1TDC
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![BU of 1tdc by Molmil](/molmil-images/mine/1tdc) | STRUCTURES OF THYMIDYLATE SYNTHASE WITH A C-TERMINAL DELETION: ROLE OF THE C-TERMINUS IN ALIGNMENT OF D/UMP AND CH2H4FOLATE | 分子名称: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, THYMIDYLATE SYNTHASE | 著者 | Perry, K.M, Carreras, C.W, Chang, L.C, Santi, D.V, Stroud, R.M. | 登録日 | 1993-02-15 | 公開日 | 1993-07-15 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Structures of thymidylate synthase with a C-terminal deletion: role of the C-terminus in alignment of 2'-deoxyuridine 5'-monophosphate and 5,10-methylenetetrahydrofolate. Biochemistry, 32, 1993
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1TDA
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![BU of 1tda by Molmil](/molmil-images/mine/1tda) | STRUCTURES OF THYMIDYLATE SYNTHASE WITH A C-TERMINAL DELETION: ROLE OF THE C-TERMINUS IN ALIGNMENT OF D/UMP AND CH2H4FOLATE | 分子名称: | PHOSPHATE ION, THYMIDYLATE SYNTHASE | 著者 | Perry, K.M, Carreras, C.W, Chang, L.C, Santi, D.V, Stroud, R.M. | 登録日 | 1993-02-15 | 公開日 | 1993-07-15 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (3.09 Å) | 主引用文献 | Structures of thymidylate synthase with a C-terminal deletion: role of the C-terminus in alignment of 2'-deoxyuridine 5'-monophosphate and 5,10-methylenetetrahydrofolate. Biochemistry, 32, 1993
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1BQ1
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![BU of 1bq1 by Molmil](/molmil-images/mine/1bq1) | E. COLI THYMIDYLATE SYNTHASE MUTANT N177A IN COMPLEX WITH CB3717 AND 2'-DEOXYURIDINE 5'-MONOPHOSPHATE (DUMP) | 分子名称: | 10-PROPARGYL-5,8-DIDEAZAFOLIC ACID, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, THYMIDYLATE SYNTHASE | 著者 | Reyes, C.L, Sage, C.R, Rutenber, E.E, Finer-Moore, J.S, Stroud, R.M. | 登録日 | 1998-08-20 | 公開日 | 1999-05-18 | 最終更新日 | 2021-11-03 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Inactivity of N229A thymidylate synthase due to water-mediated effects: isolating a late stage in methyl transfer. J.Mol.Biol., 284, 1998
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1BQ2
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![BU of 1bq2 by Molmil](/molmil-images/mine/1bq2) | E. COLI THYMIDYLATE SYNTHASE MUTANT N177A | 分子名称: | PHOSPHATE ION, THYMIDYLATE SYNTHASE | 著者 | Reyes, C.L, Sage, C.R, Rutenber, E.E, Finer-Moore, J.S, Stroud, R.M. | 登録日 | 1998-08-20 | 公開日 | 1999-04-27 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Inactivity of N229A thymidylate synthase due to water-mediated effects: isolating a late stage in methyl transfer. J.Mol.Biol., 284, 1998
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1AZ5
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![BU of 1az5 by Molmil](/molmil-images/mine/1az5) | |
2OLW
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![BU of 2olw by Molmil](/molmil-images/mine/2olw) | Crystal Structure of E. coli pseudouridine synthase RluE | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, ACETIC ACID, Ribosomal large subunit pseudouridine synthase E, ... | 著者 | Pan, H, Ho, J.D, Stroud, R.M, Finer-Moore, J. | 登録日 | 2007-01-19 | 公開日 | 2007-03-13 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | The Crystal Structure of E. coli rRNA Pseudouridine Synthase RluE. J.Mol.Biol., 367, 2007
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1LCE
