1R2J

FkbI for Biosynthesis of Methoxymalonyl Extender Unit of Fk520 Polyketide Immunosuppresant

Summary for 1R2J

Entry DOI	10.2210/pdb1r2j/pdb
Descriptor	protein FkbI, FLAVIN-ADENINE DINUCLEOTIDE (3 entities in total)
Functional Keywords	fk520; fk506; polyketide synthase; polyketide; acyl-coa dehydrogenase; crystal structure; aldehyde dehydrogenase, oxidoreductase
Biological source	Streptomyces hygroscopicus
Total number of polymer chains	1
Total formula weight	39017.88
Authors	Watanabe, K.,Khosla, C.,Stroud, R.M.,Tsai, S.-C. (deposition date: 2003-09-28, release date: 2003-11-25, Last modification date: 2024-02-14)
Primary citation	Watanabe, K.,Khosla, C.,Stroud, R.M.,Tsai, S.-C. Crystal Structure of an Acyl-ACP Dehydrogenase from the FK520 Polyketide Biosynthetic Pathway: Insights into Extender Unit Biosynthesis J.Mol.Biol., 334:435-444, 2003 Cited by PubMed: 14623185 DOI: 10.1016/j.jmb.2003.10.021 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation