3BV6
 
 | | Crystal structure of uncharacterized metallo protein from Vibrio cholerae with beta-lactamase like fold | | 分子名称: | FE (III) ION, Metal-dependent hydrolase | | 著者 | Minasov, G, Shuvalova, L, Brunzelle, J.S, Yang, X, Collart, F.R, Joachimiak, A, Anderson, W.F, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2008-01-04 | | 公開日 | 2008-01-29 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structure of uncharacterized metallo protein from Vibrio cholerae with beta-lactamase like fold.
To be Published
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3Q54
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8VSJ
 | | Engineered peptide-specific binder in complex with HLA-DR1/CLIP | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Class-II-associated invariant chain peptide, HLA class II histocompatibility antigen DR beta chain, ... | | 著者 | Jude, K.M, Yang, X, Du, H, Kassardjian, A, Julien, J.-P, Huang, P, Garcia, K.C. | | 登録日 | 2024-01-24 | | 公開日 | 2024-10-02 | | 最終更新日 | 2025-02-19 | | 実験手法 | ELECTRON MICROSCOPY (2.28 Å) | | 主引用文献 | A general system for targeting MHC class II-antigen complex via a single adaptable loop.
Nat.Biotechnol., 2024
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8HNV
 | | CryoEM structure of HpaCas9-sgRNA-dsDNA in the presence of AcrIIC4 | | 分子名称: | CRISPR-associated endonuclease Cas9, anti-CRISPR protein AcrIIC4, non-target strand, ... | | 著者 | Sun, W, Cheng, Z, Wang, J, Yang, X, Wang, Y. | | 登録日 | 2022-12-08 | | 公開日 | 2023-07-19 | | 最終更新日 | 2025-07-02 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | AcrIIC4 inhibits type II-C Cas9 by preventing R-loop formation.
Proc.Natl.Acad.Sci.USA, 120, 2023
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3Q5M
 | | Crystal structure of Escherichia coli BamD | | 分子名称: | IODIDE ION, UPF0169 lipoprotein yfiO | | 著者 | Dong, C, Hou, H, Yang, X, Dong, Y, Shen, Y. | | 登録日 | 2010-12-28 | | 公開日 | 2011-12-28 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.604 Å) | | 主引用文献 | Structure of Escherichia coli BamD and its functional implications in outer membrane protein assembly
Acta Crystallogr.,Sect.D, 68, 2012
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4PO5
 | | Crystal structure of allophycocyanin B from Synechocystis PCC 6803 | | 分子名称: | Allophycocyanin beta chain, Allophycocyanin subunit alpha-B, PHYCOCYANOBILIN, ... | | 著者 | Pang, P.P, Dong, L.L, Sun, Y.F, Zeng, X.L, Ding, W.L, Scheer, H, Yang, X, Zhao, K.H. | | 登録日 | 2014-02-24 | | 公開日 | 2014-10-29 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.751 Å) | | 主引用文献 | The structure of allophycocyanin B from Synechocystis PCC 6803 reveals the structural basis for the extreme redshift of the terminal emitter in phycobilisomes.
Acta Crystallogr.,Sect.D, 70, 2014
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3UIU
 | | Crystal structure of Apo-PKR kinase domain | | 分子名称: | Interferon-induced, double-stranded RNA-activated protein kinase | | 著者 | Li, F, Li, S, Yang, X, Shen, Y, Zhang, T. | | 登録日 | 2011-11-06 | | 公開日 | 2012-11-07 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.903 Å) | | 主引用文献 | Crystal structure of Apo-PKR kinase domain
TO BE PUBLISHED
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3UE6
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3ULF
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4R3Q
 | | Crystal structure of SYCE3 | | 分子名称: | Synaptonemal complex central element protein 3 | | 著者 | Lu, J, Feng, J, Zhou, W, Yang, X, Shen, Y. | | 登録日 | 2014-08-17 | | 公開日 | 2014-11-26 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.901 Å) | | 主引用文献 | Structural insight into the central element assembly of the synaptonemal complex
Sci Rep, 4, 2014
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6J44
 | | Crystal structure of the redefined DNA-binding domain of human XPA | | 分子名称: | DNA repair protein complementing XP-A cells, ZINC ION | | 著者 | Lian, F.M, Yang, X, Yang, W, Jiang, Y.L, Qian, C. | | 登録日 | 2019-01-07 | | 公開日 | 2019-05-29 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | | 主引用文献 | Structural characterization of the redefined DNA-binding domain of human XPA.