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![BU of 1lce by Molmil](/molmil-images/mine/1lce) | LACTOBACILLUS CASEI THYMIDYLATE SYNTHASE TERNARY COMPLEX WITH DUMP AND CH2THF | 分子名称: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 5,10-METHYLENE-6-HYDROFOLIC ACID, THYMIDYLATE SYNTHASE | 著者 | Birdsall, D.L, Finer-Moore, J, Stroud, R.M. | 登録日 | 1995-06-22 | 公開日 | 1995-10-15 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Refined structures of substrate-bound and phosphate-bound thymidylate synthase from Lactobacillus casei. J.Mol.Biol., 232, 1993
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1LCB
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![BU of 1lcb by Molmil](/molmil-images/mine/1lcb) | |
1MNA
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![BU of 1mna by Molmil](/molmil-images/mine/1mna) | Thioesterase Domain of Picromycin Polyketide Synthase (PICS TE), pH 8.0 | 分子名称: | polyketide synthase IV | 著者 | Tsai, S.-C, Lu, H, Cane, D.E, Khosla, C, Stroud, R.M. | 登録日 | 2002-09-05 | 公開日 | 2003-02-04 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Insights into channel architecture and substrate specificity from crystal structures of two macrocycle-forming thioesterases of modular polyketide synthases Biochemistry, 41, 2002
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1MNQ
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![BU of 1mnq by Molmil](/molmil-images/mine/1mnq) | Thioesterase Domain of Picromycin Polyketide Synthase (PICS TE), pH 8.4 | 分子名称: | polyketide synthase IV | 著者 | Tsai, S.-C, Lu, H, Cane, D.E, Khosla, C, Stroud, R.M. | 登録日 | 2002-09-05 | 公開日 | 2003-02-04 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Insights into channel architecture and substrate specificity from crystal structures of two macrocycle-forming thioesterases of modular polyketide synthases Biochemistry, 41, 2002
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1MO2
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![BU of 1mo2 by Molmil](/molmil-images/mine/1mo2) | Thioesterase Domain from 6-Deoxyerythronolide Synthase (DEBS TE), pH 8.5 | 分子名称: | Erythronolide synthase, modules 5 and 6 | 著者 | Tsai, S.-C, Lu, H, Cane, D.E, Khosla, C, Stroud, R.M. | 登録日 | 2002-09-05 | 公開日 | 2003-02-04 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Insights into channel architecture and substrate specificity from crystal structures of two macrocycle-forming thioesterases of modular polyketide synthases Biochemistry, 41, 2002
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1MN6
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![BU of 1mn6 by Molmil](/molmil-images/mine/1mn6) | Thioesterase Domain from Picromycin Polyketide Synthase, pH 7.6 | 分子名称: | polyketide synthase IV | 著者 | Tsai, S.-C, Lu, H, Cane, D.E, Khosla, C, Stroud, R.M. | 登録日 | 2002-09-05 | 公開日 | 2003-02-04 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Insights into channel architecture and substrate specificity from crystal structures of two macrocycle-forming thioesterases of modular polyketide synthases Biochemistry, 41, 2002
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1MZJ
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![BU of 1mzj by Molmil](/molmil-images/mine/1mzj) | Crystal Structure of the Priming beta-Ketosynthase from the R1128 Polyketide Biosynthetic Pathway | 分子名称: | ACETYL GROUP, Beta-ketoacylsynthase III, COENZYME A | 著者 | Pan, H, Tsai, S.C, Meadows, E.S, Miercke, L.J.W, Keatinge-Clay, A, O'Connell, J, Khosla, C, Stroud, R.M. | 登録日 | 2002-10-08 | 公開日 | 2002-12-11 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structure of the priming beta-ketosynthase from the
R1128 polyketide biosynthetic pathway Structure, 10
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2P2R
