.C, O'Connell III, J.D, Stroud, R.M.
登録日2003-11-03
公開日2003-11-25
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Architecture and selectivity in aquaporins: 2.5 a X-ray structure of aquaporin Z
Plos Biol., 1, 2003
1R3F
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BU of 1r3f by Molmil
Crystal Structure of tRNA Pseudouridine Synthase TruB and Its RNA Complex: RNA-protein Recognition Through a Combination of Rigid Docking and Induced Fit
分子名称: tRNA pseudouridine synthase B
著者Pan, H, Agarwalla, S, Moustakas, D.T, Finer-Moore, J, Stroud, R.M.
登録日2003-10-01
公開日2003-11-04
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structure of tRNA Pseudouridine Synthase TruB and Its RNA Complex: RNA Recognition Through a Combination of Rigid Docking and Induced Fit
Proc.Natl.Acad.Sci.USA, 100, 2003
1TSL
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BU of 1tsl by Molmil
L. CASEI THYMIDYLATE SYNTHASE WITH SPECIES SPECIFIC INHIBITOR
分子名称: 3'-3"-DICHLOROPHENOL-1,8-3H-BENZO[DE]ISOCHROMEN-1-ONE, PHOSPHATE ION, THYMIDYLATE SYNTHASE
著者Stout, T.J, Stroud, R.M.
登録日1997-06-12
公開日1998-06-17
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure-based design of inhibitors specific for bacterial thymidylate synthase.
Biochemistry, 38, 1999
1TSM
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BU of 1tsm by Molmil
L. CASEI THYMIDYLATE SYNTHASE WITH SPECIES SPECIFIC INHIBITOR
分子名称: 3-DIPHENOL-6-NITRO-3H-BENZO[DE]ISOCHROMEN-1-ONE, PHOSPHATE ION, THYMIDYLATE SYNTHASE
著者Stout, T.J, Stroud, R.M.
登録日1997-06-12
公開日1998-06-17
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure-based design of inhibitors specific for bacterial thymidylate synthase.
Biochemistry, 38, 1999
1TQY
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BU of 1tqy by Molmil
The Actinorhodin Ketosynthase/Chain Length Factor
分子名称: ACETYL GROUP, Actinorhodin polyketide putative beta-ketoacyl synthase 1, Actinorhodin polyketide putative beta-ketoacyl synthase 2, ...
著者Keatinge-Clay, A.T, Maltby, D.A, Medzihradszky, K.F, Khosla, C, Stroud, R.M.
登録日2004-06-18
公開日2004-07-27
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献An antibiotic factory caught in action.
Nat.Struct.Mol.Biol., 11, 2004
1SQF
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BU of 1sqf by Molmil
The crystal structure of E. coli Fmu binary complex with S-Adenosylmethionine at 2.1 A resolution
分子名称: S-ADENOSYLMETHIONINE, SUN protein
著者Foster, P.G, Nunes, C.R, Greene, P, Moustakas, D, Stroud, R.M.
登録日2004-03-18
公開日2004-05-18
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The First Structure of an RNA m5C Methyltransferase, Fmu, Provides Insight into Catalytic Mechanism and Specific Binding of RNA Substrate
Structure, 11, 2003
1TJS
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BU of 1tjs by Molmil
E. COLI THYMIDYLATE SYNTHASE
分子名称: PHOSPHATE ION, THYMIDYLATE SYNTHASE
著者Stout, T.J, Sage, C.R, Stroud, R.M.
登録日1997-06-27
公開日1998-07-01
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The additivity of substrate fragments in enzyme-ligand binding.
Structure, 6, 1998
1TDU
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BU of 1tdu by Molmil
E. COLI THYMIDYLATE SYNTHASE IN COMPLEX WITH CB3717 AND 2'-DEOXYURIDINE (DURD)
分子名称: 10-PROPARGYL-5,8-DIDEAZAFOLIC ACID, 2'-DEOXYURIDINE, PHOSPHATE ION, ...
著者Stout, T.J, Sage, C.R, Stroud, R.M.
登録日1997-06-25
公開日1998-07-01
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The additivity of substrate fragments in enzyme-ligand binding.
Structure, 6, 1998

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