4CQL
| Crystal structure of heterotetrameric human ketoacyl reductase complexed with NAD | Descriptor: | CARBONYL REDUCTASE FAMILY MEMBER 4, ESTRADIOL 17-BETA-DEHYDROGENASE 8, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | Authors: | Venkatesan, R, Sah-Teli, S.K, Awoniyi, L.O, Jiang, G, Prus, P, Kastaniotis, A.J, Hiltunen, J.K, Wierenga, R.K, Chen, Z. | Deposit date: | 2014-02-19 | Release date: | 2014-09-10 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Insights Into Mitochondrial Fatty Acid Synthesis from the Structure of Heterotetrameric 3-Ketoacyl-Acp Reductase/3R-Hydroxyacyl-Coa Dehydrogenase. Nat.Commun., 5, 2014
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4CQM
| Crystal structure of heterotetrameric human ketoacyl reductase complexed with NAD and NADP | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, CARBONYL REDUCTASE FAMILY MEMBER 4, ... | Authors: | Venkatesan, R, SahTeli, S.K, Awoniyi, L.O, Jiang, G, Prus, P, Kastoniotis, A.J, Hiltunen, J.K, Wierenga, R.K, Chen, Z. | Deposit date: | 2014-02-19 | Release date: | 2014-09-10 | Last modified: | 2014-09-17 | Method: | X-RAY DIFFRACTION (2.339 Å) | Cite: | Insights Into Mitochondrial Fatty Acid Synthesis from the Structure of Heterotetrameric 3-Ketoacyl-Acp Reductase/3R-Hydroxyacyl-Coa Dehydrogenase. Nat.Commun., 5, 2014
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2Y61
| Crystal structure of Leishmanial E65Q-TIM complexed with S-Glycidol phosphate | Descriptor: | GLYCEROL, SN-GLYCEROL-1-PHOSPHATE, SN-GLYCEROL-3-PHOSPHATE, ... | Authors: | Venkatesan, R, Alahuhta, M, Pihko, P.M, Wierenga, R.K. | Deposit date: | 2011-01-19 | Release date: | 2011-12-14 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (0.99 Å) | Cite: | High resolution crystal structures of triosephosphate isomerase complexed with its suicide inhibitors: the conformational flexibility of the catalytic glutamate in its closed, liganded active site. Protein Sci., 20, 2011
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2Y63
| Crystal structure of Leishmanial E65Q-TIM complexed with Bromohydroxyacetone phosphate | Descriptor: | (3-bromo-2-oxo-propoxy)phosphonic acid, TRIOSEPHOSPHATE ISOMERASE | Authors: | Venkatesan, R, Alahuhta, M, Pihko, P.M, Wierenga, R.K. | Deposit date: | 2011-01-19 | Release date: | 2011-12-14 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | High Resolution Crystal Structures of Triosephosphate Isomerase Complexed with its Suicide Inhibitors: The Conformational Flexibility of the Catalytic Glutamate in its Closed, Liganded Active Site. Protein Sci., 20, 2011
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2Y62
| Crystal structure of Leishmanial E65Q-TIM complexed with R-Glycidol phosphate | Descriptor: | GLYCEROL, SN-GLYCEROL-1-PHOSPHATE, SN-GLYCEROL-3-PHOSPHATE, ... | Authors: | Venkatesan, R, Alahuhta, M, Pihko, P.M, Wierenga, R.K. | Deposit date: | 2011-01-19 | Release date: | 2011-12-14 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.08 Å) | Cite: | High Resolution Crystal Structures of Triosephosphate Isomerase Complexed with its Suicide Inhibitors: The Conformational Flexibility of the Catalytic Glutamate in its Closed, Liganded Active Site. Protein Sci., 20, 2011
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4B3H
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4B3I
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4B3J
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6TNM
| E. coli aerobic trifunctional enzyme subunit-alpha | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Fatty acid oxidation complex subunit alpha, GLYCEROL, ... | Authors: | Sah-Teli, S.K, Hynonen, M.J, Wierenga, R.K, Venkatesan, R. | Deposit date: | 2019-12-09 | Release date: | 2020-03-25 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Insights into the stability and substrate specificity of the E. coli aerobic beta-oxidation trifunctional enzyme complex. J.Struct.Biol., 210, 2020
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2YIM
| The enolisation chemistry of a thioester-dependent racemase: the 1.4 A crystal structure of a complex with a planar reaction intermediate analogue | Descriptor: | 2-METHYLACETOACETYL COA, GLYCEROL, PHOSPHATE ION, ... | Authors: | Sharma, S, Bhaumik, P, Venkatesan, R, Hiltunen, J.K, Conzelmann, E, Juffer, A.H, Wierenga, R.K. | Deposit date: | 2011-05-16 | Release date: | 2012-03-28 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.41 Å) | Cite: | The Enolization Chemistry of a Thioester-Dependent Racemase: The 1.4 A Crystal Structure of a Reaction Intermediate Complex Characterized by Detailed Qm/Mm Calculations. J Phys Chem B, 116, 2012
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7AI3
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7AI2
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6YSV
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6YSW
