3FNG
Crystal structure of InhA bound to triclosan derivative
Summary for 3FNG
Entry DOI | 10.2210/pdb3fng/pdb |
Related | 3FNE 3FNF 3FNH |
Descriptor | Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE, 5-(cyclohexylmethyl)-2-(2,4-dichlorophenoxy)phenol, ... (4 entities in total) |
Functional Keywords | inha, triclosan, tuberculosis, antibiotic resistance, fatty acid biosynthesis, lipid synthesis, nad, oxidoreductase |
Biological source | Mycobacterium tuberculosis |
Total number of polymer chains | 1 |
Total formula weight | 29569.47 |
Authors | Wang, F. (deposition date: 2008-12-24, release date: 2009-01-20, Last modification date: 2023-09-06) |
Primary citation | Freundlich, J.S.,Wang, F.,Vilcheze, C.,Gulten, G.,Langley, R.,Schiehser, G.A.,Jacobus, D.P.,Jacobs, W.R.,Sacchettini, J.C. Triclosan Derivatives: Towards Potent Inhibitors of Drug-Sensitive and Drug-Resistant Mycobacterium tuberculosis. Chemmedchem, 4:241-248, 2009 Cited by PubMed: 19130456DOI: 10.1002/cmdc.200800261 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.97 Å) |
Structure validation
Download full validation report