Biochem.Biophys.Res.Commun., 514, 2019
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4NSC
 | | Crystal Structure of CBARA1 in the Apo-form | | 分子名称: | Calcium uptake protein 1, mitochondrial | | 著者 | Wang, L, Yang, X, Li, S, Shen, Y. | | 登録日 | 2013-11-28 | | 公開日 | 2014-02-26 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural and mechanistic insights into MICU1 regulation of mitochondrial calcium uptake.
Embo J., 33, 2014
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4NSD
 | | Crystal Structure of CBARA1 in the Ca2+ Binding Form | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Wang, L, Yang, X, Li, S, Shen, Y. | | 登録日 | 2013-11-28 | | 公開日 | 2014-02-26 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural and mechanistic insights into MICU1 regulation of mitochondrial calcium uptake.
Embo J., 33, 2014
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4O4S
 | | Crystal structure of phycobiliprotein lyase CpcT complexed with phycocyanobilin (PCB) | | 分子名称: | PHYCOCYANOBILIN, Phycocyanobilin lyase CpcT | | 著者 | Zhou, W, Ding, W.-L, Zeng, X.-l, Dong, L.-L, Zhao, B, Zhou, M, Scheer, H, Zhao, K.-H, Yang, X. | | 登録日 | 2013-12-19 | | 公開日 | 2014-08-13 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure and Mechanism of the Phycobiliprotein Lyase CpcT.
J.Biol.Chem., 289, 2014
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4O4O
 | | Crystal structure of phycobiliprotein lyase CpcT | | 分子名称: | MAGNESIUM ION, Phycocyanobilin lyase CpcT | | 著者 | Zhou, W, Ding, W.-L, Zeng, X.-l, Dong, L.-L, Zhao, B, Zhou, M, Scheer, H, Zhao, K.-H, Yang, X. | | 登録日 | 2013-12-19 | | 公開日 | 2014-08-06 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structure and Mechanism of the Phycobiliprotein Lyase CpcT.
J.Biol.Chem., 289, 2014
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4O9B
 | | The Structure of CC1-IH in human STIM1. | | 分子名称: | CADMIUM ION, Stromal interaction molecule 1 | | 著者 | Cui, B, Yang, X, Li, S, Shen, Y. | | 登録日 | 2014-01-02 | | 公開日 | 2014-01-15 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.604 Å) | | 主引用文献 | The inhibitory helix controls the intramolecular conformational switching of the C-terminus of STIM1.
Plos One, 8, 2013
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7YR7
 | | Cryo-EM structure of Pseudomonas aeruginosa RsmZ RNA in complex with three RsmA protein dimers | | 分子名称: | RsmZ RNA (118-MER), Translational regulator CsrA | | 著者 | Jia, X, Pan, Z, Yuan, Y, Luo, B, Luo, Y, Mukherjee, S, Jia, G, Liu, L, Ling, X, Yang, X, Wu, Y, Liu, T, Miao, Z, Wei, X, Bujnicki, J.M, Zhao, K, Su, Z. | | 登録日 | 2022-08-09 | | 公開日 | 2023-05-17 | | 最終更新日 | 2025-03-12 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Structural basis of sRNA RsmZ regulation of Pseudomonas aeruginosa virulence.
Cell Res., 33, 2023
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7YR6
 | | Cryo-EM structure of Pseudomonas aeruginosa RsmZ RNA in complex with two RsmA protein dimers | | 分子名称: | RsmZ RNA, Translational regulator CsrA | | 著者 | Jia, X, Pan, Z, Yuan, Y, Luo, B, Luo, Y, Mukherjee, S, Jia, G, Ling, X, Yang, X, Wu, Y, Liu, T, Wei, X, Bujnick, J.M, Zhao, K, Su, Z. | | 登録日 | 2022-08-09 | | 公開日 | 2023-05-17 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | | 主引用文献 | Structural basis of sRNA RsmZ regulation of Pseudomonas aeruginosa virulence.
Cell Res., 33, 2023
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4I16
 | | Crystal structure of CARMA1 CARD | | 分子名称: | Caspase recruitment domain-containing protein 11, SULFATE ION | | 著者 | Li, S, Yang, X, Shen, Y. | | 登録日 | 2012-11-20 | | 公開日 | 2012-12-26 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.751 Å) | | 主引用文献 | Structural insights into the assembly of CARMA1 and BCL10
Plos One, 7, 2012
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7WNX
 | | Cryo-EM structure of Mycobacterium smegmatis MmpL3 complexed with ST004 in lipid nanodiscs | | 分子名称: | N-[2-(2-adamantylamino)ethyl]-1-[2,4-bis(fluoranyl)phenyl]-5-(4-chlorophenyl)-4-methyl-pyrazole-3-carboxamide, Trehalose monomycolate exporter MmpL3 | | 著者 | Zhang, B, Hu, T, Yang, X, Liu, F, Rao, Z. | | 登録日 | 2022-01-20 | | 公開日 | 2022-08-03 | | 最終更新日 | 2024-04-10 | | 実験手法 | ELECTRON MICROSCOPY (3.36 Å) | | 主引用文献 | Structure-based design of anti-mycobacterial drug leads that target the mycolic acid transporter MmpL3.
