3MO2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3mo2 by Molmil](/molmil-images/mine/3mo2) | human G9a-like (GLP, also known as EHMT1) in complex with inhibitor E67 | 分子名称: | 7-[(5-aminopentyl)oxy]-N~4~-(1-benzylpiperidin-4-yl)-N~2~-[3-(dimethylamino)propyl]-6-methoxyquinazoline-2,4-diamine, Histone-lysine N-methyltransferase, H3 lysine-9 specific 5, ... | 著者 | Chang, Y, Horton, J.R, Cheng, X. | 登録日 | 2010-04-22 | 公開日 | 2010-06-30 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | 主引用文献 | Adding a lysine mimic in the design of potent inhibitors of histone lysine methyltransferases. J.Mol.Biol., 400, 2010
|
|
3MO5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3mo5 by Molmil](/molmil-images/mine/3mo5) | Human G9a-like (GLP, also known as EHMT1) in complex with inhibitor E72 | 分子名称: | 7-[(5-aminopentyl)oxy]-N~4~-[1-(5-aminopentyl)piperidin-4-yl]-N~2~-[3-(dimethylamino)propyl]-6-methoxyquinazoline-2,4-diamine, Histone-lysine N-methyltransferase, H3 lysine-9 specific 5, ... | 著者 | Chang, Y, Horton, J.R, Cheng, X. | 登録日 | 2010-04-22 | 公開日 | 2010-06-30 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | Adding a lysine mimic in the design of potent inhibitors of histone lysine methyltransferases. J.Mol.Biol., 400, 2010
|
|
1BQK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1bqk by Molmil](/molmil-images/mine/1bqk) | OXIDIZED PSEUDOAZURIN | 分子名称: | COPPER (II) ION, PSEUDOAZURIN | 著者 | Inoue, T, Nishio, N, Hamanaka, S, Shimomura, T, Harada, S, Suzuki, S, Kohzuma, T, Shidara, S, Iwasaki, H, Kai, Y. | 登録日 | 1998-08-17 | 公開日 | 1999-08-17 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Crystal structure determinations of oxidized and reduced pseudoazurins from Achromobacter cycloclastes. Concerted movement of copper site in redox forms with the rearrangement of hydrogen bond at a remote histidine. J.Biol.Chem., 274, 1999
|
|
1N27
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1n27 by Molmil](/molmil-images/mine/1n27) | Solution structure of the PWWP domain of mouse Hepatoma-derived growth factor, related protein 3 | 分子名称: | Hepatoma-derived growth factor, related protein 3 | 著者 | Nameki, N, Kigawa, T, Koshiba, S, Kobayashi, N, Tochio, N, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2002-10-22 | 公開日 | 2003-12-23 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the PWWP domain of the hepatoma-derived growth factor family. Protein Sci., 14, 2005
|
|
2ROZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2roz by Molmil](/molmil-images/mine/2roz) | Structure of the C-terminal PID Domain of Fe65L1 Complexed with the Cytoplasmic Tail of APP Reveals a Novel Peptide Binding Mode | 分子名称: | Amyloid beta A4 precursor protein-binding family B member 2, peptide from Amyloid beta A4 protein | 著者 | Li, H, Koshiba, S, Tochio, N, Watanabe, S, Harada, T, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2008-04-25 | 公開日 | 2008-07-22 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of the C-terminal phosphotyrosine interaction domain of Fe65L1 complexed with the cytoplasmic tail of amyloid precursor protein reveals a novel peptide binding mode J.Biol.Chem., 283, 2008
|
|
6PGO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6pgo by Molmil](/molmil-images/mine/6pgo) | |
6PGP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6pgp by Molmil](/molmil-images/mine/6pgp) | |
7SR8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7sr8 by Molmil](/molmil-images/mine/7sr8) | Molecular mechanism of the the wake-promoting agent TAK-925 | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Hypocretin receptor type 2, ... | 著者 | Yin, J, Chapman, K, Lian, P, De Brabander, J.K, Rosenbaum, D.M. | 登録日 | 2021-11-08 | 公開日 | 2022-06-08 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Molecular mechanism of the wake-promoting agent TAK-925. Nat Commun, 13, 2022
|
|
6OR6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6or6 by Molmil](/molmil-images/mine/6or6) | Full-length S. pombe Mdn1 in the presence of AMPPNP (tail region) | 分子名称: | Midasin | 著者 | Chen, Z, Suzuki, H, Wang, A.C, DiMaio, F, Walz, T, Kapoor, T.M. | 登録日 | 2019-04-29 | 公開日 | 2019-05-29 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (5.3 Å) | 主引用文献 | Structural Insights into Mdn1, an Essential AAA Protein Required for Ribosome Biogenesis. Cell, 175, 2018
|
|
6OR5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6or5 by Molmil](/molmil-images/mine/6or5) | Full-length S. pombe Mdn1 in the presence of AMPPNP (ring region) | 分子名称: | Midasin, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | 著者 | Chen, Z, Suzuki, H, Wang, A.C, DiMaio, F, Walz, T, Kapoor, T.M. | 登録日 | 2019-04-29 | 公開日 | 2019-05-29 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Structural Insights into Mdn1, an Essential AAA Protein Required for Ribosome Biogenesis. Cell, 175, 2018
|
|
