1I27
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![BU of 1i27 by Molmil](/molmil-images/mine/1i27) | CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF THE RAP74 SUBUNIT OF HUMAN TRANSCRIPTION FACTOR IIF (TFIIF) | Descriptor: | TRANSCRIPTION FACTOR IIF, ZINC ION | Authors: | Kamada, K, De Angelis, J, Roeder, R.G, Burley, S.K. | Deposit date: | 2001-02-07 | Release date: | 2001-03-07 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.02 Å) | Cite: | Crystal structure of the C-terminal domain of the RAP74 subunit of human transcription factor IIF. Proc.Natl.Acad.Sci.USA, 98, 2001
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6DRD
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![BU of 6drd by Molmil](/molmil-images/mine/6drd) | RNA Pol II(G) | Descriptor: | DNA-directed RNA polymerase II subunit GRINL1A, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11-a, ... | Authors: | Yu, X, Jishage, M, Shi, Y, Ganesan, S, Sali, A, Chait, B.T, Asturias, F, Roeder, R.G. | Deposit date: | 2018-06-11 | Release date: | 2019-06-12 | Last modified: | 2019-12-04 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Architecture of Pol II(G) and molecular mechanism of transcription regulation by Gdown1. Nat. Struct. Mol. Biol., 25, 2018
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1J2X
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![BU of 1j2x by Molmil](/molmil-images/mine/1j2x) | Crystal structure of RAP74 C-terminal domain complexed with FCP1 C-terminal peptide | Descriptor: | RNA polymerase II CTD phosphatase, SULFATE ION, Transcription initiation factor IIF, ... | Authors: | Kamada, K, Roeder, R.G, Burley, S.K. | Deposit date: | 2003-01-15 | Release date: | 2003-01-30 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Molecular mechanism of recruitment of TFIIF- associating RNA polymerase C-terminal domain phosphatase (FCP1) by transcription factor IIF Proc.Natl.Acad.Sci.USA, 100, 2003
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1JFI
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![BU of 1jfi by Molmil](/molmil-images/mine/1jfi) | Crystal Structure of the NC2-TBP-DNA Ternary Complex | Descriptor: | 5'-D(*G*GP*AP*GP*CP*CP*CP*TP*TP*TP*TP*AP*TP*AP*GP*CP*CP*AP*A)-3', 5'-D(*TP*TP*GP*GP*CP*TP*AP*TP*AP*AP*AP*AP*GP*GP*GP*CP*TP*CP*C)-3', TATA-BOX-BINDING PROTEIN (TBP), ... | Authors: | Kamada, K, Shu, F, Chen, H, Malik, S, Stelzer, G, Roeder, R.G, Meisterernst, M, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2001-06-20 | Release date: | 2001-07-11 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.62 Å) | Cite: | Crystal structure of negative cofactor 2 recognizing the TBP-DNA transcription complex. Cell(Cambridge,Mass.), 106, 2001
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1CDW
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![BU of 1cdw by Molmil](/molmil-images/mine/1cdw) | HUMAN TBP CORE DOMAIN COMPLEXED WITH DNA | Descriptor: | DNA (5'-D(*CP*AP*GP*CP*CP*TP*TP*TP*TP*AP*TP*AP*GP*CP*AP*G)-3'), DNA (5'-D(*CP*TP*GP*CP*TP*AP*TP*AP*AP*AP*AP*GP*GP*CP*TP*G)-3'), PROTEIN (TATA BINDING PROTEIN (TBP)) | Authors: | Nikolov, D.B, Chen, H, Halay, E.D, Hoffmann, A, Roeder, R.G, Burley, S.K. | Deposit date: | 1996-04-11 | Release date: | 1996-12-23 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of a human TATA box-binding protein/TATA element complex. Proc.Natl.Acad.Sci.USA, 93, 1996
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1AN4
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![BU of 1an4 by Molmil](/molmil-images/mine/1an4) | STRUCTURE AND FUNCTION OF THE B/HLH/Z DOMAIN OF USF | Descriptor: | DNA (5'-D(*CP*AP*CP*CP*CP*GP*GP*TP*CP*AP*CP*GP*TP*GP*GP*CP*C P*TP*AP*CP*A)-3'), DNA (5'-D(*GP*TP*GP*TP*AP*GP*GP*CP*CP*AP*CP*GP*TP*GP*AP*CP*C P*GP*GP*GP*T)-3'), PROTEIN (UPSTREAM STIMULATORY FACTOR) | Authors: | Ferre-D'Amare, A.R, Pognonec, P, Roeder, R.G, Burley, S.K. | Deposit date: | 1997-03-15 | Release date: | 1997-09-17 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structure and function of the b/HLH/Z domain of USF. EMBO J., 13, 1994
