7DVB
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![BU of 7dvb by Molmil](/molmil-images/mine/7dvb) | D335N variant of Bt4394 in complex with 6SO3-NAG-oxazoline intermediate | 分子名称: | 2-acetamido-2-deoxy-6-O-sulfo-beta-D-glucopyranose, Beta-N-acetylhexosaminidase, [(3~{a}~{R},5~{R},6~{S},7~{R},7~{a}~{R})-2-methyl-6,7-bis(oxidanyl)-5,6,7,7~{a}-tetrahydro-3~{a}~{H}-pyrano[3,2-d][1,3]oxazol-1-ium-5-yl]methyl sulfate | 著者 | Zhang, Z, He, Y, Jin, Y. | 登録日 | 2021-01-13 | 公開日 | 2022-01-19 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Mechanistic and Structural Insights into the Specificity and Biological Functions of Bacterial Sulfoglycosidases Acs Catalysis, 13, 2023
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7WGE
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![BU of 7wge by Molmil](/molmil-images/mine/7wge) | Human NLRP1 complexed with thioredoxin | 分子名称: | MAGNESIUM ION, NACHT, LRR and PYD domains-containing protein 1, ... | 著者 | Zhang, Z, Ohto, U, Shimizu, T. | 登録日 | 2021-12-28 | 公開日 | 2023-07-05 | 最終更新日 | 2023-10-18 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural basis for thioredoxin-mediated suppression of NLRP1 inflammasome. Nature, 622, 2023
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7XME
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5LUN
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![BU of 5lun by Molmil](/molmil-images/mine/5lun) | Ethylene Forming Enzyme from Pseudomonas syringae pv. phaseolicola - P1 ultra-high resolution crystal form in complex with iron, N-oxalylglycine and arginine | 分子名称: | 2-oxoglutarate-dependent ethylene/succinate-forming enzyme, ARGININE, FE (III) ION, ... | 著者 | McDonough, M.A, Zhang, Z, Schofield, C.J. | 登録日 | 2016-09-09 | 公開日 | 2017-04-19 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.08 Å) | 主引用文献 | Structural and stereoelectronic insights into oxygenase-catalyzed formation of ethylene from 2-oxoglutarate. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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6O1V
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![BU of 6o1v by Molmil](/molmil-images/mine/6o1v) | Complex of human cystic fibrosis transmembrane conductance regulator (CFTR) and GLPG1837 | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ADENOSINE-5'-TRIPHOSPHATE, CHOLESTEROL, ... | 著者 | Zhang, Z, Liu, F, Chen, J, Levit, A, Shoichet, B. | 登録日 | 2019-02-21 | 公開日 | 2019-06-26 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural identification of a hotspot on CFTR for potentiation. Science, 364, 2019
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1TPC
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![BU of 1tpc by Molmil](/molmil-images/mine/1tpc) | OFFSET OF A CATALYTIC LESION BY A BOUND WATER SOLUBLE | 分子名称: | PHOSPHOGLYCOLOHYDROXAMIC ACID, TRIOSEPHOSPHATE ISOMERASE | 著者 | Zhang, Z, Sugio, S, Komives, E.A, Liu, K.D, Knowles, J.R, Petsko, G.A, Ringe, D. | 登録日 | 1994-02-03 | 公開日 | 1995-02-14 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The structural basis for pseudoreversion of the E165D lesion by the secondary S96P mutation in triosephosphate isomerase depends on the positions of active site water molecules. Biochemistry, 34, 1995
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1TPB
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![BU of 1tpb by Molmil](/molmil-images/mine/1tpb) | OFFSET OF A CATALYTIC LESION BY A BOUND WATER SOLUBLE | 分子名称: | PHOSPHOGLYCOLOHYDROXAMIC ACID, TRIOSEPHOSPHATE ISOMERASE | 著者 | Zhang, Z, Sugio, S, Komives, E.A, Liu, K.D, Knowles, J.R, Petsko, G.A, Ringe, D. | 登録日 | 1994-02-03 | 公開日 | 1995-02-14 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The structural basis for pseudoreversion of the E165D lesion by the secondary S96P mutation in triosephosphate isomerase depends on the positions of active site water molecules. Biochemistry, 34, 1995