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![BU of 2p2r by Molmil](/molmil-images/mine/2p2r) | Crystal structure of the third KH domain of human Poly(C)-Binding Protein-2 in complex with C-rich strand of human telomeric DNA | 分子名称: | 6-AMINOPYRIMIDIN-2(1H)-ONE, C-rich strand of human telomeric DNA, Poly(rC)-binding protein 2 | 著者 | James, T.L, Stroud, R.M, Du, Z, Fenn, S, Tjhen, R, Lee, J.K. | 登録日 | 2007-03-07 | 公開日 | 2007-06-12 | 最終更新日 | 2019-07-24 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Crystal structure of the third KH domain of human poly(C)-binding protein-2 in complex with a C-rich strand of human telomeric DNA at 1.6 A resolution. Nucleic Acids Res., 35, 2007
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1LCA
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![BU of 1lca by Molmil](/molmil-images/mine/1lca) | LACTOBACILLUS CASEI THYMIDYLATE SYNTHASE TERNARY COMPLEX WITH DUMP AND CB3717 | 分子名称: | 10-PROPARGYL-5,8-DIDEAZAFOLIC ACID, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, THYMIDYLATE SYNTHASE | 著者 | Birdsall, D.L, Finer-Moore, J, Stroud, R.M. | 登録日 | 1995-06-22 | 公開日 | 1995-10-15 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Refined structures of substrate-bound and phosphate-bound thymidylate synthase from Lactobacillus casei. J.Mol.Biol., 232, 1993
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1KZJ
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![BU of 1kzj by Molmil](/molmil-images/mine/1kzj) | Crystal Structure of EcTS W80G/dUMP/CB3717 Complex | 分子名称: | 10-PROPARGYL-5,8-DIDEAZAFOLIC ACID, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, Thymidylate synthase | 著者 | Fritz, T.A, Liu, L, Finer-Moore, J.S, Stroud, R.M. | 登録日 | 2002-02-06 | 公開日 | 2002-07-03 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Tryptophan 80 and leucine 143 are critical for the hydride transfer step of thymidylate synthase by controlling active site access. Biochemistry, 41, 2002
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1KZI
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![BU of 1kzi by Molmil](/molmil-images/mine/1kzi) | Crystal Structure of EcTS/dUMP/THF Complex | 分子名称: | (2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, (6S)-5,6,7,8-TETRAHYDROFOLATE, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, ... | 著者 | Fritz, T.A, Liu, L, Finer-Moore, J.S, Stroud, R.M. | 登録日 | 2002-02-06 | 公開日 | 2002-07-03 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Tryptophan 80 and leucine 143 are critical for the hydride transfer step of thymidylate synthase by controlling active site access. Biochemistry, 41, 2002
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1KZK
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![BU of 1kzk by Molmil](/molmil-images/mine/1kzk) | JE-2147-HIV Protease Complex | 分子名称: | (4R)-3-{(2S,3S)-2-hydroxy-3-[(3-hydroxy-2-methylbenzoyl)amino]-4-phenylbutanoyl}-5,5-dimethyl-N-(2-methylbenzyl)-1,3-thiazolidine-4-carboxamide, 1,2-ETHANEDIOL, CHLORIDE ION, ... | 著者 | Reiling, K.K, Endres, N.F, Dauber, D.S, Craik, C.S, Stroud, R.M. | 登録日 | 2002-02-06 | 公開日 | 2002-04-03 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.09 Å) | 主引用文献 | Anisotropic Dynamics of the JE-2147-HIV Protease Complex:
Drug Resistance and Thermodynamic Binding Mode Examined in a 1.09 A Structure Biochemistry, 41, 2002
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2Q9A
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![BU of 2q9a by Molmil](/molmil-images/mine/2q9a) | Structure of Apo FTSY | 分子名称: | 1,2-ETHANEDIOL, Cell division protein ftsY, SULFATE ION | 著者 | Reyes, C.L, Stroud, R.M. | 登録日 | 2007-06-12 | 公開日 | 2007-07-03 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | 主引用文献 | X-ray Structures of the Signal Recognition Particle Receptor Reveal Targeting Cycle Intermediates. Plos One, 2, 2007
