1U5R
| Crystal Structure of the TAO2 Kinase Domain: Activation and Specifity of a Ste20p MAP3K | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, MAGNESIUM ION, ... | 著者 | Zhou, T, Raman, M, Gao, Y, Earnest, S, Chen, Z, Machius, M, Cobb, M.H, Goldsmith, E.J. | 登録日 | 2004-07-28 | 公開日 | 2004-10-12 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal Structure of the TAO2 Kinase Domain; Activation and Specificity of a Ste20p MAP3K. Structure, 12, 2004
|
|
7UNK
| Structure of Importin-4 bound to the H3-H4-ASF1 histone-histone chaperone complex | 分子名称: | Histone H3, Histone H4, Histone chaperone, ... | 著者 | Bernardes, N.E, Chook, Y.M, Fung, H.Y.J, Chen, Z, Li, Y. | 登録日 | 2022-04-11 | 公開日 | 2022-09-21 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.45 Å) | 主引用文献 | Structure of IMPORTIN-4 bound to the H3-H4-ASF1 histone-histone chaperone complex. Proc.Natl.Acad.Sci.USA, 119, 2022
|
|
2PGQ
| Human thrombin mutant C191A-C220A in complex with the inhibitor PPACK | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, Thrombin heavy chain, ... | 著者 | Bush-Pelc, L.A, Marino, F, Chen, Z, Pineda, A.O, Mathews, F.S, Di Cera, E. | 登録日 | 2007-04-10 | 公開日 | 2007-07-17 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Important role of the cys-191 cys-220 disulfide bond in thrombin function and allostery J.Biol.Chem., 282, 2007
|
|
1Z71
| thrombin and P2 pyridine N-oxide inhibitor complex structure | 分子名称: | Hirudin IIIB', L17, thrombin | 著者 | Nantermet, P.G, Burgey, C.S, Robinson, K.A, Pellicore, J.M, Newton, C.L, Deng, J.Z, Lyle, T.A, Selnick, H.G, Lewis, S.D, Lucas, B.J, Krueger, J.A, Miller-Stein, C, White, R.B, Wong, B, McMasters, D.R, Wallace, A.A, Lynch Jr, J.J, Yan, Y, Chen, Z, Kuo, L, Gardell, S.J, Shafer, J.A, Vacca, J.P. | 登録日 | 2005-03-23 | 公開日 | 2005-05-17 | 最終更新日 | 2017-10-11 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | P(2) pyridine N-oxide thrombin inhibitors: a novel peptidomimetic scaffold BIOORG.MED.CHEM.LETT., 15, 2005
|
|
2PGB
| Inhibitor-free human thrombin mutant C191A-C220A | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Prothrombin, SULFATE ION | 著者 | Bush-Pelc, L.A, Marino, F, Chen, Z, Pineda, A.O, Mathews, F.S, Di Cera, E. | 登録日 | 2007-04-09 | 公開日 | 2007-07-17 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | 主引用文献 | Important role of the cys-191 cys-220 disulfide bond in thrombin function and allostery J.Biol.Chem., 282, 2007
|
|
2PKA
| REFINED 2 ANGSTROMS X-RAY CRYSTAL STRUCTURE OF PORCINE PANCREATIC KALLIKREIN A, A SPECIFIC TRYPSIN-LIKE SERINE PROTEINASE. CRYSTALLIZATION, STRUCTURE DETERMINATION, CRYSTALLOGRAPHIC REFINEMENT, STRUCTURE AND ITS COMPARISON WITH BOVINE TRYPSIN | 分子名称: | BENZAMIDINE, KALLIKREIN A | 著者 | Bode, W, Chen, Z. | 登録日 | 1984-05-21 | 公開日 | 1984-07-19 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Refined 2 A X-ray crystal structure of porcine pancreatic kallikrein A, a specific trypsin-like serine proteinase. Crystallization, structure determination, crystallographic refinement, structure and its comparison with bovine trypsin. J.Mol.Biol., 164, 1983
|
|
8Y6V