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8ZMR
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![BU of 8zmr by Molmil](/molmil-images/mine/8zmr) | Vesamicol-bound VAChT | 分子名称: | Maltose/maltodextrin-binding periplasmic protein,Vesicular acetylcholine transporter,DARPinoff7, vesamicol | 著者 | Zhang, Z, Zhang, Y, Dai, F, Zhang, Y.X, Lee, C.-H. | 登録日 | 2024-05-23 | 公開日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structural insights into VAChT neurotransmitter recognition and inhibition. Cell Res., 2024
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8ZMS
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![BU of 8zms by Molmil](/molmil-images/mine/8zms) | Acetylcholine-bound VAChT | 分子名称: | ACETYLCHOLINE, Maltose/maltodextrin-binding periplasmic protein,Vesicular acetylcholine transporter,DARPinoff7 | 著者 | Zhang, Z, Zhang, Y, Dai, F, Zhang, Y.X, Lee, C.-H. | 登録日 | 2024-05-23 | 公開日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structural insights into VAChT neurotransmitter recognition and inhibition. Cell Res., 2024
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1TPU
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![BU of 1tpu by Molmil](/molmil-images/mine/1tpu) | S96P CHANGE IS A SECOND-SITE SUPPRESSOR FOR H95N SLUGGISH MUTANT TRIOSEPHOSPHATE ISOMERASE | 分子名称: | PHOSPHOGLYCOLOHYDROXAMIC ACID, TRIOSEPHOSPHATE ISOMERASE | 著者 | Zhang, Z, Sugio, S, Komives, E.A, Liu, K.D, Stock, A.M, Narayana, N, Xuong, Ng.H, Knowles, J.R, Petsko, G.A, Ringe, D. | 登録日 | 1994-11-07 | 公開日 | 1995-04-20 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The structural basis for pseudoreversion of the H95N lesion by the secondary S96P mutation in triosephosphate isomerase. Biochemistry, 35, 1996
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1TPV
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![BU of 1tpv by Molmil](/molmil-images/mine/1tpv) | S96P CHANGE IS A SECOND-SITE SUPPRESSOR FOR H95N SLUGGISH MUTANT TRIOSEPHOSPHATE ISOMERASE | 分子名称: | PHOSPHOGLYCOLOHYDROXAMIC ACID, TRIOSEPHOSPHATE ISOMERASE | 著者 | Zhang, Z, Sugio, S, Komives, E.A, Liu, K.D, Stock, A.M, Narayana, N, Xuong, Ng.H, Knowles, J.R, Petsko, G.A, Ringe, D. | 登録日 | 1994-11-07 | 公開日 | 1995-04-20 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The structural basis for pseudoreversion of the H95N lesion by the secondary S96P mutation in triosephosphate isomerase. Biochemistry, 35, 1996
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1X11
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![BU of 1x11 by Molmil](/molmil-images/mine/1x11) | X11 PTB DOMAIN | 分子名称: | 13-MER PEPTIDE, X11 | 著者 | Lee, C.-H, Zhang, Z, Kuriyan, J. | 登録日 | 1997-07-28 | 公開日 | 1998-01-14 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Sequence-specific recognition of the internalization motif of the Alzheimer's amyloid precursor protein by the X11 PTB domain. EMBO J., 16, 1997
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1AQC
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5MOF
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![BU of 5mof by Molmil](/molmil-images/mine/5mof) | Ethylene Forming Enzyme from Pseudomonas syringae pv. phaseolicola - I222 crystal form in complex with manganese and 2-oxoglutarate | 分子名称: | 2-OXOGLUTARIC ACID, 2-oxoglutarate-dependent ethylene/succinate-forming enzyme, CHLORIDE ION, ... | 著者 | McDonough, M.A, Zhang, Z, Schofield, C.J. | 登録日 | 2016-12-14 | 公開日 | 2017-04-19 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Structural and stereoelectronic insights into oxygenase-catalyzed formation of ethylene from 2-oxoglutarate. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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4XPU
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5JO4
