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8HD8
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BU of 8hd8 by Molmil
Crystal structure of TMPRSS2 in complex with 212-148
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-carbamimidamidobenzoic acid, CALCIUM ION, ...
著者Wang, H, Liu, X, Sun, L, Yang, H.
登録日2022-11-03
公開日2023-12-13
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure-based discovery of dual pathway inhibitors for SARS-CoV-2 entry.
Nat Commun, 14, 2023
8HE9
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BU of 8he9 by Molmil
Crystal structure of CTSB in complex with K777
分子名称: Cathepsin B, DIMETHYL SULFOXIDE, GLYCEROL, ...
著者Wang, H, Li, D, Sun, L, Yang, H.
登録日2022-11-07
公開日2023-12-13
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structure-based discovery of dual pathway inhibitors for SARS-CoV-2 entry.
Nat Commun, 14, 2023
8HEN
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BU of 8hen by Molmil
Crystal structure of CTSB in complex with 212-148
分子名称: 2-[4-[[(2~{S})-1-oxidanylidene-3-phenyl-1-[[(3~{S})-1-phenyl-5-(phenylsulfonyl)pentan-3-yl]amino]propan-2-yl]carbamoyl]piperazin-1-yl]ethyl 4-carbamimidamidobenzoate, Cathepsin B, DIMETHYL SULFOXIDE, ...
著者Wang, H, Li, D, Sun, L, Yang, H.
登録日2022-11-08
公開日2023-12-13
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structure-based discovery of dual pathway inhibitors for SARS-CoV-2 entry.
Nat Commun, 14, 2023
8HFV
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BU of 8hfv by Molmil
Crystal structure of CTSL in complex with K777
分子名称: CACODYLATE ION, Nalpha-[(4-methylpiperazin-1-yl)carbonyl]-N-[(3S)-1-phenyl-5-(phenylsulfonyl)pentan-3-yl]-L-phenylalaninamide, Procathepsin L, ...
著者Wang, H, Shao, M, Sun, L, Yang, H.
登録日2022-11-12
公開日2023-12-13
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure-based discovery of dual pathway inhibitors for SARS-CoV-2 entry.
Nat Commun, 14, 2023
7VY0
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BU of 7vy0 by Molmil
Coxsackievirus B3 full particle at pH7.4 (VP3-234N)
分子名称: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
著者Wang, Q.L, Liu, C.C.
登録日2021-11-13
公開日2022-01-19
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Molecular basis of differential receptor usage for naturally occurring CD55-binding and -nonbinding coxsackievirus B3 strains.
Proc.Natl.Acad.Sci.USA, 119, 2022
7VY6
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BU of 7vy6 by Molmil
Coxsackievirus B3(VP3-234N) incubate with CD55 at pH7.4
分子名称: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
著者Wang, Q.L, Liu, C.C.
登録日2021-11-13
公開日2022-01-19
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (3.02 Å)
主引用文献Molecular basis of differential receptor usage for naturally occurring CD55-binding and -nonbinding coxsackievirus B3 strains.
Proc.Natl.Acad.Sci.USA, 119, 2022
7W14
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BU of 7w14 by Molmil
Coxsackievirus B3 at pH7.4 (VP3-234E) incubation with coxsackievirus and adenovirus receptor for 20min
分子名称: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
著者Wang, Q.L, Liu, C.C.
登録日2021-11-19
公開日2022-01-19
最終更新日2022-08-03
実験手法ELECTRON MICROSCOPY (2.2 Å)
主引用文献Molecular basis of differential receptor usage for naturally occurring CD55-binding and -nonbinding coxsackievirus B3 strains.
Proc.Natl.Acad.Sci.USA, 119, 2022
7VYL
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BU of 7vyl by Molmil
Coxsackievirus B3 at pH5.5 (VP3-234Q) incubation with coxsackievirus and adenovirus receptor for 20min
分子名称: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
著者Wang, Q.L, Liu, C.C.
登録日2021-11-14
公開日2022-01-19
最終更新日2022-08-10
実験手法ELECTRON MICROSCOPY (2.79 Å)
主引用文献Molecular basis of differential receptor usage for naturally occurring CD55-binding and -nonbinding coxsackievirus B3 strains.
Proc.Natl.Acad.Sci.USA, 119, 2022
7VY5
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BU of 7vy5 by Molmil
Coxsackievirus B3 (VP3-234Q) incubation with CD55 at pH7.4
分子名称: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
著者Wang, Q.L, Liu, C.C.