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2H7B
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![BU of 2h7b by Molmil](/molmil-images/mine/2h7b) | Solution structure of the eTAFH domain from the human leukemia-associated fusion protein AML1-ETO | Descriptor: | Core-binding factor, ML1-ETO | Authors: | Plevin, M.J, Zhang, J, Guo, C, Roeder, R.G, Ikura, M. | Deposit date: | 2006-06-01 | Release date: | 2006-07-11 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | The acute myeloid leukemia fusion protein AML1-ETO targets E proteins via a paired amphipathic helix-like TBP-associated factor homology domain Proc.Natl.Acad.Sci.USA, 103, 2006
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1TAF
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![BU of 1taf by Molmil](/molmil-images/mine/1taf) | DROSOPHILA TBP ASSOCIATED FACTORS DTAFII42/DTAFII62 HETEROTETRAMER | Descriptor: | TFIID TBP ASSOCIATED FACTOR 42, TFIID TBP ASSOCIATED FACTOR 62, ZINC ION | Authors: | Xie, X, Kokubo, T, Cohen, S.L, Mirza, U.A, Hoffmann, A, Chait, B.T, Roeder, R.G, Nakatani, Y, Burley, S.K. | Deposit date: | 1996-06-01 | Release date: | 1996-12-07 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural similarity between TAFs and the heterotetrameric core of the histone octamer. Nature, 380, 1996
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1VOL
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![BU of 1vol by Molmil](/molmil-images/mine/1vol) | TFIIB (HUMAN CORE DOMAIN)/TBP (A.THALIANA)/TATA ELEMENT TERNARY COMPLEX | Descriptor: | DNA (5'-D(*CP*AP*GP*CP*CP*CP*TP*TP*TP*TP*AP*TP*AP*GP*CP*C)-3'), DNA (5'-D(*GP*GP*CP*TP*AP*TP*AP*AP*AP*AP*GP*GP*GP*CP*TP*G)-3'), PROTEIN (TATA BINDING PROTEIN (TBP)), ... | Authors: | Nikolov, D.B, Chen, H, Halay, E.D, Usheva, A.U, Hisatake, K, Lee, D.K, Roeder, R.G, Burley, S.K. | Deposit date: | 1996-04-29 | Release date: | 1996-11-08 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of a TFIIB-TBP-TATA-element ternary complex. Nature, 377, 1995
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8I60
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![BU of 8i60 by Molmil](/molmil-images/mine/8i60) | |
7FAW
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![BU of 7faw by Molmil](/molmil-images/mine/7faw) | Structure of LW domain from Yeast | Descriptor: | Transcription elongation factor S-II | Authors: | Liao, S, Gao, J, Tu, X. | Deposit date: | 2021-07-07 | Release date: | 2022-07-13 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.438 Å) | Cite: | Structural basis for evolutionarily conserved interactions between TFIIS and Paf1C. Int.J.Biol.Macromol., 253, 2023
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7FAX
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![BU of 7fax by Molmil](/molmil-images/mine/7fax) | |
7XGW
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![BU of 7xgw by Molmil](/molmil-images/mine/7xgw) | |
6ZLY
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![BU of 6zly by Molmil](/molmil-images/mine/6zly) | |
7XUR
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![BU of 7xur by Molmil](/molmil-images/mine/7xur) | |
4JOL
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![BU of 4jol by Molmil](/molmil-images/mine/4jol) | |
8T1I
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![BU of 8t1i by Molmil](/molmil-images/mine/8t1i) | Atomic model of the mammalian Mediator complex with MED26 subunit | Descriptor: | Mediator of RNA polymerase II transcription subunit 1, Mediator of RNA polymerase II transcription subunit 10, Mediator of RNA polymerase II transcription subunit 11, ... | Authors: | Zhao, H, Asturias, F. | Deposit date: | 2023-06-02 | Release date: | 2024-06-12 | Last modified: | 2024-08-07 | Method: | ELECTRON MICROSCOPY (4.68 Å) | Cite: | An IDR-dependent mechanism for nuclear receptor control of Mediator interaction with RNA polymerase II. Mol.Cell, 84, 2024
