6X5I
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6MK1
| Cryo-EM of self-assembly peptide filament HEAT_R1 | 分子名称: | peptide HEAT_R1 | 著者 | Wang, F, Hughes, S.A, Orlova, A, Conticello, V.P, Egelman, E.H. | 登録日 | 2018-09-24 | 公開日 | 2019-06-26 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (6 Å) | 主引用文献 | Ambidextrous helical nanotubes from self-assembly of designed helical hairpin motifs. Proc.Natl.Acad.Sci.USA, 116, 2019
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8E5G
| Cryo-EM of A. veneficus cytochrome filament | 分子名称: | HEME C, c-type cytochrome | 著者 | Wang, F, Baquero, D.P, Krupovic, M, Egelman, E.H. | 登録日 | 2022-08-22 | 公開日 | 2023-05-10 | 最終更新日 | 2023-07-26 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Extracellular cytochrome nanowires appear to be ubiquitous in prokaryotes. Cell, 186, 2023
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8E5F
| Cryo-EM of P. calidifontis cytochrome filament | 分子名称: | HEME C, c-type cytochrome | 著者 | Wang, F, Cvirkaite-Krupovic, V, Krupovic, M, Egelman, E.H. | 登録日 | 2022-08-22 | 公開日 | 2023-05-10 | 最終更新日 | 2023-07-26 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Extracellular cytochrome nanowires appear to be ubiquitous in prokaryotes. Cell, 186, 2023
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5GT9
| The X-ray structure of 7beta-hydroxysteroid dehydrogenase | 分子名称: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Oxidoreductase, short chain dehydrogenase/reductase family protein | 著者 | Wang, F, Wang, R, Lv, Z, Chen, Q, Huo, X. | 登録日 | 2016-08-19 | 公開日 | 2017-05-17 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structure of NADP(+)-bound 7 beta-hydroxysteroid dehydrogenase reveals two cofactor-binding modes Acta Crystallogr F Struct Biol Commun, 73, 2017
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3K5O
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3K59
| Crystal structure of E.coli Pol II-normal DNA-dCTP ternary complex | 分子名称: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*GP*TP*GP*CP*CP*TP*AP*GP*CP*GP*TP*AP*(DOC))-3'), DNA (5'-D(*TP*AP*GP*GP*TP*AP*CP*GP*CP*TP*AP*GP*GP*CP*AP*CP*A)-3'), ... | 著者 | Yang, W, Wang, F. | 登録日 | 2009-10-06 | 公開日 | 2010-02-09 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | Structural insight into translesion synthesis by DNA Pol II Cell(Cambridge,Mass.), 139, 2009
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3K5N
| Crystal structure of E.coli Pol II-abasic DNA binary complex | 分子名称: | DNA (5'-D(*GP*TP*CP*CP*TP*GP*(3DR)*TP*AP*CP*GP*CP*TP*AP*GP*GP*CP*AP*CP*A)-3'), DNA (5'-D(*GP*TP*GP*CP*CP*TP*AP*GP*CP*GP*TP*AP*G)-3'), DNA polymerase II | 著者 | Yang, W, Wang, F. | 登録日 | 2009-10-07 | 公開日 | 2010-02-02 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | 主引用文献 | Structural insight into translesion synthesis by DNA Pol II. Cell(Cambridge,Mass.), 139, 2009
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3K5M
| Crystal structure of E.coli Pol II-abasic DNA-ddGTP Lt(-2, 2) ternary complex | 分子名称: | 2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*TP*CP*CP*TP*GP*(3DR)P*AP*CP*GP*CP*TP*AP*GP*GP*CP*AP*CP*A)-3'), ... | 著者 | Yang, W, Wang, F. | 登録日 | 2009-10-07 | 公開日 | 2010-02-02 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | 主引用文献 | Structural insight into translesion synthesis by DNA Pol II. Cell(Cambridge,Mass.), 139, 2009
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3K58
