8R6T
| NMR solution structure of thyropin IrThy-Cd from the hard tick Ixodes ricinus | Descriptor: | Putative two thyropin protein (Fragment) | Authors: | Srb, P, Veverka, V, Matouskova, Z, Orsaghova, K, Mares, M. | Deposit date: | 2023-11-23 | Release date: | 2024-02-28 | Last modified: | 2024-10-09 | Method: | SOLUTION NMR | Cite: | An Unusual Two-Domain Thyropin from Tick Saliva: NMR Solution Structure and Highly Selective Inhibition of Cysteine Cathepsins Modulated by Glycosaminoglycans. Int J Mol Sci, 25, 2024
|
|
6YY4
| Parallel 17-mer DNA G-quadruplex | Descriptor: | DNA (5'-D(*GP*GP*GP*TP*GP*GP*GP*AP*AP*GP*GP*GP*TP*GP*GP*GP*A)-3') | Authors: | Srb, P, Curtis, C, Veverka, V. | Deposit date: | 2020-05-04 | Release date: | 2021-01-20 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | Overlapping but distinct: a new model for G-quadruplex biochemical specificity. Nucleic Acids Res., 49, 2021
|
|
2F77
| Solution structure of the R55F mutant of M-PMV matrix protein (p10) | Descriptor: | Core protein p10 | Authors: | Vlach, J, Lipov, J, Veverka, V, Lang, J, Srb, P, Rumlova, M, Hunter, E, Ruml, T, Hrabal, R. | Deposit date: | 2005-11-30 | Release date: | 2006-12-05 | Last modified: | 2024-05-08 | Method: | SOLUTION NMR | Cite: | D-retrovirus morphogenetic switch driven by the targeting signal accessibility to Tctex-1 of dynein. Proc.Natl.Acad.Sci.USA, 105, 2008
|
|
2F76
| Solution structure of the M-PMV wild type matrix protein (p10) | Descriptor: | Core protein p10 | Authors: | Vlach, J, Lipov, J, Veverka, V, Lang, J, Srb, P, Rumlova, M, Hunter, E, Ruml, T, Hrabal, R. | Deposit date: | 2005-11-30 | Release date: | 2006-12-05 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | D-retrovirus morphogenetic switch driven by the targeting signal accessibility to Tctex-1 of dynein. Proc.Natl.Acad.Sci.USA, 105, 2008
|
|
6FVC
| Protein environment affects the water-tryptophan binding mode. Molecular dynamics simulations of Engrailed homeodomain mutants | Descriptor: | Segmentation polarity homeobox protein engrailed | Authors: | Trosanova, Z, Zachrdla, M, Jansen, S, Srb, P, Zidek, L, Kozelka, J. | Deposit date: | 2018-03-02 | Release date: | 2019-04-03 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | Protein environment affects the water-tryptophan binding mode. MD, QM/MM, and NMR studies of engrailed homeodomain mutants. Phys Chem Chem Phys, 20, 2018
|
|
7OMK
| The NMR structure of the Zf-GRF domains from the mouse Endonuclease VIII-LIKE 3 (mNEIL3) | Descriptor: | Endonuclease 8-like 3 | Authors: | Dinesh, D.C, Huskova, A, Srb, P, Veverka, V, Silhan, J. | Deposit date: | 2021-05-24 | Release date: | 2022-06-01 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | Model of abasic site DNA cross-link repair; from the architecture of NEIL3 DNA binding domains to the X-structure model. Nucleic Acids Res., 50, 2022
|
|
6TVM
| LEDGF/p75 dimer (residues 345-467) | Descriptor: | PC4 and SFRS1-interacting protein | Authors: | Lux, V, Veverka, V. | Deposit date: | 2020-01-10 | Release date: | 2020-09-09 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | Molecular Mechanism of LEDGF/p75 Dimerization. Structure, 28, 2020
|
|
5YI9
| Solution structure of the LEDGF/p75 IBD - JPO2 (aa 56-91) complex | Descriptor: | PC4 and SFRS1-interacting protein,Cell division cycle-associated 7-like protein | Authors: | Veverka, V. | Deposit date: | 2017-10-03 | Release date: | 2018-08-15 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Affinity switching of the LEDGF/p75 IBD interactome is governed by kinase-dependent phosphorylation. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
|
|
4NC7
| N-terminal domain of delta-subunit of RNA polymerase complexed with I3C and nickel ions | Descriptor: | 5-amino-2,4,6-triiodobenzene-1,3-dicarboxylic acid, DNA-directed RNA polymerase subunit delta, NICKEL (II) ION | Authors: | Demo, G, Papouskova, V, Komarek, J, Sanderova, H, Rabatinova, A, Krasny, L, Zidek, L, Sklenar, V, Wimmerova, M. | Deposit date: | 2013-10-24 | Release date: | 2014-07-02 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | X-ray vs. NMR structure of N-terminal domain of delta-subunit of RNA polymerase. J.Struct.Biol., 187, 2014
|
|
4NC8
| N-terminal domain of delta-subunit of RNA polymerase complexed with nickel ions | Descriptor: | DNA-directed RNA polymerase subunit delta, NICKEL (II) ION | Authors: | Demo, G, Papouskova, V, Komarek, J, Sanderova, H, Rabatinova, A, Krasny, L, Zidek, L, Sklenar, V, Wimmerova, M. | Deposit date: | 2013-10-24 | Release date: | 2014-07-02 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.17 Å) | Cite: | X-ray vs. NMR structure of N-terminal domain of delta-subunit of RNA polymerase. J.Struct.Biol., 187, 2014
|
|
8PEP
| H3K36me2 nucleosome-LEDGF/p75 PWWP domain complex - pose 2 | Descriptor: | Histone H2A, Histone H2B 1.1, Histone H3, ... | Authors: | Koutna, E, Kouba, T, Veverka, V. | Deposit date: | 2023-06-14 | Release date: | 2023-08-16 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (3.33 Å) | Cite: | Multivalency of nucleosome recognition by LEDGF. Nucleic Acids Res., 51, 2023