| Near-atomic structure of icosahedrally averaged jumbo bacteriophage PhiKZ capsid | 分子名称: | gp119, gp120, gp162, ... | 著者 | Yang, Y, Shao, Q, Guo, M, Han, L, Zhao, X, Wang, A, Li, X, Wang, B, Pan, J, Chen, Z, Fokine, A, Sun, L, Fang, Q. | 登録日 | 2024-02-03 | 公開日 | 2024-08-14 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Capsid structure of bacteriophage Phi KZ provides insights into assembly and stabilization of jumbo phages. Nat Commun, 15, 2024
|
|
4CQL
| Crystal structure of heterotetrameric human ketoacyl reductase complexed with NAD | 分子名称: | CARBONYL REDUCTASE FAMILY MEMBER 4, ESTRADIOL 17-BETA-DEHYDROGENASE 8, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | 著者 | Venkatesan, R, Sah-Teli, S.K, Awoniyi, L.O, Jiang, G, Prus, P, Kastaniotis, A.J, Hiltunen, J.K, Wierenga, R.K, Chen, Z. | 登録日 | 2014-02-19 | 公開日 | 2014-09-10 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Insights Into Mitochondrial Fatty Acid Synthesis from the Structure of Heterotetrameric 3-Ketoacyl-Acp Reductase/3R-Hydroxyacyl-Coa Dehydrogenase. Nat.Commun., 5, 2014
|
|
5EDK
| Crystal structure of prothrombin deletion mutant residues 146-167 ( Form II ). | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, ... | 著者 | Pozzi, N, Chen, Z, Di Cera, E. | 登録日 | 2015-10-21 | 公開日 | 2016-01-20 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (3.214 Å) | 主引用文献 | How the Linker Connecting the Two Kringles Influences Activation and Conformational Plasticity of Prothrombin. J.Biol.Chem., 291, 2016
|
|
4CQM
| Crystal structure of heterotetrameric human ketoacyl reductase complexed with NAD and NADP | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, CARBONYL REDUCTASE FAMILY MEMBER 4, ... | 著者 | Venkatesan, R, SahTeli, S.K, Awoniyi, L.O, Jiang, G, Prus, P, Kastoniotis, A.J, Hiltunen, J.K, Wierenga, R.K, Chen, Z. | 登録日 | 2014-02-19 | 公開日 | 2014-09-10 | 最終更新日 | 2014-09-17 | 実験手法 | X-RAY DIFFRACTION (2.339 Å) | 主引用文献 | Insights Into Mitochondrial Fatty Acid Synthesis from the Structure of Heterotetrameric 3-Ketoacyl-Acp Reductase/3R-Hydroxyacyl-Coa Dehydrogenase. Nat.Commun., 5, 2014
|
|
4DFI
| Crystal structure of cell adhesion molecule nectin-2/CD112 mutant FAMP | 分子名称: | Poliovirus receptor-related protein 2 | 著者 | Liu, J, Qian, X, Chen, Z, Xu, X, Gao, F, Zhang, S, Zhang, R, Qi, J, Gao, G.F, Yan, J. | 登録日 | 2012-01-23 | 公開日 | 2012-06-06 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal Structure of Cell Adhesion Molecule Nectin-2/CD112 and Its Binding to Immune Receptor DNAM-1/CD226 J.Immunol., 188, 2012
|
|
4DFH
| Crystal structure of cell adhesion molecule nectin-2/CD112 variable domain | 分子名称: | Poliovirus receptor-related protein 2 | 著者 | Liu, J, Qian, X, Chen, Z, Xu, X, Gao, F, Zhang, S, Zhang, R, Qi, J, Gao, G.F, Yan, J. | 登録日 | 2012-01-23 | 公開日 | 2012-06-06 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Crystal Structure of Cell Adhesion Molecule Nectin-2/CD112 and Its Binding to Immune Receptor DNAM-1/CD226 J.Immunol., 188, 2012
|
|
2GP9
| Crystal structure of the slow form of thrombin in a self-inhibited conformation | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Prothrombin | 著者 | Pineda, A, Chen, Z, Mathews, F.S, Di Cera, E. | 登録日 | 2006-04-17 | 公開日 | 2006-09-12 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | 主引用文献 | Crystal structure of thrombin in a self-inhibited conformation. J.Biol.Chem., 281, 2006
|
|
4RAZ
| |
4RB3
| |
4RAY