| Crystal structure of E.coli Pol II-normal DNA-dTTP ternary complex | 分子名称: | DNA (5'-D(*GP*TP*GP*CP*CP*TP*AP*GP*CP*GP*TP*AP*(DOC))-3'), DNA (5'-D(*TP*AP*AP*GP*TP*AP*CP*GP*CP*TP*AP*GP*GP*CP*AP*CP*A)-3'), DNA polymerase II, ... | 著者 | Yang, W, Wang, F. | 登録日 | 2009-10-06 | 公開日 | 2010-02-09 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Structural insight into translesion synthesis by DNA Pol II Cell(Cambridge,Mass.), 139, 2009
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3K5L
| Crystal structure of E.coli Pol II-abasic DNA-dATP Lt(0, 3) ternary complex | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*GP*TP*GP*CP*CP*TP*AP*GP*CP*GP*TP*AP*(DOC))-3'), DNA (5'-D(*TP*AP*TP*(3DR)P*GP*TP*AP*CP*GP*CP*TP*AP*GP*GP*CP*AP*CP*A)-3'), ... | 著者 | Yang, W, Wang, F. | 登録日 | 2009-10-07 | 公開日 | 2010-02-02 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural insight into translesion synthesis by DNA Pol II. Cell(Cambridge,Mass.), 139, 2009
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3K57
| Crystal structure of E.coli Pol II-normal DNA-dATP ternary complex | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*G*TP*AP*TP*GP*TP*AP*CP*GP*CP*TP*AP*GP*GP*CP*AP*CP*G)-3'), DNA (5'-D(*GP*TP*GP*CP*CP*TP*AP*GP*CP*GP*TP*AP*(DOC))-3'), ... | 著者 | Yang, W, Wang, F. | 登録日 | 2009-10-06 | 公開日 | 2010-02-09 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | 主引用文献 | Structural insight into translesion synthesis by DNA Pol II Cell(Cambridge,Mass.), 139, 2009
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6UHY
| WDR5 in complex with Myc site fragment inhibitor | 分子名称: | 1-cyclohexyl-1H-benzimidazole-5-carboxylic acid, WDR5 | 著者 | Wang, F, Fesik, S.W. | 登録日 | 2019-09-29 | 公開日 | 2020-04-15 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.26 Å) | 主引用文献 | Discovery of WD Repeat-Containing Protein 5 (WDR5)-MYC Inhibitors Using Fragment-Based Methods and Structure-Based Design. J.Med.Chem., 63, 2020
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6UHZ
| WDR5 in complex with Myc site fragment inhibitor | 分子名称: | 1-cyclohexyl-1H-benzotriazole-5-carboxylic acid, WDR5 | 著者 | Wang, F, Fesik, S.w. | 登録日 | 2019-09-29 | 公開日 | 2020-04-15 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.258 Å) | 主引用文献 | Discovery of WD Repeat-Containing Protein 5 (WDR5)-MYC Inhibitors Using Fragment-Based Methods and Structure-Based Design. J.Med.Chem., 63, 2020
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6VY1
| Cryo-EM structure of filamentous PFD from Methanocaldococcus jannaschii | 分子名称: | Prefoldin subunit alpha 2 | 著者 | Wang, F, Chen, Y.X, Ing, N.L, Hochbaum, A.I, Clark, D.S, Glover, D.J, Egelman, E.H. | 登録日 | 2020-02-25 | 公開日 | 2020-05-13 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (6 Å) | 主引用文献 | Structural Determination of a Filamentous Chaperone to Fabricate Electronically Conductive Metalloprotein Nanowires. Acs Nano, 14, 2020
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8DST
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8EWG
| Cryo-EM structure of a riboendonclease | 分子名称: | CRISPR-associated endonuclease Cas9, RNA (56-MER) | 著者 | Li, Z, Wang, F. | 登録日 | 2022-10-23 | 公開日 | 2023-08-30 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural Basis for the Ribonuclease Activity of a Thermostable CRISPR-Cas13a from Thermoclostridium caenicola. J.Mol.Biol., 435, 2023
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8GZB
| SARS-CoV-2 3CLpro | 分子名称: | 1,2-ETHANEDIOL, 2-(4-chlorophenyl)-1,3,4-oxadiazole, 3C-like proteinase nsp5 | 著者 | Wang, F, Cen, Y.X, Tian, P. | 登録日 | 2022-09-26 | 公開日 | 2023-09-27 | 最終更新日 | 2024-04-10 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Nature-inspired catalytic asymmetric rearrangement of cyclopropylcarbinyl cation. Sci Adv, 9, 2023
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6ANU