登録日2021-11-13
公開日2022-01-19
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (3.15 Å)
主引用文献Molecular basis of differential receptor usage for naturally occurring CD55-binding and -nonbinding coxsackievirus B3 strains.
Proc.Natl.Acad.Sci.USA, 119, 2022
7VXZ
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BU of 7vxz by Molmil
Coxsackievirus B3 at pH7.4 (VP3-234Q) incubation with coxsackievirus and adenovirus receptor for 20min
分子名称: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
著者Wang, Q.L, Liu, C.C.
登録日2021-11-13
公開日2022-01-19
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.19 Å)
主引用文献Molecular basis of differential receptor usage for naturally occurring CD55-binding and -nonbinding coxsackievirus B3 strains.
Proc.Natl.Acad.Sci.USA, 119, 2022
7W17
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BU of 7w17 by Molmil
Coxsackievirus B3 full particle at pH7.4 (VP3-234E)
分子名称: PALMITIC ACID, VP1, VP2, ...
著者Wang, Q.L, Liu, C.C.
登録日2021-11-19
公開日2022-01-19
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Molecular basis of differential receptor usage for naturally occurring CD55-binding and -nonbinding coxsackievirus B3 strains.
Proc.Natl.Acad.Sci.USA, 119, 2022
7VYK
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BU of 7vyk by Molmil
Coxsackievirus B3 at pH7.4 (VP3-234Q) incubation with coxsackievirus and adenovirus receptor for 10min
分子名称: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
著者Wang, Q.L, Liu, C.C.
登録日2021-11-14
公開日2022-01-19
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (2.79 Å)
主引用文献Molecular basis of differential receptor usage for naturally occurring CD55-binding and -nonbinding coxsackievirus B3 strains.
Proc.Natl.Acad.Sci.USA, 119, 2022
7VYM
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BU of 7vym by Molmil
Coxsackievirus B3 at pH7.4 (VP3-234E) incubation with coxsackievirus and adenovirus receptor for 10min
分子名称: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
著者Wang, Q.L, Liu, C.C.
登録日2021-11-14
公開日2022-01-19
最終更新日2022-08-10
実験手法ELECTRON MICROSCOPY (3.68 Å)
主引用文献Molecular basis of differential receptor usage for naturally occurring CD55-binding and -nonbinding coxsackievirus B3 strains.
Proc.Natl.Acad.Sci.USA, 119, 2022
7VXH
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BU of 7vxh by Molmil
Coxsackievirus B3 full particle at pH7.4 (VP3-234Q)
分子名称: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
著者Wang, Q.L, Liu, C.C.
登録日2021-11-12
公開日2022-01-19
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (2.95 Å)
主引用文献Molecular basis of differential receptor usage for naturally occurring CD55-binding and -nonbinding coxsackievirus B3 strains.
Proc.Natl.Acad.Sci.USA, 119, 2022
8J69
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BU of 8j69 by Molmil
Crystal structure of HORMA domain-containing protein 1 (HORMAD1) from Homo sapiens
分子名称: HORMA domain-containing protein 1
著者Yang, X.Y, Liu, X.H.
登録日2023-04-25
公開日2023-09-20
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.67 Å)
主引用文献Structural and biochemical insights into the interaction mechanism underlying HORMAD1 and its partner proteins.
Structure, 31, 2023
5IMX
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BU of 5imx by Molmil
Anaplastic lymphoma kinase (ALK) catalytic domain complexed with novel inhibitor 3-sulfonylpyrazol-4-amino pyrimidine
分子名称: 5-chloro-N~2~-{5-methyl-4-(1-methylpiperidin-4-yl)-2-[(propan-2-yl)oxy]phenyl}-N~4~-{1-methyl-3-[(propan-2-yl)sulfonyl]-1H-pyrazol-4-yl}pyrimidine-2,4-diamine, ALK tyrosine kinase receptor
著者Wang, C, Zhang, P, Dong, J.
登録日2016-03-07
公開日2016-05-04
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献Design and synthesis of novel 3-sulfonylpyrazol-4-amino pyrimidines as potent anaplastic lymphoma kinase (ALK) inhibitors.
Bioorg.Med.Chem.Lett., 26, 2016
5ZZ9
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BU of 5zz9 by Molmil
Crystal structure of Homer2 EVH1/Drebrin PPXXF complex
分子名称: Homer protein homolog 2, Peptide from Drebrin
著者Li, Z, Liu, H, Li, J, Liu, W, Zhang, M.