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![BU of 5jo4 by Molmil](/molmil-images/mine/5jo4) | Antibody Fab Fragment Complex | 分子名称: | D80 Fab Heavy Chain, D80 Fab Light Chain, G6 Fab Heavy Chain, ... | 著者 | Zhang, Z, Prachanronarong, K.P, Marasco, W.A, Schiffer, C.A.S. | 登録日 | 2016-05-01 | 公開日 | 2017-11-08 | 最終更新日 | 2019-11-27 | 実験手法 | X-RAY DIFFRACTION (2.53 Å) | 主引用文献 | Structural Basis of an Influenza Hemagglutinin Stem-Directed Antibody Retaining the G6 Idiotype To Be Published
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5JQD
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![BU of 5jqd by Molmil](/molmil-images/mine/5jqd) | Antibody Fab Fragment | 分子名称: | D80 Fab Fragment Heavy Chain, D80 Fab Fragment Light Chain | 著者 | Zhang, Z, Prachanronarong, K, Gellatly, K, Marasco, W.A, Schiffer, C.A. | 登録日 | 2016-05-04 | 公開日 | 2017-11-08 | 最終更新日 | 2019-11-27 | 実験手法 | X-RAY DIFFRACTION (2.591 Å) | 主引用文献 | Structural Basis of an Influenza Hemagglutinin Stem-Directed Antibody Retaining the G6 Idiotype To Be Published
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4NSP
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3KAE
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![BU of 3kae by Molmil](/molmil-images/mine/3kae) | Cdc27 N-terminus | 分子名称: | CHLORIDE ION, GLYCEROL, Possible protein of nuclear scaffold, ... | 著者 | Barford, D, Zhang, Z, Roe, S.M. | 登録日 | 2009-10-19 | 公開日 | 2010-03-23 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.298 Å) | 主引用文献 | Molecular structure of the N-terminal domain of the APC/C subunit Cdc27 reveals a homo-dimeric tetratricopeptide repeat architecture J.Mol.Biol., 397, 2010
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8Y3X
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![BU of 8y3x by Molmil](/molmil-images/mine/8y3x) | Cell divisome sPG hydrolysis machinery FtsEX-EnvC | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Cell division ATP-binding protein FtsE, Cell division protein FtsX, ... | 著者 | Zhang, Z, Dong, H, Chen, Y. | 登録日 | 2024-01-29 | 公開日 | 2024-05-08 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.11 Å) | 主引用文献 | Structure and activity of the septal peptidoglycan hydrolysis machinery crucial for bacterial cell division. Plos Biol., 22, 2024
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3PX7
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5WRO
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![BU of 5wro by Molmil](/molmil-images/mine/5wro) | Crystal structure of Drosophila enolase | 分子名称: | CADMIUM ION, CHLORIDE ION, COBALT (II) ION, ... | 著者 | Zhang, Z, Shi, Z. | 登録日 | 2016-12-02 | 公開日 | 2017-04-26 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.015 Å) | 主引用文献 | Crystal structure of enolase from Drosophila melanogaster. Acta Crystallogr F Struct Biol Commun, 73, 2017
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6K9H
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![BU of 6k9h by Molmil](/molmil-images/mine/6k9h) | Human LXR-beta in complex with an agonist | 分子名称: | Oxysterols receptor LXR-beta, ~{tert}-butyl (2'~{S},3~{S})-2-oxidanylidene-2'-phenyl-spiro[1~{H}-indole-3,3'-pyrrolidine]-1'-carboxylate | 著者 | Zhang, Z, Zhou, H. | 登録日 | 2019-06-15 | 公開日 | 2020-04-22 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Discovery of new LXR beta agonists as glioblastoma inhibitors. Eur.J.Med.Chem., 194, 2020
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6K10
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6K9M
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![BU of 6k9m by Molmil](/molmil-images/mine/6k9m) | Human LXR-beta in complex with an agonist | 分子名称: | Oxysterols receptor LXR-beta, ~{tert}-butyl (2'~{S},3~{S})-2-oxidanylidene-2'-propan-2-yl-spiro[1~{H}-indole-3,3'-pyrrolidine]-1'-carboxylate | 著者 | Zhang, Z, Zhou, H. | 登録日 | 2019-06-16 | 公開日 | 2020-06-17 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Discovery of novel liver X receptor inverse agonists as lipogenesis inhibitors. Eur.J.Med.Chem., 206, 2020
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