| |
4RB2
| |
4GQH
| The Conformations and Interactions of the Four-Layer Aggregate Revealed by X-ray Crystallography Diffraction Implied the Importance of Peptides at Opposite Ends in Their Assemblies | 分子名称: | Capsid protein | 著者 | Li, X.Y, Song, B.A, Hu, D.Y, Chen, X, Wang, Z.C, Zeng, M.J, Yu, D.D, Chen, Z, Jin, L.H, Yang, S. | 登録日 | 2012-08-23 | 公開日 | 2013-08-28 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (3.06 Å) | 主引用文献 | The Conformations and Interactions of the Four-Layer Aggregate Revealed by X-ray Crystallography Diffraction Implied the Importance of Peptides at Opposite Ends in Their Assemblies To be Published
|
|
4RB0
| |
4RB1
| Crystal structure of Magnetospirillum gryphiswaldense MSR-1 Fur-Mn2+-E. coli Fur box | 分子名称: | DNA (5'-D(*CP*GP*CP*GP*AP*TP*AP*AP*TP*GP*AP*TP*AP*AP*TP*CP*AP*TP*TP*AP*TP*CP*CP*GP*C)-3'), DNA-binding transcriptional dual regulator of siderophore biosynthesis and transport(Fur family), MANGANESE (II) ION | 著者 | Deng, Z, Chen, Z. | 登録日 | 2014-09-12 | 公開日 | 2015-07-15 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Mechanistic insights into metal ion activation and operator recognition by the ferric uptake regulator. Nat Commun, 6
|
|
8CIA
| |
8DYO
| Cryo-EM structure of Importin-4 bound to RanGTP | 分子名称: | GTP-binding nuclear protein GSP1/CNR1, GUANOSINE-5'-TRIPHOSPHATE, Importin-4, ... | 著者 | Bernardes, N.E, Fung, H.Y.J, Li, Y, Chen, Z, Chook, Y.M. | 登録日 | 2022-08-04 | 公開日 | 2022-09-21 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (7.1 Å) | 主引用文献 | Structure of IMPORTIN-4 bound to the H3-H4-ASF1 histone-histone chaperone complex. Proc.Natl.Acad.Sci.USA, 119, 2022
|
|
5J0I
| De novo design of protein homo-oligomers with modular hydrogen bond network-mediated specificity | 分子名称: | Designed protein 2L6HC3_12 | 著者 | Sankaran, B, Zwart, P.H, Pereira, J.H, Baker, D, Boyken, S, Chen, Z, Groves, B, Langan, R.A, Oberdorfer, G, Ford, A, Gilmore, J, Xu, C, DiMaio, F, Seelig, G. | 登録日 | 2016-03-28 | 公開日 | 2016-05-25 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.202 Å) | 主引用文献 | De novo design of protein homo-oligomers with modular hydrogen-bond network-mediated specificity. Science, 352, 2016
|
|
5J0L
| De novo design of protein homo-oligomers with modular hydrogen bond network-mediated specificity | 分子名称: | designed protein 3L6HC2_2 | 著者 | Sankaran, B, Zwart, P.H, Pereira, J.H, Baker, D, Boyken, S, Chen, Z, Groves, B, Langan, R.A, Oberdorfer, G, Ford, A, Gilmore, J, Xu, C, DiMaio, F, Seelig, G. | 登録日 | 2016-03-28 | 公開日 | 2016-07-06 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.63 Å) | 主引用文献 | De novo design of protein homo-oligomers with modular hydrogen-bond network-mediated specificity. Science, 352, 2016
|
|
5J73
| De novo design of protein homo-oligomers with modular hydrogen bond network-mediated specificity | 分子名称: | protein design 2L4HC2_9 | 著者 | Sankaran, B, Zwart, P.H, Pereira, J.H, Baker, D, Boyken, S, Chen, Z, Groves, B, Langan, R.A, Oberdorfer, G, Ford, A, Gilmore, J, Xu, C, DiMaio, F, Seelig, G. | 登録日 | 2016-04-05 | 公開日 | 2016-05-25 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.56 Å) | 主引用文献 | De novo design of protein homo-oligomers with modular hydrogen-bond network-mediated specificity. Science, 352, 2016
|
|