|
|
8PC5
| H3K36me3 nucleosome-LEDGF/p75 PWWP domain complex | Descriptor: | Histone H2A, Histone H2B 1.1, Histone H3, ... | Authors: | Koutna, E, Kouba, T, Veverka, V. | Deposit date: | 2023-06-09 | Release date: | 2023-08-16 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (3.02 Å) | Cite: | Multivalency of nucleosome recognition by LEDGF. Nucleic Acids Res., 51, 2023
|
|
8PEO
| H3K36me2 nucleosome-LEDGF/p75 PWWP domain complex | Descriptor: | Histone H2A, Histone H2B 1.1, Histone H3, ... | Authors: | Koutna, E, Kouba, T, Veverka, V. | Deposit date: | 2023-06-14 | Release date: | 2023-08-16 | Last modified: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (2.69 Å) | Cite: | Multivalency of nucleosome recognition by LEDGF. Nucleic Acids Res., 51, 2023
|
|
8PC6
| H3K36me3 nucleosome-LEDGF/p75 PWWP domain complex - pose 2 | Descriptor: | Histone H2A, Histone H2B 1.1, Histone H3, ... | Authors: | Koutna, E, Kouba, T, Veverka, V. | Deposit date: | 2023-06-09 | Release date: | 2023-08-16 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (3.04 Å) | Cite: | Multivalency of nucleosome recognition by LEDGF. Nucleic Acids Res., 51, 2023
|
|
6R0J
| |
6RFM
| |
6TRJ
| LEDGF/p75 IBD dimer | Descriptor: | PC4 and SFRS1-interacting protein | Authors: | Kugler, M, Brynda, J. | Deposit date: | 2019-12-19 | Release date: | 2020-09-09 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Fine-tuning of the LEDGF/p75 interaction network by dimerization Structure
|
|
6EMR
| |
6EMP
| Solution structure of the LEDGF/p75 IBD - POGZ (aa 1370-1404) complex | Descriptor: | PC4 and SFRS1-interacting protein,Pogo transposable element with ZNF domain | Authors: | Veverka, V. | Deposit date: | 2017-10-03 | Release date: | 2018-07-25 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | Affinity switching of the LEDGF/p75 IBD interactome is governed by kinase-dependent phosphorylation. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
|
|
6EMO
| Solution structure of the LEDGF/p75 IBD - JPO2 (aa 1-32) complex | Descriptor: | PC4 and SFRS1-interacting protein,LEDGF/p75 IBD-JPO2 M1 | Authors: | Veverka, V. | Deposit date: | 2017-10-03 | Release date: | 2018-07-25 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | Affinity switching of the LEDGF/p75 IBD interactome is governed by kinase-dependent phosphorylation. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
|
|
6EMQ
| Solution structure of the LEDGF/p75 IBD - MLL1 (aa 111-160) complex | Descriptor: | PC4 and SFRS1-interacting protein,Histone-lysine N-methyltransferase 2A | Authors: | Veverka, V. | Deposit date: | 2017-10-03 | Release date: | 2018-08-01 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | Affinity switching of the LEDGF/p75 IBD interactome is governed by kinase-dependent phosphorylation. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
|
|
7OYN
| Carbonic anhydrase II in complex with Hit3 (MH57) | Descriptor: | Carbonic anhydrase 2, Hit3 (MH57), ZINC ION | Authors: | Kugler, M, Brynda, J, Rezacova, P. | Deposit date: | 2021-06-24 | Release date: | 2023-01-18 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (0.98 Å) | Cite: | Identification of specific carbonic anhydrase inhibitors via in situ click chemistry, phage-display and synthetic peptide libraries: comparison of the methods and structural study. Rsc Med Chem, 14, 2023
|
|
7OYP
| Carbonic anhydrase II in complex with Hit3-t1 (MH172) | Descriptor: | (2S)-3-oxidanyl-2-[2-[(4-sulfamoylphenyl)methoxyamino]ethanoylamino]propanamide, 4-methylbenzenesulfonamide, Carbonic anhydrase 2, ... | Authors: | Kugler, M, Brynda, J, Rezacova, P. | Deposit date: | 2021-06-24 | Release date: | 2023-01-18 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.05 Å) | Cite: | Identification of specific carbonic anhydrase inhibitors via in situ click chemistry, phage-display and synthetic peptide libraries: comparison of the methods and structural study. Rsc Med Chem, 14, 2023
|
|
7OYR
| Carbonic anhydrase II in complex with Hit3-t4 (MH181) | Descriptor: | Carbonic anhydrase 2, Hit3-t4 (MH181), ZINC ION | Authors: | Kugler, M, Brynda, J, Rezacova, P. | Deposit date: | 2021-06-24 | Release date: | 2023-01-18 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | Identification of specific carbonic anhydrase inhibitors via in situ click chemistry, phage-display and synthetic peptide libraries: comparison of the methods and structural study. Rsc Med Chem, 14, 2023
|
|
7OYQ
| Carbonic anhydrase II in complex with Hit3-t2 (MH174) | Descriptor: | Carbonic anhydrase 2, Hit3-t2 (MH174), ZINC ION | Authors: | Kugler, M, Brynda, J, Rezacova, P. | Deposit date: | 2021-06-24 | Release date: | 2023-01-18 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | Identification of specific carbonic anhydrase inhibitors via in situ click chemistry, phage-display and synthetic peptide libraries: comparison of the methods and structural study. Rsc Med Chem, 14, 2023
|
|