| Cryo-EM structure of F-actin complexed with the beta-III-spectrin actin-binding domain | 分子名称: | Actin, cytoplasmic 1, Spectrin beta chain, ... | 著者 | Wang, F, Orlova, A, Avery, A.W, Hays, T.S, Egelman, E.H. | 登録日 | 2017-08-14 | 公開日 | 2017-11-22 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (7 Å) | 主引用文献 | Structural basis for high-affinity actin binding revealed by a beta-III-spectrin SCA5 missense mutation. Nat Commun, 8, 2017
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3FNH
| Crystal structure of InhA bound to triclosan derivative | 分子名称: | 2-(2,4-DICHLOROPHENOXY)-5-(2-PHENYLETHYL)PHENOL, Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE | 著者 | Wang, F. | 登録日 | 2008-12-24 | 公開日 | 2009-01-20 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Triclosan Derivatives: Towards Potent Inhibitors of Drug-Sensitive and Drug-Resistant Mycobacterium tuberculosis. Chemmedchem, 4, 2009
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3FCA
| Genetic Incorporation of a Metal-ion Chelating Amino Acid into proteins as biophysical probe | 分子名称: | Cysteine synthase, ZINC ION | 著者 | Wang, F, Lee, H, Spraggon, G, Schultz, P.G. | 登録日 | 2008-11-21 | 公開日 | 2009-02-17 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.149 Å) | 主引用文献 | Genetic incorporation of a metal-ion chelating amino acid into proteins as a biophysical probe. J.Am.Chem.Soc., 131, 2009
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3FNE
| Crystal structure of InhA bound to triclosan derivative 17 | 分子名称: | 2-(2,4-DICHLOROPHENOXY)-5-(PYRIDIN-2-YLMETHYL)PHENOL, Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE | 著者 | Wang, F. | 登録日 | 2008-12-24 | 公開日 | 2009-01-20 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Triclosan Derivatives: Towards Potent Inhibitors of Drug-Sensitive and Drug-Resistant Mycobacterium tuberculosis. Chemmedchem, 4, 2009
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3FNG
| Crystal structure of InhA bound to triclosan derivative | 分子名称: | 5-(cyclohexylmethyl)-2-(2,4-dichlorophenoxy)phenol, Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE | 著者 | Wang, F. | 登録日 | 2008-12-24 | 公開日 | 2009-01-20 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | 主引用文献 | Triclosan Derivatives: Towards Potent Inhibitors of Drug-Sensitive and Drug-Resistant Mycobacterium tuberculosis. Chemmedchem, 4, 2009
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8UMY
| Atomic model of the human CTF18-RFC-PCNA-DNA ternary complex with narrow PCNA opening state II (state 6) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Chromosome transmission fidelity protein 18 homolog, DNA (20-MER), ... | 著者 | Wang, F, He, Q, Li, H. | 登録日 | 2023-10-18 | 公開日 | 2024-05-08 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (2.83 Å) | 主引用文献 | Cryo-EM reveals a nearly complete PCNA loading process and unique features of the human alternative clamp loader CTF18-RFC. Proc.Natl.Acad.Sci.USA, 121, 2024
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8UMW
| Atomic model of the human CTF18-RFC-PCNA-DNA ternary complex in the five-subunit binding state (state 4) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Chromosome transmission fidelity protein 18 homolog, DNA (20-MER), ... | 著者 | Wang, F, He, Q, Li, H. | 登録日 | 2023-10-18 | 公開日 | 2024-05-08 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (2.93 Å) | 主引用文献 | Cryo-EM reveals a nearly complete PCNA loading process and unique features of the human alternative clamp loader CTF18-RFC. Proc.Natl.Acad.Sci.USA, 121, 2024
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