| E. coli anaerobic trifunctional enzyme subunit-alpha in complex with coenzyme A | Descriptor: | COENZYME A, Fatty acid oxidation complex subunit alpha, SULFATE ION | Authors: | Sah-Teli, S.K, Hynonen, M.J, Wierenga, R.K, Venkatesan, R. | Deposit date: | 2020-04-23 | Release date: | 2021-05-12 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.82 Å) | Cite: | Structural basis for different membrane-binding properties of E. coli anaerobic and human mitochondrial beta-oxidation trifunctional enzymes Structure, 2023
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8BNR
| Escherichia coli anaerobic fatty acid beta oxidation trifunctional enzyme (anEcTFE) octameric complex | Descriptor: | 3-ketoacyl-CoA thiolase FadI, Fatty acid oxidation complex subunit alpha | Authors: | Sah-Teli, S.K, Pinkas, M, Novacek, J, Venkatesan, R. | Deposit date: | 2022-11-14 | Release date: | 2023-05-17 | Last modified: | 2023-11-29 | Method: | ELECTRON MICROSCOPY (10.3 Å) | Cite: | Structural basis for different membrane-binding properties of E. coli anaerobic and human mitochondrial beta-oxidation trifunctional enzymes. Structure, 31, 2023
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8BNU
| Escherichia coli anaerobic fatty acid beta oxidation trifunctional enzyme (anEcTFE) tetrameric complex | Descriptor: | 3-ketoacyl-CoA thiolase FadI, Fatty acid oxidation complex subunit alpha | Authors: | Sah-Teli, S.K, Pinkas, M, Novacek, J, Venkatesan, R. | Deposit date: | 2022-11-14 | Release date: | 2023-05-17 | Last modified: | 2023-07-19 | Method: | ELECTRON MICROSCOPY (3.55 Å) | Cite: | Structural basis for different membrane-binding properties of E. coli anaerobic and human mitochondrial beta-oxidation trifunctional enzymes. Structure, 31, 2023
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8BRJ
| Escherichia coli anaerobic fatty acid beta oxidation trifunctional enzyme (anEcTFE) trimeric complex | Descriptor: | 3-ketoacyl-CoA thiolase FadI, Fatty acid oxidation complex subunit alpha | Authors: | Sah-Teli, S.K, Pinkas, M, Novacek, J, Venkatesan, R. | Deposit date: | 2022-11-23 | Release date: | 2023-05-17 | Last modified: | 2023-07-19 | Method: | ELECTRON MICROSCOPY (4.08 Å) | Cite: | Structural basis for different membrane-binding properties of E. coli anaerobic and human mitochondrial beta-oxidation trifunctional enzymes. Structure, 31, 2023
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8OQO
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8OQL
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8OQN
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8OQM
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7O1I
| Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme alpha-E141A mutant | Descriptor: | 3-hydroxyacyl-CoA dehydrogenase, COENZYME A, GLYCEROL, ... | Authors: | Dalwani, S, Wierenga, R.K, Venkatesan, R. | Deposit date: | 2021-03-29 | Release date: | 2021-08-25 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Substrate specificity and conformational flexibility properties of the Mycobacterium tuberculosis beta-oxidation trifunctional enzyme. J.Struct.Biol., 213, 2021
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7O1G
| Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme alpha-E141A-H462A, beta-C92A mutant | Descriptor: | 3-hydroxyacyl-CoA dehydrogenase, Putative acyltransferase Rv0859, SULFATE ION | Authors: | Dalwani, S, Wierenga, R.K, Venkatesan, R. | Deposit date: | 2021-03-29 | Release date: | 2021-08-25 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (3.03 Å) | Cite: | Substrate specificity and conformational flexibility properties of the Mycobacterium tuberculosis beta-oxidation trifunctional enzyme. J.Struct.Biol., 213, 2021
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7O1K
| Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme alpha-E141A, beta-C92A mutant | Descriptor: | 3-hydroxyacyl-CoA dehydrogenase, GLYCEROL, Putative acyltransferase Rv0859, ... | Authors: | Dalwani, S, Wierenga, R.K, Venkatesan, R. | Deposit date: | 2021-03-29 | Release date: | 2021-08-25 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.86 Å) | Cite: | Substrate specificity and conformational flexibility properties of the Mycobacterium tuberculosis beta-oxidation trifunctional enzyme. J.Struct.Biol., 213, 2021
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7O4V
| Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with oxidized nicotinamide adenine dinucleotide | Descriptor: | 3-hydroxyacyl-CoA dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Putative acyltransferase Rv0859, ... | Authors: | Dalwani, S, Wierenga, R.K, Venkatesan, R. | Deposit date: | 2021-04-07 | Release date: | 2021-08-25 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.42 Å) | Cite: | Substrate specificity and conformational flexibility properties of the Mycobacterium tuberculosis beta-oxidation trifunctional enzyme. J.Struct.Biol., 213, 2021
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