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8T9D
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![BU of 8t9d by Molmil](/molmil-images/mine/8t9d) | CryoEM structure of TR-TRAP | Descriptor: | Mediator of RNA polymerase II transcription subunit 1, Mediator of RNA polymerase II transcription subunit 10, Mediator of RNA polymerase II transcription subunit 11, ... | Authors: | Zhao, H, Asturias, F. | Deposit date: | 2023-06-23 | Release date: | 2024-07-03 | Last modified: | 2024-08-07 | Method: | ELECTRON MICROSCOPY (4.66 Å) | Cite: | An IDR-dependent mechanism for nuclear receptor control of Mediator interaction with RNA polymerase II. Mol.Cell, 84, 2024
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6QJ5
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![BU of 6qj5 by Molmil](/molmil-images/mine/6qj5) | X-ray structure of PPARgamma LBD with the ligand NV1380 | Descriptor: | (2~{S})-3-methyl-2-[(4-octoxyphenyl)carbonylamino]butanoic acid, Peroxisome proliferator-activated receptor gamma | Authors: | Pochetti, G, Montanari, R, Capelli, D. | Deposit date: | 2019-01-22 | Release date: | 2020-02-05 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A Novel N-Substituted Valine Derivative with Unique Peroxisome Proliferator-Activated Receptor gamma Binding Properties and Biological Activities. J.Med.Chem., 63, 2020
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6O7G
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![BU of 6o7g by Molmil](/molmil-images/mine/6o7g) | |
6AF0
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![BU of 6af0 by Molmil](/molmil-images/mine/6af0) | Structure of Ctr9, Paf1 and Cdc73 ternary complex from Myceliophthora thermophila | Descriptor: | Cdc73 protein, Ctr9 protein, Paf1 protein | Authors: | Wang, Z, Deng, P, Zhou, Y. | Deposit date: | 2018-08-07 | Release date: | 2018-09-19 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.88 Å) | Cite: | Transcriptional elongation factor Paf1 core complex adopts a spirally wrapped solenoidal topology. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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5HJB
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![BU of 5hjb by Molmil](/molmil-images/mine/5hjb) | AF9 YEATS in complex with histone H3 Crotonylation at K9 | Descriptor: | Protein AF-9, peptide of Histone H3.1 | Authors: | Li, Y.Y, Zhao, D, Guan, H.P, Li, H.T. | Deposit date: | 2016-01-12 | Release date: | 2016-04-20 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Molecular Coupling of Histone Crotonylation and Active Transcription by AF9 YEATS Domain Mol.Cell, 62, 2016
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5HJD
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![BU of 5hjd by Molmil](/molmil-images/mine/5hjd) | AF9 YEATS in complex with histone H3 Crotonylation at K18 | Descriptor: | COPPER (II) ION, Protein AF-9, SULFATE ION, ... | Authors: | Li, Y.Y, Zhao, D, Guan, H.P, Li, H.T. | Deposit date: | 2016-01-13 | Release date: | 2016-04-20 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.806 Å) | Cite: | Molecular Coupling of Histone Crotonylation and Active Transcription by AF9 YEATS Domain. Mol.Cell, 62, 2016
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5HJC
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![BU of 5hjc by Molmil](/molmil-images/mine/5hjc) | BRD3 second bromodomain in complex with histone H3 acetylation at K18 | Descriptor: | 1,2-ETHANEDIOL, Bromodomain-containing protein 3, CHLORIDE ION, ... | Authors: | Li, Y.Y, Zhao, D, Guan, H.P, Li, H.T. | Deposit date: | 2016-01-13 | Release date: | 2016-04-20 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Molecular Coupling of Histone Crotonylation and Active Transcription by AF9 YEATS Domain Mol.Cell, 62, 2016
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1C9B
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![BU of 1c9b by Molmil](/molmil-images/mine/1c9b) | |