4EBV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ebv by Molmil](/molmil-images/mine/4ebv) | Structure of Focal Adhesion Kinase catalytic domain in complex with novel allosteric inhibitor | 分子名称: | 8-(4-ethylphenyl)-5-methyl-2,5-dihydropyrazolo[4,3-c][2,1]benzothiazine 4,4-dioxide, Focal adhesion kinase 1, ISOPROPYL ALCOHOL | 著者 | Skene, R.J, Hosfield, D.J. | 登録日 | 2012-03-25 | 公開日 | 2012-08-22 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | 主引用文献 | Discovery and characterization of novel allosteric FAK inhibitors. Eur.J.Med.Chem., 61, 2013
|
|
6ORB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6orb by Molmil](/molmil-images/mine/6orb) | Full-length S. pombe Mdn1 in the presence of ATP and Rbin-1 | 分子名称: | Midasin | 著者 | Chen, Z, Suzuki, H, Wang, A.C, DiMaio, F, Walz, T, Kapoor, T.M. | 登録日 | 2019-04-29 | 公開日 | 2019-05-29 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (7.7 Å) | 主引用文献 | Structural Insights into Mdn1, an Essential AAA Protein Required for Ribosome Biogenesis. Cell, 175, 2018
|
|
8E22
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8e22 by Molmil](/molmil-images/mine/8e22) | VPS37A_21-148 | 分子名称: | Vacuolar protein sorting-associated protein 37A | 著者 | Tian, F, Ye, Y.S. | 登録日 | 2022-08-12 | 公開日 | 2023-08-09 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Identification of membrane curvature sensing motifs essential for VPS37A phagophore recruitment and autophagosome closure. Commun Biol, 7, 2024
|
|
3I8U
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3i8u by Molmil](/molmil-images/mine/3i8u) | Crystal structure of PcyA-181,182-dihydrobiliverdin complex | 分子名称: | 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(3-ethenyl-4-methyl-5-oxo-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-2-ylidene]methy l]-5-[(Z)-(4-ethyl-3-methyl-5-oxo-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid, Phycocyanobilin:ferredoxin oxidoreductase | 著者 | Hagiwara, Y, Sugishima, M, Fukuyama, K. | 登録日 | 2009-07-10 | 公開日 | 2009-10-27 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | 主引用文献 | Structural insights into vinyl reduction regiospecificity of phycocyanobilin:ferredoxin oxidoreductase (PcyA). To be Published
|
|
3I95
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3i95 by Molmil](/molmil-images/mine/3i95) | |
6UIN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6uin by Molmil](/molmil-images/mine/6uin) | |
4XY2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4xy2 by Molmil](/molmil-images/mine/4xy2) | Crystal structure of PDE10A in complex with ASP9436 | 分子名称: | 1-methyl-5-(1-methyl-3-{[4-(1-methyl-1H-benzimidazol-4-yl)phenoxy]methyl}-1H-pyrazol-4-yl)pyridin-2(1H)-one, MAGNESIUM ION, ZINC ION, ... | 著者 | Amano, Y, Honbou, K. | 登録日 | 2015-02-02 | 公開日 | 2015-06-17 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | Addressing phototoxicity observed in a novel series of biaryl derivatives: Discovery of potent, selective and orally active phosphodiesterase 10A inhibitor ASP9436 Bioorg.Med.Chem., 23, 2015
|
|
6UG1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ug1 by Molmil](/molmil-images/mine/6ug1) | |
8GU3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8gu3 by Molmil](/molmil-images/mine/8gu3) | |
7BI1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7bi1 by Molmil](/molmil-images/mine/7bi1) | XFEL crystal structure of soybean ascorbate peroxidase compound II | 分子名称: | Ascorbate peroxidase, POTASSIUM ION, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Kwon, H, Tosha, T, Sugimoto, H, Raven, E.L, Moody, P.C.E. | 登録日 | 2021-01-12 | 公開日 | 2021-04-21 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | XFEL Crystal Structures of Peroxidase Compound II. Angew.Chem.Int.Ed.Engl., 60, 2021
|
|
7BIU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7biu by Molmil](/molmil-images/mine/7biu) | XFEL crystal structure of cytochrome c peroxidase compound II | 分子名称: | Cytochrome c peroxidase, mitochondrial, HEME C | 著者 | Kwon, H, Tosha, T, Sugimoto, H, Raven, E.L, Moody, P.C.E. | 登録日 | 2021-01-13 | 公開日 | 2021-04-21 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.06 Å) | 主引用文献 | XFEL Crystal Structures of Peroxidase Compound II. Angew.Chem.Int.Ed.Engl., 60, 2021
|
|
5AWO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5awo by Molmil](/molmil-images/mine/5awo) | Arthrobacter globiformis T6 isomalto-dextranse | 分子名称: | ACETATE ION, Isomaltodextranase, PHOSPHATE ION | 著者 | Tonozuka, T. | 登録日 | 2015-07-08 | 公開日 | 2015-09-09 | 最終更新日 | 2020-02-26 | 実験手法 | X-RAY DIFFRACTION (1.44 Å) | 主引用文献 | Crystal Structure and Mutational Analysis of Isomalto-dextranase, a Member of Glycoside Hydrolase Family 27 J.Biol.Chem., 290, 2015
|
|
4YSH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ysh by Molmil](/molmil-images/mine/4ysh) | |
5AWP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5awp by Molmil](/molmil-images/mine/5awp) | |
5AWQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5awq by Molmil](/molmil-images/mine/5awq) | |