登録日2018-05-31
公開日2018-12-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Homer Tetramer Promotes Actin Bundling Activity of Drebrin.
Structure, 27, 2019
8V4U
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BU of 8v4u by Molmil
Structure of SARS-CoV-2 main protease in complex with a covalent inhibitor
分子名称: 3C-like proteinase nsp5, N-(methoxycarbonyl)-3-methyl-L-valyl-(4R)-N-{(1Z,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-4-(trifluoromethyl)-L-prolinamide
著者Greasley, S.E, Ferre, R.A, Liu, W.
登録日2023-11-29
公開日2024-05-15
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.819 Å)
主引用文献A Second-Generation Oral SARS-CoV-2 Main Protease Inhibitor Clinical Candidate for the Treatment of COVID-19.
J.Med.Chem., 67, 2024
8XFB
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BU of 8xfb by Molmil
Cryo-EM structure of partial dimeric WDR11-FAM91A1 complex
分子名称: Protein FAM91A1, WD repeat-containing protein 11
著者Jia, G.W, Deng, Q.H, Su, Z.M, Jia, D.
登録日2023-12-13
公開日2024-08-14
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献The WDR11 complex is a receptor for acidic-cluster-containing cargo proteins.
Cell, 187, 2024
8GU7
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BU of 8gu7 by Molmil
Selective targeting of the Beclin 2-Atg14L coiled coil complex by stapled peptides promotes autophagy and endolysosomal trafficking of GPCRs
分子名称: Beclin 1-associated autophagy-related key regulator, Beclin-2
著者Qiu, X, Zhao, Y.
登録日2022-09-11
公開日2023-07-26
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The potent BECN2-ATG14 coiled-coil interaction is selectively critical for endolysosomal degradation of GPRASP1/GASP1-associated GPCRs.
Autophagy, 19, 2023
8GT9
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BU of 8gt9 by Molmil
Selective targeting of the Beclin 2-Atg14L coiled coil complex by stapled peptides promotes autophagy and endolysosomal trafficking of GPCRs
分子名称: Beclin-2
著者Qiu, X, Zhao, Y.
登録日2022-09-07
公開日2023-07-26
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The potent BECN2-ATG14 coiled-coil interaction is selectively critical for endolysosomal degradation of GPRASP1/GASP1-associated GPCRs.
Autophagy, 19, 2023
8ID7
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BU of 8id7 by Molmil
Crystal structure of YbiW in complex with 1,5-anhydroglucitol-6-phosphate in Escherichia coli
分子名称: 1,5-anhydro-6-O-phosphono-D-glucitol, Probable dehydratase YbiW
著者Ma, K.L, Zhang, Y.
登録日2023-02-12
公開日2024-10-02
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献A Widespread Radical-Mediated Glycolysis Pathway.
J.Am.Chem.Soc., 146, 2024
8ID0
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BU of 8id0 by Molmil
Crystal structure of PflD bound to 1,5-anhydromannitol-6-phosphate in Streptococcus dysgalactiae subsp. equisimilis
分子名称: [(2R,3S,4R,5R)-3,4,5-tris(oxidanyl)oxan-2-yl]methyl dihydrogen phosphate, formate C-acetyltransferase
著者Ma, K.L, Zhang, Y.
登録日2023-02-11
公開日2024-10-02
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献A Widespread Radical-Mediated Glycolysis Pathway.
J.Am.Chem.Soc., 146, 2024
7DMW
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BU of 7dmw by Molmil
Crystal structure of CcpC regulatory domain in complex with citrate from Bacillus amyloliquefaciens
分子名称: CITRATE ANION, CcpC
著者Chen, J, Wang, L, Shang, F, Liu, W, Chen, Y, Lan, J, Bu, T, Bai, X, Xu, Y.
登録日2020-12-08
公開日2021-10-27
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Functional and structural analysis of catabolite control protein C that responds to citrate.
Sci Rep, 11, 2021
7QXN
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BU of 7qxn by Molmil
Proteasome-ZFAND5 Complex Z+A state
分子名称: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ...
著者Zhu, Y, Lu, Y.
登録日2022-01-26
公開日2023-02-08
最終更新日2024-09-04
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Molecular mechanism for activation of the 26S proteasome by ZFAND5.
Mol.Cell, 83, 2023

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