Structure, 30, 2022
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9F21
 | | Crystal structure of Borrelia burgdorferi CspZ-YACS | | 分子名称: | Complement regulator-acquiring surface protein 2 (CRASP-2), SULFATE ION | | 著者 | Brangulis, K, Malfetano, J, Marcinkiewicz, A.L, Wang, A, Chen, Y.-L, Yang, X, Lee, W, Bottazzi, M.-E, Pal, U, Hsieh, C.-L, Chen, W.-H, Lin, Y.-P. | | 登録日 | 2024-04-20 | | 公開日 | 2025-04-16 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Mechanistic insights into the structure-based design of a CspZ-targeting Lyme disease vaccine.
Nat Commun, 16, 2025
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9F1V
 | | Crystal structure of Borrelia burgdorferi CspZ-YA | | 分子名称: | Complement regulator-acquiring surface protein 2 (CRASP-2) | | 著者 | Brangulis, K, Malfetano, J, Marcinkiewicz, A.L, Wang, A, Chen, Y.-L, Yang, X, Lee, W, Bottazzi, M.-E, Pal, U, Hsieh, C.-L, Chen, W.-H, Lin, Y.-P. | | 登録日 | 2024-04-20 | | 公開日 | 2025-04-16 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Mechanistic insights into the structure-based design of a CspZ-targeting Lyme disease vaccine.
Nat Commun, 16, 2025
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9FYF
 | | Crystal structure of human Casein Kinase II subunit alpha (CK2a1) in complex with TR06772818 | | 分子名称: | Casein kinase II subunit alpha, SULFATE ION, ~{N}-[5-[[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]amino]-4-fluoranyl-2-[(3~{S})-3-(methylamino)piperidin-1-yl]phenyl]propanamide | | 著者 | Kraemer, A, Ong, H.W, Yang, X, Brown, J.W, Chang, E, Willson, T, Knapp, S, Structural Genomics Consortium (SGC) | | 登録日 | 2024-07-03 | | 公開日 | 2024-09-11 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structure of human Casein Kinase II subunit alpha (CK2a1) in complex with TR06772818
To Be Published
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9EZG
 | | Crystal structure of human Casein Kinase II subunit alpha (CK2a1) in complex with 5-((4-((2-aminoethyl)(ethyl)amino)-3-(4H-1,2,4-triazol-4-yl)phenyl)amino)-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidine-3-carbonitrile | | 分子名称: | 1,2-ETHANEDIOL, 5-[[4-[2-azanylethyl(ethyl)amino]-3-(1,2,4-triazol-4-yl)phenyl]amino]-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidine-3-carbonitrile, Casein kinase II subunit alpha, ... | | 著者 | Kraemer, A, Ong, H.W, Yang, X, Brown, J.W, Chang, E, Willson, T, Knapp, S, Structural Genomics Consortium (SGC) | | 登録日 | 2024-04-12 | | 公開日 | 2024-07-31 | | 最終更新日 | 2024-08-07 | | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | | 主引用文献 | More than an Amide Bioisostere: Discovery of 1,2,4-Triazole-containing Pyrazolo[1,5- a ]pyrimidine Host CSNK2 Inhibitors for Combatting beta-Coronavirus Replication.
J.Med.Chem., 67, 2024
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7Y1Q
 | | 5.0 angstrom cryo-EM structure of transmembrane regions of mouse Basigin/MCT1 in complex with antibody 6E7F1 | | 分子名称: | Isoform 2 of Basigin, Monocarboxylate transporter 1 | | 著者 | Zhang, H, Yang, X, Xue, Y, Huang, Y, Mo, X, Zhang, H, Li, N, Gao, N, Li, X, Wang, S, Gao, Y, Liao, J. | | 登録日 | 2022-06-08 | | 公開日 | 2023-06-14 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (5.03 Å) | | 主引用文献 | Allosteric modulation of monocarboxylate transporters 1 and 4 by targeting their chaperon Basigin-2
To Be Published
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