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2Q9B
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![BU of 2q9b by Molmil](/molmil-images/mine/2q9b) | Structure of FTSY:GMPPNP Complex | 分子名称: | 1,2-ETHANEDIOL, Cell division protein ftsY, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | 著者 | Reyes, C.L, Stroud, R.M. | 登録日 | 2007-06-12 | 公開日 | 2007-07-03 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | X-ray Structures of the Signal Recognition Particle Receptor Reveal Targeting Cycle Intermediates. Plos One, 2, 2007
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2OML
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![BU of 2oml by Molmil](/molmil-images/mine/2oml) | crystal structure of E. coli pseudouridine synthase RluE | 分子名称: | Ribosomal large subunit pseudouridine synthase E, SULFATE ION | 著者 | Pan, H, Ho, J.D, Stroud, R.M, Finer-Moore, J. | 登録日 | 2007-01-22 | 公開日 | 2007-03-13 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | The Crystal Structure of E. coli rRNA Pseudouridine Synthase RluE. J.Mol.Biol., 367, 2007
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1NM2
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![BU of 1nm2 by Molmil](/molmil-images/mine/1nm2) | Malonyl-CoA:ACP Transacylase | 分子名称: | ACETIC ACID, NICKEL (II) ION, malonyl CoA:acyl carrier protein malonyltransferase | 著者 | Keatinge-Clay, A.T, Shelat, A.A, Savage, D.F, Tsai, S, Miercke, L.J.W, O'Connell III, J.D, Khosla, C, Stroud, R.M. | 登録日 | 2003-01-08 | 公開日 | 2003-01-21 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Catalysis, Specificity, and ACP Docking Site of
Streptomyces coelicolor Malonyl-CoA:ACP Transacylase Structure, 11, 2003
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2Q9C
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![BU of 2q9c by Molmil](/molmil-images/mine/2q9c) | Structure of FTSY:GMPPNP with MGCL Complex | 分子名称: | Cell division protein ftsY, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, SULFATE ION | 著者 | Reyes, C.L, Stroud, R.M. | 登録日 | 2007-06-12 | 公開日 | 2007-07-03 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | X-ray Structures of the Signal Recognition Particle Receptor Reveal Targeting Cycle Intermediates. Plos One, 2, 2007
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1OSF
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![BU of 1osf by Molmil](/molmil-images/mine/1osf) | Human Hsp90 in complex with 17-desmethoxy-17-N,N-Dimethylaminoethylamino-Geldanamycin | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 17-DESMETHOXY-17-N,N-DIMETHYLAMINOETHYLAMINO-GELDANAMYCIN, ACETIC ACID, ... | 著者 | Jez, J.M, Chen, J.C.-H, Rastelli, G, Stroud, R.M, Santi, D.V. | 登録日 | 2003-03-19 | 公開日 | 2003-05-27 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Crystal Structure and Molecular Modeling of 17-DMAG in Complex with Human Hsp90 Chem.Biol., 10, 2003
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2SAM
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![BU of 2sam by Molmil](/molmil-images/mine/2sam) | STRUCTURE OF THE PROTEASE FROM SIMIAN IMMUNODEFICIENCY VIRUS: COMPLEX WITH AN IRREVERSIBLE NON-PEPTIDE INHIBITOR | 分子名称: | 3-(4-NITRO-PHENOXY)-PROPAN-1-OL, SIV PROTEASE | 著者 | Rose, R.B, Rose, J.R, Salto, R, Craik, C.S, Stroud, R.M. | 登録日 | 1994-07-08 | 公開日 | 1994-10-15 | 最終更新日 | 2017-11-29 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structure of the protease from simian immunodeficiency virus: complex with an irreversible nonpeptide inhibitor. Biochemistry, 32, 1993
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